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A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9.

Garcia J, Flood VH, Haberichter SL, Fahs SA, Mattson JG, Geurts AM, Zogg M, Weiler H, Shi Q, Montgomery RR.

Res Pract Thromb Haemost. 2019 Dec 29;4(1):64-71. doi: 10.1002/rth2.12280. eCollection 2020 Jan.


The severe spontaneous bleeding phenotype in a novel hemophilia A rat model is rescued by platelet FVIII expression.

Shi Q, Mattson JG, Fahs SA, Geurts AM, Weiler H, Montgomery RR.

Blood Adv. 2020 Jan 14;4(1):55-65. doi: 10.1182/bloodadvances.2019000944.


The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis.

Fields B, DeLaForest A, Zogg M, May J, Hagen C, Komnick K, Wieser J, Lundberg A, Weiler H, Battle MA, Carlson KS.

Sci Rep. 2019 Dec 17;9(1):19303. doi: 10.1038/s41598-019-55844-x.


Role of thrombomodulin expression on hematopoietic stem cells.

Basu S, Liang HPH, Hernandez I, Zogg M, Fields B, May J, Ogoti Y, Wyseure T, Mosnier LO, Burns RT, Carlson K, Weiler H.

J Thromb Haemost. 2020 Jan;18(1):123-135. doi: 10.1111/jth.14663. Epub 2019 Nov 6.


Fermented Milk Products and Bone Health in Postmenopausal Women: A Systematic Review of Randomized Controlled Trials, Prospective Cohorts, and Case-Control Studies.

Ong AM, Kang K, Weiler HA, Morin SN.

Adv Nutr. 2019 Oct 11. pii: nmz108. doi: 10.1093/advances/nmz108. [Epub ahead of print]


Myeloid cell-synthesized coagulation factor X dampens antitumor immunity.

Graf C, Wilgenbus P, Pagel S, Pott J, Marini F, Reyda S, Kitano M, Macher-Göppinger S, Weiler H, Ruf W.

Sci Immunol. 2019 Sep 20;4(39). pii: eaaw8405. doi: 10.1126/sciimmunol.aaw8405.


Arachidonic acid exacerbates diet-induced obesity and reduces bone mineral content without impacting bone strength in growing male rats.

Mak IL, Lavery P, Agellon S, Rauch F, Murshed M, Weiler HA.

J Nutr Biochem. 2019 Nov;73:108226. doi: 10.1016/j.jnutbio.2019.108226. Epub 2019 Aug 15.


Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice.

Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q.

Blood Adv. 2019 Sep 24;3(18):2700-2711. doi: 10.1182/bloodadvances.2019000516.


Lean body mass accretion is elevated in response to dietary vitamin D: A dose-response study in female weanling rats.

Razaghi M, Djekic-Ivankovic M, Agellon S, Mak I, Lavery P, Weiler HA.

Nutr Res. 2019 Aug;68:92-100. doi: 10.1016/j.nutres.2019.07.004. Epub 2019 Jul 30.


Maternal and neonatal red blood cell n-3 polyunsaturated fatty acids inversely associate with infant whole body fat mass assessed by dual-energy x-ray absorptiometry.

Farahnak Z, Yuan Y, Vanstone CA, Weiler HA.

Appl Physiol Nutr Metab. 2019 Aug 22. doi: 10.1139/apnm-2019-0311. [Epub ahead of print]


Ethnicity and Immigration Status as Risk Factors for Gestational Diabetes Mellitus, Anemia and Pregnancy Outcomes Among Food Insecure Women Attending the Montreal Diet Dispensary Program.

Ménard V, Sotunde OF, Weiler HA.

Can J Diabetes. 2019 May 17. pii: S1499-2671(18)30707-X. doi: 10.1016/j.jcjd.2019.05.004. [Epub ahead of print]


Evaluation of plasma and erythrocyte fatty acids C15:0, t-C16:1n-7 and C17:0 as biomarkers of dairy fat consumption in adolescents.

Slim M, Ha C, Vanstone CA, Morin SN, Rahme E, Weiler HA.

Prostaglandins Leukot Essent Fatty Acids. 2019 Oct;149:24-29. doi: 10.1016/j.plefa.2019.07.007. Epub 2019 Jul 3.


The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability.

Gandhi DM, Rosas R Jr, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C.

Bioorg Med Chem. 2019 Sep 1;27(17):3788-3796. doi: 10.1016/j.bmc.2019.06.043. Epub 2019 Jun 29.


Arachidonic acid status negatively associates with forearm bone outcomes and glucose homeostasis in children with an overweight condition or obesity.

Mak IL, Cohen TR, Vanstone CA, Weiler HA.

Appl Physiol Nutr Metab. 2019 Jul 3:1-9. doi: 10.1139/apnm-2019-0046. [Epub ahead of print]


A Direct Comparison of Self-Expandable Portico Versus Balloon-Expandable Sapien 3 Devices for Transcatheter Aortic Valve Replacement: A Case-Matched Cohort Study.

Mas-Peiro S, Seppelt PC, Weiler H, Mohr GL, Papadopoulos N, Walther T, Zeiher AM, Fichtlscherer S, Vasa-Nicotera M.

J Invasive Cardiol. 2019 Jul;31(7):E199-E204.


[Out-of-hospital airway management with a laryngeal tube or endotracheal intubation for out-of-hospital cardiac arrest : Influence on in-hospital mortality].

Erath JW, Reichert A, Büttner S, Weiler H, Vamos M, von Jeinsen B, Heyl S, Schalk R, Mutlak H, Zeiher AM, Fichtlscherer S, Honold J.

Med Klin Intensivmed Notfmed. 2019 Jun 13. doi: 10.1007/s00063-019-0588-1. [Epub ahead of print] German.


Litter quality and microtopography as key drivers to topsoil properties and understorey plant diversity in ancient broadleaved forests on decalcified marl.

Kooijman AM, Weiler HA, Cusell C, Anders N, Meng X, Seijmonsbergen AC, Cammeraat LH.

Sci Total Environ. 2019 Sep 20;684:113-125. doi: 10.1016/j.scitotenv.2019.05.285. Epub 2019 May 21.


Dietary docosahexaenoic acid contributes to increased bone mineral accretion and strength in young female Sprague-Dawley rats.

Farahnak Z, Freundorfer MT, Lavery P, Weiler HA.

Prostaglandins Leukot Essent Fatty Acids. 2019 May;144:32-39. doi: 10.1016/j.plefa.2019.04.005. Epub 2019 Apr 22.


Aortic valve replacement in patients with preexisting liver disease: Transfemoral approach with favorable survival.

Seppelt PC, Zappel J, Weiler H, Mas-Peiró S, Papadopoulos N, Walther T, Zeiher AM, Fichtlscherer S, Vasa-Nicotera M.

Catheter Cardiovasc Interv. 2020 Jan;95(1):54-64. doi: 10.1002/ccd.28319. Epub 2019 Apr 29.


Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus.

Natour NA, Morin SN, Egeland GM, Weiler HA.

Int J Circumpolar Health. 2019 Dec;78(1):1601056. doi: 10.1080/22423982.2019.1601056.


Maternal risk factors and newborn infant vitamin D status: a scoping literature review.

Sotunde OF, Laliberte A, Weiler HA.

Nutr Res. 2019 Mar;63:1-20. doi: 10.1016/j.nutres.2018.11.011. Epub 2018 Dec 7. Review.


Docosahexaenoic Acid at 0.4% of Dietary Weight Enhances Lean Mass in Young Female Sprague-Dawley Rats.

Farahnak Z, Lévy-Ndejuru J, Lavery P, Weiler HA.

J Nutr. 2019 Mar 1;149(3):479-487. doi: 10.1093/jn/nxy266.


Defective collagen binding and increased bleeding in a murine model of von Willebrand disease affecting collagen IV binding.

Slobodianuk TL, Kochelek C, Foeckler J, Kalloway S, Weiler H, Flood VH.

J Thromb Haemost. 2019 Jan;17(1):63-71. doi: 10.1111/jth.14341. Epub 2018 Dec 18.


Comparison of interventional and surgical myocardial revascularization in kidney transplant recipients - A single-centre retrospective analysis.

Lang J, Buettner S, Weiler H, Papadopoulos N, Geiger H, Hauser I, Vasa-Nicotera M, Zeiher A, Fichtlscherer S, Honold J.

Int J Cardiol Heart Vasc. 2018 Nov 4;21:96-102. doi: 10.1016/j.ijcha.2018.10.010. eCollection 2018 Dec.


High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (PlA1).

Zhi H, Ahlen MT, Thinn AMM, Weiler H, Curtis BR, Skogen B, Zhu J, Newman PJ.

Blood Adv. 2018 Nov 13;2(21):3001-3011. doi: 10.1182/bloodadvances.2018023341.


Regional adiposity and markers of inflammation in pre-school age children.

Delaney KZ, Vanstone CA, Weiler HA, Santosa S.

Sci Rep. 2018 Oct 12;8(1):15204. doi: 10.1038/s41598-018-33054-1.


Post/preprocedural ratio of hemodynamically assessed aortic regurgitation index as a marker for the need for corrective measures during transcatheter valve replacement: A first confirmatory study in patients receiving a new generation transcatheter self-expandable prosthesis.

Mas-Peiro S, Weiler H, Papadopoulos N, Zeiher AM, Fichtlscherer S, Vasa-Nicotera M.

Catheter Cardiovasc Interv. 2019 Feb 15;93(3):532-537. doi: 10.1002/ccd.27847. Epub 2018 Sep 30.


Normative Data for Lean Mass and Fat Mass in Healthy Predominantly Breast-Fed Term Infants From 1 Month to 1 Year of Age.

Sotunde OF, Gallo S, Vanstone CA, Weiler HA.

J Clin Densitom. 2018 Jul 19. pii: S1094-6950(18)30082-9. doi: 10.1016/j.jocd.2018.07.004. [Epub ahead of print]


Reply to T Sugiyama.

Brett NR, Weiler HA.

Am J Clin Nutr. 2018 Oct 1;108(4):898. doi: 10.1093/ajcn/nqy156. No abstract available.


Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis.

Bergmeier W, Antoniak S, Conway EM, Denis CV, George LA, Isermann B, Key NS, Krishnaswamy S, Lam WA, Lillicrap D, Liu J, Looney MR, López JA, Maas C, Peyvandi F, Ruf W, Sood AK, Versteeg HH, Wolberg AS, Wong PC, Wood JP, Weiler H.

Res Pract Thromb Haemost. 2018 Apr 12;2(3):407-428. doi: 10.1002/rth2.12095. eCollection 2018 Jul. Review.


Red blood cell folate levels in Canadian Inuit women of childbearing years: influence of food security, body mass index, smoking, education, and vitamin use.

Duncan K, Erickson AC, Egeland GM, Weiler H, Arbour LT.

Can J Public Health. 2018 Dec;109(5-6):684-691. doi: 10.17269/s41997-018-0085-y. Epub 2018 May 9.


Vitamin D Status and Immune Health Outcomes in a Cross-Sectional Study and a Randomized Trial of Healthy Young Children.

Brett NR, Lavery P, Agellon S, Vanstone CA, Goruk S, Field CJ, Weiler HA.

Nutrients. 2018 May 27;10(6). pii: E680. doi: 10.3390/nu10060680.


Association Between Vitamin D Supplementation During Pregnancy and Offspring Growth, Morbidity, and Mortality: A Systematic Review and Meta-analysis.

Bi WG, Nuyt AM, Weiler H, Leduc L, Santamaria C, Wei SQ.

JAMA Pediatr. 2018 Jul 1;172(7):635-645. doi: 10.1001/jamapediatrics.2018.0302.


Benefits and safety of dietary protein for bone health-an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation.

Rizzoli R, Biver E, Bonjour JP, Coxam V, Goltzman D, Kanis JA, Lappe J, Rejnmark L, Sahni S, Weaver C, Weiler H, Reginster JY.

Osteoporos Int. 2018 Sep;29(9):1933-1948. doi: 10.1007/s00198-018-4534-5. Epub 2018 May 8. Review.


Vitamin D status and functional health outcomes in children aged 2-8 y: a 6-mo vitamin D randomized controlled trial.

Brett NR, Parks CA, Lavery P, Agellon S, Vanstone CA, Kaufmann M, Jones G, Maguire JL, Rauch F, Weiler HA.

Am J Clin Nutr. 2018 Mar 1;107(3):355-364. doi: 10.1093/ajcn/nqx062.


Vitamin D status and intake of lactating Inuit women living in the Canadian Arctic.

El Hayek Fares J, Weiler HA.

Public Health Nutr. 2018 Aug;21(11):1988-1994. doi: 10.1017/S1368980017004189. Epub 2018 Feb 13.


Changes in eating behavior and plasma leptin in children with obesity participating in a family-centered lifestyle intervention.

Cohen TR, Hazell TJ, Vanstone CA, Rodd C, Weiler HA.

Appetite. 2018 Jun 1;125:81-89. doi: 10.1016/j.appet.2018.01.017. Epub 2018 Feb 2.


Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study).

McNally D, Amrein K, O'Hearn K, Fergusson D, Geier P, Henderson M, Khamessan A, Lawson ML, McIntyre L, Redpath S, Weiler HA, Menon K; Canadian Critical Care Trials Group.

Pilot Feasibility Stud. 2017 Dec 8;3:70. doi: 10.1186/s40814-017-0214-z. eCollection 2017.


Thirty-Day Outcomes in 100 Consecutive Patients Undergoing Transfemoral Aortic Valve Replacement With the Portico Valve on an All-Comer Basis.

Mas-Peiro S, Vasa-Nicotera M, Weiler H, Papadopoulos N, De Rosa R, Zeiher AM, Fichtlscherer S.

J Invasive Cardiol. 2017 Dec;29(12):431-436.


Factor V Leiden is associated with increased sperm count.

van Mens TE, Joensen UN, Bochdanovits Z, Takizawa A, Peter J, Jørgensen N, Szecsi PB, Meijers JCM, Weiler H, Rajpert-De Meyts E, Repping S, Middeldorp S.

Hum Reprod. 2017 Nov 1;32(11):2332-2339. doi: 10.1093/humrep/dex287.


Variable phenotypic penetrance of thrombosis in adult mice after tissue-selective and temporally controlled Thbd gene inactivation.

van Mens TE, Liang HH, Basu S, Hernandez I, Zogg M, May J, Zhan M, Yang Q, Foeckler J, Kalloway S, Sood R, Karlson CS, Weiler H.

Blood Adv. 2017 Jun 27;1(15):1148-1158. doi: 10.1182/bloodadvances.2017005058. Epub 2017 Jun 23.


DHA and EPA in red blood cell membranes are associated with dietary intakes of omega-3-rich fish in healthy children.

Parks CA, Brett NR, Agellon S, Lavery P, Vanstone CA, Maguire JL, Rauch F, Weiler HA.

Prostaglandins Leukot Essent Fatty Acids. 2017 Sep;124:11-16. doi: 10.1016/j.plefa.2017.08.003. Epub 2017 Aug 14.


Bone Health is Maintained, While Fat Mass is Reduced in Pre-pubertal Children with Obesity Participating in a 1-Year Family-Centered Lifestyle Intervention.

Cohen TR, Hazell TJ, Vanstone CA, Rodd C, Weiler HA.

Calcif Tissue Int. 2017 Dec;101(6):612-622. doi: 10.1007/s00223-017-0318-8. Epub 2017 Sep 2.


A 51-item calcium-focused food frequency questionnaire is a reliable tool to assess dietary calcium intake in postmenopausal women.

Ong AM, Weiler HA, Wall M, Goltzman D, Whiting SJ, Daskalopoulou SS, Morin SN.

Nutr Res. 2017 Jul;43:33-42. doi: 10.1016/j.nutres.2017.05.006. Epub 2017 May 18.


Thrombin promotes diet-induced obesity through fibrin-driven inflammation.

Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ.

J Clin Invest. 2017 Aug 1;127(8):3152-3166. doi: 10.1172/JCI92744. Epub 2017 Jul 24.


Associations between omega-3 fatty acids and 25(OH)D and psychological distress among Inuit in Canada.

Skogli HR, Geoffroy D, Weiler HA, Tell GS, Kirmayer LJ, Egeland GM.

Int J Circumpolar Health. 2017;76(1):1302684. doi: 10.1080/22423982.2017.1302684.


TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice.

Haribhai D, Luo X, Chen J, Jia S, Shi L, Schroeder JA, Weiler H, Aster RH, Hessner MJ, Hu J, Williams CB, Shi Q.

Blood Adv. 2016 Dec 13;1(2):139-151. doi: 10.1182/bloodadvances.2016001453.


Diet diversity, growth and adiposity in healthy breastfed infants fed homemade complementary foods.

Mok E, Vanstone CA, Gallo S, Li P, Constantin E, Weiler HA.

Int J Obes (Lond). 2017 May;41(5):776-782. doi: 10.1038/ijo.2017.37. Epub 2017 Feb 6.


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