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Items: 1 to 50 of 156

1.

Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology.

Blennow K, Chen C, Cicognola C, Wildsmith KR, Manser PT, Bohorquez SMS, Zhang Z, Xie B, Peng J, Hansson O, Kvartsberg H, Portelius E, Zetterberg H, Lashley T, Brinkmalm G, Kerchner GA, Weimer RM, Ye K, Höglund K.

Brain. 2019 Dec 13. pii: awz346. doi: 10.1093/brain/awz346. [Epub ahead of print]

PMID:
31834365
2.

CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions.

Easley-Neal C, Foreman O, Sharma N, Zarrin AA, Weimer RM.

Front Immunol. 2019 Sep 20;10:2199. doi: 10.3389/fimmu.2019.02199. eCollection 2019.

3.

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.

Lin W, Xu D, Austin CD, Caplazi P, Senger K, Sun Y, Jeet S, Young J, Delarosa D, Suto E, Huang Z, Zhang J, Yan D, Corzo C, Barck K, Rajan S, Looney C, Gandham V, Lesch J, Liang WC, Mai E, Ngu H, Ratti N, Chen Y, Misner D, Lin T, Danilenko D, Katavolos P, Doudemont E, Uppal H, Eastham J, Mak J, de Almeida PE, Bao K, Hadadianpour A, Keir M, Carano RAD, Diehl L, Xu M, Wu Y, Weimer RM, DeVoss J, Lee WP, Balazs M, Walsh K, Alatsis KR, Martin F, Zarrin AA.

Front Immunol. 2019 Sep 4;10:2019. doi: 10.3389/fimmu.2019.02019. eCollection 2019.

4.

Disruption of IRE1α through its kinase domain attenuates multiple myeloma.

Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16420-16429. doi: 10.1073/pnas.1906999116. Epub 2019 Aug 1.

5.

Cross-sectional associations between [18F]GTP1 tau PET and cognition in Alzheimer's disease.

Teng E, Ward M, Manser PT, Sanabria-Bohorquez S, Ray RD, Wildsmith KR, Baker S, Kerchner GA, Weimer RM.

Neurobiol Aging. 2019 Sep;81:138-145. doi: 10.1016/j.neurobiolaging.2019.05.026. Epub 2019 Jun 6.

PMID:
31280117
6.

[18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer's disease.

Sanabria Bohórquez S, Marik J, Ogasawara A, Tinianow JN, Gill HS, Barret O, Tamagnan G, Alagille D, Ayalon G, Manser P, Bengtsson T, Ward M, Williams SP, Kerchner GA, Seibyl JP, Marek K, Weimer RM.

Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):2077-2089. doi: 10.1007/s00259-019-04399-0. Epub 2019 Jun 28.

PMID:
31254035
7.

Patients with idiopathic recurrent miscarriage have abnormally high TGFß+ blood NK, NKT and T cells in the presence of abnormally low TGFß plasma levels.

Zhu L, Aly M, Kuon RJ, Toth B, Wang H, Karakizlis H, Weimer R, Morath C, Ibrahim E, Ekpoom N, Opelz G, Daniel V.

BMC Immunol. 2019 Mar 4;20(1):10. doi: 10.1186/s12865-019-0290-3.

8.

AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair.

Lengert N, Mirsch J, Weimer RN, Schumann E, Haub P, Drossel B, Löbrich M.

Sci Rep. 2018 Nov 23;8(1):17282. doi: 10.1038/s41598-018-35660-5.

9.

Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

Katschke KJ Jr, Xi H, Cox C, Truong T, Malato Y, Lee WP, McKenzie B, Arceo R, Tao J, Rangell L, Reichelt M, Diehl L, Elstrott J, Weimer RM, van Lookeren Campagne M.

Sci Rep. 2018 Aug 24;8(1):13055. doi: 10.1038/s41598-018-30162-w.

10.

Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

Katschke KJ Jr, Xi H, Cox C, Truong T, Malato Y, Lee WP, McKenzie B, Arceo R, Tao J, Rangell L, Reichelt M, Diehl L, Elstrott J, Weimer RM, van Lookeren Campagne M.

Sci Rep. 2018 May 9;8(1):7348. doi: 10.1038/s41598-018-25557-8. Erratum in: Sci Rep. 2018 Aug 24;8(1):13055.

11.

Changes of NK cell subsets with time post-transplant in peripheral blood of renal transplant recipients.

Zhu L, Aly M, Wang H, Karakizlis H, Weimer R, Morath C, Kuon RJ, Toth B, Ekpoom N, Opelz G, Daniel V.

Transpl Immunol. 2018 Aug;49:59-71. doi: 10.1016/j.trim.2018.04.005. Epub 2018 Apr 24.

PMID:
29702201
12.

Increased natural killer cell subsets with inhibitory cytokines and inhibitory surface receptors in patients with recurrent miscarriage and decreased or normal subsets in kidney transplant recipients late post-transplant.

Zhu L, Aly M, Wang H, Karakizlis H, Weimer R, Morath C, Kuon RJ, Toth B, Ekpoom N, Opelz G, Daniel V.

Clin Exp Immunol. 2018 Aug;193(2):241-254. doi: 10.1111/cei.13142. Epub 2018 May 31.

13.

Decreased NK cell immunity in kidney transplant recipients late post-transplant and increased NK-cell immunity in patients with recurrent miscarriage.

Zhu L, Aly M, Wang H, Karakizlis H, Weimer R, Morath C, Kuon RJ, Toth B, Opelz G, Daniel V.

PLoS One. 2017 Oct 17;12(10):e0186349. doi: 10.1371/journal.pone.0186349. eCollection 2017.

14.

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.

Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, Siu M, Patel S, Modrusan Z, Liu X, Rudhard Y, Baca M, Gustafson A, Kaminker J, Carano RAD, Huang EJ, Foreman O, Weimer R, Scearce-Levie K, Lewcock JW.

Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394. doi: 10.1126/scitranslmed.aag0394.

15.

Low utility of serum 25-hydroxyvitamin D3 and 1, 25-dihydroxyvitamin D3 in predicting peripheral Treg and Th17 cell counts in ESRD and renal transplant patients.

Aly MG, Zhu L, Weimer R, Opelz G, Morath C, Kuon R, Tohamy M, Saadi G, Soliman M, Ibrahim W, Daniel V.

Transpl Immunol. 2017 Aug;43-44:3-10. doi: 10.1016/j.trim.2017.07.003. Epub 2017 Jul 27.

PMID:
28757397
16.

Correction: Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function.

Trojan K, Unterrainer C, Weimer R, Bulut N, Morath C, Aly M, Zhu L, Opelz G, Daniel V.

PLoS One. 2017 May 31;12(5):e0179069. doi: 10.1371/journal.pone.0179069. eCollection 2017.

17.

Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function.

Trojan K, Unterrainer C, Weimer R, Bulut N, Morath C, Aly M, Zhu L, Opelz G, Daniel V.

PLoS One. 2017 Mar 15;12(3):e0173773. doi: 10.1371/journal.pone.0173773. eCollection 2017. Erratum in: PLoS One. 2017 May 31;12 (5):e0179069.

18.

Association of peripheral NK cell counts with Helios+ IFN-γ- Tregs in patients with good long-term renal allograft function.

Trojan K, Zhu L, Aly M, Weimer R, Bulut N, Morath C, Opelz G, Daniel V.

Clin Exp Immunol. 2017 Jun;188(3):467-479. doi: 10.1111/cei.12945. Epub 2017 Mar 13.

19.

Metabolic parameters and oxidative balance in juvenile Rhamdia quelen exposed to rice paddy herbicides: Roundup®, Primoleo®, and Facet®.

Persch TSP, Weimer RN, Freitas BS, Oliveira GT.

Chemosphere. 2017 May;174:98-109. doi: 10.1016/j.chemosphere.2017.01.092. Epub 2017 Jan 20.

20.

IFNy+ and IFNy- Treg subsets with stable and unstable Foxp3 expression in kidney transplant recipients with good long-term graft function.

Trojan K, Unterrainer C, Aly M, Zhu L, Weimer R, Bulut N, Morath C, Opelz G, Daniel V.

Transpl Immunol. 2016 Oct 29. pii: S0966-3274(16)30124-1. doi: 10.1016/j.trim.2016.10.003. [Epub ahead of print]

PMID:
27989714
21.

Kinetic Modeling of the Tau PET Tracer 18F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.

Barret O, Alagille D, Sanabria S, Comley RA, Weimer RM, Borroni E, Mintun M, Seneca N, Papin C, Morley T, Marek K, Seibyl JP, Tamagnan GD, Jennings D.

J Nucl Med. 2017 Jul;58(7):1124-1131. doi: 10.2967/jnumed.116.182881. Epub 2016 Dec 1.

22.

Monitoring of complement activation biomarkers and eculizumab in complement-mediated renal disorders.

Wehling C, Amon O, Bommer M, Hoppe B, Kentouche K, Schalk G, Weimer R, Wiesener M, Hohenstein B, Tönshoff B, Büscher R, Fehrenbach H, Gök ÖN, Kirschfink M.

Clin Exp Immunol. 2017 Feb;187(2):304-315. doi: 10.1111/cei.12890. Epub 2016 Nov 25.

23.

Donor-specific antibodies require preactivated immune system to harm renal transplant.

Süsal C, Döhler B, Ruhenstroth A, Morath C, Slavcev A, Fehr T, Wagner E, Krüger B, Rees M, Balen S, Živčić-Ćosić S, Norman DJ, Kuypers D, Emonds MP, Pisarski P, Bösmüller C, Weimer R, Mytilineos J, Scherer S, Tran TH, Gombos P, Schemmer P, Zeier M, Opelz G; A Collaborative Transplant Study Report.

EBioMedicine. 2016 Jul;9:366-371. doi: 10.1016/j.ebiom.2016.06.006. Epub 2016 Jun 5.

24.

Low-dose oral cholecalciferol is associated with higher numbers of Helios(+) and total Tregs than oral calcitriol in renal allograft recipients: an observational study.

Aly MG, Trojan K, Weimer R, Morath C, Opelz G, Tohamy MA, Daniel V.

BMC Pharmacol Toxicol. 2016 Jun 14;17(1):24. doi: 10.1186/s40360-016-0066-9.

25.

Modelling (137)Cs concentrations in moose (1986-2012) from areas highly contaminated by the Chernobyl fallout.

Weimer RN, Sundell-Bergman S, Sonesten L, Wikenros C, Rosén K.

J Environ Radioact. 2016 Aug;160:112-22. doi: 10.1016/j.jenvrad.2016.04.021. Epub 2016 May 7.

PMID:
27162195
26.

High-urgency kidney transplantation in the Eurotransplant Kidney Allocation System: success or waste of organs? The Eurotransplant 15-year all-centre survey.

Assfalg V, Hüser N, van Meel M, Haller B, Rahmel A, de Boer J, Matevossian E, Novotny A, Knops N, Weekers L, Friess H, Pratschke J, Függer R, Janko O, Rasoul-Rockenschaub S, Bosmans JL, Broeders N, Peeters P, Mourad M, Kuypers D, Slaviček J, Muehlfeld A, Sommer F, Viebahn R, Pascher A, van der Giet M, Zantvoort F, Woitas RP, Putz J, Grabitz K, Kribben A, Hauser I, Pisarski P, Weimer R, Lorf T, Fornara P, Morath C, Nashan B, Lehner F, Kliem V, Sester U, Grimm MO, Feldkamp T, Kleinert R, Arns W, Mönch C, Schoenberg MB, Nitschke M, Krüger B, Thorban S, Arbogast HP, Wolters HH, Maier T, Lutz J, Heller K, Banas B, Hakenberg O, Kalus M, Nadalin S, Keller F, Lopau K, Bemelman FJ, Nurmohamed S, Sanders JS, de Fijter JW, Christiaans M, Hilbrands L, Betjes M, van Zuilen A, Heemann U.

Nephrol Dial Transplant. 2016 Sep;31(9):1515-22. doi: 10.1093/ndt/gfv446. Epub 2016 Feb 4.

27.

IL-33 amplifies an innate immune response in the degenerating retina.

Xi H, Katschke KJ Jr, Li Y, Truong T, Lee WP, Diehl L, Rangell L, Tao J, Arceo R, Eastham-Anderson J, Hackney JA, Iglesias A, Cote-Sierra J, Elstrott J, Weimer RM, van Lookeren Campagne M.

J Exp Med. 2016 Feb 8;213(2):189-207. doi: 10.1084/jem.20150894. Epub 2016 Jan 11.

28.

Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies.

Zuchero YJ, Chen X, Bien-Ly N, Bumbaca D, Tong RK, Gao X, Zhang S, Hoyte K, Luk W, Huntley MA, Phu L, Tan C, Kallop D, Weimer RM, Lu Y, Kirkpatrick DS, Ernst JA, Chih B, Dennis MS, Watts RJ.

Neuron. 2016 Jan 6;89(1):70-82. doi: 10.1016/j.neuron.2015.11.024. Epub 2015 Dec 10.

29.

Association of Kidney Graft Loss With De Novo Produced Donor-Specific and Non-Donor-Specific HLA Antibodies Detected by Single Antigen Testing.

Süsal C, Wettstein D, Döhler B, Morath C, Ruhenstroth A, Scherer S, Tran TH, Gombos P, Schemmer P, Wagner E, Fehr T, Živčić-Ćosić S, Balen S, Weimer R, Slavcev A, Bösmüller C, Norman DJ, Zeier M, Opelz G; Collaborative Transplant Study Report.

Transplantation. 2015 Sep;99(9):1976-80. doi: 10.1097/TP.0000000000000672.

PMID:
25769065
30.

Helicobacter pylori interferes with leukocyte migration via the outer membrane protein HopQ and via CagA translocation.

Busch B, Weimer R, Woischke C, Fischer W, Haas R.

Int J Med Microbiol. 2015 May;305(3):355-64. doi: 10.1016/j.ijmm.2015.02.003. Epub 2015 Feb 14.

PMID:
25736449
31.

The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.

Astarita JL, Cremasco V, Fu J, Darnell MC, Peck JR, Nieves-Bonilla JM, Song K, Kondo Y, Woodruff MC, Gogineni A, Onder L, Ludewig B, Weimer RM, Carroll MC, Mooney DJ, Xia L, Turley SJ.

Nat Immunol. 2015 Jan;16(1):75-84. doi: 10.1038/ni.3035. Epub 2014 Oct 27.

32.

Activity-induced Nr4a1 regulates spine density and distribution pattern of excitatory synapses in pyramidal neurons.

Chen Y, Wang Y, Ertürk A, Kallop D, Jiang Z, Weimer RM, Kaminker J, Sheng M.

Neuron. 2014 Jul 16;83(2):431-443. doi: 10.1016/j.neuron.2014.05.027. Epub 2014 Jun 26.

33.

Chronic GluN2B antagonism disrupts behavior in wild-type mice without protecting against synapse loss or memory impairment in Alzheimer's disease mouse models.

Hanson JE, Meilandt WJ, Gogineni A, Reynen P, Herrington J, Weimer RM, Scearce-Levie K, Zhou Q.

J Neurosci. 2014 Jun 11;34(24):8277-88. doi: 10.1523/JNEUROSCI.5106-13.2014.

34.

Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase.

Olsen O, Kallop DY, McLaughlin T, Huntwork-Rodriguez S, Wu Z, Duggan CD, Simon DJ, Lu Y, Easley-Neal C, Takeda K, Hass PE, Jaworski A, O'Leary DD, Weimer RM, Tessier-Lavigne M.

J Neurosci. 2014 May 7;34(19):6438-47. doi: 10.1523/JNEUROSCI.3522-13.2014.

35.

A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.

Kallop DY, Meilandt WJ, Gogineni A, Easley-Neal C, Wu T, Jubb AM, Yaylaoglu M, Shamloo M, Tessier-Lavigne M, Scearce-Levie K, Weimer RM.

J Neurosci. 2014 May 7;34(19):6425-37. doi: 10.1523/JNEUROSCI.4963-13.2014.

36.

Axons degenerate in the absence of mitochondria in C. elegans.

Rawson RL, Yam L, Weimer RM, Bend EG, Hartwieg E, Horvitz HR, Clark SG, Jorgensen EM.

Curr Biol. 2014 Mar 31;24(7):760-5. doi: 10.1016/j.cub.2014.02.025. Epub 2014 Mar 13.

37.

ATG induction in renal transplant recipients: Long-term hazard of severe infection is associated with long-term functional T cell impairment but not the ATG-induced CD4 cell decline.

Weimer R, Ettrich M, Renner F, Dietrich H, Süsal C, Deisz S, Padberg W, Opelz G.

Hum Immunol. 2014 Jun;75(6):561-9. doi: 10.1016/j.humimm.2014.02.015. Epub 2014 Feb 12.

PMID:
24530759
38.

Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants.

Bien-Ly N, Yu YJ, Bumbaca D, Elstrott J, Boswell CA, Zhang Y, Luk W, Lu Y, Dennis MS, Weimer RM, Chung I, Watts RJ.

J Exp Med. 2014 Feb 10;211(2):233-44. doi: 10.1084/jem.20131660. Epub 2014 Jan 27.

39.

Regulation of axon degeneration after injury and in development by the endogenous calpain inhibitor calpastatin.

Yang J, Weimer RM, Kallop D, Olsen O, Wu Z, Renier N, Uryu K, Tessier-Lavigne M.

Neuron. 2013 Dec 4;80(5):1175-89. doi: 10.1016/j.neuron.2013.08.034. Epub 2013 Nov 7.

40.

Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.

Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, Weimer RM, Kirkpatrick DS, Lewcock JW.

J Exp Med. 2013 Nov 18;210(12):2553-67. doi: 10.1084/jem.20122832. Epub 2013 Oct 28.

41.

An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins.

Hazen M, Bhakta S, Vij R, Randle S, Kallop D, Chiang V, Hötzel I, Jaiswal BS, Ervin KE, Li B, Weimer RM, Polakis P, Scheller RH, Junutula JR, Hongo JA.

MAbs. 2014 Jan-Feb;6(1):95-107.

42.

Analysis of lipsticks using Raman spectroscopy.

Gardner P, Bertino MF, Weimer R, Hazelrigg E.

Forensic Sci Int. 2013 Oct 10;232(1-3):67-72. doi: 10.1016/j.forsciint.2013.07.007. Epub 2013 Aug 7.

PMID:
24053867
43.

Rotigotine polyoxazoline conjugate SER-214 provides robust and sustained antiparkinsonian benefit.

Eskow Jaunarajs KL, Standaert DG, Viegas TX, Bentley MD, Fang Z, Dizman B, Yoon K, Weimer R, Ravenscroft P, Johnston TH, Hill MP, Brotchie JM, Moreadith RW.

Mov Disord. 2013 Oct;28(12):1675-82. doi: 10.1002/mds.25625. Epub 2013 Sep 3.

44.

Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis.

Gogineni A, Caunt M, Crow A, Lee CV, Fuh G, van Bruggen N, Ye W, Weimer RM.

PLoS One. 2013 Jul 16;8(7):e68755. doi: 10.1371/journal.pone.0068755. Print 2013.

45.

The risk of polyomavirus-associated graft nephropathy is increased by a combined suppression of CD8 and CD4 cell-dependent immune effects.

Renner FC, Dietrich H, Bulut N, Celik D, Freitag E, Gaertner N, Karoui S, Mark J, Raatz C, Weimer R, Feustel A.

Transplant Proc. 2013 May;45(4):1608-10. doi: 10.1016/j.transproceed.2013.01.026.

PMID:
23726630
46.

A caspase cascade regulating developmental axon degeneration.

Simon DJ, Weimer RM, McLaughlin T, Kallop D, Stanger K, Yang J, O'Leary DD, Hannoush RN, Tessier-Lavigne M.

J Neurosci. 2012 Dec 5;32(49):17540-53. doi: 10.1523/JNEUROSCI.3012-12.2012.

47.

Spatially coordinated kinase signaling regulates local axon degeneration.

Chen M, Maloney JA, Kallop DY, Atwal JK, Tam SJ, Baer K, Kissel H, Kaminker JS, Lewcock JW, Weimer RM, Watts RJ.

J Neurosci. 2012 Sep 26;32(39):13439-53.

48.

Proapoptotic activation of death receptor 5 on tumor endothelial cells disrupts the vasculature and reduces tumor growth.

Wilson NS, Yang A, Yang B, Couto S, Stern H, Gogineni A, Pitti R, Marsters S, Weimer RM, Singh M, Ashkenazi A.

Cancer Cell. 2012 Jul 10;22(1):80-90. doi: 10.1016/j.ccr.2012.05.014.

49.

An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.

Adolfsson O, Pihlgren M, Toni N, Varisco Y, Buccarello AL, Antoniello K, Lohmann S, Piorkowska K, Gafner V, Atwal JK, Maloney J, Chen M, Gogineni A, Weimer RM, Mortensen DL, Friesenhahn M, Ho C, Paul R, Pfeifer A, Muhs A, Watts RJ.

J Neurosci. 2012 Jul 11;32(28):9677-89. doi: 10.1523/JNEUROSCI.4742-11.2012.

50.

Imaging synaptic protein dynamics using photoactivatable green fluorescent protein.

Weimer RM, Hill TC, Hamilton AM, Zito K.

Cold Spring Harb Protoc. 2012 Jul 1;2012(7):771-7. doi: 10.1101/pdb.prot070029.

PMID:
22753605

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