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Identification of a T follicular helper cell subset that drives anaphylactic IgE.

Gowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC.

Science. 2019 Aug 30;365(6456). pii: eaaw6433. doi: 10.1126/science.aaw6433. Epub 2019 Aug 1.


Specific sequences of infectious challenge lead to secondary hemophagocytic lymphohistiocytosis-like disease in mice.

Wang A, Pope SD, Weinstein JS, Yu S, Zhang C, Booth CJ, Medzhitov R.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2200-2209. doi: 10.1073/pnas.1820704116. Epub 2019 Jan 23.


Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection.

Xin G, Zander R, Schauder DM, Chen Y, Weinstein JS, Drobyski WR, Tarakanova V, Craft J, Cui W.

Nat Commun. 2018 Nov 28;9(1):5037. doi: 10.1038/s41467-018-07492-4.


Correction: STAT4 and T-bet control follicular helper T cell development in viral infections.

Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J.

J Exp Med. 2018 Mar 5;215(3):999. doi: 10.1084/jem.2017045702062018c. Epub 2018 Feb 13. No abstract available.


STAT4 and T-bet control follicular helper T cell development in viral infections.

Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J.

J Exp Med. 2018 Jan 2;215(1):337-355. doi: 10.1084/jem.20170457. Epub 2017 Dec 6. Erratum in: J Exp Med. 2018 Feb 13;:.


Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response.

Laidlaw BJ, Lu Y, Amezquita RA, Weinstein JS, Vander Heiden JA, Gupta NT, Kleinstein SH, Kaech SM, Craft J.

Sci Immunol. 2017 Oct 20;2(16). pii: eaan4767. doi: 10.1126/sciimmunol.aan4767.


Dispositional negativity in the wild: Social environment governs momentary emotional experience.

Shackman AJ, Weinstein JS, Hudja SN, Bloomer CD, Barstead MG, Fox AS, Lemay EP.

Emotion. 2018 Aug;18(5):707-724. doi: 10.1037/emo0000339. Epub 2017 Jun 12.


Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells.

Bosurgi L, Cao YG, Cabeza-Cabrerizo M, Tucci A, Hughes LD, Kong Y, Weinstein JS, Licona-Limon P, Schmid ET, Pelorosso F, Gagliani N, Craft JE, Flavell RA, Ghosh S, Rothlin CV.

Science. 2017 Jun 9;356(6342):1072-1076. doi: 10.1126/science.aai8132. Epub 2017 May 11.


TFH cells progressively differentiate to regulate the germinal center response.

Weinstein JS, Herman EI, Lainez B, Licona-Limón P, Esplugues E, Flavell R, Craft J.

Nat Immunol. 2016 Oct;17(10):1197-1205. doi: 10.1038/ni.3554. Epub 2016 Aug 29.


The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.

Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, Burchard EG, Torgerson DG, Ghosh S, Rothlin CV.

Science. 2016 Apr 1;352(6281):99-103. doi: 10.1126/science.aaf1358.


A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control.

Xin G, Schauder DM, Lainez B, Weinstein JS, Dai Z, Chen Y, Esplugues E, Wen R, Wang D, Parish IA, Zajac AJ, Craft J, Cui W.

Cell Rep. 2015 Nov 10;13(6):1118-1124. doi: 10.1016/j.celrep.2015.09.069. Epub 2015 Oct 29.


IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells.

Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A.

J Immunol. 2015 Dec 1;195(11):5251-60. doi: 10.4049/jimmunol.1500777. Epub 2015 Oct 30.


Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes.

Weinstein JS, Lezon-Geyda K, Maksimova Y, Craft S, Zhang Y, Su M, Schulz VP, Craft J, Gallagher PG.

Blood. 2014 Dec 11;124(25):3719-29. doi: 10.1182/blood-2014-06-582700. Epub 2014 Oct 20.


Dynamic signaling by T follicular helper cells during germinal center B cell selection.

Shulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft JE, Nussenzweig MC.

Science. 2014 Aug 29;345(6200):1058-62. doi: 10.1126/science.1257861.


B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen.

Weinstein JS, Bertino SA, Hernandez SG, Poholek AC, Teplitzky TB, Nowyhed HN, Craft J.

J Immunol. 2014 Apr 1;192(7):3166-79. doi: 10.4049/jimmunol.1302617. Epub 2014 Mar 7.


CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity.

Kumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A.

Immunity. 2013 Oct 17;39(4):733-43. doi: 10.1016/j.immuni.2013.08.029. Epub 2013 Sep 26.


Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells.

Gao Y, Nish SA, Jiang R, Hou L, Licona-Limón P, Weinstein JS, Zhao H, Medzhitov R.

Immunity. 2013 Oct 17;39(4):722-32. doi: 10.1016/j.immuni.2013.08.028. Epub 2013 Sep 26.


Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells.

Weinstein JS, Delano MJ, Xu Y, Kelly-Scumpia KM, Nacionales DC, Li Y, Lee PY, Scumpia PO, Yang L, Sobel E, Moldawer LL, Reeves WH.

J Immunol. 2013 Apr 15;190(8):3916-27. doi: 10.4049/jimmunol.1201880. Epub 2013 Mar 18.


T cells that promote B-Cell maturation in systemic autoimmunity.

Weinstein JS, Hernandez SG, Craft J.

Immunol Rev. 2012 May;247(1):160-71. doi: 10.1111/j.1600-065X.2012.01122.x. Review.


An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells.

Cui W, Liu Y, Weinstein JS, Craft J, Kaech SM.

Immunity. 2011 Nov 23;35(5):792-805. doi: 10.1016/j.immuni.2011.09.017.


Pathogenic role of B cells in the development of diffuse alveolar hemorrhage induced by pristane.

Barker TT, Lee PY, Kelly-Scumpia KM, Weinstein JS, Nacionales DC, Kumagai Y, Akira S, Croker BP, Sobel ES, Reeves WH, Satoh M.

Lab Invest. 2011 Oct;91(10):1540-50. doi: 10.1038/labinvest.2011.108. Epub 2011 Aug 1.


B cells enhance early innate immune responses during bacterial sepsis.

Kelly-Scumpia KM, Scumpia PO, Weinstein JS, Delano MJ, Cuenca AG, Nacionales DC, Wynn JL, Lee PY, Kumagai Y, Efron PA, Akira S, Wasserfall C, Atkinson MA, Moldawer LL.

J Exp Med. 2011 Aug 1;208(8):1673-82. doi: 10.1084/jem.20101715. Epub 2011 Jul 11.


In vivo regulation of Bcl6 and T follicular helper cell development.

Poholek AC, Hansen K, Hernandez SG, Eto D, Chandele A, Weinstein JS, Dong X, Odegard JM, Kaech SM, Dent AL, Crotty S, Craft J.

J Immunol. 2010 Jul 1;185(1):313-26. doi: 10.4049/jimmunol.0904023. Epub 2010 Jun 2.


Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling.

Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, Al-Quran S, Bovio I, Akira S, Kumagai Y, Moldawer LL.

J Immunol. 2010 Mar 1;184(5):2247-51. doi: 10.4049/jimmunol.0903652. Epub 2010 Feb 3.


Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10.

Kelly-Scumpia KM, Scumpia PO, Delano MJ, Weinstein JS, Cuenca AG, Wynn JL, Moldawer LL.

J Exp Med. 2010 Feb 15;207(2):319-26. doi: 10.1084/jem.20091959. Epub 2010 Jan 13.


Type I interferon modulates monocyte recruitment and maturation in chronic inflammation.

Lee PY, Li Y, Kumagai Y, Xu Y, Weinstein JS, Kellner ES, Nacionales DC, Butfiloski EJ, van Rooijen N, Akira S, Sobel ES, Satoh M, Reeves WH.

Am J Pathol. 2009 Nov;175(5):2023-33. doi: 10.2353/ajpath.2009.090328. Epub 2009 Oct 1.


Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a review.

Weinstein JS, Varallyay CG, Dosa E, Gahramanov S, Hamilton B, Rooney WD, Muldoon LL, Neuwelt EA.

J Cereb Blood Flow Metab. 2010 Jan;30(1):15-35. doi: 10.1038/jcbfm.2009.192. Epub 2009 Sep 16. Review.


Induction of autoimmunity by pristane and other naturally occurring hydrocarbons.

Reeves WH, Lee PY, Weinstein JS, Satoh M, Lu L.

Trends Immunol. 2009 Sep;30(9):455-64. doi: 10.1016/ Epub 2009 Aug 19. Review.


The safety and effectiveness of a dural sealant system for use with nonautologous duraplasty materials.

Weinstein JS, Liu KC, Delashaw JB Jr, Burchiel KJ, van Loveren HR, Vale FL, Agazzi S, Greenberg MS, Smith DA, Tew J Jr.

J Neurosurg. 2010 Feb;112(2):428-33. doi: 10.3171/2009.6.JNS081540.


Dandy'S disc.

Weinstein JS, Burchiel KJ.

Neurosurgery. 2009 Jul;65(1):201-5; discussion 205. doi: 10.1227/01.NEU.0000346267.60064.3D.


B cell proliferation, somatic hypermutation, class switch recombination, and autoantibody production in ectopic lymphoid tissue in murine lupus.

Nacionales DC, Weinstein JS, Yan XJ, Albesiano E, Lee PY, Kelly-Scumpia KM, Lyons R, Satoh M, Chiorazzi N, Reeves WH.

J Immunol. 2009 Apr 1;182(7):4226-36. doi: 10.4049/jimmunol.0800771.


Colocalization of antigen-specific B and T cells within ectopic lymphoid tissue following immunization with exogenous antigen.

Weinstein JS, Nacionales DC, Lee PY, Kelly-Scumpia KM, Yan XJ, Scumpia PO, Vale-Cruz DS, Sobel E, Satoh M, Chiorazzi N, Reeves WH.

J Immunol. 2008 Sep 1;181(5):3259-67.


A novel type I IFN-producing cell subset in murine lupus.

Lee PY, Weinstein JS, Nacionales DC, Scumpia PO, Li Y, Butfiloski E, van Rooijen N, Moldawer L, Satoh M, Reeves WH.

J Immunol. 2008 Apr 1;180(7):5101-8.


Deficiency of the type I interferon receptor protects mice from experimental lupus.

Nacionales DC, Kelly-Scumpia KM, Lee PY, Weinstein JS, Lyons R, Sobel E, Satoh M, Reeves WH.

Arthritis Rheum. 2007 Nov;56(11):3770-83.


In vivo adjuvant activity of the RNA component of the Sm/RNP lupus autoantigen.

Kelly-Scumpia KM, Nacionales DC, Scumpia PO, Weinstein JS, Narain S, Moldawer LL, Satoh M, Reeves WH.

Arthritis Rheum. 2007 Oct;56(10):3379-86.


Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis.

Scumpia PO, Delano MJ, Kelly-Scumpia KM, Weinstein JS, Wynn JL, Winfield RD, Xia C, Chung CS, Ayala A, Atkinson MA, Reeves WH, Clare-Salzler MJ, Moldawer LL.

Blood. 2007 Nov 15;110(10):3673-81. Epub 2007 Aug 9.


MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis.

Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, Kelly-Scumpia KM, O'Malley KA, Wynn JL, Antonenko S, Al-Quran SZ, Swan R, Chung CS, Atkinson MA, Ramphal R, Gabrilovich DI, Reeves WH, Ayala A, Phillips J, Laface D, Heyworth PG, Clare-Salzler M, Moldawer LL.

J Exp Med. 2007 Jun 11;204(6):1463-74. Epub 2007 Jun 4.


Self-inflicted nail-gun injury with 12 cranial penetrations and associated cerebral trauma. Case report and review of the literature.

Litvack ZN, Hunt MA, Weinstein JS, West GA.

J Neurosurg. 2006 May;104(5):828-34. Review.


Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane).

Nacionales DC, Kelly KM, Lee PY, Zhuang H, Li Y, Weinstein JS, Sobel E, Kuroda Y, Akaogi J, Satoh M, Reeves WH.

Am J Pathol. 2006 Apr;168(4):1227-40.


Stress affects dopaminergic signaling pathways in Drosophila melanogaster.

Neckameyer WS, Weinstein JS.

Stress. 2005 Jun;8(2):117-31.


Two-stage total hepatectomy and liver transplantation for acute deterioration of chronic liver disease: a new bridge to transplantation.

Guirl MJ, Weinstein JS, Goldstein RM, Levy MF, Klintmalm GB.

Liver Transpl. 2004 Apr;10(4):564-70.


Pseudohypocalcemia after magnetic resonance imaging with gadolinium in patients with cirrhosis.

Kefalas CH, Murray NG, Aguanno JJ, Dockery WD, Weinstein JS, Anderson K, Klintmalm GB.

Liver Transpl. 2004 Jan;10(1):136-40.


The changing clinical presentation of recurrent primary biliary cirrhosis after liver transplantation.

Sanchez EQ, Levy MF, Goldstein RM, Fasola CG, Tillery GW, Netto GJ, Watkins DL, Weinstein JS, Murray NG, Byers D, Christensen LL, Klintmalm GB.

Transplantation. 2003 Dec 15;76(11):1583-8.


Pretransplant MELD score as a predictor of outcome after liver transplantation for chronic hepatitis C.

Onaca NN, Levy MF, Netto GJ, Thomas MJ, Sanchez EQ, Chinnakotla S, Fasola CG, Weinstein JS, Murray N, Goldstein RM, Klintmalm GB.

Am J Transplant. 2003 May;3(5):626-30.


A correlation between the pretransplantation MELD score and mortality in the first two years after liver transplantation.

Onaca NN, Levy MF, Sanchez EQ, Chinnakotla S, Fasola CG, Thomas MJ, Weinstein JS, Murray NG, Goldstein RM, Klintmalm GB.

Liver Transpl. 2003 Feb;9(2):117-23.


Epidemiology and natural history of hepatitis C infections in liver transplant recipients.

Weinstein JS, Poterucha JJ, Zein N, Wiesner RH, Persing DH, Rakela J.

J Hepatol. 1995;22(1 Suppl):154-9.


Ultrasonic angioplasty in totally occluded peripheral arteries. Initial clinical, histological, and angiographic results.

Rosenschein U, Rozenszajn LA, Kraus L, Marboe CC, Watkins JF, Rose EA, David D, Cannon PJ, Weinstein JS.

Circulation. 1991 Jun;83(6):1976-86.


Salvage of branch vessels during bifurcation lesion angioplasty: acute and long-term follow-up.

Weinstein JS, Baim DS, Sipperly ME, McCabe CH, Lorell BH.

Cathet Cardiovasc Diagn. 1991 Jan;22(1):1-6.


Differences in alpha-adrenergic responsiveness between human internal mammary arteries and saphenous veins.

Weinstein JS, Grossman W, Weintraub RM, Thurer RL, Johnson RG, Morgan KG.

Circulation. 1989 Jun;79(6):1264-70.


Progressive improvement in pulmonary vascular resistance after percutaneous mitral valvuloplasty.

Levine MJ, Weinstein JS, Diver DJ, Berman AD, Wyman RM, Cunningham MJ, Safian RD, Grossman W, McKay RG.

Circulation. 1989 May;79(5):1061-7.


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