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Items: 1 to 50 of 133

1.

Acetylcholine-stimulated [3H]GABA release from mouse brain synaptosomes is modulated by alpha4beta2 and alpha4alpha5beta2 nicotinic receptor subtypes.

McClure-Begley TD, King NM, Collins AC, Stitzel JA, Wehner JM, Butt CM.

Mol Pharmacol. 2009 Apr;75(4):918-26. doi: 10.1124/mol.108.052274. Epub 2009 Jan 12.

2.

Cued and contextual fear conditioning in mice.

Wehner JM, Radcliffe RA.

Curr Protoc Neurosci. 2004 Sep;Chapter 8:Unit 8.5C. doi: 10.1002/0471142301.ns0805cs27.

PMID:
18428608
3.

Decreased anxiety-like behavior in beta3 nicotinic receptor subunit knockout mice.

Booker TK, Butt CM, Wehner JM, Heinemann SF, Collins AC.

Pharmacol Biochem Behav. 2007 May;87(1):146-57. Epub 2007 Apr 21.

PMID:
17509676
4.

The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition.

Schlaepfer IR, Clegg HV, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Krauter K, Lessem J, Rhee SH, Stallings MC, Wehner JM, Young SE, Ehringer MA.

Addict Biol. 2007 Jun;12(2):200-9.

PMID:
17508994
5.

Microarray analysis identifies cerebellar genes sensitive to chronic ethanol treatment in PKCgamma mice.

Bowers BJ, Radcliffe RA, Smith AM, Miyamoto-Ditmon J, Wehner JM.

Alcohol. 2006 Aug;40(1):19-33.

6.

Regulation of 5-HT2A/C receptors and DOI-induced behaviors by protein kinase Cgamma.

Bowers BJ, Miyamoto-Ditmon J, Wehner JM.

Pharmacol Biochem Behav. 2006 Oct;85(2):441-7. Epub 2006 Nov 15.

7.

Guidelines on nicotine dose selection for in vivo research.

Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, Lukas RJ, Markou A, Marks MJ, McCallum SE, Parameswaran N, Perkins KA, Picciotto MR, Quik M, Rose JE, Rothenfluh A, Schafer WR, Stolerman IP, Tyndale RF, Wehner JM, Zirger JM.

Psychopharmacology (Berl). 2007 Feb;190(3):269-319. Epub 2006 Aug 9. Review.

PMID:
16896961
8.

Microarray analysis of the effects of a gamma-protein kinase C null mutation on gene expression in striatum: a role for transthyretin in mutant phenotypes.

Smith AM, Bowers BJ, Radcliffe RA, Wehner JM.

Behav Genet. 2006 Nov;36(6):869-81. Epub 2006 Jun 10.

PMID:
16767509
9.

The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice.

Kelso ML, Wehner JM, Collins AC, Scheff SW, Pauly JR.

Brain Res. 2006 Apr 14;1083(1):204-10. Epub 2006 Mar 20.

PMID:
16545784
10.

Performance of alpha7 nicotinic receptor null mutants is impaired in appetitive learning measured in a signaled nose poke task.

Keller JJ, Keller AB, Bowers BJ, Wehner JM.

Behav Brain Res. 2005 Jul 1;162(1):143-52. Epub 2005 Apr 13.

PMID:
15922075
11.

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

Bowers BJ, McClure-Begley TD, Keller JJ, Paylor R, Collins AC, Wehner JM.

Alcohol Clin Exp Res. 2005 Mar;29(3):295-302.

PMID:
15770102
12.

Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning.

Wehner JM, Keller JJ, Keller AB, Picciotto MR, Paylor R, Booker TK, Beaudet A, Heinemann SF, Balogh SA.

Neuroscience. 2004;129(1):11-24.

PMID:
15489024
13.

Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response.

Owens JC, Balogh SA, McClure-Begley TD, Butt CM, Labarca C, Lester HA, Picciotto MR, Wehner JM, Collins AC.

Alcohol Clin Exp Res. 2003 Dec;27(12):1867-75.

PMID:
14691373
14.

Open field activity and EtOH activation of gamma-PKC null mutants.

Hix DM, Bowers BJ, Miyamoto JH, Wehner JM.

Addict Biol. 2003 Dec;8(4):399-412.

PMID:
14690876
15.

Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.

Lester HA, Fonck C, Tapper AR, McKinney S, Damaj MI, Balogh S, Owens J, Wehner JM, Collins AC, Labarca C.

Curr Opin Drug Discov Devel. 2003 Sep;6(5):633-9. Review.

PMID:
14579512
16.

Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice.

Gorski JA, Balogh SA, Wehner JM, Jones KR.

Neuroscience. 2003;121(2):341-54.

PMID:
14521993
17.

Fine scale mapping of a genetic locus for conditioned fear.

Talbot CJ, Radcliffe RA, Fullerton J, Hitzemann R, Wehner JM, Flint J.

Mamm Genome. 2003 Apr;14(4):223-30.

PMID:
12682774
18.

Ethanol differentially enhances hippocampal GABA A receptor-mediated responses in protein kinase C gamma (PKC gamma) and PKC epsilon null mice.

Proctor WR, Poelchen W, Bowers BJ, Wehner JM, Messing RO, Dunwiddie TV.

J Pharmacol Exp Ther. 2003 Apr;305(1):264-70.

PMID:
12649378
19.

Inbred mouse strain differences in the establishment of long-term fear memory.

Balogh SA, Wehner JM.

Behav Brain Res. 2003 Mar 18;140(1-2):97-106.

PMID:
12644283
20.

Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference.

Hoffman PL, Miles M, Edenberg HJ, Sommer W, Tabakoff B, Wehner JM, Lewohl J.

Alcohol Clin Exp Res. 2003 Feb;27(2):155-68.

PMID:
12605065
21.

Animal models as a tool for studying mechanisms of co-abuse of alcohol and tobacco.

Balogh SA, Owens JC, Butt CM, Wehner JM, Collins AC.

Alcohol Clin Exp Res. 2002 Dec;26(12):1911-4. Review. No abstract available.

PMID:
12500117
22.

Contextual and cued fear conditioning in C57BL/6J and DBA/2J mice: context discrimination and the effects of retention interval.

Balogh SA, Radcliffe RA, Logue SF, Wehner JM.

Behav Neurosci. 2002 Dec;116(6):947-57.

PMID:
12492293
23.
24.

GABA(A)-receptor delta subunit knockout mice have multiple defects in behavioral responses to ethanol.

Mihalek RM, Bowers BJ, Wehner JM, Kralic JE, VanDoren MJ, Morrow AL, Homanics GE.

Alcohol Clin Exp Res. 2001 Dec;25(12):1708-18.

PMID:
11781502
25.

Mouse molecular genetic technologies: promise for psychiatric research.

Tecott LH, Wehner JM.

Arch Gen Psychiatry. 2001 Nov;58(11):995-1004.

PMID:
11695945
26.
27.

Quantitative genetics and mouse behavior.

Wehner JM, Radcliffe RA, Bowers BJ.

Annu Rev Neurosci. 2001;24:845-67. Review.

PMID:
11520920
28.

Differential sensitivity to the anxiolytic effects of ethanol and flunitrazepam in PKCgamma null mutant mice.

Bowers BJ, Elliott KJ, Wehner JM.

Pharmacol Biochem Behav. 2001 May-Jun;69(1-2):99-110.

PMID:
11420074
29.

Nicotine enhances latent inhibition and ameliorates ethanol-induced deficits in latent inhibition.

Gould TJ, Collins AC, Wehner JM.

Nicotine Tob Res. 2001 Feb;3(1):17-24.

PMID:
11260807
30.

Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety.

Labarca C, Schwarz J, Deshpande P, Schwarz S, Nowak MW, Fonck C, Nashmi R, Kofuji P, Dang H, Shi W, Fidan M, Khakh BS, Chen Z, Bowers BJ, Boulter J, Wehner JM, Lester HA.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2786-91. Epub 2001 Feb 20.

31.

The role of RNA editing of kainate receptors in synaptic plasticity and seizures.

Vissel B, Royle GA, Christie BR, Schiffer HH, Ghetti A, Tritto T, Perez-Otano I, Radcliffe RA, Seamans J, Sejnowski T, Wehner JM, Collins AC, O'Gorman S, Heinemann SF.

Neuron. 2001 Jan;29(1):217-27.

32.

Confirmation of contextual fear conditioning QTLs by short-term selection.

Radcliffe RA, Lowe MV, Wehner JM.

Behav Genet. 2000 May;30(3):183-91.

PMID:
11105392
33.

Mapping of quantitative trait loci for hypnotic sensitivity to ethanol in crosses derived from the C57BL/6 and DBA/2 mouse strains.

Radcliffe RA, Bohl ML, Lowe MV, Cycowski CS, Wehner JM.

Alcohol Clin Exp Res. 2000 Sep;24(9):1335-42.

PMID:
11003198
34.

Mice lacking PKC gamma exhibit decreased anxiety.

Bowers BJ, Collins AC, Tritto T, Wehner JM.

Behav Genet. 2000 Mar;30(2):111-21.

PMID:
10979601
35.

Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor.

Wick MJ, Radcliffe RA, Bowers BJ, Mascia MP, L├╝scher B, Harris RA, Wehner JM.

Eur J Neurosci. 2000 Jul;12(7):2634-8.

PMID:
10947837
36.

Alterations in hippocampal GAP-43 phosphorylation and protein level following contextual fear conditioning.

Young EA, Owen EH, Meiri KF, Wehner JM.

Brain Res. 2000 Mar 31;860(1-2):95-103.

PMID:
10727627
37.

Genetic influences on latent inhibition.

Gould TJ, Wehner JM.

Behav Neurosci. 1999 Dec;113(6):1291-6.

PMID:
10636308
38.

Background genotype modulates the effects of ╬│-PKC on the development of rapid tolerance to ethanol-induced hypothermia.

Bowers BJ, Collins AC, Wehner JM.

Addict Biol. 2000 Jan 1;5(1):47-58. doi: 10.1080/13556210071261.

PMID:
20575819
39.

High-resolution mapping of quantitative trait loci for emotionality in selected strains of mice.

Turri MG, Talbot CJ, Radcliffe RA, Wehner JM, Flint J.

Mamm Genome. 1999 Nov;10(11):1098-101. No abstract available.

PMID:
10556431
40.

Nicotine enhancement of contextual fear conditioning.

Gould TJ, Wehner JM.

Behav Brain Res. 1999 Jul;102(1-2):31-9.

PMID:
10403013
41.

Decreased ethanol sensitivity and tolerance development in gamma-protein kinase C null mutant mice is dependent on genetic background.

Bowers BJ, Owen EH, Collins AC, Abeliovich A, Tonegawa S, Wehner JM.

Alcohol Clin Exp Res. 1999 Mar;23(3):387-97.

PMID:
10195808
42.

Genetic correlation between performance on an appetitive-signaled nosepoke task and voluntary ethanol consumption.

Logue SF, Swartz RJ, Wehner JM.

Alcohol Clin Exp Res. 1998 Dec;22(9):1912-20.

PMID:
9884133
43.

Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice.

Tecott LH, Logue SF, Wehner JM, Kauer JA.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15026-31.

44.

Acute functional tolerance to ethanol and fear conditioning are genetically correlated in mice.

Radcliffe RA, Erwin VG, Wehner JM.

Alcohol Clin Exp Res. 1998 Nov;22(8):1673-9.

PMID:
9835280
45.

Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice.

Brandon EP, Logue SF, Adams MR, Qi M, Sullivan SP, Matsumoto AM, Dorsa DM, Wehner JM, McKnight GS, Idzerda RL.

J Neurosci. 1998 May 15;18(10):3639-49.

47.

Quantitative trait loci analysis affecting contextual conditioning in mice.

Caldarone B, Saavedra C, Tartaglia K, Wehner JM, Dudek BC, Flaherty L.

Nat Genet. 1997 Nov;17(3):335-7.

PMID:
9354801
48.

Quantitative trait locus analysis of contextual fear conditioning in mice.

Wehner JM, Radcliffe RA, Rosmann ST, Christensen SC, Rasmussen DL, Fulker DW, Wiles M.

Nat Genet. 1997 Nov;17(3):331-4.

PMID:
9354800

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