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Items: 1 to 50 of 166

1.

Genomic clustering of fitness-affecting mutations favors the evolution of chromosomal instability.

Raynes Y, Weinreich DM.

Evol Appl. 2018 Oct 11;12(2):301-313. doi: 10.1111/eva.12717. eCollection 2019 Feb.

2.

Migration promotes mutator alleles in subdivided populations.

Raynes Y, Sniegowski PD, Weinreich DM.

Evolution. 2019 Mar;73(3):600-608. doi: 10.1111/evo.13681. Epub 2019 Jan 16.

PMID:
30632605
3.

Evolutionary constraints in fitness landscapes.

Ferretti L, Weinreich D, Tajima F, Achaz G.

Heredity (Edinb). 2018 Nov;121(5):466-481. doi: 10.1038/s41437-018-0110-1. Epub 2018 Jul 11.

PMID:
29993041
4.

The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography.

Weinreich DM, Lan Y, Jaffe J, Heckendorn RB.

J Stat Phys. 2018;172(1):208-225. doi: 10.1007/s10955-018-1975-3. Epub 2018 Feb 7.

5.

Patterns of musculoskeletal growth and dimensional changes associated with selection and developmental plasticity in domestic and wild strain turkeys.

Stover KK, Weinreich DM, Roberts TJ, Brainerd EL.

Ecol Evol. 2018 Feb 19;8(6):3229-3239. doi: 10.1002/ece3.3881. eCollection 2018 Mar.

6.

Sign of selection on mutation rate modifiers depends on population size.

Raynes Y, Wylie CS, Sniegowski PD, Weinreich DM.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3422-3427. doi: 10.1073/pnas.1715996115. Epub 2018 Mar 12.

7.
8.

Cavernous Nerve Injury by Radiation Therapy May Potentiate Erectile Dysfunction in Rats.

Mahmood J, Connors CQ, Alexander AA, Pavlovic R, Samanta S, Soman S, Matsui H, Sopko NA, Bivalacqua TJ, Weinreich D, Ho CY, Eley J, Sawant A, Jackson IL, Vujaskovic Z.

Int J Radiat Oncol Biol Phys. 2017 Nov 1;99(3):680-688. doi: 10.1016/j.ijrobp.2017.06.2449. Epub 2017 Jun 27. Erratum in: Int J Radiat Oncol Biol Phys. 2018 Apr 1;100(5):1304.

PMID:
29280463
9.

Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 β-Lactamase.

Knies JL, Cai F, Weinreich DM.

Mol Biol Evol. 2017 May 1;34(5):1040-1054. doi: 10.1093/molbev/msx053.

10.

Genetically Determined Variation in Lysis Time Variance in the Bacteriophage φX174.

Baker CW, Miller CR, Thaweethai T, Yuan J, Baker MH, Joyce P, Weinreich DM.

G3 (Bethesda). 2016 Apr 7;6(4):939-55. doi: 10.1534/g3.115.024075.

11.

Measuring epistasis in fitness landscapes: The correlation of fitness effects of mutations.

Ferretti L, Schmiegelt B, Weinreich D, Yamauchi A, Kobayashi Y, Tajima F, Achaz G.

J Theor Biol. 2016 May 7;396:132-43. doi: 10.1016/j.jtbi.2016.01.037. Epub 2016 Feb 20.

PMID:
26854875
12.

Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance.

Ogbunugafor CB, Wylie CS, Diakite I, Weinreich DM, Hartl DL.

PLoS Comput Biol. 2016 Jan 25;12(1):e1004710. doi: 10.1371/journal.pcbi.1004710. eCollection 2016 Jan.

13.

Quantitative Description of a Protein Fitness Landscape Based on Molecular Features.

Meini MR, Tomatis PE, Weinreich DM, Vila AJ.

Mol Biol Evol. 2015 Jul;32(7):1774-87. doi: 10.1093/molbev/msv059. Epub 2015 Mar 12.

14.

The evolution of phenotypic correlations and "developmental memory".

Watson RA, Wagner GP, Pavlicev M, Weinreich DM, Mills R.

Evolution. 2014 Apr;68(4):1124-38. doi: 10.1111/evo.12337. Epub 2014 Feb 1.

15.

Should evolutionary geneticists worry about higher-order epistasis?

Weinreich DM, Lan Y, Wylie CS, Heckendorn RB.

Curr Opin Genet Dev. 2013 Dec;23(6):700-7. doi: 10.1016/j.gde.2013.10.007. Epub 2013 Nov 27. Review.

16.
17.

Optic nerve inflammation and demyelination in a rodent model of nonarteritic anterior ischemic optic neuropathy.

Slater BJ, Vilson FL, Guo Y, Weinreich D, Hwang S, Bernstein SL.

Invest Ophthalmol Vis Sci. 2013 Dec 5;54(13):7952-61. doi: 10.1167/iovs.13-12064.

18.

PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema.

Nicholson JD, Puche AC, Guo Y, Weinreich D, Slater BJ, Bernstein SL.

PLoS One. 2012;7(12):e50021. doi: 10.1371/journal.pone.0050021. Epub 2012 Dec 20.

19.

Phase 1 study of trebananib (AMG 386), an angiogenesis targeting angiopoietin-1/2 antagonist, in Japanese patients with advanced solid tumors.

Doi T, Ohtsu A, Fuse N, Yoshino T, Tahara M, Shibayama K, Takubo T, Weinreich DM.

Cancer Chemother Pharmacol. 2013 Jan;71(1):227-35. doi: 10.1007/s00280-012-2000-1. Epub 2012 Nov 3.

20.

The interface of protein structure, protein biophysics, and molecular evolution.

Liberles DA, Teichmann SA, Bahar I, Bastolla U, Bloom J, Bornberg-Bauer E, Colwell LJ, de Koning AP, Dokholyan NV, Echave J, Elofsson A, Gerloff DL, Goldstein RA, Grahnen JA, Holder MT, Lakner C, Lartillot N, Lovell SC, Naylor G, Perica T, Pollock DD, Pupko T, Regan L, Roger A, Rubinstein N, Shakhnovich E, Sjölander K, Sunyaev S, Teufel AI, Thorne JL, Thornton JW, Weinreich DM, Whelan S.

Protein Sci. 2012 Jun;21(6):769-85. doi: 10.1002/pro.2071. Epub 2012 Apr 23. Review.

21.

Exposure-response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection.

Lu JF, Rasmussen E, Karlan BY, Vergote IB, Navale L, Kuchimanchi M, Melara R, Stepan DE, Weinreich DM, Sun YN.

Cancer Chemother Pharmacol. 2012 May;69(5):1135-44. doi: 10.1007/s00280-011-1787-5. Epub 2012 Jan 1.

22.

Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer.

Karlan BY, Oza AM, Richardson GE, Provencher DM, Hansen VL, Buck M, Chambers SK, Ghatage P, Pippitt CH Jr, Brown JV 3rd, Covens A, Nagarkar RV, Davy M, Leath CA 3rd, Nguyen H, Stepan DE, Weinreich DM, Tassoudji M, Sun YN, Vergote IB.

J Clin Oncol. 2012 Feb 1;30(4):362-71. doi: 10.1200/JCO.2010.34.3178. Epub 2011 Dec 19.

PMID:
22184370
23.

High-throughput identification of genetic interactions in HIV-1.

Weinreich DM.

Nat Genet. 2011 May;43(5):398-400. doi: 10.1038/ng.820. No abstract available.

PMID:
21522176
24.

Genome structure and the benefit of sex.

Watson RA, Weinreich DM, Wakeley J.

Evolution. 2011 Feb;65(2):523-36. doi: 10.1111/j.1558-5646.2010.01144.x. Epub 2010 Nov 5.

PMID:
21029076
25.

Causes and evolutionary significance of genetic convergence.

Christin PA, Weinreich DM, Besnard G.

Trends Genet. 2010 Sep;26(9):400-5. doi: 10.1016/j.tig.2010.06.005. Epub 2010 Aug 3.

PMID:
20685006
26.

The essential oil of Croton nepetaefolius selectively blocks histamine-augmented neuronal excitability in guinea-pig celiac ganglion.

Leal-Cardoso JH, Lahlou S, Weinreich D, Caldas Magalhães PJ.

J Pharm Pharmacol. 2010 Aug;62(8):1045-53. doi: 10.1111/j.2042-7158.2010.01121.x.

PMID:
20663039
27.

Geographic differences in sexual reassortment in RNA phage.

O'Keefe KJ, Silander OK, McCreery H, Weinreich DM, Wright KM, Chao L, Edwards SV, Remold SK, Turner PE.

Evolution. 2010 Oct;64(10):3010-23. doi: 10.1111/j.1558-5646.2010.01040.x. Epub 2010 Aug 19.

PMID:
20500219
28.

Three selections are better than one: clinal variation of thermal QTL from independent selection experiments in Drosophila.

Rand DM, Weinreich DM, Lerman D, Folk D, Gilchrist GW.

Evolution. 2010 Oct;64(10):2921-34. doi: 10.1111/j.1558-5646.2010.01039.x. Epub 2010 Aug 19.

29.

Excitation of primary afferent neurons by near-infrared light in vitro.

Katz EJ, Ilev IK, Krauthamer V, Kim DH, Weinreich D.

Neuroreport. 2010 Jun 23;21(9):662-6. doi: 10.1097/WNR.0b013e32833add3a.

PMID:
20495496
30.

Identification and inhibition of drug target interference in immunogenicity assays.

Zhong ZD, Dinnogen S, Hokom M, Ray C, Weinreich D, Swanson SJ, Chirmule N.

J Immunol Methods. 2010 Apr 15;355(1-2):21-8. doi: 10.1016/j.jim.2010.02.008. Epub 2010 Feb 24.

PMID:
20188106
31.

Influence of vagotomy on monosynaptic transmission at second-order nucleus tractus solitarius synapses.

Swartz JB, Weinreich D.

J Neurophysiol. 2009 Nov;102(5):2846-55. doi: 10.1152/jn.00168.2009. Epub 2009 Sep 2.

32.

Role of calcium in regulating primary sensory neuronal excitability.

Gover TD, Moreira TH, Weinreich D.

Handb Exp Pharmacol. 2009;(194):563-87. doi: 10.1007/978-3-540-79090-7_16. Review.

PMID:
19655118
33.

Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways.

Brown KM, Depristo MA, Weinreich DM, Hartl DL.

Mol Biol Evol. 2009 Nov;26(11):2455-62. doi: 10.1093/molbev/msp151. Epub 2009 Jul 14.

34.

Stepwise acquisition of pyrimethamine resistance in the malaria parasite.

Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12025-30. doi: 10.1073/pnas.0905922106. Epub 2009 Jul 8.

35.

Angiotensin II increases excitability and inhibits a transient potassium current in vagal primary sensory neurons.

Moreira TH, Cruz JS, Weinreich D.

Neuropeptides. 2009 Jun;43(3):193-9. doi: 10.1016/j.npep.2009.04.003. Epub 2009 May 9.

PMID:
19433335
36.

The identification of a caffeine-induced Ca2+ influx pathway in rat primary sensory neurons.

Daher JP, Gover TD, Moreira TH, Lopes VG, Weinreich D.

Mol Cell Biochem. 2009 Jul;327(1-2):15-9. doi: 10.1007/s11010-009-0036-2. Epub 2009 Feb 6.

37.

The path to student-centered teaching in gerontology and geriatrics.

Weinreich DM.

Gerontol Geriatr Educ. 2008;29(3):210-24. doi: 10.1080/07399330802359435.

PMID:
19042500
38.

Collaborating, teaching and learning in a cyberspace community: a virtual AGE experience.

Tompkins CJ, Weinreich DM.

J Gerontol Soc Work. 2007;50(1-2):119-34.

PMID:
18032303
39.

Electrophysiological properties and chemosensitivity of acutely dissociated trigeminal somata innervating the cornea.

Veiga Moreira TH, Gover TD, Weinreich D.

Neuroscience. 2007 Sep 7;148(3):766-74. Epub 2007 Aug 15.

40.

Mutational reversions during adaptive protein evolution.

DePristo MA, Hartl DL, Weinreich DM.

Mol Biol Evol. 2007 Aug;24(8):1608-10. Epub 2007 Jun 7.

PMID:
17556755
41.

Prostaglandin E2 depresses solitary tract-mediated synaptic transmission in the nucleus tractus solitarius.

Laaris N, Weinreich D.

Neuroscience. 2007 May 11;146(2):792-801. Epub 2007 Mar 23.

42.

Empirical fitness landscapes reveal accessible evolutionary paths.

Poelwijk FJ, Kiviet DJ, Weinreich DM, Tans SJ.

Nature. 2007 Jan 25;445(7126):383-6.

PMID:
17251971
43.

Calcium regulation in individual peripheral sensory nerve terminals of the rat.

Gover TD, Moreira TH, Kao JP, Weinreich D.

J Physiol. 2007 Jan 15;578(Pt 2):481-90. Epub 2006 Nov 9.

44.

Patterns and mechanisms of genetic and phenotypic differentiation in marine microbes.

Polz MF, Hunt DE, Preheim SP, Weinreich DM.

Philos Trans R Soc Lond B Biol Sci. 2006 Nov 29;361(1475):2009-21. Review.

45.

Calcium homeostasis in trigeminal ganglion cell bodies.

Gover TD, Moreira TH, Kao JP, Weinreich D.

Cell Calcium. 2007 Apr;41(4):389-96. Epub 2006 Oct 13.

PMID:
17046058
46.

Effects of intra-gene fitness interactions on the benefit of sexual recombination.

Watson RA, Weinreich DM, Wakeley J.

Biochem Soc Trans. 2006 Aug;34(Pt 4):560-1.

PMID:
16856860
47.

Caged vanilloid ligands for activation of TRPV1 receptors by 1- and 2-photon excitation.

Zhao J, Gover TD, Muralidharan S, Auston DA, Weinreich D, Kao JP.

Biochemistry. 2006 Apr 18;45(15):4915-26.

48.

Darwinian evolution can follow only very few mutational paths to fitter proteins.

Weinreich DM, Delaney NF, Depristo MA, Hartl DL.

Science. 2006 Apr 7;312(5770):111-4.

49.

Reflex regulation of airway sympathetic nerves in guinea-pigs.

Oh EJ, Mazzone SB, Canning BJ, Weinreich D.

J Physiol. 2006 Jun 1;573(Pt 2):549-64. Epub 2006 Mar 31.

50.

The role of interleukin 1 in growth and metastasis of human cancer xenografts.

Elaraj DM, Weinreich DM, Varghese S, Puhlmann M, Hewitt SM, Carroll NM, Feldman ED, Turner EM, Alexander HR.

Clin Cancer Res. 2006 Feb 15;12(4):1088-96.

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