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Items: 1 to 50 of 63

1.

β1D-integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment.

Soto-Ribeiro M, Kastberger B, Bachmann M, Azizi L, Jacquier MC, Boettiger D, Bouvard D, Bastmeyer M, Hytönen VP, Wehrle-Haller B.

J Cell Sci. 2019 Mar 19. pii: jcs.224493. doi: 10.1242/jcs.224493. [Epub ahead of print]

PMID:
30890648
2.

Simultaneous Study of the Recruitment of Monocyte Subpopulations Under Flow In Vitro.

Ropraz P, Imhof BA, Matthes T, Wehrle-Haller B, Sidibé A.

J Vis Exp. 2018 Nov 26;(141). doi: 10.3791/58509.

PMID:
30531721
3.

β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin.

Sabra H, Brunner M, Mandati V, Wehrle-Haller B, Lallemand D, Ribba AS, Chevalier G, Guardiola P, Block MR, Bouvard D.

J Biol Chem. 2017 Nov 24;292(47):19179-19197. doi: 10.1074/jbc.M117.808063. Epub 2017 Sep 29.

4.

Mechanical stability of talin rod controls cell migration and substrate sensing.

Rahikainen R, von Essen M, Schaefer M, Qi L, Azizi L, Kelly C, Ihalainen TO, Wehrle-Haller B, Bastmeyer M, Huang C, Hytönen VP.

Sci Rep. 2017 Jun 15;7(1):3571. doi: 10.1038/s41598-017-03335-2.

5.

Role and impact of the extracellular matrix on integrin-mediated pancreatic β-cell functions.

Arous C, Wehrle-Haller B.

Biol Cell. 2017 Jun;109(6):223-237. doi: 10.1111/boc.201600076. Epub 2017 Apr 18. Review.

PMID:
28266044
6.

TiN x O y coatings facilitate the initial adhesion of osteoblasts to create a suitable environment for their proliferation and the recruitment of endothelial cells.

Moussa M, Banakh O, Wehrle-Haller B, Fontana P, Scherrer S, Cattani M, Wiskott A, Durual S.

Biomed Mater. 2017 Feb 28;12(2):025001. doi: 10.1088/1748-605X/aa57a7.

PMID:
28244429
7.

Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrix.

Egervari K, Potter G, Guzman-Hernandez ML, Salmon P, Soto-Ribeiro M, Kastberger B, Balla T, Wehrle-Haller B, Kiss JZ.

Glia. 2016 Mar;64(3):440-56. doi: 10.1002/glia.22939. Epub 2015 Nov 5.

PMID:
26539695
8.

Mechanosensing in cell-matrix adhesions - Converting tension into chemical signals.

Hytönen VP, Wehrle-Haller B.

Exp Cell Res. 2016 Apr 10;343(1):35-41. doi: 10.1016/j.yexcr.2015.10.027. Epub 2015 Oct 27. Review.

PMID:
26518118
9.

Cytoplasmic methylation fuels leukocyte invasion.

Wehrle-Haller B.

Nat Immunol. 2015 May;16(5):441-3. doi: 10.1038/ni.3142. No abstract available.

PMID:
25898189
10.

Preface. Brain extracellular matrix in health and disease.

Dityatev A, Wehrle-Haller B, Pitkänen A.

Prog Brain Res. 2014;214:xiii-xvii. doi: 10.1016/B978-0-444-63486-3.09998-9. No abstract available.

PMID:
25410369
11.

Intracellular signaling and perception of neuronal scaffold through integrins and their adapter proteins.

Wehrle-Haller B, Bastmeyer M.

Prog Brain Res. 2014;214:443-60. doi: 10.1016/B978-0-444-63486-3.00018-9. Review.

PMID:
25410368
12.

Plasticity of the actin cytoskeleton in response to extracellular matrix nanostructure and dimensionality.

Starke J, Wehrle-Haller B, Friedl P.

Biochem Soc Trans. 2014 Oct;42(5):1356-66. doi: 10.1042/BST20140139.

PMID:
25233415
13.

Maturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractions.

Hu W, Wehrle-Haller B, Vogel V.

PLoS One. 2014 Sep 17;9(9):e107097. doi: 10.1371/journal.pone.0107097. eCollection 2014.

14.

Niche anchorage and signaling through membrane-bound Kit-ligand/c-kit receptor are kinase independent and imatinib insensitive.

Tabone-Eglinger S, Calderin-Sollet Z, Pinon P, Aebischer N, Wehrle-Haller M, Jacquier MC, Boettiger D, Wehrle-Haller B.

FASEB J. 2014 Oct;28(10):4441-56. doi: 10.1096/fj.14-249425. Epub 2014 Jul 7.

PMID:
25002122
15.

Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing.

Pinon P, Pärssinen J, Vazquez P, Bachmann M, Rahikainen R, Jacquier MC, Azizi L, Määttä JA, Bastmeyer M, Hytönen VP, Wehrle-Haller B.

J Cell Biol. 2014 Apr 28;205(2):265-81. doi: 10.1083/jcb.201308136.

16.

Protein conformation as a regulator of cell-matrix adhesion.

Hytönen VP, Wehrle-Haller B.

Phys Chem Chem Phys. 2014 Apr 14;16(14):6342-57. doi: 10.1039/c3cp54884h. Epub 2014 Jan 28.

PMID:
24469063
17.

Peripheral blood CD56(bright) NK cells respond to stem cell factor and adhere to its membrane-bound form after upregulation of c-kit.

Pradier A, Tabone-Eglinger S, Huber V, Bosshard C, Rigal E, Wehrle-Haller B, Roosnek E.

Eur J Immunol. 2014 Feb;44(2):511-20. doi: 10.1002/eji.201343868. Epub 2013 Nov 20.

18.

Mechanotransduction of mesenchymal melanoma cell invasion into 3D collagen lattices: filopod-mediated extension-relaxation cycles and force anisotropy.

Starke J, Maaser K, Wehrle-Haller B, Friedl P.

Exp Cell Res. 2013 Oct 1;319(16):2424-33. doi: 10.1016/j.yexcr.2013.04.003. Epub 2013 Jul 2.

PMID:
23830878
19.

A highly specific gold nanoprobe for live-cell single-molecule imaging.

Leduc C, Si S, Gautier J, Soto-Ribeiro M, Wehrle-Haller B, Gautreau A, Giannone G, Cognet L, Lounis B.

Nano Lett. 2013 Apr 10;13(4):1489-94. doi: 10.1021/nl304561g. Epub 2013 Mar 6.

PMID:
23458263
20.

Assembly and disassembly of cell matrix adhesions.

Wehrle-Haller B.

Curr Opin Cell Biol. 2012 Oct;24(5):569-81. doi: 10.1016/j.ceb.2012.06.010. Epub 2012 Jul 19. Review.

PMID:
22819514
21.

Membrane-bound Kit ligand regulates melanocyte adhesion and survival, providing physical interaction with an intraepithelial niche.

Tabone-Eglinger S, Wehrle-Haller M, Aebischer N, Jacquier MC, Wehrle-Haller B.

FASEB J. 2012 Sep;26(9):3738-53. doi: 10.1096/fj.12-206045. Epub 2012 May 25.

PMID:
22637532
22.

Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion.

Rondas D, Tomas A, Soto-Ribeiro M, Wehrle-Haller B, Halban PA.

J Biol Chem. 2012 Jan 20;287(4):2423-36. doi: 10.1074/jbc.M111.279885. Epub 2011 Dec 2.

23.

Structure and function of focal adhesions.

Wehrle-Haller B.

Curr Opin Cell Biol. 2012 Feb;24(1):116-24. doi: 10.1016/j.ceb.2011.11.001. Epub 2011 Dec 2. Review.

PMID:
22138388
24.

Integrin and glycocalyx mediated contributions to cell adhesion identified by single cell force spectroscopy.

Boettiger D, Wehrle-Haller B.

J Phys Condens Matter. 2010 May 19;22(19):194101. doi: 10.1088/0953-8984/22/19/194101. Epub 2010 Apr 26.

PMID:
21386430
25.

Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation.

Pinon P, Wehrle-Haller B.

Pigment Cell Melanoma Res. 2011 Apr;24(2):282-94. doi: 10.1111/j.1755-148X.2010.00806.x. Epub 2010 Dec 9. Review.

PMID:
21087420
26.

New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering.

Saltel F, Mortier E, Hytönen VP, Jacquier MC, Zimmermann P, Vogel V, Liu W, Wehrle-Haller B.

J Cell Biol. 2009 Nov 30;187(5):715-31. doi: 10.1083/jcb.200908134. Epub 2009 Nov 23.

27.

Dimerization of Kit-ligand and efficient cell-surface presentation requires a conserved Ser-Gly-Gly-Tyr motif in its transmembrane domain.

Paulhe F, Wehrle-Haller M, Jacquier MC, Imhof BA, Tabone-Eglinger S, Wehrle-Haller B.

FASEB J. 2009 Sep;23(9):3037-48. doi: 10.1096/fj.09-129577. Epub 2009 Apr 22.

PMID:
19386768
28.

Multiscale modeling of form and function.

Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM.

Science. 2009 Apr 10;324(5924):208-12. doi: 10.1126/science.1170107. Review.

29.

Cell-matrix adhesion complexes: master control machinery of cell migration.

Lock JG, Wehrle-Haller B, Strömblad S.

Semin Cancer Biol. 2008 Feb;18(1):65-76. Epub 2007 Oct 6. Review.

PMID:
18023204
30.

Urokinase receptor (CD87) clustering in detergent-insoluble adhesion patches leads to cell adhesion independently of integrins.

Petzinger J, Saltel F, Hersemeyer K, Daniel JM, Preissner KT, Wehrle-Haller B, Kanse SM.

Cell Commun Adhes. 2007 Oct;14(4):137-55.

PMID:
17957530
31.

CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts.

Chabadel A, Bañon-Rodríguez I, Cluet D, Rudkin BB, Wehrle-Haller B, Genot E, Jurdic P, Anton IM, Saltel F.

Mol Biol Cell. 2007 Dec;18(12):4899-910. Epub 2007 Sep 26.

32.

Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis.

Gauthier BR, Duhamel DL, Iezzi M, Theander S, Saltel F, Fukuda M, Wehrle-Haller B, Wollheim CB.

FASEB J. 2008 Jan;22(1):194-206. Epub 2007 Aug 20.

PMID:
17709608
33.

Analysis of integrin dynamics by fluorescence recovery after photobleaching.

Wehrle-Haller B.

Methods Mol Biol. 2007;370:173-202.

PMID:
17416995
34.

An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features.

Cornillon S, Gebbie L, Benghezal M, Nair P, Keller S, Wehrle-Haller B, Charette SJ, Brückert F, Letourneur F, Cosson P.

EMBO Rep. 2006 Jun;7(6):617-21. Epub 2006 May 12.

35.

The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells.

Cluzel C, Saltel F, Lussi J, Paulhe F, Imhof BA, Wehrle-Haller B.

J Cell Biol. 2005 Oct 24;171(2):383-92.

36.

Intracellular interleukin-1 receptor antagonist type 1 antagonizes the stimulatory effect of interleukin-1 alpha precursor on cell motility.

Merhi-Soussi F, Berti M, Wehrle-Haller B, Gabay C.

Cytokine. 2005 Nov 3;32(3-4):163-70. Epub 2005 Oct 24.

PMID:
16246569
37.

Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function.

Marthinet E, Bloc A, Oka Y, Tanizawa Y, Wehrle-Haller B, Bancila V, Dubuis JM, Philippe J, Schwitzgebel VM.

J Clin Endocrinol Metab. 2005 Sep;90(9):5401-6. Epub 2005 Jul 5.

PMID:
15998776
38.

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.

Angelillo-Scherrer A, Burnier L, Flores N, Savi P, DeMol M, Schaeffer P, Herbert JM, Lemke G, Goff SP, Matsushima GK, Earp HS, Vesin C, Hoylaerts MF, Plaisance S, Collen D, Conway EM, Wehrle-Haller B, Carmeliet P.

J Clin Invest. 2005 Feb;115(2):237-46.

39.

A specific endoplasmic reticulum export signal drives transport of stem cell factor (Kitl) to the cell surface.

Paulhe F, Imhof BA, Wehrle-Haller B.

J Biol Chem. 2004 Dec 31;279(53):55545-55. Epub 2004 Oct 8.

40.

Cell behaviour on micropatterned substrata: limits of extracellular matrix geometry for spreading and adhesion.

Lehnert D, Wehrle-Haller B, David C, Weiland U, Ballestrem C, Imhof BA, Bastmeyer M.

J Cell Sci. 2004 Jan 1;117(Pt 1):41-52.

41.

Integrin-dependent pathologies.

Wehrle-Haller B, Imhof BA.

J Pathol. 2003 Jul;200(4):481-7. Review.

PMID:
12845615
42.

Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts.

Hinz B, Dugina V, Ballestrem C, Wehrle-Haller B, Chaponnier C.

Mol Biol Cell. 2003 Jun;14(6):2508-19. Epub 2003 Feb 21.

43.

The role of Kit-ligand in melanocyte development and epidermal homeostasis.

Wehrle-Haller B.

Pigment Cell Res. 2003 Jun;16(3):287-96. Review.

PMID:
12753403
44.

Actin, microtubules and focal adhesion dynamics during cell migration.

Wehrle-Haller B, Imhof BA.

Int J Biochem Cell Biol. 2003 Jan;35(1):39-50. Review.

PMID:
12467646
45.

Molecular identification of distinct neurogenic and melanogenic neural crest sublineages.

Luo R, Gao J, Wehrle-Haller B, Henion PD.

Development. 2003 Jan;130(2):321-30.

46.

The inner lives of focal adhesions.

Wehrle-Haller B, Imhof B.

Trends Cell Biol. 2002 Aug;12(8):382-9. Review.

PMID:
12191915
47.

Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior.

Ballestrem C, Hinz B, Imhof BA, Wehrle-Haller B.

J Cell Biol. 2001 Dec 24;155(7):1319-32. Epub 2001 Dec 24.

49.

Stem cell factor presentation to c-Kit. Identification of a basolateral targeting domain.

Wehrle-Haller B, Imhof BA.

J Biol Chem. 2001 Apr 20;276(16):12667-74. Epub 2001 Jan 10.

50.

PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis.

Wong CW, Wiedle G, Ballestrem C, Wehrle-Haller B, Etteldorf S, Bruckner M, Engelhardt B, Gisler RH, Imhof BA.

Mol Biol Cell. 2000 Sep;11(9):3109-21.

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