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Items: 1 to 50 of 59

1.

Murine cardiac growth, TRPC channels, and cGMP kinase I.

Domes K, Patrucco E, Loga F, Dietrich A, Birnbaumer L, Wegener JW, Hofmann F.

Pflugers Arch. 2015 Oct;467(10):2229-34. doi: 10.1007/s00424-014-1682-0. Epub 2014 Dec 30.

PMID:
25547873
2.

Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity.

Dongmo AB, Nkeng-Efouet PA, Devkota KP, Wegener JW, Sewald N, Wagner H, Vierling W.

Phytomedicine. 2014 May 15;21(6):787-92. doi: 10.1016/j.phymed.2014.02.009. Epub 2014 Mar 25.

PMID:
24680617
3.

L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.

Hofmann F, Flockerzi V, Kahl S, Wegener JW.

Physiol Rev. 2014 Jan;94(1):303-26. doi: 10.1152/physrev.00016.2013. Review.

4.

Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.

Wegener JW, Loga F, Stegner D, Nieswandt B, Hofmann F.

FASEB J. 2014 Mar;28(3):1044-8. doi: 10.1096/fj.13-237925. Epub 2013 Nov 19.

PMID:
24253251
5.

The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone.

Loga F, Domes K, Freichel M, Flockerzi V, Dietrich A, Birnbaumer L, Hofmann F, Wegener JW.

Cardiovasc Res. 2013 Nov 1;100(2):280-7. doi: 10.1093/cvr/cvt176. Epub 2013 Jul 4.

6.

cGMP-dependent protein kinases (cGK).

Hofmann F, Wegener JW.

Methods Mol Biol. 2013;1020:17-50. doi: 10.1007/978-1-62703-459-3_2. Review.

PMID:
23709024
7.

Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.

Ding J, Domes K, Hofmann F, Wegener JW.

Pflugers Arch. 2013 Jul;465(7):955-64. doi: 10.1007/s00424-012-1212-x. Epub 2013 Jan 22.

PMID:
23338940
8.

Furan in heat-treated foods: formation, exposure, toxicity, and aspects of risk assessment.

Moro S, Chipman JK, Wegener JW, Hamberger C, Dekant W, Mally A.

Mol Nutr Food Res. 2012 Aug;56(8):1197-211. doi: 10.1002/mnfr.201200093. Epub 2012 May 29. Review.

PMID:
22641279
9.

Deletion of the C-terminal phosphorylation sites in the cardiac β-subunit does not affect the basic β-adrenergic response of the heart and the Ca(v)1.2 channel.

Brandmayr J, Poomvanicha M, Domes K, Ding J, Blaich A, Wegener JW, Moosmang S, Hofmann F.

J Biol Chem. 2012 Jun 29;287(27):22584-92. doi: 10.1074/jbc.M112.366484. Epub 2012 May 15.

10.

Mutation of the calmodulin binding motif IQ of the L-type Ca(v)1.2 Ca2+ channel to EQ induces dilated cardiomyopathy and death.

Blaich A, Pahlavan S, Tian Q, Oberhofer M, Poomvanicha M, Lenhardt P, Domes K, Wegener JW, Moosmang S, Ruppenthal S, Scholz A, Lipp P, Hofmann F.

J Biol Chem. 2012 Jun 29;287(27):22616-25. doi: 10.1074/jbc.M112.357921. Epub 2012 May 15.

11.

Neuronal cGMP kinase I is essential for stimulation of duodenal bicarbonate secretion by luminal acid.

Singh AK, Spiessberger B, Zheng W, Xiao F, Lukowski R, Wegener JW, Weinmeister P, Saur D, Klein S, Schemann M, Krueger D, Seidler U, Hofmann F.

FASEB J. 2012 Apr;26(4):1745-54. doi: 10.1096/fj.11-200394. Epub 2012 Jan 17.

PMID:
22253479
12.

Kinetics of relaxation by cGMP/cGKI signaling in fundus smooth muscle.

Ertl C, Lukowski R, Sigl K, Schlossmann J, Hofmann F, Wegener JW.

Eur J Pharmacol. 2011 Nov 16;670(1):266-71. doi: 10.1016/j.ejphar.2011.07.048. Epub 2011 Aug 19.

PMID:
21914444
13.

Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.

Domes K, Ding J, Lemke T, Blaich A, Wegener JW, Brandmayr J, Moosmang S, Hofmann F.

J Biol Chem. 2011 Sep 30;286(39):33863-71. doi: 10.1074/jbc.M111.252312. Epub 2011 Aug 5.

14.

Effect-directed analysis of municipal landfill soil reveals novel developmental toxicants in the zebrafish Danio rerio.

Legler J, van Velzen M, Cenijn PH, Houtman CJ, Lamoree MH, Wegener JW.

Environ Sci Technol. 2011 Oct 1;45(19):8552-8. doi: 10.1021/es201099s. Epub 2011 Sep 12.

PMID:
21823594
15.

Facilitation and Ca2+-dependent inactivation are modified by mutation of the Ca(v)1.2 channel IQ motif.

Poomvanicha M, Wegener JW, Blaich A, Fischer S, Domes K, Moosmang S, Hofmann F.

J Biol Chem. 2011 Jul 29;286(30):26702-7. doi: 10.1074/jbc.M111.247841. Epub 2011 Jun 10.

16.

Furan levels in fruit and vegetables juices, nutrition drinks and bakery products.

Wegener JW, López-Sánchez P.

Anal Chim Acta. 2010 Jul 5;672(1-2):55-60. doi: 10.1016/j.aca.2010.04.042. Epub 2010 May 17.

PMID:
20579490
17.

Facilitation of murine cardiac L-type Ca(v)1.2 channel is modulated by calmodulin kinase II-dependent phosphorylation of S1512 and S1570.

Blaich A, Welling A, Fischer S, Wegener JW, Köstner K, Hofmann F, Moosmang S.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10285-9. doi: 10.1073/pnas.0914287107. Epub 2010 May 17.

18.

A complex of Ca(V)1.2/PKC is involved in muscarinic signaling in smooth muscle.

Huster M, Frei E, Hofmann F, Wegener JW.

FASEB J. 2010 Aug;24(8):2651-9. doi: 10.1096/fj.09-149856. Epub 2010 Apr 6.

PMID:
20371628
19.

IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.

Desch M, Sigl K, Hieke B, Salb K, Kees F, Bernhard D, Jochim A, Spiessberger B, Höcherl K, Feil R, Feil S, Lukowski R, Wegener JW, Hofmann F, Schlossmann J.

Cardiovasc Res. 2010 Jun 1;86(3):496-505. doi: 10.1093/cvr/cvq008. Epub 2010 Jan 15.

PMID:
20080989
20.

Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.

Frei E, Huster M, Smital P, Schlossmann J, Hofmann F, Wegener JW.

Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G834-9. doi: 10.1152/ajpgi.00095.2009. Epub 2009 Jul 23.

21.

Phospholipase C mediated Ca2+ signals in murine urinary bladder smooth muscle.

Frei E, Hofmann F, Wegener JW.

Eur J Pharmacol. 2009 May 21;610(1-3):106-9. doi: 10.1016/j.ejphar.2009.03.036. Epub 2009 Mar 19.

PMID:
19303404
22.

United Nations Environment Programme Capacity Building Pilot Project--training and interlaboratory study on persistent organic pollutant analysis under the Stockholm Convention.

de Boer J, Leslie H, van Leeuwen SP, Wegener JW, van Bavel B, Lindström G, Lahoutifard N, Fiedler H.

Anal Chim Acta. 2008 Jun 9;617(1-2):208-15. doi: 10.1016/j.aca.2008.01.081. Epub 2008 Feb 9.

PMID:
18486660
23.

Severe intestinal obstruction on induced smooth muscle-specific ablation of the transcription factor SRF in adult mice.

Angstenberger M, Wegener JW, Pichler BJ, Judenhofer MS, Feil S, Alberti S, Feil R, Nordheim A.

Gastroenterology. 2007 Dec;133(6):1948-59. Epub 2007 Sep 5.

PMID:
18054566
24.

Rescue of cGMP kinase I knockout mice by smooth muscle specific expression of either isozyme.

Weber S, Bernhard D, Lukowski R, Weinmeister P, Wörner R, Wegener JW, Valtcheva N, Feil S, Schlossmann J, Hofmann F, Feil R.

Circ Res. 2007 Nov 26;101(11):1096-103. Epub 2007 Sep 27.

PMID:
17901360
25.

Distribution of organotin compounds in the bivalves of the Aegean Sea, Greece.

Chandrinou S, Stasinakis AS, Thomaidis NS, Nikolaou A, Wegener JW.

Environ Int. 2007 Feb;33(2):226-32. Epub 2006 Oct 24.

PMID:
17067676
26.

Improved glucuronide hydrolysis in the determination of urinary 1-hydroxypyrene.

Wegener JW, Hopman-Ubbels GH, Van Velzen M.

J Chromatogr A. 2006 Nov 17;1134(1-2):232-5. Epub 2006 Sep 26.

PMID:
16999971
27.

cGMP signals mainly through cAMP kinase in permeabilized murine aorta.

Wörner R, Lukowski R, Hofmann F, Wegener JW.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H237-44. Epub 2006 Aug 18.

28.

Control of intestinal motility by the Ca(v)1.2 L-type calcium channel in mice.

Wegener JW, Schulla V, Koller A, Klugbauer N, Feil R, Hofmann F.

FASEB J. 2006 Jun;20(8):1260-2. Epub 2006 Apr 24.

PMID:
16636102
29.

Mouse models to study L-type calcium channel function.

Moosmang S, Lenhardt P, Haider N, Hofmann F, Wegener JW.

Pharmacol Ther. 2005 Jun;106(3):347-55. Review.

PMID:
15922017
31.

An essential role of Cav1.2 L-type calcium channel for urinary bladder function.

Wegener JW, Schulla V, Lee TS, Koller A, Feil S, Feil R, Kleppisch T, Klugbauer N, Moosmang S, Welling A, Hofmann F.

FASEB J. 2004 Jul;18(10):1159-61. Epub 2004 May 7.

PMID:
15132976
32.

Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus.

Wegener JW, Lee M, Hofmann F.

Can J Physiol Pharmacol. 2003 Sep;81(9):890-3.

PMID:
14614526
33.

Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation.

Moosmang S, Schulla V, Welling A, Feil R, Feil S, Wegener JW, Hofmann F, Klugbauer N.

EMBO J. 2003 Nov 17;22(22):6027-34.

34.

Tenax extraction mimics benthic and terrestrial bioavailability of organic compounds.

ten Hulscher TE, Postma J, den Besten PJ, Stroomberg GJ, Belfroid A, Wegener JW, Faber JH, van der Pol JJ, Hendriks AJ, van Noort PC.

Environ Toxicol Chem. 2003 Oct;22(10):2258-65.

PMID:
14551987
35.

Voltage-dependent effects of barnidipine in rat vascular smooth muscle.

Wegener JW, Korstanje C, Nawrath H.

J Cardiovasc Pharmacol. 2003 Aug;42(2):218-23.

PMID:
12883325
36.

Imposex and organotin concentrations in Buccinum undatum and Neptunea antiqua from the North Sea: relationship to shipping density and hydrographical conditions.

ten Hallers-Tjabbes CC, Wegener JW, Van Hattum B, Kemp JF, ten Hallers E, Reitsemae TJ, Boon JP.

Mar Environ Res. 2003 Apr;55(3):203-33.

PMID:
12688240
37.
38.

Effects of nitric oxide donors on cardiac contractility in wild-type and myoglobin-deficient mice.

Wegener JW, Gödecke A, Schrader J, Nawrath H.

Br J Pharmacol. 2002 Jun;136(3):415-20.

39.

cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium.

Wegener JW, Nawrath H, Wolfsgruber W, Kühbandner S, Werner C, Hofmann F, Feil R.

Circ Res. 2002 Jan 11;90(1):18-20.

PMID:
11786513
40.

Increased cardiac alpha-1-adrenoceptor density in rats following treatment with amiodarone.

Budu CE, Balas N, Nawrath H, Wegener JW, Shainberg A.

J Basic Clin Physiol Pharmacol. 2001;12(1):33-47.

PMID:
11414506
41.

Voltage dependence of L-arginine transport by hCAT-2A and hCAT-2B expressed in oocytes from Xenopus laevis.

Nawrath H, Wegener JW, Rupp J, Habermeier A, Closs EI.

Am J Physiol Cell Physiol. 2000 Nov;279(5):C1336-44.

42.
43.

Barnidipine block of L-type Ca(2+) channel currents in rat ventricular cardiomyocytes.

Wegener JW, Meyrer H, Rupp J, Nawrath H.

Br J Pharmacol. 2000 Aug;130(8):2015-23.

44.

Involvement of K(+) channels in the relaxant effects of YC-1 in vascular smooth muscle.

Seitz S, Wegener JW, Rupp J, Watanabe M, Jost A, Gerhard R, Shainberg A, Ochi R, Nawrath H.

Eur J Pharmacol. 1999 Oct 1;382(1):11-8.

PMID:
10556499
45.
46.

Inhibition by fendiline of the transient outward current in rat ventricular cardiomyocytes.

Fassbender V, Wegener JW, Shainberg A, Nawrath H.

J Cardiovasc Pharmacol. 1999 Jun;33(6):905-11.

PMID:
10367594
47.

Mechanism of block by 4-aminopyridine of the transient outward current in rat ventricular cardiomyocytes.

Wegener JW, Peiter A, Sampson SR, Nawrath H.

J Cardiovasc Pharmacol. 1998 Jul;32(1):134-8.

PMID:
9676733
48.

Open state block by fendiline of L-type Ca++ channels in ventricular myocytes from rat heart.

Nawrath H, Klein G, Rupp J, Wegener JW, Shainberg A.

J Pharmacol Exp Ther. 1998 May;285(2):546-52.

PMID:
9580596
49.

Activation of soluble guanylyl cyclase by YC-1 in aortic smooth muscle but not in ventricular myocardium from rat.

Wegener JW, Gath I, Förstermann U, Nawrath H.

Br J Pharmacol. 1997 Dec;122(7):1523-9.

50.

Second messenger-controlled membrane conductance in locust (Locusta migratoria) olfactory neurons.

Breer H, Hanke W, Wegener JW.

J Insect Physiol. 1997 Jun;43(6):595-603.

PMID:
12770422

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