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Items: 7


Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates.

Weiß F, Hammer HS, Klein K, Planatscher H, Zanger UM, Norén A, Wegler C, Artursson P, Joos TO, Poetz O.

Drug Metab Dispos. 2018 Apr;46(4):387-396. doi: 10.1124/dmd.117.078626. Epub 2018 Jan 17.


Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes.

Wegler C, Gaugaz FZ, Andersson TB, Wiśniewski JR, Busch D, Gröer C, Oswald S, Norén A, Weiss F, Hammer HS, Joos TO, Poetz O, Achour B, Rostami-Hodjegan A, van de Steeg E, Wortelboer HM, Artursson P.

Mol Pharm. 2017 Sep 5;14(9):3142-3151. doi: 10.1021/acs.molpharmaceut.7b00364. Epub 2017 Aug 16.


A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

Karlgren M, Simoff I, Backlund M, Wegler C, Keiser M, Handin N, Müller J, Lundquist P, Jareborg AC, Oswald S, Artursson P.

J Pharm Sci. 2017 Sep;106(9):2909-2913. doi: 10.1016/j.xphs.2017.04.018. Epub 2017 Apr 24.


Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

Mateus A, Treyer A, Wegler C, Karlgren M, Matsson P, Artursson P.

Sci Rep. 2017 Feb 22;7:43047. doi: 10.1038/srep43047.


Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions.

Wiśniewski JR, Wegler C, Artursson P.

Anal Biochem. 2016 Sep 15;509:82-88. doi: 10.1016/j.ab.2016.06.006. Epub 2016 Jun 14.


Effects of Osteoporosis-Inducing Drugs on Vitamin D-Related Gene Transcription and Mineralization in MG-63 and Saos-2 Cells.

Wegler C, Wikvall K, Norlin M.

Basic Clin Pharmacol Toxicol. 2016 Nov;119(5):436-442. doi: 10.1111/bcpt.12612. Epub 2016 May 20.

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