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Items: 1 to 50 of 127

1.

Post-Transcriptional Noise Control.

Hansen MMK, Weinberger LS.

Bioessays. 2019 Jul;41(7):e1900044. doi: 10.1002/bies.201900044. Epub 2019 Jun 21.

2.

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.

Zviran A, Mor N, Rais Y, Gingold H, Peles S, Chomsky E, Viukov S, Buenrostro JD, Scognamiglio R, Weinberger L, Manor YS, Krupalnik V, Zerbib M, Hezroni H, Jaitin DA, Larastiaso D, Gilad S, Benjamin S, Gafni O, Mousa A, Ayyash M, Sheban D, Bayerl J, Aguilera-Castrejon A, Massarwa R, Maza I, Hanna S, Stelzer Y, Ulitsky I, Greenleaf WJ, Tanay A, Trumpp A, Amit I, Pilpel Y, Novershtern N, Hanna JH.

Cell Stem Cell. 2019 Feb 7;24(2):328-341.e9. doi: 10.1016/j.stem.2018.11.014. Epub 2018 Dec 13.

PMID:
30554962
3.

Cytoplasmic Amplification of Transcriptional Noise Generates Substantial Cell-to-Cell Variability.

Hansen MMK, Desai RV, Simpson ML, Weinberger LS.

Cell Syst. 2018 Oct 24;7(4):384-397.e6. doi: 10.1016/j.cels.2018.08.002. Epub 2018 Sep 19.

4.

Feedback-mediated signal conversion promotes viral fitness.

Vardi N, Chaturvedi S, Weinberger LS.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8803-E8810. doi: 10.1073/pnas.1802905115. Epub 2018 Aug 27.

5.

A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization.

Hansen MMK, Wen WY, Ingerman E, Razooky BS, Thompson CE, Dar RD, Chin CW, Simpson ML, Weinberger LS.

Cell. 2018 Jun 14;173(7):1609-1621.e15. doi: 10.1016/j.cell.2018.04.005. Epub 2018 May 10.

6.

Linking Mental Disorder and Risk in Sexually Violent Person Assessments.

Weinberger LE, Sreenivasan S, Azizian A, Garrick T.

J Am Acad Psychiatry Law. 2018 Mar;46(1):63-70. Review.

PMID:
29618537
7.

A Bioreactor Method to Generate High-titer, Genetically Stable, Clinical-isolate Human Cytomegalovirus.

Saykally VR, Rast LI, Sasaki J, Jung SY, Bolovan-Fritts C, Weinberger LS.

Bio Protoc. 2017 Nov 5;7(21). pii: e2589. doi: 10.21769/BioProtoc.2589.

8.

Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean.

Razooky BS, Cao Y, Hansen MMK, Perelson AS, Simpson ML, Weinberger LS.

PLoS Biol. 2017 Oct 18;15(10):e2000841. doi: 10.1371/journal.pbio.2000841. eCollection 2017 Oct.

9.

Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.

Pai A, Weinberger LS.

Annu Rev Virol. 2017 Sep 29;4(1):469-490. doi: 10.1146/annurev-virology-110615-035606. Epub 2017 Aug 11. Review.

10.

Understanding and Treating Offenders with Serious Mental Illness in Public Sector Mental Health.

Lamb HR, Weinberger LE.

Behav Sci Law. 2017 Jul;35(4):303-318. doi: 10.1002/bsl.2292. Epub 2017 Jun 14.

PMID:
28612397
11.

Transient Thresholding: A Mechanism Enabling Noncooperative Transcriptional Circuitry to Form a Switch.

Aull KH, Tanner EJ, Thomson M, Weinberger LS.

Biophys J. 2017 Jun 6;112(11):2428-2438. doi: 10.1016/j.bpj.2017.05.002.

12.

Transcriptional programs that control expression of the autoimmune regulator gene Aire.

Herzig Y, Nevo S, Bornstein C, Brezis MR, Ben-Hur S, Shkedy A, Eisenberg-Bord M, Levi B, Delacher M, Goldfarb Y, David E, Weinberger L, Viukov S, Ben-Dor S, Giraud M, Hanna JH, Breiling A, Lyko F, Amit I, Feuerer M, Abramson J.

Nat Immunol. 2017 Feb;18(2):161-172. doi: 10.1038/ni.3638. Epub 2016 Dec 12.

PMID:
27941786
13.

Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels.

Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS.

PLoS One. 2016 Jul 28;11(7):e0158298. doi: 10.1371/journal.pone.0158298. eCollection 2016.

14.

The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7.

Ali I, Ramage H, Boehm D, Dirk LM, Sakane N, Hanada K, Pagans S, Kaehlcke K, Aull K, Weinberger L, Trievel R, Schnoelzer M, Kamada M, Houtz R, Ott M.

J Biol Chem. 2016 Jul 29;291(31):16240-8. doi: 10.1074/jbc.M116.735415. Epub 2016 May 27.

15.

Conflicting Selection Pressures Will Constrain Viral Escape from Interfering Particles: Principles for Designing Resistance-Proof Antivirals.

Rast LI, Rouzine IM, Rozhnova G, Bishop L, Weinberger AD, Weinberger LS.

PLoS Comput Biol. 2016 May 6;12(5):e1004799. doi: 10.1371/journal.pcbi.1004799. eCollection 2016 May.

16.

Exploiting Genetic Interference for Antiviral Therapy.

Tanner EJ, Kirkegaard KA, Weinberger LS.

PLoS Genet. 2016 May 5;12(5):e1005986. doi: 10.1371/journal.pgen.1005986. eCollection 2016 May. Review.

17.

Rediscovering the Concept of Asylum for Persons with Serious Mental Illness.

Lamb HR, Weinberger LE.

J Am Acad Psychiatry Law. 2016 Mar;44(1):106-10.

PMID:
26944750
18.

Dynamic stem cell states: naive to primed pluripotency in rodents and humans.

Weinberger L, Ayyash M, Novershtern N, Hanna JH.

Nat Rev Mol Cell Biol. 2016 Mar;17(3):155-69. doi: 10.1038/nrm.2015.28. Epub 2016 Feb 10. Review.

PMID:
26860365
19.

A minimal fate-selection switch.

Weinberger LS.

Curr Opin Cell Biol. 2015 Dec;37:111-8. doi: 10.1016/j.ceb.2015.10.005. Epub 2015 Nov 21. Review.

20.

The Low Noise Limit in Gene Expression.

Dar RD, Razooky BS, Weinberger LS, Cox CD, Simpson ML.

PLoS One. 2015 Oct 21;10(10):e0140969. doi: 10.1371/journal.pone.0140969. eCollection 2015.

21.

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors.

Maza I, Caspi I, Zviran A, Chomsky E, Rais Y, Viukov S, Geula S, Buenrostro JD, Weinberger L, Krupalnik V, Hanna S, Zerbib M, Dutton JR, Greenleaf WJ, Massarwa R, Novershtern N, Hanna JH.

Nat Biotechnol. 2015 Jul;33(7):769-74. doi: 10.1038/nbt.3270. Epub 2015 Jun 22.

22.

Corrigendum: Derivation of novel human ground state naive pluripotent stem cells.

Gafni O, Weinberger L, Mansour AA, Manor YS, Chomsky E, Ben-Yosef D, Kalma Y, Viukov S, Maza I, Zviran A, Rais Y, Shipony Z, Mukamel Z, Krupalnik V, Zerbib M, Geula S, Caspi I, Schneir D, Shwartz T, Gilad S, Amann-Zalcenstein D, Benjamin S, Amit I, Tanay A, Massarwa R, Novershtern N, Hanna JH.

Nature. 2015 Apr 30;520(7549):710. doi: 10.1038/nature14370. Epub 2015 Apr 1. No abstract available.

PMID:
25830888
23.

Corrigendum: Deterministic direct reprogramming of somatic cells to pluripotency.

Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH.

Nature. 2015 Apr 30;520(7549):710. doi: 10.1038/nature14369. Epub 2015 Apr 1. No abstract available.

PMID:
25830885
24.

An evolutionary role for HIV latency in enhancing viral transmission.

Rouzine IM, Weinberger AD, Weinberger LS.

Cell. 2015 Feb 26;160(5):1002-1012. doi: 10.1016/j.cell.2015.02.017.

25.

A hardwired HIV latency program.

Razooky BS, Pai A, Aull K, Rouzine IM, Weinberger LS.

Cell. 2015 Feb 26;160(5):990-1001. doi: 10.1016/j.cell.2015.02.009.

26.

Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting.

Jung SY, Notton T, Fong E, Shusteff M, Weinberger LS.

Lab Chip. 2015 Feb 21;15(4):1000-3. doi: 10.1039/c4lc01342e.

27.

SOX17 is a critical specifier of human primordial germ cell fate.

Irie N, Weinberger L, Tang WW, Kobayashi T, Viukov S, Manor YS, Dietmann S, Hanna JH, Surani MA.

Cell. 2015 Jan 15;160(1-2):253-68. doi: 10.1016/j.cell.2014.12.013. Epub 2014 Dec 24.

28.

Decarceration of U.S. jails and prisons: where will persons with serious mental illness go?

Lamb HR, Weinberger LE.

J Am Acad Psychiatry Law. 2014;42(4):489-94. Review.

PMID:
25492076
29.

Stochastic variability in HIV affects viral eradication.

Rouzine IM, Razooky BS, Weinberger LS.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13251-2. doi: 10.1073/pnas.1413362111. Epub 2014 Sep 8. No abstract available.

30.

End-of-life mental health assessments for older aged, medically ill persons with expressed desire to die.

Weinberger LE, Sreenivasan S, Garrick T.

J Am Acad Psychiatry Law. 2014;42(3):350-61. Review.

PMID:
25187288
31.

The case for transmissible antivirals to control population-wide infectious disease.

Notton T, SardanyƩs J, Weinberger AD, Weinberger LS.

Trends Biotechnol. 2014 Aug;32(8):400-5. doi: 10.1016/j.tibtech.2014.06.006. Epub 2014 Jul 10. Review.

PMID:
25017994
32.

Screening for noise in gene expression identifies drug synergies.

Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS.

Science. 2014 Jun 20;344(6190):1392-6. doi: 10.1126/science.1250220. Epub 2014 Jun 5.

33.

Fifteen years later: hard and soft selection sweeps confirm a large population number for HIV in vivo.

Rouzine IM, Coffin JM, Weinberger LS.

PLoS Genet. 2014 Feb 20;10(2):e1004179. doi: 10.1371/journal.pgen.1004179. eCollection 2014 Feb. No abstract available.

34.

Acoustic focusing with engineered node locations for high-performance microfluidic particle separation.

Fong EJ, Johnston AC, Notton T, Jung SY, Rose KA, Weinberger LS, Shusteff M.

Analyst. 2014 Mar 7;139(5):1192-200. doi: 10.1039/c4an00034j. Epub 2014 Jan 22.

PMID:
24448925
35.

Stochastic fate selection in HIV-infected patients.

Weinberger AD, Weinberger LS.

Cell. 2013 Oct 24;155(3):497-9. doi: 10.1016/j.cell.2013.09.039. Epub 2013 Oct 24.

36.

Derivation of novel human ground state naive pluripotent stem cells.

Gafni O, Weinberger L, Mansour AA, Manor YS, Chomsky E, Ben-Yosef D, Kalma Y, Viukov S, Maza I, Zviran A, Rais Y, Shipony Z, Mukamel Z, Krupalnik V, Zerbib M, Geula S, Caspi I, Schneir D, Shwartz T, Gilad S, Amann-Zalcenstein D, Benjamin S, Amit I, Tanay A, Massarwa R, Novershtern N, Hanna JH.

Nature. 2013 Dec 12;504(7479):282-6. doi: 10.1038/nature12745. Epub 2013 Oct 30. Erratum in: Nature. 2015 Apr 30;520(7549):710.

PMID:
24172903
37.

Deterministic direct reprogramming of somatic cells to pluripotency.

Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH.

Nature. 2013 Oct 3;502(7469):65-70. doi: 10.1038/nature12587. Epub 2013 Sep 18. Erratum in: Nature. 2015 Apr 30;520(7549):710.

PMID:
24048479
38.

Reply to "Coadaptive stability of interfering particles with HIV-1 when there is an evolutionary conflict".

Rouzine IM, Weinberger LS.

J Virol. 2013 Sep;87(17):9960-2. doi: 10.1128/JVI.00932-13. No abstract available.

39.

Some perspectives on criminalization.

Lamb HR, Weinberger LE.

J Am Acad Psychiatry Law. 2013;41(2):287-93.

PMID:
23771942
40.

Evolution of the psychological autopsy: fifty years of experience at the Los Angeles County Chief Medical Examiner-Coroner's Office.

Botello T, Noguchi T, Sathyavagiswaran L, Weinberger LE, Gross BH.

J Forensic Sci. 2013 Jul;58(4):924-6. doi: 10.1111/1556-4029.12138. Epub 2013 Mar 28.

PMID:
23551031
41.

Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies.

Gardner TJ, Bolovan-Fritts C, Teng MW, Redmann V, Kraus TA, Sperling R, Moran T, Britt W, Weinberger LS, Tortorella D.

Clin Vaccine Immunol. 2013 Apr;20(4):540-50. doi: 10.1128/CVI.00644-12. Epub 2013 Feb 6.

42.

An endogenous accelerator for viral gene expression confers a fitness advantage.

Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS.

Cell. 2012 Dec 21;151(7):1569-80. doi: 10.1016/j.cell.2012.11.051. Erratum in: Cell. 2013 Feb 28;152(5):1195.

43.

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M.

Cell Cycle. 2013 Feb 1;12(3):452-62. doi: 10.4161/cc.23309. Epub 2012 Feb 1.

44.

Design requirements for interfering particles to maintain coadaptive stability with HIV-1.

Rouzine IM, Weinberger LS.

J Virol. 2013 Feb;87(4):2081-93. doi: 10.1128/JVI.02741-12. Epub 2012 Dec 5.

45.

Transcriptional burst frequency and burst size are equally modulated across the human genome.

Dar RD, Razooky BS, Singh A, Trimeloni TV, McCollum JM, Cox CD, Simpson ML, Weinberger LS.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17454-9. doi: 10.1073/pnas.1213530109. Epub 2012 Oct 11.

46.

Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes.

Razooky BS, Gutierrez E, Terry VH, Spina CA, Groisman A, Weinberger LS.

Lab Chip. 2012 Nov 7;12(21):4305-12. doi: 10.1039/c2lc40170c.

47.

Dynamics of protein noise can distinguish between alternate sources of gene-expression variability.

Singh A, Razooky BS, Dar RD, Weinberger LS.

Mol Syst Biol. 2012;8:607. doi: 10.1038/msb.2012.38.

48.

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.

Mansour AA, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, Krupalnik V, Zerbib M, Amann-Zalcenstein D, Maza I, Geula S, Viukov S, Holtzman L, Pribluda A, Canaani E, Horn-Saban S, Amit I, Novershtern N, Hanna JH.

Nature. 2012 Aug 16;488(7411):409-13. doi: 10.1038/nature11272.

PMID:
22801502
49.

Expression noise and acetylation profiles distinguish HDAC functions.

Weinberger L, Voichek Y, Tirosh I, Hornung G, Amit I, Barkai N.

Mol Cell. 2012 Jul 27;47(2):193-202. doi: 10.1016/j.molcel.2012.05.008. Epub 2012 Jun 7.

50.

Meeting the needs of those persons with serious mental illness who are most likely to become criminalized.

Lamb HR, Weinberger LE.

J Am Acad Psychiatry Law. 2011;39(4):549-54.

PMID:
22159983

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