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Items: 6

1.

'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase.

Heikal A, Nakatani Y, Jiao W, Wilson C, Rennison D, Weimar MR, Parker EJ, Brimble MA, Cook GM.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2239-2243. doi: 10.1016/j.bmcl.2018.05.048. Epub 2018 May 26.

PMID:
29859905
2.

Development of Multiwell-Plate Methods Using Pure Cultures of Methanogens To Identify New Inhibitors for Suppressing Ruminant Methane Emissions.

Weimar MR, Cheung J, Dey D, McSweeney C, Morrison M, Kobayashi Y, Whitman WB, Carbone V, Schofield LR, Ronimus RS, Cook GM.

Appl Environ Microbiol. 2017 Jul 17;83(15). pii: e00396-17. doi: 10.1128/AEM.00396-17. Print 2017 Aug 1.

3.

Oral Bacitracin: A Consideration for Suppression of Intestinal Vancomycin-Resistant Enterococci (VRE) and for VRE Bacteremia From an Apparent Gastrointestinal Tract Source.

Tran TT, Palmer HR, Weimar MR, Arias CA, Cook GM, Murray BE.

Clin Infect Dis. 2015 Jun 1;60(11):1726-8. doi: 10.1093/cid/civ130. Epub 2015 Feb 19. No abstract available.

4.

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation.

Heikal A, Nakatani Y, Dunn E, Weimar MR, Day CL, Baker EN, Lott JS, Sazanov LA, Cook GM.

Mol Microbiol. 2014 Mar;91(5):950-64. doi: 10.1111/mmi.12507. Epub 2014 Jan 21.

5.

Identification and characterization of a bacitracin resistance network in Enterococcus faecalis.

Gebhard S, Fang C, Shaaly A, Leslie DJ, Weimar MR, Kalamorz F, Carne A, Cook GM.

Antimicrob Agents Chemother. 2014;58(3):1425-33. doi: 10.1128/AAC.02111-13. Epub 2013 Dec 16.

6.

Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia.

Berney M, Weimar MR, Heikal A, Cook GM.

Mol Microbiol. 2012 May;84(4):664-81. doi: 10.1111/j.1365-2958.2012.08053.x. Epub 2012 Apr 16.

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