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Items: 1 to 50 of 214

1.

Metabolic consequences of cystinuria.

Woodard LE, Welch RC, Veach RA, Beckermann TM, Sha F, Weinman EJ, Ikizler TA, Tischfield JA, Sahota A, Wilson MH.

BMC Nephrol. 2019 Jun 20;20(1):227. doi: 10.1186/s12882-019-1417-8.

2.

Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle.

Pera T, Tompkins E, Katz M, Wang B, Deshpande DA, Weinman EJ, Penn RB.

FASEB J. 2019 May 1:fj201900323R. doi: 10.1096/fj.201900323R. [Epub ahead of print]

PMID:
31042404
3.

Loss of NHERF-1 expression prevents dopamine-mediated Na-K-ATPase regulation in renal proximal tubule cells from rat models of hypertension: aged F344 rats and spontaneously hypertensive rats.

Barati MT, Ketchem CJ, Merchant ML, Kusiak WB, Jose PA, Weinman EJ, LeBlanc AJ, Lederer ED, Khundmiri SJ.

Am J Physiol Cell Physiol. 2017 Aug 1;313(2):C197-C206. doi: 10.1152/ajpcell.00219.2016. Epub 2017 May 17.

4.

Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain.

Ritter-Makinson SL, Paquet M, Bogenpohl JW, Rodin RE, Chris Yun C, Weinman EJ, Smith Y, Hall RA.

Neuroscience. 2017 Jun 14;353:58-75. doi: 10.1016/j.neuroscience.2017.03.060. Epub 2017 Apr 7.

5.

Restoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss.

He P, Zhao L, Zhu L, Weinman EJ, De Giorgio R, Koval M, Srinivasan S, Yun CC.

J Clin Invest. 2015 Sep;125(9):3519-31. doi: 10.1172/JCI79552. Epub 2015 Aug 10.

6.

Na(+) /H(+) exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury.

Li M, Mennone A, Soroka CJ, Hagey LR, Ouyang X, Weinman EJ, Boyer JL.

Hepatology. 2015 Oct;62(4):1227-36. doi: 10.1002/hep.27956. Epub 2015 Aug 22.

7.

Role of Na+/H+ exchanger regulatory factor 1 in forward trafficking of the type IIa Na+-Pi cotransporter.

Ketchem CJ, Khundmiri SJ, Gaweda AE, Murray R, Clark BJ, Weinman EJ, Lederer ED.

Am J Physiol Renal Physiol. 2015 Jul 15;309(2):F109-19.

8.

Integrated compensatory network is activated in the absence of NCC phosphorylation.

Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA.

J Clin Invest. 2015 May;125(5):2136-50. doi: 10.1172/JCI78558. Epub 2015 Apr 20.

9.

Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing.

Roy A, Goodman JH, Begum G, Donnelly BF, Pittman G, Weinman EJ, Sun D, Subramanya AR.

Am J Physiol Renal Physiol. 2015 Feb 15;308(4):F366-76. doi: 10.1152/ajprenal.00612.2014. Epub 2014 Dec 4.

10.

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.

Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, Cebotaru V, Chiaravalli M, Boletta A, Piontek K, Germino GG, Weinman EJ, Watnick T, Qian F.

Nat Commun. 2014 Nov 18;5:5482. doi: 10.1038/ncomms6482.

11.

Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells.

Yu P, Sun M, Villar VA, Zhang Y, Weinman EJ, Felder RA, Jose PA.

Cell Signal. 2014 Nov;26(11):2521-9. doi: 10.1016/j.cellsig.2014.07.003. Epub 2014 Jul 15.

12.

Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of reactive oxygen species production.

Yang Y, Cuevas S, Yang S, Villar VA, Escano C, Asico L, Yu P, Jiang X, Weinman EJ, Armando I, Jose PA.

Hypertension. 2014 Oct;64(4):825-32. doi: 10.1161/HYPERTENSIONAHA.114.03840. Epub 2014 Jul 14.

13.

Gastrointestinal phosphate handling in CKD and its association with cardiovascular disease.

Weinman EJ, Light PD, Suki WN.

Am J Kidney Dis. 2013 Nov;62(5):1006-11. doi: 10.1053/j.ajkd.2013.04.013. Epub 2013 Jun 12.

14.

D5 dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1.

Lu Q, Yang Y, Villar VA, Asico L, Jones JE, Yu P, Li H, Weinman EJ, Eisner GM, Jose PA.

Hypertens Res. 2013 Aug;36(8):684-90. doi: 10.1038/hr.2013.9. Epub 2013 Feb 21.

15.

NHE3 regulatory factor 1 (NHERF1) modulates intestinal sodium-dependent phosphate transporter (NaPi-2b) expression in apical microvilli.

Giral H, Cranston D, Lanzano L, Caldas Y, Sutherland E, Rachelson J, Dobrinskikh E, Weinman EJ, Doctor RB, Gratton E, Levi M.

J Biol Chem. 2012 Oct 12;287(42):35047-56. doi: 10.1074/jbc.M112.392415. Epub 2012 Aug 17.

16.

Bradycardia without "classical" EKG changes in hyperkalemic hemodialysis patients.

Mohanlal V, Haririan A, Weinman EJ.

Clin Nephrol. 2013 Dec;80(6):464-8. doi: 10.5414/CN107529.

PMID:
22784561
17.

NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormones.

Weinman EJ, Lederer ED.

Am J Physiol Renal Physiol. 2012 Aug 1;303(3):F321-7. doi: 10.1152/ajprenal.00093.2012. Epub 2012 Apr 25.

18.

NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains.

Cardone RA, Greco MR, Capulli M, Weinman EJ, Busco G, Bellizzi A, Casavola V, Antelmi E, Ambruosi B, Dell'Aquila ME, Paradiso A, Teti A, Rucci N, Reshkin SJ.

Mol Biol Cell. 2012 Jun;23(11):2028-40. doi: 10.1091/mbc.E11-11-0911. Epub 2012 Apr 11.

19.

PTH-mediated inhibition of the renal transport of phosphate.

Weinman EJ, Lederer ED.

Exp Cell Res. 2012 May 15;318(9):1027-32. doi: 10.1016/j.yexcr.2012.02.037. Epub 2012 Mar 5. Review. No abstract available.

20.

Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone.

Weinman EJ, Steplock D, Shenolikar S, Biswas R.

J Biol Chem. 2011 Oct 28;286(43):37216-21. doi: 10.1074/jbc.M111.288357. Epub 2011 Sep 9.

21.

The regulation of renal phosphate transport.

Blaine J, Weinman EJ, Cunningham R.

Adv Chronic Kidney Dis. 2011 Mar;18(2):77-84. doi: 10.1053/j.ackd.2011.01.005. Review.

PMID:
21406291
22.

Increased renal dopamine and acute renal adaptation to a high-phosphate diet.

Weinman EJ, Biswas R, Steplock D, Wang P, Lau YS, Desir GV, Shenolikar S.

Am J Physiol Renal Physiol. 2011 May;300(5):F1123-9. doi: 10.1152/ajprenal.00744.2010. Epub 2011 Feb 16.

23.

Dopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum kidney cells.

Salyer S, Lesousky N, Weinman EJ, Clark BJ, Lederer ED, Khundmiri SJ.

Am J Physiol Cell Physiol. 2011 Mar;300(3):C425-34. doi: 10.1152/ajpcell.00357.2010. Epub 2010 Dec 15.

24.

Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice.

Evan AP, Weinman EJ, Wu XR, Lingeman JE, Worcester EM, Coe FL.

Urol Res. 2010 Dec;38(6):439-52. doi: 10.1007/s00240-010-0330-1. Epub 2010 Nov 10.

25.

Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells.

Weinman EJ, Steplock D, Shenolikar S, Blanpied TA.

Am J Physiol Renal Physiol. 2011 Jan;300(1):F231-5. doi: 10.1152/ajprenal.00532.2010. Epub 2010 Nov 3.

26.

Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.

Weinman EJ, Steplock D, Zhang Y, Biswas R, Bloch RJ, Shenolikar S.

J Biol Chem. 2010 Aug 13;285(33):25134-8. doi: 10.1074/jbc.M110.132423. Epub 2010 Jun 22.

27.

Nerve growth factor-regulated emergence of functional delta-opioid receptors.

Bie B, Zhang Z, Cai YQ, Zhu W, Zhang Y, Dai J, Lowenstein CJ, Weinman EJ, Pan ZZ.

J Neurosci. 2010 Apr 21;30(16):5617-28. doi: 10.1523/JNEUROSCI.5296-09.2010.

28.

NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function.

Li M, Wang W, Soroka CJ, Mennone A, Harry K, Weinman EJ, Boyer JL.

J Biol Chem. 2010 Jun 18;285(25):19299-307. doi: 10.1074/jbc.M109.096081. Epub 2010 Apr 19.

29.

Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney.

Weinman EJ, Biswas R, Steplock D, Douglass TS, Cunningham R, Shenolikar S.

J Biol Chem. 2010 Apr 30;285(18):13454-60. doi: 10.1074/jbc.M109.094359. Epub 2010 Mar 3.

30.

PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.

Weinman EJ, Steplock D, Cha B, Kovbasnjuk O, Frost NA, Cunningham R, Shenolikar S, Blanpied TA, Donowitz M.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1560-5. doi: 10.1152/ajprenal.90657.2008. Epub 2009 Sep 30.

31.

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.

Singh AK, Riederer B, Krabbenhöft A, Rausch B, Bonhagen J, Lehmann U, de Jonge HR, Donowitz M, Yun C, Weinman EJ, Kocher O, Hogema BM, Seidler U.

J Clin Invest. 2009 Mar;119(3):540-50. doi: 10.1172/JCI35541. Epub 2009 Feb 16.

32.

Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells.

Cunningham R, Biswas R, Brazie M, Steplock D, Shenolikar S, Weinman EJ.

Am J Physiol Renal Physiol. 2009 Feb;296(2):F355-61. doi: 10.1152/ajprenal.90426.2008. Epub 2008 Nov 5.

33.

The ROMK potassium channel is present in mammalian urinary tract epithelia and muscle.

Spector DA, Yang Q, Klopouh L, Deng J, Weinman EJ, Steplock DA, Biswas R, Brazie MF, Liu J, Wade JB.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1658-65. doi: 10.1152/ajprenal.00022.2008. Epub 2008 Sep 17.

34.

Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.

Broere N, Chen M, Cinar A, Singh AK, Hillesheim J, Riederer B, Lünnemann M, Rottinghaus I, Krabbenhöft A, Engelhardt R, Rausch B, Weinman EJ, Donowitz M, Hubbard A, Kocher O, de Jonge HR, Hogema BM, Seidler U.

Pflugers Arch. 2009 Mar;457(5):1079-91. doi: 10.1007/s00424-008-0579-1. Epub 2008 Aug 29.

35.

Cholesterol embolization syndrome induced by thrombolytic therapy.

Hitti WA, Wali RK, Weinman EJ, Drachenberg C, Briglia A.

Am J Cardiovasc Drugs. 2008;8(1):27-34. Review. Erratum in: Am J Cardiovasc Drugs. 2008;8(6):427. Weiman, Edward J [corrected to Weinman, Edward J].

PMID:
18303935
36.

Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.

Cunningham R, Esmaili A, Brown E, Biswas RS, Murtazina R, Donowitz M, Dijkman HB, van der Vlag J, Hogema BM, De Jonge HR, Shenolikar S, Wade JB, Weinman EJ.

Am J Physiol Renal Physiol. 2008 Apr;294(4):F1001-7. doi: 10.1152/ajprenal.00504.2007. Epub 2008 Feb 6.

37.

Novel regulatory function for NHERF-1 in Npt2a transcription.

Khundmiri SJ, Ahmad A, Bennett RE, Weinman EJ, Steplock D, Cole J, Baumann PD, Lewis J, Singh S, Clark BJ, Lederer ED.

Am J Physiol Renal Physiol. 2008 Apr;294(4):F840-9. doi: 10.1152/ajprenal.00180.2007. Epub 2008 Jan 23.

38.

Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.

Pan Y, Weinman EJ, Dai JL.

Breast Cancer Res. 2008;10(1):R5. doi: 10.1186/bcr1846. Epub 2008 Jan 11.

39.

Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1.

Weinman EJ, Biswas RS, Peng G, Shen L, Turner CL, E X, Steplock D, Shenolikar S, Cunningham R.

J Clin Invest. 2007 Nov;117(11):3412-20. Erratum in: J Clin Invest. 2008 Jan;118(1):387. Peng, Quihong [corrected to Peng, Guihong]. J Clin Invest. 2013 Jun;123(6):2752.

40.

Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.

Broere N, Hillesheim J, Tuo B, Jorna H, Houtsmuller AB, Shenolikar S, Weinman EJ, Donowitz M, Seidler U, de Jonge HR, Hogema BM.

J Biol Chem. 2007 Dec 28;282(52):37575-84. Epub 2007 Oct 18.

41.

Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets.

Voltz JW, Brush M, Sikes S, Steplock D, Weinman EJ, Shenolikar S.

J Biol Chem. 2007 Nov 16;282(46):33879-87. Epub 2007 Sep 25. Erratum in: J Biol Chem. 2008 Feb 15;283(7):4459.

42.

Cell-matrix interactions modulate transepithelial phosphate transport in P(i)-deprived OK cells.

Barac-Nieto M, Weinman EJ, Spitzer A.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1272-7. Epub 2007 Jul 25.

43.

Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.

Murtazina R, Kovbasnjuk O, Zachos NC, Li X, Chen Y, Hubbard A, Hogema BM, Steplock D, Seidler U, Hoque KM, Tse CM, De Jonge HR, Weinman EJ, Donowitz M.

J Biol Chem. 2007 Aug 24;282(34):25141-51. Epub 2007 Jun 19.

44.

Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.

Cunningham R, Brazie M, Kanumuru S, E X, Biswas R, Wang F, Steplock D, Wade JB, Anzai N, Endou H, Shenolikar S, Weinman EJ.

J Am Soc Nephrol. 2007 May;18(5):1419-25. Epub 2007 Apr 4.

45.

The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

Cardone RA, Bellizzi A, Busco G, Weinman EJ, Dell'Aquila ME, Casavola V, Azzariti A, Mangia A, Paradiso A, Reshkin SJ.

Mol Biol Cell. 2007 May;18(5):1768-80. Epub 2007 Mar 1.

46.

Acute renal failure and nephrotic range proteinuria due to amyloidosis in an HIV-infected patient.

Chan-Tack KM, Ahuja N, Weinman EJ, Wali RK, Uche A, Greisman LA, Drachenberg C, Hawkins PN, Redfield RR.

Am J Med Sci. 2006 Dec;332(6):364-7.

PMID:
17170630
47.

Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice.

Capuano P, Bacic D, Roos M, Gisler SM, Stange G, Biber J, Kaissling B, Weinman EJ, Shenolikar S, Wagner CA, Murer H.

Am J Physiol Cell Physiol. 2007 Feb;292(2):C927-34. Epub 2006 Sep 20.

48.

Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.

Cunningham R, Steplock D, E X, Biswas RS, Wang F, Shenolikar S, Weinman EJ.

Am J Physiol Renal Physiol. 2006 Oct;291(4):F896-901. Epub 2006 May 16.

49.

The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.

Weinman EJ, Hall RA, Friedman PA, Liu-Chen LY, Shenolikar S.

Annu Rev Physiol. 2006;68:491-505. Review.

PMID:
16460281
50.

Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice.

Weinman EJ, Mohanlal V, Stoycheff N, Wang F, Steplock D, Shenolikar S, Cunningham R.

Am J Physiol Renal Physiol. 2006 Apr;290(4):F838-43. Epub 2005 Oct 25. Erratum in: Am J Physiol Renal Physiol. 2006 Jul;291(1):F254-5.

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