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Items: 1 to 50 of 293

1.

Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model.

Ribeiro DE, Casarotto PC, Staquini L, Pinto E Silva MA, Biojone C, Wegener G, Joca S.

PeerJ. 2019 Oct 21;7:e7834. doi: 10.7717/peerj.7834. eCollection 2019.

2.

Antidepressant-like effect induced by P2X7 receptor blockade in FSL rats is associated with BDNF signalling activation.

Ribeiro DE, Müller HK, Elfving B, Eskelund A, Joca SR, Wegener G.

J Psychopharmacol. 2019 Nov;33(11):1436-1446. doi: 10.1177/0269881119872173. Epub 2019 Sep 17.

PMID:
31526216
3.

Effect of ischemic lesions in medial prefrontal cortex and nucleus accumbens on affective behavior in rats.

Happ DF, Wegener G, Tasker RA.

Behav Brain Res. 2020 Jan 27;378:112234. doi: 10.1016/j.bbr.2019.112234. Epub 2019 Sep 12.

PMID:
31521735
4.

Anaerobic Degradation of Non-Methane Alkanes by "Candidatus Methanoliparia" in Hydrocarbon Seeps of the Gulf of Mexico.

Laso-Pérez R, Hahn C, van Vliet DM, Tegetmeyer HE, Schubotz F, Smit NT, Pape T, Sahling H, Bohrmann G, Boetius A, Knittel K, Wegener G.

MBio. 2019 Aug 20;10(4). pii: e01814-19. doi: 10.1128/mBio.01814-19.

5.

Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites.

Kohtala S, Theilmann W, Rosenholm M, Müller HK, Kiuru P, Wegener G, Yli-Kauhaluoma J, Rantamäki T.

Neuropharmacology. 2019 Oct;157:107684. doi: 10.1016/j.neuropharm.2019.107684. Epub 2019 Jun 25.

6.

Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression.

Pereira VS, Joca SRL, Harvey BH, Elfving B, Wegener G.

Acta Neuropsychiatr. 2019 Oct;31(5):258-265. doi: 10.1017/neu.2019.25.

PMID:
31230597
7.

Chronic mild stress induces anhedonic behavior and changes in glutamate release, BDNF trafficking and dendrite morphology only in stress vulnerable rats. The rapid restorative action of ketamine.

Tornese P, Sala N, Bonini D, Bonifacino T, La Via L, Milanese M, Treccani G, Seguini M, Ieraci A, Mingardi J, Nyengaard JR, Calza S, Bonanno G, Wegener G, Barbon A, Popoli M, Musazzi L.

Neurobiol Stress. 2019 Apr 2;10:100160. doi: 10.1016/j.ynstr.2019.100160. eCollection 2019 Feb.

8.

Inflammation, insulin resistance and neuroprogression in depression.

Leonard BE, Wegener G.

Acta Neuropsychiatr. 2019 Jun 12:1-9. doi: 10.1017/neu.2019.17. [Epub ahead of print]

PMID:
31186075
9.

P2X7 Receptor Signaling in Stress and Depression.

Ribeiro DE, Roncalho AL, Glaser T, Ulrich H, Wegener G, Joca S.

Int J Mol Sci. 2019 Jun 6;20(11). pii: E2778. doi: 10.3390/ijms20112778. Review.

10.

Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat.

Jefsen O, Højgaard K, Christiansen SL, Elfving B, Nutt DJ, Wegener G, Müller HK.

Acta Neuropsychiatr. 2019 Aug;31(4):213-219. doi: 10.1017/neu.2019.15. Epub 2019 May 20.

PMID:
31106729
11.

Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms.

Silote GP, Sartim A, Sales A, Eskelund A, Guimarães FS, Wegener G, Joca S.

J Chem Neuroanat. 2019 Jul;98:104-116. doi: 10.1016/j.jchemneu.2019.04.006. Epub 2019 Apr 27. Review.

PMID:
31039391
12.

S-Ketamine Reverses Hippocampal Dendritic Spine Deficits in Flinders Sensitive Line Rats Within 1 h of Administration.

Treccani G, Ardalan M, Chen F, Musazzi L, Popoli M, Wegener G, Nyengaard JR, Müller HK.

Mol Neurobiol. 2019 Nov;56(11):7368-7379. doi: 10.1007/s12035-019-1613-3. Epub 2019 Apr 29.

PMID:
31037646
13.

Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats.

Tillmann S, Skibdal HE, Christiansen SH, Gøtzsche CR, Hassan M, Mathé AA, Wegener G, Woldbye DPD.

Behav Brain Res. 2019 Jul 23;367:28-34. doi: 10.1016/j.bbr.2019.03.039. Epub 2019 Mar 23.

PMID:
30914309
14.

Prelimbic neuronal nitric oxide synthase inhibition exerts antidepressant-like effects independently of BDNF signalling cascades.

Pereira VS, Suavinha ACDR, Wegener G, Joca SRL.

Acta Neuropsychiatr. 2019 Jun;31(3):143-150. doi: 10.1017/neu.2018.39. Epub 2019 Mar 20.

PMID:
30890202
15.

Electroconvulsive stimulation differentially affects [11C]MDL100,907 binding to cortical and subcortical 5HT2A receptors in porcine brain.

Landau AM, Alstrup AKO, Noer O, Winterdahl M, Audrain H, Møller A, Videbech P, Wegener G, Gjedde A, Doudet DJ.

J Psychopharmacol. 2019 Jun;33(6):714-721. doi: 10.1177/0269881119836212. Epub 2019 Mar 19.

PMID:
30887871
16.

Acute Inescapable Stress Rapidly Increases Synaptic Energy Metabolism in Prefrontal Cortex and Alters Working Memory Performance.

Musazzi L, Sala N, Tornese P, Gallivanone F, Belloli S, Conte A, Di Grigoli G, Chen F, Ikinci A, Treccani G, Bazzini C, Castiglioni I, Nyengaard JR, Wegener G, Moresco RM, Popoli M.

Cereb Cortex. 2019 Mar 16. pii: bhz034. doi: 10.1093/cercor/bhz034. [Epub ahead of print]

PMID:
30877789
17.

Expanding anaerobic alkane metabolism in the domain of Archaea.

Wang Y, Wegener G, Hou J, Wang F, Xiao X.

Nat Microbiol. 2019 Apr;4(4):595-602. doi: 10.1038/s41564-019-0364-2. Epub 2019 Mar 4. Review.

PMID:
30833728
18.

Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli.

Hvilsom AST, Lillethorup TP, Iversen P, Doudet DJ, Wegener G, Landau AM.

Eur Neuropsychopharmacol. 2019 Apr;29(4):493-500. doi: 10.1016/j.euroneuro.2019.02.009. Epub 2019 Feb 28.

PMID:
30826156
19.

Decoding the Mechanism of Action of Rapid-Acting Antidepressant Treatment Strategies: Does Gender Matter?

Herzog DP, Wegener G, Lieb K, Müller MB, Treccani G.

Int J Mol Sci. 2019 Feb 22;20(4). pii: E949. doi: 10.3390/ijms20040949. Review.

20.

Latent toxoplasmosis aggravates anxiety- and depressive-like behaviour and suggest a role of gene-environment interactions in the behavioural response to the parasite.

Bay-Richter C, Petersen E, Liebenberg N, Elfving B, Wegener G.

Behav Brain Res. 2019 May 17;364:133-139. doi: 10.1016/j.bbr.2019.02.018. Epub 2019 Feb 12.

PMID:
30768994
21.

Behavioral and metabolic effects of S-adenosylmethionine and imipramine in the Flinders Sensitive Line rat model of depression.

Tillmann S, Happ DF, Mikkelsen PF, Geisel J, Wegener G, Obeid R.

Behav Brain Res. 2019 May 17;364:274-280. doi: 10.1016/j.bbr.2019.02.011. Epub 2019 Feb 6.

PMID:
30738101
22.

Hemisphere-dependent endocannabinoid system activity in prefrontal cortex and hippocampus of the Flinders Sensitive Line rodent model of depression.

Kirkedal C, Elfving B, Müller HK, Moreira FA, Bindila L, Lutz B, Wegener G, Liebenberg N.

Neurochem Int. 2019 May;125:7-15. doi: 10.1016/j.neuint.2019.01.023. Epub 2019 Feb 1.

PMID:
30716357
23.

Nitric oxide signalling and antidepressant action revisited.

Joca SRL, Sartim AG, Roncalho AL, Diniz CFA, Wegener G.

Cell Tissue Res. 2019 Jul;377(1):45-58. doi: 10.1007/s00441-018-02987-4. Epub 2019 Jan 16. Review.

PMID:
30649612
24.

Brain proteome changes in female Brd1+/- mice unmask dendritic spine pathology and show enrichment for schizophrenia risk.

Paternoster V, Svanborg M, Edhager AV, Rajkumar AP, Eickhardt EA, Pallesen J, Grove J, Qvist P, Fryland T, Wegener G, Nyengaard JR, Mors O, Palmfeldt J, Børglum AD, Christensen JH.

Neurobiol Dis. 2019 Apr;124:479-488. doi: 10.1016/j.nbd.2018.12.011. Epub 2018 Dec 24.

PMID:
30590179
25.

Latent toxoplasmosis and psychiatric symptoms - A role of tryptophan metabolism?

Bay-Richter C, Buttenschøn HN, Mors O, Eskelund A, Budac D, Kærlev L, Wegener G.

J Psychiatr Res. 2019 Mar;110:45-50. doi: 10.1016/j.jpsychires.2018.12.016. Epub 2018 Dec 17.

PMID:
30583085
26.

Anaerobic methane oxidation inducing carbonate precipitation at abiogenic methane seeps in the Tuscan archipelago (Italy).

Meister P, Wiedling J, Lott C, Bach W, Kuhfuß H, Wegener G, Böttcher ME, Deusner C, Lichtschlag A, Bernasconi SM, Weber M.

PLoS One. 2018 Dec 19;13(12):e0207305. doi: 10.1371/journal.pone.0207305. eCollection 2018.

27.

Altered fecal microbiota composition in the Flinders sensitive line rat model of depression.

Tillmann S, Abildgaard A, Winther G, Wegener G.

Psychopharmacology (Berl). 2019 May;236(5):1445-1457. doi: 10.1007/s00213-018-5094-2. Epub 2018 Nov 23.

28.

Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice.

Qvist P, Eskildsen SF, Hansen B, Baragji M, Ringgaard S, Roovers J, Paternoster V, Molgaard S, Corydon TJ, Stødkilde-Jørgensen H, Glerup S, Mors O, Wegener G, Nyengaard JR, Børglum AD, Christensen JH.

Sci Rep. 2018 Nov 7;8(1):16486. doi: 10.1038/s41598-018-34729-5.

29.

The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats.

Abildgaard A, Kern T, Pedersen O, Hansen T, Wegener G, Lund S.

Eur Neuropsychopharmacol. 2019 Jan;29(1):98-110. doi: 10.1016/j.euroneuro.2018.10.011. Epub 2018 Nov 2.

PMID:
30396698
30.

Grandmaternal high-fat diet primed anxiety-like behaviour in the second-generation female offspring.

Winther G, Eskelund A, Bay-Richter C, Elfving B, Müller HK, Lund S, Wegener G.

Behav Brain Res. 2019 Feb 1;359:47-55. doi: 10.1016/j.bbr.2018.10.017. Epub 2018 Oct 15.

PMID:
30336180
31.

Probiotics reduce risk-taking behavior in the Elevated Plus Maze in the Flinders Sensitive Line rat model of depression.

Tillmann S, Wegener G.

Behav Brain Res. 2019 Feb 1;359:755-762. doi: 10.1016/j.bbr.2018.08.025. Epub 2018 Aug 28.

PMID:
30170032
32.

Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood.

Winther G, Elfving B, Müller HK, Lund S, Wegener G.

Neuroscience. 2018 Sep 15;388:87-101. doi: 10.1016/j.neuroscience.2018.07.014. Epub 2018 Jul 17.

PMID:
30025860
33.

Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex.

Sales AJ, Fogaça MV, Sartim AG, Pereira VS, Wegener G, Guimarães FS, Joca SRL.

Mol Neurobiol. 2019 Feb;56(2):1070-1081. doi: 10.1007/s12035-018-1143-4. Epub 2018 Jun 4.

PMID:
29869197
34.

Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression.

Sanchez C, El Khoury A, Hassan M, Wegener G, Mathé AA.

Behav Brain Res. 2018 Oct 1;351:93-103. doi: 10.1016/j.bbr.2018.05.029. Epub 2018 May 29.

PMID:
29857028
35.

Establishing anaerobic hydrocarbon-degrading enrichment cultures of microorganisms under strictly anoxic conditions.

Laso-Pérez R, Krukenberg V, Musat F, Wegener G.

Nat Protoc. 2018 Jun;13(6):1310-1330. doi: 10.1038/nprot.2018.030. Epub 2018 May 17.

PMID:
29773905
36.

A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania.

Liebenberg N, Jensen E, Larsen ER, Kousholt BS, Pereira VS, Fischer CW, Wegener G.

Int J Neuropsychopharmacol. 2018 May 1;21(5):473-484. doi: 10.1093/ijnp/pyy012.

37.

A Critical Role of Mitochondria in BDNF-Associated Synaptic Plasticity After One-Week Vortioxetine Treatment.

Chen F, Danladi J, Ardalan M, Elfving B, Müller HK, Wegener G, Sanchez C, Nyengaard JR.

Int J Neuropsychopharmacol. 2018 Jun 1;21(6):603-615. doi: 10.1093/ijnp/pyy022.

38.

Gene expression and ultrastructure of meso- and thermophilic methanotrophic consortia.

Krukenberg V, Riedel D, Gruber-Vodicka HR, Buttigieg PL, Tegetmeyer HE, Boetius A, Wegener G.

Environ Microbiol. 2018 May;20(5):1651-1666. doi: 10.1111/1462-2920.14077. Epub 2018 Apr 11.

39.

Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression.

Tillmann S, Awwad HM, Eskelund AR, Treccani G, Geisel J, Wegener G, Obeid R.

Mol Nutr Food Res. 2018 Apr;62(7):e1701070. doi: 10.1002/mnfr.201701070. Epub 2018 Mar 13.

40.

CO2 leakage alters biogeochemical and ecological functions of submarine sands.

Molari M, Guilini K, Lott C, Weber M, de Beer D, Meyer S, Ramette A, Wegener G, Wenzhöfer F, Martin D, Cibic T, De Vittor C, Vanreusel A, Boetius A.

Sci Adv. 2018 Feb 7;4(2):eaao2040. doi: 10.1126/sciadv.aao2040. eCollection 2018 Feb.

41.

S-Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression.

du Jardin KG, Liebenberg N, Cajina M, Müller HK, Elfving B, Sanchez C, Wegener G.

Front Pharmacol. 2018 Jan 15;8:978. doi: 10.3389/fphar.2017.00978. eCollection 2017.

42.

Syringe-feeding as a novel delivery method for accurate individual dosing of probiotics in rats.

Tillmann S, Wegener G.

Benef Microbes. 2018 Feb 27;9(2):311-315. doi: 10.3920/BM2017.0127. Epub 2017 Dec 21.

PMID:
29264968
43.

Mitochondria Are Critical for BDNF-Mediated Synaptic and Vascular Plasticity of Hippocampus following Repeated Electroconvulsive Seizures.

Chen F, Ardalan M, Elfving B, Wegener G, Madsen TM, Nyengaard JR.

Int J Neuropsychopharmacol. 2018 Mar 1;21(3):291-304. doi: 10.1093/ijnp/pyx115.

44.

Acta Neuropsychiatrica and social media.

Wegener G.

Acta Neuropsychiatr. 2017 Dec;29(6):323. doi: 10.1017/neu.2017.30. No abstract available.

PMID:
29151405
45.

The microbial metabolite indole-3-propionic acid improves glucose metabolism in rats, but does not affect behaviour.

Abildgaard A, Elfving B, Hokland M, Wegener G, Lund S.

Arch Physiol Biochem. 2018 Oct;124(4):306-312. doi: 10.1080/13813455.2017.1398262. Epub 2017 Nov 7.

PMID:
29113509
46.

Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats.

Silva Pereira V, Elfving B, Joca SRL, Wegener G.

Eur J Pharmacol. 2017 Nov 15;815:304-311. doi: 10.1016/j.ejphar.2017.09.029. Epub 2017 Sep 22.

PMID:
28947331
47.

Impact of Time Factors on Outcome in Patients with Head and Neck Cancer Treated with Definitive Radio(Chemo)Therapy.

Dahlke S, Steinmann D, Christiansen H, Durisin M, Eckardt A, Wegener G, Bremer M, Meyer A.

In Vivo. 2017 Sep-Oct;31(5):949-955.

48.

Discovery versus implementation research on mental disorders in low- and middle-income countries.

Stein DJ, Wegener G.

Acta Neuropsychiatr. 2017 Aug;29(4):191-192. doi: 10.1017/neu.2017.25. Epub 2017 Aug 10. No abstract available.

PMID:
28793939
49.

ZL006, a small molecule inhibitor of PSD-95/nNOS interaction, does not induce antidepressant-like effects in two genetically predisposed rat models of depression and control animals.

Tillmann S, Pereira VS, Liebenberg N, Christensen AK, Wegener G.

PLoS One. 2017 Aug 3;12(8):e0182698. doi: 10.1371/journal.pone.0182698. eCollection 2017.

50.

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