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Individual- versus group-optimality in the production of secreted bacterial compounds.

Schiessl KT, Ross-Gillespie A, Cornforth DM, Weigert M, Bigosch C, Brown SP, Ackermann M, Küemmerli R.

Evolution. 2019 Feb 21. doi: 10.1111/evo.13701. [Epub ahead of print]


SPHK1 Is a Novel Target of Metformin in Ovarian Cancer.

Hart PC, Chiyoda T, Liu X, Weigert M, Curtis M, Chiang CY, Loth R, Lastra R, McGregor SM, Locasale JW, Lengyel E, Romero IL.

Mol Cancer Res. 2019 Jan 17. doi: 10.1158/1541-7786.MCR-18-0409. [Epub ahead of print]


Content-aware image restoration: pushing the limits of fluorescence microscopy.

Weigert M, Schmidt U, Boothe T, Müller A, Dibrov A, Jain A, Wilhelm B, Schmidt D, Broaddus C, Culley S, Rocha-Martins M, Segovia-Miranda F, Norden C, Henriques R, Zerial M, Solimena M, Rink J, Tomancak P, Royer L, Jug F, Myers EW.

Nat Methods. 2018 Dec;15(12):1090-1097. doi: 10.1038/s41592-018-0216-7. Epub 2018 Nov 26.


Probing the evolutionary robustness of two repurposed drugs targeting iron uptake in Pseudomonas aeruginosa.

Rezzoagli C, Wilson D, Weigert M, Wyder S, Kümmerli R.

Evol Med Public Health. 2018 Sep 10;2018(1):246-259. doi: 10.1093/emph/eoy026. eCollection 2018.


Differential lateral and basal tension drive folding of Drosophila wing discs through two distinct mechanisms.

Sui L, Alt S, Weigert M, Dye N, Eaton S, Jug F, Myers EW, Jülicher F, Salbreux G, Dahmann C.

Nat Commun. 2018 Nov 5;9(1):4620. doi: 10.1038/s41467-018-06497-3.


The influence of body composition on exercise-associated skin temperature changes after resistance training.

Weigert M, Nitzsche N, Kunert F, Lösch C, Schulz H.

J Therm Biol. 2018 Jul;75:112-119. doi: 10.1016/j.jtherbio.2018.05.009. Epub 2018 Jun 2.


The bacterium Pseudomonas aeruginosa senses and gradually responds to interspecific competition for iron.

Leinweber A, Weigert M, Kümmerli R.

Evolution. 2018 Apr 17. doi: 10.1111/evo.13491. [Epub ahead of print]


Biobeam-Multiplexed wave-optical simulations of light-sheet microscopy.

Weigert M, Subramanian K, Bundschuh ST, Myers EW, Kreysing M.

PLoS Comput Biol. 2018 Apr 13;14(4):e1006079. doi: 10.1371/journal.pcbi.1006079. eCollection 2018 Apr.


Active matrix metalloproteinase-8 and periodontal bacteria-interlink between periodontitis and inflammatory bowel disease?

Schmidt J, Weigert M, Leuschner C, Hartmann H, Raddatz D, Haak R, Mausberg RF, Kottmann T, Schmalz G, Ziebolz D.

J Periodontol. 2018 Jun;89(6):699-707. doi: 10.1002/JPER.17-0486.


Origins and specificity of auto-antibodies in Sm+ SLE patients.

Kalinina O, Louzoun Y, Wang Y, Utset T, Weigert M.

J Autoimmun. 2018 Jun;90:94-104. doi: 10.1016/j.jaut.2018.02.008. Epub 2018 Mar 1.


RIPK3 promotes adenovirus type 5 activity.

Weigert M, Binks A, Dowson S, Leung EYL, Athineos D, Yu X, Mullin M, Walton JB, Orange C, Ennis D, Blyth K, Tait SWG, McNeish IA.

Cell Death Dis. 2017 Dec 13;8(12):3206. doi: 10.1038/s41419-017-0110-8.


The physical boundaries of public goods cooperation between surface-attached bacterial cells.

Weigert M, Kümmerli R.

Proc Biol Sci. 2017 Jul 12;284(1858). pii: 20170631. doi: 10.1098/rspb.2017.0631.


Manipulating virulence factor availability can have complex consequences for infections.

Weigert M, Ross-Gillespie A, Leinweber A, Pessi G, Brown SP, Kümmerli R.

Evol Appl. 2016 Oct 24;10(1):91-101. doi: 10.1111/eva.12431. eCollection 2017 Jan.


Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance.

Perera J, Zheng Z, Li S, Gudjonson H, Kalinina O, Benichou JIC, Block KE, Louzoun Y, Yin D, Chong AS, Dinner AR, Weigert M, Huang H.

Cell Rep. 2016 Oct 4;17(2):387-398. doi: 10.1016/j.celrep.2016.09.011.


Two- and three-dimensional co-culture models of soft tissue healing: pericyte-endothelial cell interaction.

Jennewein M, Bubel M, Guthörl S, Metzger W, Weigert M, Pohlemann T, Oberringer M.

Cell Tissue Res. 2016 Aug;365(2):279-93. doi: 10.1007/s00441-016-2391-0. Epub 2016 Mar 30.


A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S.

Cell. 2015 Aug 27;162(5):1066-77. doi: 10.1016/j.cell.2015.07.047.


ClearVolume: open-source live 3D visualization for light-sheet microscopy.

Royer LA, Weigert M, Günther U, Maghelli N, Jug F, Sbalzarini IF, Myers EW.

Nat Methods. 2015 Jun;12(6):480-1. doi: 10.1038/nmeth.3372. No abstract available.


Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.

Preuss KD, Pfreundschuh M, Weigert M, Fadle N, Regitz E, Kubuschok B.

J Clin Invest. 2015 May;125(5):2179. doi: 10.1172/JCI82091. Epub 2015 May 1. No abstract available.


Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.

Preuss KD, Pfreundschuh M, Weigert M, Fadle N, Regitz E, Kubuschok B.

J Clin Invest. 2015 Jan;125(1):316-23. doi: 10.1172/JCI76802. Epub 2014 Dec 8. Erratum in: J Clin Invest. 2015 May;125(5):2179. Weigert, Martin [Added].


Paternal diet defines offspring chromatin state and intergenerational obesity.

Öst A, Lempradl A, Casas E, Weigert M, Tiko T, Deniz M, Pantano L, Boenisch U, Itskov PM, Stoeckius M, Ruf M, Rajewsky N, Reuter G, Iovino N, Ribeiro C, Alenius M, Heyne S, Vavouri T, Pospisilik JA.

Cell. 2014 Dec 4;159(6):1352-64. doi: 10.1016/j.cell.2014.11.005.


Gallium-mediated siderophore quenching as an evolutionarily robust antibacterial treatment.

Ross-Gillespie A, Weigert M, Brown SP, Kümmerli R.

Evol Med Public Health. 2014 Jan;2014(1):18-29. doi: 10.1093/emph/eou003. Epub 2014 Jan 30.


Light chain editors of anti-DNA receptors in human B cells.

Kalinina O, Wang Y, Sia K, Radic M, Cazenave PA, Weigert M.

J Exp Med. 2014 Feb 10;211(2):357-64. doi: 10.1084/jem.20122340. Epub 2014 Jan 27.


Antibodies that bind complex glycosaminoglycans accumulate in the Golgi.

Radic M, Weigert MG, Khan SN, Han J, Kalinina O, Luning Prak ET.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11958-63. doi: 10.1073/pnas.1308620110. Epub 2013 Jul 1.


Impact of conization type on the resected cone volume: results of a retrospective multi-center study.

Grimm C, Brammen L, Sliutz G, Weigert M, Sevelda P, Pils S, Reinthaller A, Polterauer S.

Arch Gynecol Obstet. 2013 Nov;288(5):1081-6. doi: 10.1007/s00404-013-2873-1. Epub 2013 May 7.


Does duration of hysteroscopy increase the risk of disease recurrence in patients with endometrial cancer? A multi-centre trial.

Tempfer C, Froese G, Buerkle B, Polterauer S, Grimm C, Concin N, Hofstetter G, Weigert M, Oehler MK.

Exp Ther Med. 2011 Sep;2(5):991-995. Epub 2011 Jun 30.


Apoptotic marginal zone deletion of anti-Sm/ribonucleoprotein B cells.

Kishi Y, Higuchi T, Phoon S, Sakamaki Y, Kamiya K, Riemekasten G, Akiyoshi K, Weigert MG, Tsubata T.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7811-6. doi: 10.1073/pnas.1204509109. Epub 2012 Apr 30.


B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients.

Schoettler N, Ni D, Weigert M.

Mol Immunol. 2012 Jul;51(3-4):273-82. doi: 10.1016/j.molimm.2012.03.028. Epub 2012 Apr 18.


Model for competition from self during passive immunization, with application to broadly neutralizing antibodies for HIV.

Ali Tabei SM, Li Y, Weigert M, Dinner AR.

Vaccine. 2012 Jan 11;30(3):607-13. doi: 10.1016/j.vaccine.2011.11.048. Epub 2011 Nov 23.


Intra-Golgi formation of IgM-glycosaminoglycan complexes promotes Ig deposition.

Khan SN, Cox JV, Nishimoto SK, Chen C, Fritzler MJ, Hendershot LM, Weigert M, Radic M.

J Immunol. 2011 Sep 15;187(6):3198-207. doi: 10.4049/jimmunol.1101336. Epub 2011 Aug 12.


Selection of individual VH genes occurs at the pro-B to pre-B cell transition.

Meng W, Yunk L, Wang LS, Maganty A, Xue E, Cohen PL, Eisenberg RA, Weigert MG, Mancini SJ, Prak ET.

J Immunol. 2011 Aug 15;187(4):1835-44. doi: 10.4049/jimmunol.1100207. Epub 2011 Jul 11.


Alternative mechanisms of receptor editing in autoreactive B cells.

Kalinina O, Doyle-Cooper CM, Miksanek J, Meng W, Prak EL, Weigert MG.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7125-30. doi: 10.1073/pnas.1019389108. Epub 2011 Apr 6.


Receptor editing: an approach by autoreactive B cells to escape tolerance. The Journal of Experimental Medicine. 1993. 177: 999-1008.

Gay D, Saunders T, Camper S, Weigert M.

J Immunol. 2011 Feb 1;186(3):1303-12. No abstract available.


In-silico cell surface modeling reveals mechanism for initial steps of B-cell receptor signal transduction.

Nudelman G, Weigert M, Louzoun Y.

Mol Immunol. 2009 Sep;46(15):3141-50. doi: 10.1016/j.molimm.2009.03.027. Epub 2009 Jul 23.


Erythropoetin beta twice weekly versus standard therapy in patients with gynaecological malignancies--a randomised Austrian AGO trial.

Volgger B, Petru E, Angleitner-Boubenizek L, Weigert M, Reinthaller A, Lass H, Stempfl A, Gamper C, Deibl M, Marth C.

Anticancer Res. 2008 Nov-Dec;28(6B):3977-84.


Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in in vitro fertilization-embryo transfer patients.

Weigert M, Gruber D, Pernicka E, Bauer P, Feichtinger W.

J Assist Reprod Genet. 2009 Jan;26(1):13-7. doi: 10.1007/s10815-008-9278-2. Epub 2008 Nov 20.


Whole-body PET/CT imaging: combining software- and hardware-based co-registration.

Weigert M, Pietrzyk U, Müller S, Palm C, Beyer T.

Z Med Phys. 2008;18(1):59-66.


Editing and escape from editing in anti-DNA B cells.

Khan SN, Witsch EJ, Goodman NG, Panigrahi AK, Chen C, Jiang Y, Cline AM, Erikson J, Weigert M, Prak ET, Radic M.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3861-6. doi: 10.1073/pnas.0800025105. Epub 2008 Feb 29.


MR-based attenuation correction for torso-PET/MR imaging: pitfalls in mapping MR to CT data.

Beyer T, Weigert M, Quick HH, Pietrzyk U, Vogt F, Palm C, Antoch G, Müller SP, Bockisch A.

Eur J Nucl Med Mol Imaging. 2008 Jun;35(6):1142-6. doi: 10.1007/s00259-008-0734-0. Epub 2008 Feb 19.


Reflections on the clonal-selection theory.

Cohn M, Mitchison NA, Paul WE, Silverstein AM, Talmage DW, Weigert M.

Nat Rev Immunol. 2007 Oct;7(10):823-30. Review.


Automatic analysis of immunofluorescence patterns of HEp-2 cells.

Hiemann R, Hilger N, Michel J, Nitschke J, Böhm A, Anderer U, Weigert M, Sack U.

Ann N Y Acad Sci. 2007 Aug;1109:358-71.


Lupus susceptibility genes may breach tolerance to DNA by impairing receptor editing of nuclear antigen-reactive B cells.

Liu Y, Li L, Kumar KR, Xie C, Lightfoot S, Zhou XJ, Kearney JF, Weigert M, Mohan C.

J Immunol. 2007 Jul 15;179(2):1340-52.


Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.

Doyle CM, Han J, Weigert MG, Prak ET.

Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11264-9. Epub 2006 Jul 17.


Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction.

Witsch EJ, Cao H, Fukuyama H, Weigert M.

J Exp Med. 2006 Jul 10;203(7):1761-72. Epub 2006 Jun 26.


Development and selection of edited B cells in B6.56R mice.

Sekiguchi DR, Yunk L, Gary D, Charan D, Srivastava B, Allman D, Weigert MG, Prak ET.

J Immunol. 2006 Jun 1;176(11):6879-87.


Selection of anti-double-stranded DNA B cells in autoimmune MRL-lpr/lpr mice.

Chen C, Li H, Tian Q, Beardall M, Xu Y, Casanova N, Weigert M.

J Immunol. 2006 May 1;176(9):5183-90.


Investigation of 208 consecutive cases of cervical cone biopsies with regard to indication, negative samples and quality control.

Weigl G, Pokieser W, Schuller B, Weigert M, Ulrich W, Sevelda P, Breitenecker G.

Acta Cytol. 2006 Mar-Apr;50(2):185-90.


Objective quality evaluation of fluorescence images to optimize automatic image acquisition.

Hiemann R, Hilger N, Sack U, Weigert M.

Cytometry A. 2006 Mar;69(3):182-4.


Control of genotypic allelic inclusion through TCR surface expression.

Warmflash A, Weigert M, Dinner AR.

J Immunol. 2005 Nov 15;175(10):6412-9.


T-cell epitope repertoire as predicted from human and viral genomes.

Louzoun Y, Vider T, Weigert M.

Mol Immunol. 2006 Feb;43(6):559-69. Epub 2005 May 31.


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