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Recommendations for improving clinical trial design to facilitate the study of youth-onset type 2 diabetes.

Jalaludin MY, Barrientos-Pérez M, Hafez M, Lynch J, Shehadeh N, Turan S, Weghuber D.

Clin Trials. 2019 Aug 26:1740774519870190. doi: 10.1177/1740774519870190. [Epub ahead of print]


Could sport be part of pediatric obesity prevention and treatment? Expert conclusions from the 28th European Childhood Obesity Group Congress.

Ring-Dimitriou S, Krustrup P, Coelho-E-Silva MJ, Mota J, Seabra A, Rego C, Mazur A, Vlachopapadopoulou E, Caroli M, Frelut ML, Erhardt E, Forslund A, Boyland E, Weghuber D, Thivel D.

J Sport Health Sci. 2019 Jul;8(4):350-352. doi: 10.1016/j.jshs.2019.01.007. Epub 2019 Jan 18.


Brown adipose tissue estimated with the magnetic resonance imaging fat fraction is associated with glucose metabolism in adolescents.

Lundström E, Ljungberg J, Andersson J, Manell H, Strand R, Forslund A, Bergsten P, Weghuber D, Mörwald K, Zsoldos F, Widhalm K, Meissnitzer M, Ahlström H, Kullberg J.

Pediatr Obes. 2019 Sep;14(9):e12531. doi: 10.1111/ijpo.12531. Epub 2019 Jul 9.


Guava (Psidium guajava) Fruit Extract Prepared by Supercritical CO2 Extraction Inhibits Intestinal Glucose Resorption in a Double-Blind, Randomized Clinical Study.

König A, Schwarzinger B, Stadlbauer V, Lanzerstorfer P, Iken M, Schwarzinger C, Kolb P, Schwarzinger S, Mörwald K, Brunner S, Höglinger O, Weghuber D, Weghuber J.

Nutrients. 2019 Jul 3;11(7). pii: E1512. doi: 10.3390/nu11071512.


Hyperglucagonemia in youth is associated with high plasma free fatty acids, visceral adiposity, and impaired glucose tolerance.

Manell H, Kristinsson H, Kullberg J, Ubhayasekera SJK, Mörwald K, Staaf J, Cadamuro J, Zsoldos F, Göpel S, Sargsyan E, Ahlström H, Bergquist J, Weghuber D, Forslund A, Bergsten P.

Pediatr Diabetes. 2019 Jul 4. doi: 10.1111/pedi.12890. [Epub ahead of print]


Youth-Onset Type 2 Diabetes Manifestations in other Specialties: Its Many Disguises.

Weghuber D, Barrientos-Pérez M, Kovarenko M.

Ann Nutr Metab. 2019;74(4):339-347. doi: 10.1159/000500234. Epub 2019 May 16. Review.


Liraglutide in Children and Adolescents with Type 2 Diabetes.

Tamborlane WV, Barrientos-Pérez M, Fainberg U, Frimer-Larsen H, Hafez M, Hale PM, Jalaludin MY, Kovarenko M, Libman I, Lynch JL, Rao P, Shehadeh N, Turan S, Weghuber D, Barrett T; Ellipse Trial Investigators.

N Engl J Med. 2019 Aug 15;381(7):637-646. doi: 10.1056/NEJMoa1903822. Epub 2019 Apr 28.


Consumption of Sugar-Sweetened Beverages in Paediatric Age: A Position Paper of the European Academy of Paediatrics and the European Childhood Obesity Group.

Dereń K, Weghuber D, Caroli M, Koletzko B, Thivel D, Frelut ML, Socha P, Grossman Z, Hadjipanayis A, Wyszyńska J, Mazur A.

Ann Nutr Metab. 2019;74(4):296-302. doi: 10.1159/000499828. Epub 2019 Apr 23.


Childhood Obesity: The Need to Translate Research into Daily Practice: Announcing the Annals of Nutrition and Metabolism as the Official Journal of the European Childhood Obesity Group.

Weghuber D, Boyland E, Caroli M, Erhardt E, Frelut ML, Forslund A, Mazur A, Ring-Dimitriou S, Vlachopapadopoulou ΕA, Thivel D.

Ann Nutr Metab. 2019;74(1):80-82. doi: 10.1159/000495905. Epub 2019 Jan 7. No abstract available.


Evaluation of reference intervals of haematological and biochemical markers in an Austrian adolescent study cohort.

Bogner B, Schwenoha K, Vogl M, Weghuber D, Roth C, Kipman U, Cadamuro J, Oostingh GJ.

Clin Chem Lab Med. 2019 May 27;57(6):891-900. doi: 10.1515/cclm-2018-0715.


Fully convolutional networks for automated segmentation of abdominal adipose tissue depots in multicenter water-fat MRI.

Langner T, Hedström A, Mörwald K, Weghuber D, Forslund A, Bergsten P, Ahlström H, Kullberg J.

Magn Reson Med. 2019 Apr;81(4):2736-2745. doi: 10.1002/mrm.27550. Epub 2018 Oct 12.


Clinical and metabolic characterization of obese subjects without non-alcoholic fatty liver: A targeted metabolomics approach.

Feldman A, Eder SK, Felder TK, Paulweber B, Zandanell S, Stechemesser L, Schranz M, Strebinger G, Huber-Schönauer U, Niederseer D, Patsch W, Weghuber D, Tevini J, Datz C, Aigner E.

Diabetes Metab. 2019 Apr;45(2):132-139. doi: 10.1016/j.diabet.2018.09.003. Epub 2018 Sep 26.


Vedolizumab use after failure of TNF-α antagonists in children and adolescents with inflammatory bowel disease.

Schneider AM, Weghuber D, Hetzer B, Entenmann A, Müller T, Zimmermann G, Schütz S, Huber WD, Pichler J.

BMC Gastroenterol. 2018 Sep 15;18(1):140. doi: 10.1186/s12876-018-0868-x.


SALTO - Study Protocol and Rationale of a Community-Oriented Obesity Prevention Program in the Kindergarten.

Ring-Dimitriou S, Freudenthaler T, Aistleitner V, Horvath G, Stallinger J, Dimitriou M, Ardelt-Gattinger E, Weghuber D.

Obes Facts. 2018;11(3):234-246. doi: 10.1159/000481139. Epub 2018 Jun 30.


High DPP-4 Concentrations in Adolescents Are Associated With Low Intact GLP-1.

Stenlid R, Manell H, Halldin M, Kullberg J, Ahlström H, Manukyan L, Weghuber D, Paulmichl K, Zsoldos F, Bergsten P, Forslund A.

J Clin Endocrinol Metab. 2018 Aug 1;103(8):2958-2966. doi: 10.1210/jc.2018-00194.


Reviewing and addressing the link between mass media and the increase in obesity among European children: The European Academy of Paediatrics (EAP) and The European Childhood Obesity Group (ECOG) consensus statement.

Mazur A, Caroli M, Radziewicz-Winnicki I, Nowicka P, Weghuber D, Neubauer D, Dembiński Ł, Crawley FP, White M, Hadjipanayis A.

Acta Paediatr. 2018 Apr;107(4):568-576. doi: 10.1111/apa.14136. Epub 2017 Nov 22.


Adiponectin Predicts High-Density Lipoprotein Cholesterol Efflux Capacity in Adults Irrespective of Body Mass Index and Fat Distribution.

Marsche G, Zelzer S, Meinitzer A, Kern S, Meissl S, Pregartner G, Weghuber D, Almer G, Mangge H.

J Clin Endocrinol Metab. 2017 Nov 1;102(11):4117-4123. doi: 10.1210/jc.2017-00933.


Physical Activity and Physical Fitness in Pediatric Obesity: What are the First Steps for Clinicians? Expert Conclusion from the 2016 ECOG Workshop.

O'Malley G, Ring-Dimitriou S, Nowicka P, Vania A, Frelut ML, Farpour-Lambert N, Weghuber D, Thivel D.

Int J Exerc Sci. 2017 Jul 1;10(4):487-496. eCollection 2017.


Automated segmentation of human cervical-supraclavicular adipose tissue in magnetic resonance images.

Lundström E, Strand R, Forslund A, Bergsten P, Weghuber D, Ahlström H, Kullberg J.

Sci Rep. 2017 Jun 8;7(1):3064. doi: 10.1038/s41598-017-01586-7.


Metabolomic profiling identifies potential pathways involved in the interaction of iron homeostasis with glucose metabolism.

Stechemesser L, Eder SK, Wagner A, Patsch W, Feldman A, Strasser M, Auer S, Niederseer D, Huber-Schönauer U, Paulweber B, Zandanell S, Ruhaltinger S, Weghuber D, Haschke-Becher E, Grabmer C, Rohde E, Datz C, Felder TK, Aigner E.

Mol Metab. 2016 Oct 31;6(1):38-47. doi: 10.1016/j.molmet.2016.10.006. eCollection 2017 Jan.


Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity.

Staaf J, Labmayr V, Paulmichl K, Manell H, Cen J, Ciba I, Dahlbom M, Roomp K, Anderwald CH, Meissnitzer M, Schneider R, Forslund A, Widhalm K, Bergquist J, Ahlström H, Bergsten P, Weghuber D, Kullberg J.

Pancreas. 2017 Mar;46(3):358-365. doi: 10.1097/MPA.0000000000000771.


Crave, Like, Eat: Determinants of Food Intake in a Sample of Children and Adolescents with a Wide Range in Body Mass.

Hofmann J, Meule A, Reichenberger J, Weghuber D, Ardelt-Gattinger E, Blechert J.

Front Psychol. 2016 Sep 21;7:1389. eCollection 2016.


Modification and Validation of the Triglyceride-to-HDL Cholesterol Ratio as a Surrogate of Insulin Sensitivity in White Juveniles and Adults without Diabetes Mellitus: The Single Point Insulin Sensitivity Estimator (SPISE).

Paulmichl K, Hatunic M, Højlund K, Jotic A, Krebs M, Mitrakou A, Porcellati F, Tura A, Bergsten P, Forslund A, Manell H, Widhalm K, Weghuber D, Anderwald CH; Beta-JUDO Investigators; RISC Investigators.

Clin Chem. 2016 Sep;62(9):1211-9. doi: 10.1373/clinchem.2016.257436. Epub 2016 Jul 28.


Impulsivity, perceived self-regulatory success in dieting, and body mass in children and adolescents: A moderated mediation model.

Meule A, Hofmann J, Weghuber D, Blechert J.

Appetite. 2016 Dec 1;107:15-20. doi: 10.1016/j.appet.2016.07.022. Epub 2016 Jul 17.


Branched-chain amino acids are associated with cardiometabolic risk profiles found already in lean, overweight and obese young.

Mangge H, Zelzer S, Prüller F, Schnedl WJ, Weghuber D, Enko D, Bergsten P, Haybaeck J, Meinitzer A.

J Nutr Biochem. 2016 Jun;32:123-7. doi: 10.1016/j.jnutbio.2016.02.007. Epub 2016 Mar 21.


Muscle Strength and Fitness in Pediatric Obesity: a Systematic Review from the European Childhood Obesity Group.

Thivel D, Ring-Dimitriou S, Weghuber D, Frelut ML, O'Malley G.

Obes Facts. 2016;9(1):52-63. doi: 10.1159/000443687. Epub 2016 Feb 23. Review.


[Gender differences of psychological, nutritional, and physical fitness variables influencing obesity/overweight in Austrian children and adolescents].

Ardelt-Gattinger E, Ring-Dimitriou S, Hofmann J, Paulmichl K, Zsoldos F, Weghuber D.

Wien Med Wochenschr. 2016 Mar;166(3-4):111-6. doi: 10.1007/s10354-015-0427-9. Epub 2016 Feb 5. German.


Dietary restraint and impulsivity modulate neural responses to food in adolescents with obesity and healthy adolescents.

Hofmann J, Ardelt-Gattinger E, Paulmichl K, Weghuber D, Blechert J.

Obesity (Silver Spring). 2015 Nov;23(11):2183-9. doi: 10.1002/oby.21254. Epub 2015 Sep 18.


Mitochondrial Haplogroup T Is Associated with Obesity in Austrian Juveniles and Adults.

Ebner S, Mangge H, Langhof H, Halle M, Siegrist M, Aigner E, Paulmichl K, Paulweber B, Datz C, Sperl W, Kofler B, Weghuber D.

PLoS One. 2015 Aug 31;10(8):e0135622. doi: 10.1371/journal.pone.0135622. eCollection 2015.


The Potential Role of Iron and Copper in Pediatric Obesity and Nonalcoholic Fatty Liver Disease.

Feldman A, Aigner E, Weghuber D, Paulmichl K.

Biomed Res Int. 2015;2015:287401. doi: 10.1155/2015/287401. Epub 2015 Jul 26. Review.


Natural course of subjects with elevated liver tests and normal liver histology.

Strasser M, Stadlmayr A, Haufe H, Stickel F, Ferenci P, Patsch W, Feldman A, Weghuber D, Datz C, Aigner E.

Liver Int. 2016 Jan;36(1):119-25. doi: 10.1111/liv.12935. Epub 2015 Sep 6.


In psychiatrically healthy individuals, overweight women but not men have lower tryptophan levels.

Raheja UK, Fuchs D, Giegling I, Brenner LA, Rovner SF, Mohyuddin I, Weghuber D, Mangge H, Rujescu D, Postolache TT.

Pteridines. 2015 Jun;26(2):79-84.


Oxidized LDL Is Strictly Limited to Hyperthyroidism Irrespective of Fat Feeding in Female Sprague Dawley Rats.

Zelzer S, Mangge H, Pailer S, Ainoedhofer H, Kieslinger P, Stojakovic T, Scharnagl H, Prüller F, Weghuber D, Datz C, Haybaeck J, Obermayer-Pietsch B, Trummer C, Gostner J, Gruber HJ.

Int J Mol Sci. 2015 May 21;16(5):11689-98. doi: 10.3390/ijms160511689.


Patatin-like phospholipase 3 (rs738409) gene polymorphism is associated with increased liver enzymes in obese adolescents and metabolic syndrome in all ages.

Mangge H, Baumgartner BG, Zelzer S, Prüller F, Schnedl WJ, Reininghaus EZ, Haybaeck J, Lackner C, Stauber R, Aigner E, Weghuber D.

Aliment Pharmacol Ther. 2015 Jul;42(1):99-105. doi: 10.1111/apt.13232. Epub 2015 May 5.


Differences in pharmacokinetics of apple polyphenols after standardized oral consumption of unprocessed apple juice.

Wruss J, Lanzerstorfer P, Huemer S, Himmelsbach M, Mangge H, Höglinger O, Weghuber D, Weghuber J.

Nutr J. 2015 Apr 1;14:32. doi: 10.1186/s12937-015-0018-z.


25OH-Vitamin D3 Levels in Obesity and Metabolic Syndrome-Unaltered in Young and not Correlated to Carotid IMT in All Ages.

Mangge H, Zelzer S, Meinitzer A, Stelzer I, Schnedl WJ, Weghuber D, Fuchs D, Postolache TT, Aigner E, Datz C, Reininghaus EZ.

Curr Pharm Des. 2015;21(17):2243-9.


Impact of age and metabolic syndrome on the adipokine profile in childhood and adult obesity.

Weghuber D, Mangge H, Hochbrugger E, Stulnig TM.

Exp Clin Endocrinol Diabetes. 2014 Jun;122(6):363-7. doi: 10.1055/s-0034-1375647. Epub 2014 Jun 18.


The assessment of eating behaviour in children who are obese: a psychological approach. A position paper from the European childhood obesity group.

Braet C, O'Malley G, Weghuber D, Vania A, Erhardt E, Nowicka P, Mazur A, Frelut ML, Ardelt-Gattinger E.

Obes Facts. 2014;7(3):153-64. doi: 10.1159/000362391. Epub 2014 May 10. Review.


Disturbed tryptophan metabolism in cardiovascular disease.

Mangge H, Stelzer I, Reininghaus EZ, Weghuber D, Postolache TT, Fuchs D.

Curr Med Chem. 2014 Jun;21(17):1931-7. Review.


Normal weight estonian prepubertal boys show a more cardiovascular-risk-associated adipose tissue distribution than austrian counterparts.

Wallner-Liebmann SJ, Moeller R, Horejsi R, Jürimäe T, Jürimäe J, Mäestu J, Purge P, Saar M, Tafeit E, Kaimbacher P, Kruschitz R, Weghuber D, Schnedl WJ, Mangge H.

ISRN Obes. 2013 Jan 14;2013:506751. doi: 10.1155/2013/506751. eCollection 2013.


The burden of pneumococcal meningitis in Austrian children between 2001 and 2008.

Klobassa DS, Zoehrer B, Paulke-Korinek M, Gruber-Sedlmayr U, Pfurtscheller K, Strenger V, Sonnleitner A, Kerbl R, Ausserer B, Arocker W, Kaulfersch W, Hausberger B, Covi B, Eitelberger F, Vécsei A, Simma B, Birnbacher R, Kurz H, Zwiauer K, Weghuber D, Heuberger S, Quehenberger F, Kollaritsch H, Zenz W.

Eur J Pediatr. 2014 Jul;173(7):871-8. doi: 10.1007/s00431-013-2260-8. Epub 2014 Jan 14.


A Positive Association between T. gondii Seropositivity and Obesity.

Reeves GM, Mazaheri S, Snitker S, Langenberg P, Giegling I, Hartmann AM, Konte B, Friedl M, Okusaga O, Groer MW, Mangge H, Weghuber D, Allison DB, Rujescu D, Postolache TT.

Front Public Health. 2013 Dec 25;1:73. doi: 10.3389/fpubh.2013.00073. eCollection 2013.


Timely diagnosis of malalignment of the distal extremities is crucial in morbidly obese juveniles.

Landauer F, Huber G, Paulmichl K, O'Malley G, Mangge H, Weghuber D.

Obes Facts. 2013;6(6):542-51. doi: 10.1159/000357280. Epub 2013 Dec 6.


The Role of Vitamin D in Atherosclerosis Inflammation Revisited: More a Bystander than a Player?

Mangge H, Weghuber D, Prassl R, Haara A, Schnedl W, Postolache TT, Fuchs D.

Curr Vasc Pharmacol. 2015;13(3):392-8. Review.


Obesity-related dysregulation of the tryptophan-kynurenine metabolism: role of age and parameters of the metabolic syndrome.

Mangge H, Summers KL, Meinitzer A, Zelzer S, Almer G, Prassl R, Schnedl WJ, Reininghaus E, Paulmichl K, Weghuber D, Fuchs D.

Obesity (Silver Spring). 2014 Jan;22(1):195-201. doi: 10.1002/oby.20491. Epub 2013 Jul 5.


Antioxidant food supplements and obesity-related inflammation.

Mangge H, Summers K, Almer G, Prassl R, Weghuber D, Schnedl W, Fuchs D.

Curr Med Chem. 2013;20(18):2330-7. Review.


High risk vs. "metabolically healthy" phenotype in juvenile obesity - neck subcutaneous adipose tissue and serum uric acid are clinically relevant.

Weghuber D, Zelzer S, Stelzer I, Paulmichl K, Kammerhofer D, Schnedl W, Molnar D, Mangge H.

Exp Clin Endocrinol Diabetes. 2013 Jul;121(7):384-90. doi: 10.1055/s-0033-1341440. Epub 2013 Mar 21.


Uric acid best predicts metabolically unhealthy obesity with increased cardiovascular risk in youth and adults.

Mangge H, Zelzer S, Puerstner P, Schnedl WJ, Reeves G, Postolache TT, Weghuber D.

Obesity (Silver Spring). 2013 Jan;21(1):E71-7. doi: 10.1002/oby.20061. Epub 2013 Jan 29.


Association of symptoms of attention-deficit/hyperactivity disorder with physical activity, media time, and food intake in children and adolescents.

van Egmond-Fröhlich AW, Weghuber D, de Zwaan M.

PLoS One. 2012;7(11):e49781. doi: 10.1371/journal.pone.0049781. Epub 2012 Nov 14.


Link between leptin and interleukin-6 levels in the initial phase of obesity related inflammation.

Stelzer I, Zelzer S, Raggam RB, Prüller F, Truschnig-Wilders M, Meinitzer A, Schnedl WJ, Horejsi R, Möller R, Weghuber D, Reeves G, Postolache TT, Mangge H.

Transl Res. 2012 Feb;159(2):118-24. doi: 10.1016/j.trsl.2011.10.001. Epub 2011 Nov 4.


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