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Application of a novel in vivo imaging approach to measure pulmonary vascular responses in mice.

Preissner M, Murrie RP, Bresee C, Carnibella RP, Fouras A, Weir EK, Dubsky S, Pinar IP, Jones HD.

Physiol Rep. 2018 Sep;6(19):e13875. doi: 10.14814/phy2.13875.


Role of Extracellular Matrix in the Pathogenesis of Pulmonary Arterial Hypertension.

Thenappan T, Chan SY, Weir EK.

Am J Physiol Heart Circ Physiol. 2018 Aug 24. doi: 10.1152/ajpheart.00136.2018. [Epub ahead of print]


Could this be whooping cough?

Nee P, Weir E, Vardhan M, Vaidya A.

Emerg Med J. 2018 Oct;35(10):639-642. doi: 10.1136/emermed-2018-207792. Epub 2018 Aug 10.


Panayiotopoulos syndrome and benign partial epilepsy with centro-temporal spikes: A comparative incidence study.

Weir E, Gibbs J, Appleton R.

Seizure. 2018 Apr;57:66-69. doi: 10.1016/j.seizure.2018.03.002. Epub 2018 Mar 5.


Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension.

Prins KW, Rose L, Archer SL, Pritzker M, Weir EK, Kazmirczak F, Misialek JR, Thenappan T.

Am J Respir Crit Care Med. 2018 Jun 1;197(11):1496-1499. doi: 10.1164/rccm.201712-2405LE. No abstract available.


The Nitric Oxide Pathway-A Potential Target for Precision Medicine in Pulmonary Arterial Hypertension.

Thenappan T, Weir EK.

Am J Cardiol. 2017 Oct 15;120(8S):S69-S70. doi: 10.1016/j.amjcard.2017.06.011. No abstract available.


Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.

Prins KW, Archer SL, Pritzker M, Rose L, Weir EK, Sharma A, Thenappan T.

J Heart Lung Transplant. 2018 Mar;37(3):376-384. doi: 10.1016/j.healun.2017.08.011. Epub 2017 Sep 1.


Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

Nagaraj C, Tabeling C, Nagy BM, Jain PP, Marsh LM, Papp R, Pienn M, Witzenrath M, Ghanim B, Klepetko W, Weir EK, Heschl S, Kwapiszewska G, Olschewski A, Olschewski H.

Eur Respir J. 2017 Jul 20;50(1). pii: 1601651. doi: 10.1183/13993003.01651-2016. Print 2017 Jul.


Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment.

Thenappan T, Archer SL, Weir EK.

Pulm Circ. 2017 Feb 1;7(1):275. doi: 10.1177/2045893216681025. eCollection 2017 Mar. No abstract available.


Establishing a deanery teaching programme for trainees sitting the MRCPCH clinical examination.

Harry C, Weir E, Grattan R, Skeoch C, Evans P.

J R Coll Physicians Edinb. 2017 Jun;47(2):159-163. doi: 10.4997/JRCPE.2017.214.


Report on bursary applications, 2016.

Orellana J, Weir E.

Lab Anim. 2017 Jun;51(3):325-327. doi: 10.1177/0023677217707426. No abstract available.


Dementia-friendly communities: where home care and mental health intersect.

Weir E, Seitz D.

CMAJ. 2017 Apr 24;189(16):E581-E582. doi: 10.1503/cmaj.170370. No abstract available.


Using the Upshur principles to discuss medical fitness to drive.

Weir E.

Can Fam Physician. 2017 Apr;63(4):269-272. No abstract available.


Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension.

Prins KW, Weir EK, Archer SL, Markowitz J, Rose L, Pritzker M, Madlon-Kay R, Thenappan T.

Pulm Circ. 2016 Dec;6(4):576-585. doi: 10.1086/688879.


Cardiopulmonary exercise testing in children with cystic fibrosis: one centre's experience.

Weir E, Burns PD, Devenny A, Young D, Paton JY.

Arch Dis Child. 2017 May;102(5):440-444. doi: 10.1136/archdischild-2016-310651. Epub 2016 Dec 5.


Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012.

Anand V, Roy SS, Archer SL, Weir EK, Garg SK, Duval S, Thenappan T.

JAMA Cardiol. 2016 Dec 1;1(9):1021-1029. doi: 10.1001/jamacardio.2016.3591.


The AAA ATPase MDN1 Acts as a SUMO-Targeted Regulator in Mammalian Pre-ribosome Remodeling.

Raman N, Weir E, Müller S.

Mol Cell. 2016 Nov 3;64(3):607-615. doi: 10.1016/j.molcel.2016.09.039.


Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension.

Nagaraj C, Tang B, Nagy BM, Papp R, Jain PP, Marsh LM, Meredith AL, Ghanim B, Klepetko W, Kwapiszewska G, Weir EK, Olschewski H, Olschewski A.

Eur Respir J. 2016 Oct;48(4):1127-1136. doi: 10.1183/13993003.01814-2015. Epub 2016 Aug 18.


Social acceptability of phytoremediation: The role of risk and values.

Weir E, Doty S.

Int J Phytoremediation. 2016 Oct 2;18(10):1029-36. doi: 10.1080/15226514.2016.1183571.


The Critical Role of Pulmonary Arterial Compliance in Pulmonary Hypertension.

Thenappan T, Prins KW, Pritzker MR, Scandurra J, Volmers K, Weir EK.

Ann Am Thorac Soc. 2016 Feb;13(2):276-84. doi: 10.1513/AnnalsATS.201509-599FR. Review.


Is cardiac resynchronization therapy for right ventricular failure in pulmonary arterial hypertension of benefit?

Rasmussen JT, Thenappan T, Benditt DG, Weir EK, Pritzker MR.

Pulm Circ. 2014 Dec;4(4):552-9. doi: 10.1086/678470. Review.


Deprescribing for older patients.

Frank C, Weir E.

CMAJ. 2014 Dec 9;186(18):1369-76. doi: 10.1503/cmaj.131873. Epub 2014 Sep 2. Review. No abstract available.


Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.

Hong Z, Cabrera JA, Mahapatra S, Kutty S, Weir EK, Archer SL.

J Mol Med (Berl). 2014 Sep;92(9):995-1007. doi: 10.1007/s00109-014-1162-1. Epub 2014 Jun 8.


Redox regulation of ion channels in the pulmonary circulation.

Olschewski A, Weir EK.

Antioxid Redox Signal. 2015 Feb 20;22(6):465-85. doi: 10.1089/ars.2014.5899. Epub 2014 Jun 30. Review.


Improving collaboration between public health and family health teams in Ontario.

Green ME, Weir E, Hogg W, Etches V, Moore K, Hunter D, Birtwhistle R.

Healthc Policy. 2013 Feb;8(3):e93-104.


Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.

Hong Z, Kutty S, Toth PT, Marsboom G, Hammel JM, Chamberlain C, Ryan JJ, Zhang HJ, Sharp WW, Morrow E, Trivedi K, Weir EK, Archer SL.

Circ Res. 2013 Mar 1;112(5):802-15. doi: 10.1161/CIRCRESAHA.111.300285. Epub 2013 Jan 18.


Atypical prediagnosis Epstein-Barr virus serology restricted to EBV-positive Hodgkin lymphoma.

Levin LI, Chang ET, Ambinder RF, Lennette ET, Rubertone MV, Mann RB, Borowitz M, Weir EG, Abbondanzo SL, Mueller NE.

Blood. 2012 Nov 1;120(18):3750-5. doi: 10.1182/blood-2011-12-390823. Epub 2012 Sep 12.


Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries.

Nagaraj C, Tang B, Bálint Z, Wygrecka M, Hrzenjak A, Kwapiszewska G, Stacher E, Lindenmann J, Weir EK, Olschewski H, Olschewski A.

Eur Respir J. 2013 Jan;41(1):85-95. doi: 10.1183/09031936.00211811. Epub 2012 Apr 20.


Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.

Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL.

Circ Res. 2012 May 25;110(11):1484-97. doi: 10.1161/CIRCRESAHA.111.263848. Epub 2012 Apr 17.


Left ventricular failure produces profound lung remodeling and pulmonary hypertension in mice: heart failure causes severe lung disease.

Chen Y, Guo H, Xu D, Xu X, Wang H, Hu X, Lu Z, Kwak D, Xu Y, Gunther R, Huo Y, Weir EK.

Hypertension. 2012 Jun;59(6):1170-8. doi: 10.1161/HYPERTENSIONAHA.111.186072. Epub 2012 Apr 16.


Characterization of blaCMY-2 plasmids in Salmonella and Escherichia coli isolates from food animals in Canada.

Martin LC, Weir EK, Poppe C, Reid-Smith RJ, Boerlin P.

Appl Environ Microbiol. 2012 Feb;78(4):1285-7. doi: 10.1128/AEM.06498-11. Epub 2011 Dec 9.


Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase.

Xu D, Guo H, Xu X, Lu Z, Fassett J, Hu X, Xu Y, Tang Q, Hu D, Somani A, Geurts AM, Ostertag E, Bache RJ, Weir EK, Chen Y.

Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5.


Intergenerational Ambivalence: Aging Mothers Whose Adult Daughters are Mentally Ill.

Ingersoll-Dayton B, Dunkle RE, Chadiha L, Lawrence-Jacobson A, Li L, Weir E, Satorius J.

Fam Soc. 2011;92(1):114-119.


A Canadian framework for applying the precautionary principle to public health issues.

Weir E, Schabas R, Wilson K, Mackie C.

Can J Public Health. 2010 Sep-Oct;101(5):396-8.


Increase in GLUT1 in smooth muscle alters vascular contractility and increases inflammation in response to vascular injury.

Adhikari N, Basi DL, Carlson M, Mariash A, Hong Z, Lehman U, Mullegama S, Weir EK, Hall JL.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):86-94. doi: 10.1161/ATVBAHA.110.215004. Epub 2010 Oct 14.


Severe human rhinovirus outbreak associated with fatalities in a long-term care facility in Ontario, Canada.

Longtin J, Winter AL, Heng D, Marchand-Austin A, Eshaghi A, Patel S, Jamieson F, Weir E, Low DE, Gubbay JB.

J Am Geriatr Soc. 2010 Oct;58(10):2036-8. doi: 10.1111/j.1532-5415.2010.03091.x. No abstract available.


Redesign of internal-medicine teaching.

Weir EK.

N Engl J Med. 2010 Aug 5;363(6):593; author reply 594-5. doi: 10.1056/NEJMc1005271. No abstract available.


The role of redox changes in oxygen sensing.

Weir EK, Archer SL.

Respir Physiol Neurobiol. 2010 Dec 31;174(3):182-91. doi: 10.1016/j.resp.2010.08.015. Epub 2010 Aug 27. Review.


Superoxide dismutase: master and commander?

Weir EK, Hong Z, Chen Y.

Eur Respir J. 2010 Aug;36(2):234-6. doi: 10.1183/09031936.00062510. No abstract available.


Legionellosis: Why should I test and report?

Marrie TJ, Garay JR, Weir E.

CMAJ. 2010 Oct 5;182(14):1538-42. doi: 10.1503/cmaj.082030. Epub 2010 Jul 5. No abstract available.


Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies.

Archer SL, Weir EK, Wilkins MR.

Circulation. 2010 May 11;121(18):2045-66. doi: 10.1161/CIRCULATIONAHA.108.847707. Review. No abstract available.


Period four metal nanoparticles on the inhibition of biofouling.

Chapman J, Weir E, Regan F.

Colloids Surf B Biointerfaces. 2010 Jul 1;78(2):208-16. doi: 10.1016/j.colsurfb.2010.03.002. Epub 2010 Mar 9.


The role of ion channels in hypoxic pulmonary vasoconstriction.

Weir EK, Cabrera JA, Mahapatra S, Peterson DA, Hong Z.

Adv Exp Med Biol. 2010;661:3-14. doi: 10.1007/978-1-60761-500-2_1. Review.


Cellular and molecular basis of pulmonary arterial hypertension.

Morrell NW, Adnot S, Archer SL, Dupuis J, Jones PL, MacLean MR, McMurtry IF, Stenmark KR, Thistlethwaite PA, Weissmann N, Yuan JX, Weir EK.

J Am Coll Cardiol. 2009 Jun 30;54(1 Suppl):S20-31. doi: 10.1016/j.jacc.2009.04.018. Review.


Lymphoma, leukemia, and pleiocytosis in cerebrospinal fluid: is accurate cytopathologic diagnosis possible based on morphology alone?

Wu JM, Georgy MF, Burroughs FH, Weir EG, Rosenthal DL, Ali SZ.

Diagn Cytopathol. 2009 Nov;37(11):820-4. doi: 10.1002/dc.21110.


Assessment of graft patency during coronary artery bypass graft surgery: mitigating the risk.

Ward HB, Kelly RF, Weir EK.

JACC Cardiovasc Imaging. 2009 May;2(5):613-5. doi: 10.1016/j.jcmg.2009.01.009. No abstract available.


Applying the balanced scorecard to local public health performance measurement: deliberations and decisions.

Weir E, d'Entremont N, Stalker S, Kurji K, Robinson V.

BMC Public Health. 2009 May 8;9:127. doi: 10.1186/1471-2458-9-127.


Planning a coordinated local health care system response to a pandemic using an accelerated Delphi technique: phase 1.

Stalker SA, Weir E, Vessel SL, Mikail J.

Can J Public Health. 2009 Jan-Feb;100(1):65-9.


Subinhibitory concentrations of tetracycline affect virulence gene expression in a multi-resistant Salmonella enterica subsp. enterica serovar Typhimurium DT104.

Weir EK, Martin LC, Poppe C, Coombes BK, Boerlin P.

Microbes Infect. 2008 Jul;10(8):901-7. doi: 10.1016/j.micinf.2008.05.005. Epub 2008 Jun 18.


Mechanisms of oxygen sensing: a key to therapy of pulmonary hypertension and patent ductus arteriosus.

Weir EK, Obreztchikova M, Vargese A, Cabrera JA, Peterson DA, Hong Z.

Br J Pharmacol. 2008 Oct;155(3):300-7. doi: 10.1038/bjp.2008.291. Epub 2008 Jul 21. Review.

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