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Items: 1 to 50 of 514

1.

Benzophenones and biflavonoids from Garcinia livingstonei fruits.

Yang H, Figueroa M, To S, Baggett S, Jiang B, Basile MJ, Weinstein IB, Kennelly EJ.

J Agric Food Chem. 2010 Apr 28;58(8):4749-55. doi: 10.1021/jf9046094.

PMID:
20345100
2.

Stat3 orchestrates tumor development and progression: the Achilles' heel of head and neck cancers?

Masuda M, Wakasaki T, Suzui M, Toh S, Joe AK, Weinstein IB.

Curr Cancer Drug Targets. 2010 Feb;10(1):117-26. Review.

PMID:
20088788
3.

(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.

Adachi S, Shimizu M, Shirakami Y, Yamauchi J, Natsume H, Matsushima-Nishiwaki R, To S, Weinstein IB, Moriwaki H, Kozawa O.

Carcinogenesis. 2009 Sep;30(9):1544-52. doi: 10.1093/carcin/bgp166. Epub 2009 Jul 3.

PMID:
19578043
4.

Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src.

Cen B, Li H, Weinstein IB.

J Biol Chem. 2009 Feb 20;284(8):5265-76. doi: 10.1074/jbc.M804531200. Epub 2008 Dec 27.

5.

HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells.

Wang L, Li H, Zhang Y, Santella RM, Weinstein IB.

Int J Cancer. 2009 Apr 1;124(7):1526-34. doi: 10.1002/ijc.24072.

6.

The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage.

Li H, Balajee AS, Su T, Cen B, Hei TK, Weinstein IB.

J Cell Biol. 2008 Oct 20;183(2):253-65. doi: 10.1083/jcb.200711150. Epub 2008 Oct 13.

7.

The history of Cancer Research: introducing an AACR Centennial series.

Weinstein IB, Case K.

Cancer Res. 2008 Sep 1;68(17):6861-2. doi: 10.1158/0008-5472.CAN-08-2827. No abstract available.

8.

Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.

Cen B, Deguchi A, Weinstein IB.

Cancer Res. 2008 Jul 1;68(13):5355-62. doi: 10.1158/0008-5472.CAN-07-6869.

9.

(-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.

Adachi S, Nagao T, To S, Joe AK, Shimizu M, Matsushima-Nishiwaki R, Kozawa O, Moriwaki H, Maxfield FR, Weinstein IB.

Carcinogenesis. 2008 Oct;29(10):1986-93. doi: 10.1093/carcin/bgn128. Epub 2008 Jun 26.

10.

Oncogene addiction.

Weinstein IB, Joe A.

Cancer Res. 2008 May 1;68(9):3077-80; discussion 3080. doi: 10.1158/0008-5472.CAN-07-3293. Review.

11.

Cytotoxic chalcones and antioxidants from the fruits of a Syzygium samarangense (Wax Jambu).

Simirgiotis MJ, Adachi S, To S, Yang H, Reynertson KA, Basile MJ, Gil RR, Weinstein IB, Kennelly EJ.

Food Chem. 2008 Mar 15;107(2):813-819.

12.

TREK-1 is a novel molecular target in prostate cancer.

Voloshyna I, Besana A, Castillo M, Matos T, Weinstein IB, Mansukhani M, Robinson RB, Cordon-Cardo C, Feinmark SJ.

Cancer Res. 2008 Feb 15;68(4):1197-203. doi: 10.1158/0008-5472.CAN-07-5163.

13.

EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells.

Shimizu M, Shirakami Y, Sakai H, Tatebe H, Nakagawa T, Hara Y, Weinstein IB, Moriwaki H.

Cancer Lett. 2008 Apr 8;262(1):10-8. doi: 10.1016/j.canlet.2007.11.026. Epub 2007 Dec 31.

PMID:
18164805
14.

Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.

Soh JW, Kazi JU, Li H, Thompson WJ, Weinstein IB.

Mol Carcinog. 2008 Jul;47(7):519-25. doi: 10.1002/mc.20409.

PMID:
18163459
15.

Activated checkpoint kinase 2 expression and risk for oral squamous cell carcinoma.

Yoon AJ, Shen J, Santella RM, Zegarelli DJ, Chen R, Weinstein IB.

Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2768-72.

16.

The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways.

Einbond LS, Su T, Wu HA, Friedman R, Wang X, Ramirez A, Kronenberg F, Weinstein IB.

Int J Cancer. 2007 Nov 1;121(9):2073-83.

17.

The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells.

Adachi S, Nagao T, Ingolfsson HI, Maxfield FR, Andersen OS, Kopelovich L, Weinstein IB.

Cancer Res. 2007 Jul 1;67(13):6493-501.

18.

Synergistic effects of RXR alpha and PPAR gamma ligands to inhibit growth in human colon cancer cells--phosphorylated RXR alpha is a critical target for colon cancer management.

Yamazaki K, Shimizu M, Okuno M, Matsushima-Nishiwaki R, Kanemura N, Araki H, Tsurumi H, Kojima S, Weinstein IB, Moriwaki H.

Gut. 2007 Nov;56(11):1557-63. Epub 2007 Jun 29.

19.

Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells.

Wang L, Zhang Y, Li H, Xu Z, Santella RM, Weinstein IB.

Cancer Res. 2007 May 15;67(10):4700-8.

20.

Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth.

Einbond LS, Su T, Wu HA, Friedman R, Wang X, Jiang B, Hagan T, Kennelly EJ, Kronenberg F, Weinstein IB.

Anticancer Res. 2007 Mar-Apr;27(2):697-712.

21.

Dip1 inhibits growth and gene transcription in MCF-7 breast cancer cells.

Su T, Deguchi A, Yao Y, Luo J, Weinstein IB.

J Exp Ther Oncol. 2007;6(2):117-27.

PMID:
17407970
22.

Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma.

Masuda M, Ruan HY, Ito A, Nakashima T, Toh S, Wakasaki T, Yasumatsu R, Kutratomi Y, Komune S, Weinstein IB.

Oral Oncol. 2007 Sep;43(8):785-90. Epub 2006 Dec 13.

PMID:
17169602
23.
24.

Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells.

Einbond LS, Shimizu M, Nuntanakorn P, Seter C, Cheng R, Jiang B, Kronenberg F, Kennelly EJ, Weinstein IB.

Planta Med. 2006 Oct;72(13):1200-6. Epub 2006 Sep 20. Erratum in: Planta Med. 2007 Feb;73(2):189.

PMID:
16988912
25.

Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora).

Reynertson KA, Wallace AM, Adachi S, Gil RR, Yang H, Basile MJ, D'Armiento J, Weinstein IB, Kennelly EJ.

J Nat Prod. 2006 Aug;69(8):1228-30.

PMID:
16933884
26.

Non-steroidal anti-inflammatory drugs have bacteriostatic and bactericidal activity against Helicobacter pylori.

Shirin H, Moss SF, Kancherla S, Kancherla K, Holt PR, Weinstein IB, Sordillo EM.

J Gastroenterol Hepatol. 2006 Sep;21(9):1388-93.

PMID:
16911681
27.

Antisense to cyclin D1 inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells: implication of tumor vascularization.

Yasui M, Yamamoto H, Ngan CY, Damdinsuren B, Sugita Y, Fukunaga H, Gu J, Maeda M, Takemasa I, Ikeda M, Fujio Y, Sekimoto M, Matsuura N, Weinstein IB, Monden M.

Clin Cancer Res. 2006 Aug 1;12(15):4720-9.

28.

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy.

Weinstein IB, Joe AK.

Nat Clin Pract Oncol. 2006 Aug;3(8):448-57. Review.

PMID:
16894390
29.

Sulindac sulfide and exisulind inhibit expression of the estrogen and progesterone receptors in human breast cancer cells.

Lim JT, Joe AK, Suzui M, Shimizu M, Masuda M, Weinstein IB.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3478-84.

30.

Polyphenolic constituents of Actaea racemosa.

Nuntanakorn P, Jiang B, Einbond LS, Yang H, Kronenberg F, Weinstein IB, Kennelly EJ.

J Nat Prod. 2006 Mar;69(3):314-8.

PMID:
16562825
31.

The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization.

Xiao D, Deguchi A, Gundersen GG, Oehlen B, Arnold L, Weinstein IB.

Mol Cancer Ther. 2006 Jan;5(1):60-7.

32.

EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.

Shimizu M, Deguchi A, Joe AK, Mckoy JF, Moriwaki H, Weinstein IB.

J Exp Ther Oncol. 2005;5(1):69-78.

PMID:
16416603
33.

Effects of a novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), on growth, apoptosis, gene expression, and chemosensitivity in head and neck squamous cell carcinoma cell lines.

Ruan HY, Masuda M, Ito A, Umezawa K, Nakashima T, Yasumatsu R, Kuratomi Y, Yamamoto T, Weinstein IB, Komune S.

Head Neck. 2006 Feb;28(2):158-65.

PMID:
16355386
34.

Antioxidant and cytotoxic isoprenylated coumarins from Mammea americana.

Yang H, Protiva P, Gil RR, Jiang B, Baggett S, Basile MJ, Reynertson KA, Weinstein IB, Kennelly EJ.

Planta Med. 2005 Sep;71(9):852-60.

PMID:
16206041
35.

Hint1 is a haplo-insufficient tumor suppressor in mice.

Li H, Zhang Y, Su T, Santella RM, Weinstein IB.

Oncogene. 2006 Feb 2;25(5):713-21.

PMID:
16186798
36.

Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells.

Xiao D, Pinto JT, Gundersen GG, Weinstein IB.

Mol Cancer Ther. 2005 Sep;4(9):1388-98.

37.

Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.

Deguchi A, Xing SW, Shureiqi I, Yang P, Newman RA, Lippman SM, Feinmark SJ, Oehlen B, Weinstein IB.

Cancer Res. 2005 Sep 15;65(18):8442-7.

38.

EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.

Shimizu M, Deguchi A, Hara Y, Moriwaki H, Weinstein IB.

Biochem Biophys Res Commun. 2005 Sep 2;334(3):947-53.

PMID:
16053920
39.

Modulation of signal transduction by tea catechins and related phytochemicals.

Shimizu M, Weinstein IB.

Mutat Res. 2005 Dec 11;591(1-2):147-60. Epub 2005 Jun 29. Review.

PMID:
15992833
41.

Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells.

Lim JT, Mansukhani M, Weinstein IB.

Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5156-61. Epub 2005 Mar 24. Erratum in: Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8786-7.

42.

Bioactive benzophenones from Garcinia xanthochymus fruits.

Baggett S, Protiva P, Mazzola EP, Yang H, Ressler ET, Basile MJ, Weinstein IB, Kennelly EJ.

J Nat Prod. 2005 Mar;68(3):354-60.

PMID:
15787435
43.
44.

Synergistic effects of acyclic retinoid and OSI-461 on growth inhibition and gene expression in human hepatoma cells.

Shimizu M, Suzui M, Deguchi A, Lim JT, Xiao D, Hayes JH, Papadopoulos KP, Weinstein IB.

Clin Cancer Res. 2004 Oct 1;10(19):6710-21.

45.

Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis.

Jiang XH, Tu SP, Cui JT, Lin MC, Xia HH, Wong WM, Chan AO, Yuen MF, Jiang SH, Lam SK, Kung HF, Soh JW, Weinstein IB, Wong BC.

Cancer Res. 2004 Aug 15;64(16):5787-94.

46.
47.

Acyclic retinoid activates retinoic acid receptor beta and induces transcriptional activation of p21(CIP1) in HepG2 human hepatoma cells.

Suzui M, Shimizu M, Masuda M, Lim JT, Yoshimi N, Weinstein IB.

Mol Cancer Ther. 2004 Mar;3(3):309-16.

48.

Mast cells provide a "HINT" to the function of an exotic nucleotide.

Weinstein IB, Li H.

Immunity. 2004 Feb;20(2):119-20. Review.

49.
50.

Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells.

Einbond LS, Shimizu M, Xiao D, Nuntanakorn P, Lim JT, Suzui M, Seter C, Pertel T, Kennelly EJ, Kronenberg F, Weinstein IB.

Breast Cancer Res Treat. 2004 Feb;83(3):221-31.

PMID:
14758092

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