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Items: 1 to 50 of 182

1.

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration.

Lucic B, Chen HC, Kuzman M, Zorita E, Wegner J, Minneker V, Wang W, Fronza R, Laufs S, Schmidt M, Stadhouders R, Roukos V, Vlahovicek K, Filion GJ, Lusic M.

Nat Commun. 2019 Sep 6;10(1):4059. doi: 10.1038/s41467-019-12046-3.

2.

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis.

Herster F, Bittner Z, Codrea MC, Archer NK, Heister M, Löffler MW, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schäkel K, Grabbe S, Ghoreschi K, Miller LS, Weber ANR.

Front Immunol. 2019 Aug 16;10:1867. doi: 10.3389/fimmu.2019.01867. eCollection 2019.

3.

Humanized mice in cutaneous leishmaniasis-Suitability analysis of human PBMC transfer into immunodeficient mice.

Fischer MR, Schermann AI, Twelkmeyer T, Lorenz B, Wegner J, Jonuleit H, von Stebut E.

Exp Dermatol. 2019 Sep;28(9):1087-1090. doi: 10.1111/exd.13999. Epub 2019 Aug 1.

PMID:
31260571
4.

A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Fang H; ULTRA-DD Consortium, De Wolf H, Knezevic B, Burnham KL, Osgood J, Sanniti A, Lledó Lara A, Kasela S, De Cesco S, Wegner JK, Handunnetthi L, McCann FE, Chen L, Sekine T, Brennan PE, Marsden BD, Damerell D, O'Callaghan CA, Bountra C, Bowness P, Sundström Y, Milani L, Berg L, Göhlmann HW, Peeters PJ, Fairfax BP, Sundström M, Knight JC.

Nat Genet. 2019 Jul;51(7):1082-1091. doi: 10.1038/s41588-019-0456-1. Epub 2019 Jun 28.

PMID:
31253980
5.

Effective treatment of disseminated superficial actinic porokeratosis with chemical peels - customary treatment for a rare disease.

Lang BM, Peveling-Oberhag A, Zimmer S, Wegner J, Sohn A, Grabbe S, Staubach P.

J Dermatolog Treat. 2019 Apr 25:1-17. doi: 10.1080/09546634.2019.1610551. [Epub ahead of print]

PMID:
31018713
6.

Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes.

Burrage LC, Reynolds JJ, Baratang NV, Phillips JB, Wegner J, McFarquhar A, Higgs MR, Christiansen AE, Lanza DG, Seavitt JR, Jain M, Li X, Parry DA, Raman V, Chitayat D, Chinn IK, Bertuch AA, Karaviti L, Schlesinger AE, Earl D, Bamshad M, Savarirayan R, Doddapaneni H, Muzny D, Jhangiani SN, Eng CM, Gibbs RA, Bi W, Emrick L, Rosenfeld JA, Postlethwait J, Westerfield M, Dickinson ME, Beaudet AL, Ranza E, Huber C, Cormier-Daire V, Shen W, Mao R, Heaney JD, Orange JS; University of Washington Center for Mendelian Genomics; Undiagnosed Diseases Network, Bertola D, Yamamoto GL, Baratela WAR, Butler MG, Ali A, Adeli M, Cohn DH, Krakow D, Jackson AP, Lees M, Offiah AC, Carlston CM, Carey JC, Stewart GS, Bacino CA, Campeau PM, Lee B.

Am J Hum Genet. 2019 Mar 7;104(3):422-438. doi: 10.1016/j.ajhg.2019.01.007. Epub 2019 Feb 14.

7.

Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine.

Gherardini J, Wegner J, Chéret J, Ghatak S, Lehmann J, Alam M, Jimenez F, Funk W, Böhm M, Botchkareva NV, Ward C, Paus R, Bertolini M.

Int J Cosmet Sci. 2019 Apr;41(2):164-182. doi: 10.1111/ics.12521.

PMID:
30746733
8.

IgE-specific immunoadsorption: New treatment option for severe refractory atopic dermatitis.

Wegner J, Saloga J, Grabbe S, Wilden S, Vewinger N, Lutz J, Weinmann-Menke J, von Stebut E.

Allergy. 2019 Jun;74(6):1190-1193. doi: 10.1111/all.13716. Epub 2019 Feb 5. No abstract available.

PMID:
30636038
9.

Data, data, data….

Wegner J.

J Extra Corpor Technol. 2018 Dec;50(4):215-216. No abstract available.

10.

Semi-Rigid Nitroxide Spin Label for Long-Range EPR Distance Measurements of Lipid Bilayer Embedded β-Peptides.

Wegner J, Valora G, Halbmair K, Kehl A, Worbs B, Bennati M, Diederichsen U.

Chemistry. 2019 Feb 11;25(9):2203-2207. doi: 10.1002/chem.201805880. Epub 2019 Jan 16.

PMID:
30500095
11.

Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins.

Blanco-Sánchez B, Clément A, Fierro J Jr, Stednitz S, Phillips JB, Wegner J, Panlilio JM, Peirce JL, Washbourne P, Westerfield M.

Cell Rep. 2018 Oct 30;25(5):1281-1291.e4. doi: 10.1016/j.celrep.2018.10.005.

12.

A Recurrent De Novo Heterozygous COG4 Substitution Leads to Saul-Wilson Syndrome, Disrupted Vesicular Trafficking, and Altered Proteoglycan Glycosylation.

Ferreira CR, Xia ZJ, Clément A, Parry DA, Davids M, Taylan F, Sharma P, Turgeon CT, Blanco-Sánchez B, Ng BG, Logan CV, Wolfe LA, Solomon BD, Cho MT, Douglas G, Carvalho DR, Bratke H, Haug MG, Phillips JB, Wegner J, Tiemeyer M, Aoki K; Undiagnosed Diseases Network; Scottish Genome Partnership, Nordgren A, Hammarsjö A, Duker AL, Rohena L, Hove HB, Ek J, Adams D, Tifft CJ, Onyekweli T, Weixel T, Macnamara E, Radtke K, Powis Z, Earl D, Gabriel M, Russi AHS, Brick L, Kozenko M, Tham E, Raymond KM, Phillips JA 3rd, Tiller GE, Wilson WG, Hamid R, Malicdan MCV, Nishimura G, Grigelioniene G, Jackson A, Westerfield M, Bober MB, Gahl WA, Freeze HH.

Am J Hum Genet. 2018 Oct 4;103(4):553-567. doi: 10.1016/j.ajhg.2018.09.003.

13.

Extending the Reach with Social Media.

Wegner J.

J Extra Corpor Technol. 2018 Sep;50(3):141-142. No abstract available.

14.

Large-scale comparison of machine learning methods for drug target prediction on ChEMBL.

Mayr A, Klambauer G, Unterthiner T, Steijaert M, Wegner JK, Ceulemans H, Clevert DA, Hochreiter S.

Chem Sci. 2018 Jun 6;9(24):5441-5451. doi: 10.1039/c8sc00148k. eCollection 2018 Jun 28.

15.

Notes from the AmSECT International Meeting.

Wegner J.

J Extra Corpor Technol. 2018 Jun;50(2):75-76. No abstract available.

16.

Usherin defects lead to early-onset retinal dysfunction in zebrafish.

Dona M, Slijkerman R, Lerner K, Broekman S, Wegner J, Howat T, Peters T, Hetterschijt L, Boon N, de Vrieze E, Sorusch N, Wolfrum U, Kremer H, Neuhauss S, Zang J, Kamermans M, Westerfield M, Phillips J, van Wijk E.

Exp Eye Res. 2018 Aug;173:148-159. doi: 10.1016/j.exer.2018.05.015. Epub 2018 May 16.

17.

High-Throughput Gene Expression Profiles to Define Drug Similarity and Predict Compound Activity.

De Wolf H, Cougnaud L, Van Hoorde K, De Bondt A, Wegner JK, Ceulemans H, Göhlmann H.

Assay Drug Dev Technol. 2018 Apr;16(3):162-176. doi: 10.1089/adt.2018.845.

PMID:
29658791
18.

Quantitative analysis of zero-field splitting parameter distributions in Gd(iii) complexes.

Clayton JA, Keller K, Qi M, Wegner J, Koch V, Hintz H, Godt A, Han S, Jeschke G, Sherwin MS, Yulikov M.

Phys Chem Chem Phys. 2018 Apr 18;20(15):10470-10492. doi: 10.1039/c7cp08507a.

19.

From the Editor.

Wegner J.

J Extra Corpor Technol. 2018 Mar;50(1):3-4. No abstract available.

20.

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery.

Simm J, Klambauer G, Arany A, Steijaert M, Wegner JK, Gustin E, Chupakhin V, Chong YT, Vialard J, Buijnsters P, Velter I, Vapirev A, Singh S, Carpenter AE, Wuyts R, Hochreiter S, Moreau Y, Ceulemans H.

Cell Chem Biol. 2018 May 17;25(5):611-618.e3. doi: 10.1016/j.chembiol.2018.01.015. Epub 2018 Mar 1.

21.

From the Editor.

Wegner J.

J Extra Corpor Technol. 2017 Dec;49(4):223. No abstract available.

22.

Immunoadsorption for treatment of severe atopic dermatitis.

Wegner J, Weinmann-Menke J, von Stebut E.

Atheroscler Suppl. 2017 Nov;30:264-270. doi: 10.1016/j.atherosclerosissup.2017.05.043. Epub 2017 Jun 2. Review.

PMID:
29096848
23.

Erratum to: ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics.

Sun J, Jeliazkova N, Chupakhin V, Golib-Dzib JF, Engkvist O, Carlsson L, Wegner J, Ceulemans H, Georgiev I, Jeliazkov V, Kochev N, Ashby TJ, Chen H.

J Cheminform. 2017 Jun 14;9(1):41. doi: 10.1186/s13321-017-0222-2. No abstract available.

24.

Endothelial Glycocalyx and Cardiopulmonary Bypass.

Myers GJ, Wegner J.

J Extra Corpor Technol. 2017 Sep;49(3):174-181. Review.

25.

From the Editor.

Wegner J.

J Extra Corpor Technol. 2017 Jun;49(2):79-80. No abstract available.

26.

ExCAPE-DB: an integrated large scale dataset facilitating Big Data analysis in chemogenomics.

Sun J, Jeliazkova N, Chupakin V, Golib-Dzib JF, Engkvist O, Carlsson L, Wegner J, Ceulemans H, Georgiev I, Jeliazkov V, Kochev N, Ashby TJ, Chen H.

J Cheminform. 2017 Mar 7;9:17. doi: 10.1186/s13321-017-0203-5. eCollection 2017. Erratum in: J Cheminform. 2017 Jun 14;9(1):41.

27.

From the Editor.

Wegner J.

J Extra Corpor Technol. 2017 Mar;49(1):5-6. No abstract available.

28.

Comparing the Effects of Speech-Generating Device Display Organization on Symbol Comprehension and Use by Three Children With Developmental Delays.

Barton-Hulsey A, Wegner J, Brady NC, Bunce BH, Sevcik RA.

Am J Speech Lang Pathol. 2017 May 17;26(2):227-240. doi: 10.1044/2016_AJSLP-15-0166.

PMID:
28257530
29.

Fibrinolysis in Trauma: "Myth," "Reality," or "Something in Between".

Walsh M, Shreve J, Thomas S, Moore E, Moore H, Hake D, Pohlman T, Davis P, Ploplis V, Piscoya A, Wegner J, Bryant J, Crepinsek A, Lantry J, Sheppard F, Castellino F.

Semin Thromb Hemost. 2017 Mar;43(2):200-212. doi: 10.1055/s-0036-1597900. Epub 2017 Feb 20. Review.

PMID:
28219085
30.

Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells.

Hudecek M, Gogishvili T, Monjezi R, Wegner J, Shankar R, Kruesemann C, Miskey C, Ivics Z, Schmeer M, Schleef M.

Recent Results Cancer Res. 2016;209:37-50. doi: 10.1007/978-3-319-42934-2_3. Review.

PMID:
28101686
31.

Daily Energy Expenditure and Its Relation to Health Care Costs in Patients Undergoing Ambulatory Electrocardiographic Monitoring.

George J, Abdulla RK, Yeow R, Aggarwal A, Boura J, Wegner J, Franklin BA.

Am J Cardiol. 2017 Feb 15;119(4):658-663. doi: 10.1016/j.amjcard.2016.10.055. Epub 2016 Nov 23.

PMID:
27986262
32.

Tranexamic Acid for Trauma Resuscitation in the United States of America.

Walsh M, Thomas S, Moore E, Moore H, Piscoya A, Hake D, Son M, Pohlman T, Wegner J, Bryant J, Grassetto A, Davis P, Nielsen N, Crepinsek A, Shreve JT, Castellino F.

Semin Thromb Hemost. 2017 Mar;43(2):213-223. doi: 10.1055/s-0036-1586226. Epub 2016 Dec 1. Review.

PMID:
27907937
33.

Pulse EPR Measurements of Intramolecular Distances in a TOPP-Labeled Transmembrane Peptide in Lipids.

Halbmair K, Wegner J, Diederichsen U, Bennati M.

Biophys J. 2016 Dec 6;111(11):2345-2348. doi: 10.1016/j.bpj.2016.10.022. Epub 2016 Nov 9.

34.

Guidelines.

Wegner J.

J Extra Corpor Technol. 2016 Sep;48(3):97-98. No abstract available.

35.

EPR characterization of Mn(ii) complexes for distance determination with pulsed dipolar spectroscopy.

Keller K, Zalibera M, Qi M, Koch V, Wegner J, Hintz H, Godt A, Jeschke G, Savitsky A, Yulikov M.

Phys Chem Chem Phys. 2016 Sep 14;18(36):25120-25135.

PMID:
27711532
36.

A Look Ahead (from Behind).

Wegner J.

J Extra Corpor Technol. 2016 Jun;48(2):53-4. No abstract available.

37.

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.

Fleger-Weckmann A, Üstün Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T, Nischt R.

Matrix Biol. 2016 Dec;56:42-56. doi: 10.1016/j.matbio.2016.05.002. Epub 2016 May 25.

PMID:
27234308
38.

Laminin α5 in the keratinocyte basement membrane is required for epidermal-dermal intercommunication.

Wegner J, Loser K, Apsite G, Nischt R, Eckes B, Krieg T, Werner S, Sorokin L.

Matrix Biol. 2016 Dec;56:24-41. doi: 10.1016/j.matbio.2016.05.001. Epub 2016 May 24.

PMID:
27234307
39.

[Cystitis. Ultrasound only in complicated anamnesis].

Wegner J.

MMW Fortschr Med. 2015 Oct 22;157(18):17. German. No abstract available.

PMID:
26985484
40.

Six-Year Clinical Outcomes After Catheter Ablation of Atrial Fibrillation in Patients With Impaired Left Ventricular Function.

Rillig A, Makimoto H, Wegner J, Lin T, Heeger C, Lemes C, Fink T, Metzner A, Wissner E, Mathew S, Wohlmuth P, Kuck KH, Tilz RR, Ouyang F.

J Cardiovasc Electrophysiol. 2015 Nov;26(11):1169-1179. doi: 10.1111/jce.12765. Epub 2015 Sep 3.

PMID:
26217925
41.

Experience matters: long-term results of pulmonary vein isolation using a robotic navigation system for the treatment of paroxysmal atrial fibrillation.

Rillig A, Lin T, Schmidt B, Feige B, Heeger C, Wegner J, Wissner E, Metzner A, Arya A, Mathew S, Wohlmuth P, Ouyang F, Kuck KH, Tilz RR.

Clin Res Cardiol. 2016 Feb;105(2):106-16. doi: 10.1007/s00392-015-0892-6. Epub 2015 Jul 22.

PMID:
26199066
42.

High-density preculture of PBMCs restores defective sensitivity of circulating CD8 T cells to virus- and tumor-derived antigens.

Wegner J, Hackenberg S, Scholz CJ, Chuvpilo S, Tyrsin D, Matskevich AA, Grigoleit GU, Stevanović S, Hünig T.

Blood. 2015 Jul 9;126(2):185-94. doi: 10.1182/blood-2015-01-622704. Epub 2015 May 29.

PMID:
26024876
43.

Disubstituted Bis-THF Moieties as New P2 Ligands in Nonpeptidal HIV-1 Protease Inhibitors (II).

Hohlfeld K, Wegner JK, Kesteleyn B, Linclau B, Unge J.

J Med Chem. 2015 May 14;58(9):4029-38. doi: 10.1021/acs.jmedchem.5b00358. Epub 2015 Apr 30.

PMID:
25897791
44.

iPads, mobile technologies, and communication applications: a survey of family wants, needs, and preferences.

Meder AM, Wegner JR.

Augment Altern Commun. 2015 Mar;31(1):27-36. doi: 10.3109/07434618.2014.995223.

PMID:
25685882
45.

Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease.

Karbach S, Croxford AL, Oelze M, Schüler R, Minwegen D, Wegner J, Koukes L, Yogev N, Nikolaev A, Reißig S, Ullmann A, Knorr M, Waldner M, Neurath MF, Li H, Wu Z, Brochhausen C, Scheller J, Rose-John S, Piotrowski C, Bechmann I, Radsak M, Wild P, Daiber A, von Stebut E, Wenzel P, Waisman A, Münzel T.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2658-68. doi: 10.1161/ATVBAHA.114.304108. Epub 2014 Oct 23.

PMID:
25341795
46.

Mutation of POC1B in a severe syndromic retinal ciliopathy.

Beck BB, Phillips JB, Bartram MP, Wegner J, Thoenes M, Pannes A, Sampson J, Heller R, Göbel H, Koerber F, Neugebauer A, Hedergott A, Nürnberg G, Nürnberg P, Thiele H, Altmüller J, Toliat MR, Staubach S, Boycott KM, Valente EM, Janecke AR, Eisenberger T, Bergmann C, Tebbe L, Wang Y, Wu Y, Fry AM, Westerfield M, Wolfrum U, Bolz HJ.

Hum Mutat. 2014 Oct;35(10):1153-62. doi: 10.1002/humu.22618. Epub 2014 Aug 11.

47.

Benchmarking of protein descriptor sets in proteochemometric modeling (part 2): modeling performance of 13 amino acid descriptor sets.

van Westen GJ, Swier RF, Cortes-Ciriano I, Wegner JK, Overington JP, Ijzerman AP, van Vlijmen HW, Bender A.

J Cheminform. 2013 Sep 24;5(1):42. doi: 10.1186/1758-2946-5-42.

48.

Benchmarking of protein descriptor sets in proteochemometric modeling (part 1): comparative study of 13 amino acid descriptor sets.

van Westen GJ, Swier RF, Wegner JK, Ijzerman AP, van Vlijmen HW, Bender A.

J Cheminform. 2013 Sep 23;5(1):41. doi: 10.1186/1758-2946-5-41.

49.

The cone-dominant retina and the inner ear of zebrafish express the ortholog of CLRN1, the causative gene of human Usher syndrome type 3A.

Phillips JB, Västinsalo H, Wegner J, Clément A, Sankila EM, Westerfield M.

Gene Expr Patterns. 2013 Dec;13(8):473-81. doi: 10.1016/j.gep.2013.09.001. Epub 2013 Sep 14.

50.

Resolving social problems associated with sexuality: can a "sex-positive" approach help?

Williams DJ, Prior E, Wegner J.

Soc Work. 2013 Jul;58(3):273-6. No abstract available.

PMID:
24032308

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