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Items: 1 to 50 of 179

1.

Organoid single-cell genomic atlas uncovers human-specific features of brain development.

Kanton S, Boyle MJ, He Z, Santel M, Weigert A, Sanchís-Calleja F, Guijarro P, Sidow L, Fleck JS, Han D, Qian Z, Heide M, Huttner WB, Khaitovich P, Pääbo S, Treutlein B, Camp JG.

Nature. 2019 Oct;574(7778):418-422. doi: 10.1038/s41586-019-1654-9. Epub 2019 Oct 16.

PMID:
31619793
2.

Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development.

Elwakeel E, Brüggemann M, Fink AF, Schulz MH, Schmid T, Savai R, Brüne B, Zarnack K, Weigert A.

Int J Mol Sci. 2019 Sep 9;20(18). pii: E4438. doi: 10.3390/ijms20184438.

3.

Sphingosine-1-Phosphate and Macrophage Biology-How the Sphinx Tames the Big Eater.

Weigert A, Olesch C, Brüne B.

Front Immunol. 2019 Jul 19;10:1706. doi: 10.3389/fimmu.2019.01706. eCollection 2019. Review.

4.

Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation.

Syed SN, Raue R, Weigert A, von Knethen A, Brüne B.

Cells. 2019 Jul 28;8(8). pii: E785. doi: 10.3390/cells8080785.

5.

Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.

Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, de Silva K, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I.

EMBO J. 2019 Sep 2;38(17):e100938. doi: 10.15252/embj.2018100938. Epub 2019 Jul 22.

PMID:
31328803
6.

Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis.

Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E3005. doi: 10.3390/ijms20123005.

7.

Orellanus syndrome - an unusual case of mushroom poisoning with acute kidney injury in Portugal.

Luz IA, Querido S, Lopes K, Carvalho F, Weigert A, Adragão T, Lobos AV.

Clin Nephrol. 2019 Sep;92(3):162-164. doi: 10.5414/CN109771. No abstract available.

PMID:
31198172
8.

The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NFκB-Dependent Manner.

Helfinger V, Palfi K, Weigert A, Schröder K.

Oxid Med Cell Longev. 2019 Apr 18;2019:3264858. doi: 10.1155/2019/3264858. eCollection 2019.

9.

HVEM, a cosignaling molecular switch, and its interactions with BTLA, CD160 and LIGHT.

Rodriguez-Barbosa JI, Schneider P, Weigert A, Lee KM, Kim TJ, Perez-Simon JA, Del Rio ML.

Cell Mol Immunol. 2019 Jul;16(7):679-682. doi: 10.1038/s41423-019-0241-1. Epub 2019 Jun 3. No abstract available.

PMID:
31160757
10.

Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation.

Weigert A, von Knethen A, Thomas D, Faria I, Namgaladze D, Zezina E, Fuhrmann D, Petcherski A, Heringdorf DMZ, Radeke HH, Brüne B.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Sep;1864(9):1235-1246. doi: 10.1016/j.bbalip.2019.05.008. Epub 2019 May 23.

11.

PGE2 in fibrosis and cancer: Insights into fibroblast activation.

Elwakeel E, Brüne B, Weigert A.

Prostaglandins Other Lipid Mediat. 2019 Aug;143:106339. doi: 10.1016/j.prostaglandins.2019.106339. Epub 2019 May 14. Review.

PMID:
31100473
12.

Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis.

von Knethen A, Schäfer A, Kuchler L, Knape T, Christen U, Hintermann E, Fißlthaler B, Schröder K, Brandes RP, Genz B, Abshagen K, Pützer BM, Sha LK, Weigert A, Syed SN, Schulz M, Shah AM, Ernst A, Putyrski M, Finkelmeier F, Pesic M, Greten F, Hogardt M, Kempf VAJ, Gunne S, Parnham MJ, Brüne B.

Theranostics. 2019 Mar 16;9(7):2003-2016. doi: 10.7150/thno.28057. eCollection 2019.

13.

IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells.

Han Y, Mora J, Huard A, da Silva P, Wiechmann S, Putyrski M, Schuster C, Elwakeel E, Lang G, Scholz A, Scholz T, Schmid T, de Bruin N, Billuart P, Sala C, Burkhardt H, Parnham MJ, Ernst A, Brüne B, Weigert A.

Cell Rep. 2019 Apr 16;27(3):835-846.e5. doi: 10.1016/j.celrep.2019.03.082.

14.

The polarity protein Scrib limits atherosclerosis development in mice.

Schürmann C, Dienst FL, Pálfi K, Vasconez AE, Oo JA, Wang S, Buchmann GK, Offermanns S, van de Sluis B, Leisegang MS, Günther S, Humbert PO, Lee E, Zhu J, Weigert A, Mathoor P, Wittig I, Kruse C, Brandes RP.

Cardiovasc Res. 2019 Apr 5. pii: cvz093. doi: 10.1093/cvr/cvz093. [Epub ahead of print]

PMID:
30949676
15.

IL-22 and IL-22-Binding Protein Are Associated With Development of and Mortality From Acute-on-Chronic Liver Failure.

Schwarzkopf K, Rüschenbaum S, Barat S, Cai C, Mücke MM, Fitting D, Weigert A, Brüne B, Zeuzem S, Welsch C, Lange CM.

Hepatol Commun. 2019 Jan 17;3(3):392-405. doi: 10.1002/hep4.1303. eCollection 2019 Mar.

16.

Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype.

Frank AC, Ebersberger S, Fink AF, Lampe S, Weigert A, Schmid T, Ebersberger I, Syed SN, Brüne B.

Nat Commun. 2019 Mar 8;10(1):1135. doi: 10.1038/s41467-019-08989-2.

17.

Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase.

Schwiebs A, Herrero San Juan M, Schmidt KG, Wiercinska E, Anlauf M, Ottenlinger F, Thomas D, Elwakeel E, Weigert A, Farin HF, Bonig H, Scholich K, Geisslinger G, Pfeilschifter JM, Radeke HH.

Oncogene. 2019 Jun;38(24):4788-4803. doi: 10.1038/s41388-019-0758-x. Epub 2019 Feb 28.

PMID:
30816345
18.

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.

Leisegang MS, Gu L, Preussner J, Günther S, Hitzel J, Ratiu C, Weigert A, Chen W, Schwarz EC, Looso M, Fork C, Brandes RP.

FEBS Lett. 2019 Mar;593(5):487-498. doi: 10.1002/1873-3468.13337. Epub 2019 Feb 27.

PMID:
30758047
19.

Achievement of renal anemia KDIGO targets by two different clinical strategies - a European hemodialysis multicenter analysis.

Drozdz M, Weigert A, Silva F, Frazão J, Alsuwaida A, Krishnan M, Kleophas W, Brzosko S, Johansson FK, Jacobson SH.

BMC Nephrol. 2019 Jan 7;20(1):5. doi: 10.1186/s12882-018-1196-7.

20.

Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation.

Winslow S, Scholz A, Rappl P, Brauß TF, Mertens C, Jung M, Weigert A, Brüne B, Schmid T.

PLoS One. 2019 Jan 7;14(1):e0209694. doi: 10.1371/journal.pone.0209694. eCollection 2019.

21.

Novel therapeutic approaches in primary hyperoxaluria.

Weigert A, Martin-Higueras C, Hoppe B.

Expert Opin Emerg Drugs. 2018 Dec;23(4):349-357. doi: 10.1080/14728214.2018.1552940. Epub 2018 Dec 12. Review.

PMID:
30540923
22.

Divergent evolution in the genomes of closely related lacertids, Lacerta viridis and L. bilineata, and implications for speciation.

Kolora SRR, Weigert A, Saffari A, Kehr S, Walter Costa MB, Spröer C, Indrischek H, Chintalapati M, Lohse K, Doose G, Overmann J, Bunk B, Bleidorn C, Grimm-Seyfarth A, Henle K, Nowick K, Faria R, Stadler PF, Schlegel M.

Gigascience. 2019 Feb 1;8(2). pii: giy160. doi: 10.1093/gigascience/giy160.

23.

The impact of functioning hemodialysis arteriovenous accesses on renal graft perfusion: Results of a pilot study.

Laranjinha I, Matias P, Oliveira R, Casqueiro A, Bento MT, Carvalho AP, Adragão T, Jorge C, Bruges M, Birne R, Machado D, Weigert A.

J Vasc Access. 2019 Sep;20(5):482-487. doi: 10.1177/1129729818817248. Epub 2018 Dec 6.

PMID:
30520327
24.

Congenital intrahepatic portocaval shunts and hypoglycemia due to secondary hyperinsulinism: a case report and review of the literature.

Weigert A, Bierwolf J, Reutter H, Gembruch U, Woelfle J, Ganschow R, Mueller A.

J Med Case Rep. 2018 Nov 12;12(1):336. doi: 10.1186/s13256-018-1881-y. Review.

25.

Rewards to increase living kidney donation: The state of the art.

Querido S, Weigert A, Adragão T, Machado D, Pais D.

Nefrologia. 2019 Jan - Feb;39(1):11-14. doi: 10.1016/j.nefro.2018.08.003. Epub 2018 Nov 1. English, Spanish. No abstract available.

26.

The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue.

Kern K, Schäfer SMG, Cohnen J, Pierre S, Osthues T, Tarighi N, Hohmann S, Ferreiros N, Brüne B, Weigert A, Geisslinger G, Sisignano M, Scholich K.

Front Immunol. 2018 Oct 1;9:2261. doi: 10.3389/fimmu.2018.02261. eCollection 2018.

27.

Risk of hepatitis B reactivation in hepatitis B surface antigen seronegative and core antibody seropositive kidney transplant recipients.

Querido S, Weigert A, Adragão T, Rodrigues L, Jorge C, Bruges M, Machado D.

Transpl Infect Dis. 2019 Feb;21(1):e13009. doi: 10.1111/tid.13009. Epub 2018 Nov 5.

PMID:
30295412
28.

IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors.

Gupta S, Jain A, Syed SN, Snodgrass RG, Pflüger-Müller B, Leisegang MS, Weigert A, Brandes RP, Ebersberger I, Brüne B, Namgaladze D.

Oncoimmunology. 2018 Jul 30;7(10):e1494110. doi: 10.1080/2162402X.2018.1494110. eCollection 2018.

29.

Convergent evolution of the ladder-like ventral nerve cord in Annelida.

Helm C, Beckers P, Bartolomaeus T, Drukewitz SH, Kourtesis I, Weigert A, Purschke G, Worsaae K, Struck TH, Bleidorn C.

Front Zool. 2018 Sep 27;15:36. doi: 10.1186/s12983-018-0280-y. eCollection 2018.

30.

The portal vein as a distinct immunological compartment - A comprehensive immune phenotyping study.

Queck A, Rueschenbaum S, Kubesch A, Cai C, Zeuzem S, Weigert A, Brüne B, Nour-Eldin NA, Gruber-Rouh T, Vogl T, Lange CM.

Hum Immunol. 2018 Oct;79(10):716-723. doi: 10.1016/j.humimm.2018.07.233. Epub 2018 Jul 30.

PMID:
30071249
31.

An in vitro test system for compounds that modulate human inflammatory macrophage polarization.

Shiratori H, Feinweber C, Luckhardt S, Wallner N, Geisslinger G, Weigert A, Parnham MJ.

Eur J Pharmacol. 2018 Aug 15;833:328-338. doi: 10.1016/j.ejphar.2018.06.017. Epub 2018 Jun 18.

PMID:
29920284
32.

NoxO1 Controls Proliferation of Colon Epithelial Cells.

Moll F, Walter M, Rezende F, Helfinger V, Vasconez E, De Oliveira T, Greten FR, Olesch C, Weigert A, Radeke HH, Schröder K.

Front Immunol. 2018 May 8;9:973. doi: 10.3389/fimmu.2018.00973. eCollection 2018.

33.

mPGES-1 and ALOX5/-15 in tumor-associated macrophages.

Weigert A, Strack E, Snodgrass RG, Brüne B.

Cancer Metastasis Rev. 2018 Sep;37(2-3):317-334. doi: 10.1007/s10555-018-9731-3. Review.

PMID:
29808459
34.

The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2-mediated neuropathic pain induced by mechanical nerve damage.

Treutlein EM, Kern K, Weigert A, Tarighi N, Schuh CD, Nüsing RM, Schreiber Y, Ferreirós N, Brüne B, Geisslinger G, Pierre S, Scholich K.

J Biol Chem. 2018 Jun 22;293(25):9685-9695. doi: 10.1074/jbc.RA118.002492. Epub 2018 May 11.

35.

Nephrolithiasis and Nephrocalcinosis in Childhood-Risk Factor-Related Current and Future Treatment Options.

Weigert A, Hoppe B.

Front Pediatr. 2018 Apr 12;6:98. doi: 10.3389/fped.2018.00098. eCollection 2018. Review.

36.

A classic twin study of lower urinary tract obstruction: Report of 3 cases and literature review.

Frese S, Weigert A, Hoppe B, Feldkötter M, Ludwig M, Weber S, Kiliś-Pstrusińska K, Zaniew M, Reutter H, Hilger AC.

Low Urin Tract Symptoms. 2019 Apr;11(2):O85-O88. doi: 10.1111/luts.12222. Epub 2018 Apr 17.

PMID:
29664229
37.

Hepatitis C Virus Eradication in Kidney Transplant Recipients: A Single-Center Experience in Portugal.

Weigert A, Querido S, Carvalho L, Lebre L, Chagas C, Matias P, Birne R, Nascimento C, Jorge C, Adragão T, Bruges M, Machado D.

Transplant Proc. 2018 Apr;50(3):743-745. doi: 10.1016/j.transproceed.2018.02.017.

PMID:
29661427
38.

Intravenous Immunoglobulin and Rituximab in HLA Highly Sensitized Kidney Transplant Recipients.

Querido S, Weigert A, Adragão T, Henriques J, Birne R, Matias P, Jorge C, Nascimento C, Bruges M, Machado D.

Transplant Proc. 2018 Apr;50(3):723-727. doi: 10.1016/j.transproceed.2018.02.016.

PMID:
29661424
39.

[Letter to the Editor. Use of Vitamin K Antagonists in Patients on Hemodialysis: Is Benefit Greater than the Risk?]

Godinho I, Weigert A.

Acta Med Port. 2018 Jan 31;31(1):69-70. doi: 10.20344/amp.9800. Epub 2018 Jan 31. Portuguese. No abstract available.

40.

Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma.

Sekar D, Govene L, Del Río ML, Sirait-Fischer E, Fink AF, Brüne B, Rodriguez-Barbosa JI, Weigert A.

Int J Mol Sci. 2018 Mar 7;19(3). pii: E752. doi: 10.3390/ijms19030752.

41.

VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia.

Laban H, Weigert A, Zink J, Elgheznawy A, Schürmann C, Günther L, Abdel Malik R, Bothur S, Wingert S, Bremer R, Rieger MA, Brüne B, Brandes RP, Fleming I, Benz PM.

J Cell Biol. 2018 Apr 2;217(4):1503-1519. doi: 10.1083/jcb.201702048. Epub 2018 Mar 5.

42.

Selective targeting of tumor associated macrophages in different tumor models.

Kakoschky B, Pleli T, Schmithals C, Zeuzem S, Brüne B, Vogl TJ, Korf HW, Weigert A, Piiper A.

PLoS One. 2018 Feb 15;13(2):e0193015. doi: 10.1371/journal.pone.0193015. eCollection 2018.

43.

Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment.

Mertens C, Mora J, Ören B, Grein S, Winslow S, Scholich K, Weigert A, Malmström P, Forsare C, Fernö M, Schmid T, Brüne B, Jung M.

Oncoimmunology. 2017 Dec 22;7(3):e1408751. doi: 10.1080/2162402X.2017.1408751. eCollection 2018.

44.

Redox-signals and macrophage biology.

Weigert A, von Knethen A, Fuhrmann D, Dehne N, Brüne B.

Mol Aspects Med. 2018 Oct;63:70-87. doi: 10.1016/j.mam.2018.01.003. Epub 2018 Jan 12. Review.

PMID:
29329794
45.

Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages.

Ringleb J, Strack E, Angioni C, Geisslinger G, Steinhilber D, Weigert A, Brüne B.

J Immunol. 2018 Jan 15;200(2):857-868. doi: 10.4049/jimmunol.1700609. Epub 2017 Dec 11.

46.

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice.

Rezende F, Moll F, Walter M, Helfinger V, Hahner F, Janetzko P, Ringel C, Weigert A, Fleming I, Weissmann N, Kuenne C, Looso M, Rieger MA, Nawroth P, Fleming T, Brandes RP, Schröder K.

Redox Biol. 2018 May;15:12-21. doi: 10.1016/j.redox.2017.11.014. Epub 2017 Nov 22.

47.

Multiple brown tumors - a rare presentation in the modern era
.

Rodrigues N, Godinho I, Leite Nogueira E, Jorge S, López-Presa D, Gomes da Costa A, Weigert AL.

Clin Nephrol. 2018 Jan;89 (2018)(1):57-60. doi: 10.5414/CN109135.

PMID:
29189198
48.

Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.

Pullamsetti SS, Kojonazarov B, Storn S, Gall H, Salazar Y, Wolf J, Weigert A, El-Nikhely N, Ghofrani HA, Krombach GA, Fink L, Gattenlöhner S, Rapp UR, Schermuly RT, Grimminger F, Seeger W, Savai R.

Sci Transl Med. 2017 Nov 15;9(416). pii: eaai9048. doi: 10.1126/scitranslmed.aai9048.

PMID:
29141888
49.

IGA nephropathy - Are intravenous steroid pulses more effective than oral steroids in relapse prevention?

Laranjinha I, Matias P, Cassis J, Branco P, Ramos S, Barata JD, Weigert A.

Nefrologia. 2018 Jul - Aug;38(4):355-360. doi: 10.1016/j.nefro.2017.08.004. Epub 2017 Nov 10. English, Spanish.

50.

Iron Handling in Tumor-Associated Macrophages-Is There a New Role for Lipocalin-2?

Jung M, Weigert A, Mertens C, Rehwald C, Brüne B.

Front Immunol. 2017 Sep 20;8:1171. doi: 10.3389/fimmu.2017.01171. eCollection 2017. Review.

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