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Items: 44

1.

Nicotinic alpha 7 receptor agonists EVP-6124 and BMS-933043, attenuate scopolamine-induced deficits in visuo-spatial paired associates learning.

Weed MR, Polino J, Signor L, Bookbinder M, Keavy D, Benitex Y, Morgan DG, King D, Macor JE, Zaczek R, Olson R, Bristow LJ.

PLoS One. 2017 Dec 19;12(12):e0187609. doi: 10.1371/journal.pone.0187609. eCollection 2017.

2.

Dosing, collection, and quality control issues in cerebrospinal fluid research using animal models.

Barten DM, Cadelina GW, Weed MR.

Handb Clin Neurol. 2017;146:47-64. doi: 10.1016/B978-0-12-804279-3.00004-6. Review.

PMID:
29110779
3.

Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder.

Bristow LJ, Gulia J, Weed MR, Srikumar BN, Li YW, Graef JD, Naidu PS, Sanmathi C, Aher J, Bastia T, Paschapur M, Kalidindi N, Kumar KV, Molski T, Pieschl R, Fernandes A, Brown JM, Sivarao DV, Newberry K, Bookbinder M, Polino J, Keavy D, Newton A, Shields E, Simmermacher J, Kempson J, Li J, Zhang H, Mathur A, Kallem RR, Sinha M, Ramarao M, Vikramadithyan RK, Thangathirupathy S, Warrier J, Islam I, Bronson JJ, Olson RE, Macor JE, Albright CF, King D, Thompson LA, Marcin LR, Sinz M.

J Pharmacol Exp Ther. 2017 Dec;363(3):377-393. doi: 10.1124/jpet.117.242784. Epub 2017 Sep 27.

PMID:
28954811
4.

B-973, a novel piperazine positive allosteric modulator of the α7 nicotinic acetylcholine receptor.

Post-Munson DJ, Pieschl RL, Molski TF, Graef JD, Hendricson AW, Knox RJ, McDonald IM, Olson RE, Macor JE, Weed MR, Bristow LJ, Kiss L, Ahlijanian MK, Herrington J.

Eur J Pharmacol. 2017 Mar 15;799:16-25. doi: 10.1016/j.ejphar.2017.01.037. Epub 2017 Jan 26.

PMID:
28132910
5.

The qEEG Signature of Selective NMDA NR2B Negative Allosteric Modulators; A Potential Translational Biomarker for Drug Development.

Keavy D, Bristow LJ, Sivarao DV, Batchelder M, King D, Thangathirupathy S, Macor JE, Weed MR.

PLoS One. 2016 Apr 1;11(4):e0152729. doi: 10.1371/journal.pone.0152729. eCollection 2016.

6.

Discovery of D1 Dopamine Receptor Positive Allosteric Modulators: Characterization of Pharmacology and Identification of Residues that Regulate Species Selectivity.

Lewis MA, Hunihan L, Watson J, Gentles RG, Hu S, Huang Y, Bronson J, Macor JE, Beno BR, Ferrante M, Hendricson A, Knox RJ, Molski TF, Kong Y, Cvijic ME, Rockwell KL, Weed MR, Cacace AM, Westphal RS, Alt A, Brown JM.

J Pharmacol Exp Ther. 2015 Sep;354(3):340-9. doi: 10.1124/jpet.115.224071. Epub 2015 Jun 24.

PMID:
26109678
7.

Negative Allosteric Modulators Selective for The NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.

Weed MR, Bookbinder M, Polino J, Keavy D, Cardinal RN, Simmermacher-Mayer J, Cometa FN, King D, Thangathirupathy S, Macor JE, Bristow LJ.

Neuropsychopharmacology. 2016 Jan;41(2):568-77. doi: 10.1038/npp.2015.184. Epub 2015 Jun 24.

8.

Neurocognitive dysfunction and pharmacological intervention using guanfacine in a rhesus macaque model of self-injurious behavior.

Freeman ZT, Rice KA, Soto PL, Pate KA, Weed MR, Ator NA, DeLeon IG, Wong DF, Zhou Y, Mankowski JL, Zink MC, Adams RJ, Hutchinson EK.

Transl Psychiatry. 2015 May 19;5:e567. doi: 10.1038/tp.2015.61.

9.

Effects of X-ray radiation on complex visual discrimination learning and social recognition memory in rats.

Davis CM, Roma PG, Armour E, Gooden VL, Brady JV, Weed MR, Hienz RD.

PLoS One. 2014 Aug 6;9(8):e104393. doi: 10.1371/journal.pone.0104393. eCollection 2014.

10.

Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].

Soto PL, Ator NA, Rallapalli SK, Biawat P, Clayton T, Cook JM, Weed MR.

Neuropsychopharmacology. 2013 Oct;38(11):2315-25. doi: 10.1038/npp.2013.137. Epub 2013 May 31. Erratum in: Neuropsychopharmacology. 2013 Nov;38(12):2553.

11.

Long-term exposure to oral methylphenidate or dl-amphetamine mixture in peri-adolescent rhesus monkeys: effects on physiology, behavior, and dopamine system development.

Soto PL, Wilcox KM, Zhou Y, Kumar A, Ator NA, Riddle MA, Wong DF, Weed MR.

Neuropsychopharmacology. 2012 Nov;37(12):2566-79. doi: 10.1038/npp.2012.119. Epub 2012 Jul 18. Erratum in: Neuropsychopharmacology. 2013 May;38(6):1141. Kumar, Anil [added].

12.

Cognitive development in macaques: attentional set-shifting in juvenile and adult rhesus monkeys.

Weed MR, Bryant R, Perry S.

Neuroscience. 2008 Nov 11;157(1):22-8. doi: 10.1016/j.neuroscience.2008.08.047. Epub 2008 Aug 31.

PMID:
18805462
13.

Blood levels and DA transporter occupancy of orally administered methylphenidate in juvenile rhesus monkeys measured by high resolution PET.

Wilcox KM, Zhou Y, Wong DF, Alexander M, Rahmim A, Hilton J, Weed MR.

Synapse. 2008 Dec;62(12):950-2. doi: 10.1002/syn.20565. No abstract available.

14.

A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.

Han D, Holger Försterling F, Li X, Deschamps JR, Parrish D, Cao H, Rallapalli S, Clayton T, Teng Y, Majumder S, Sankar S, Roth BL, Sieghart W, Furtmuller R, Rowlett JK, Weed MR, Cook JM.

Bioorg Med Chem. 2008 Oct 1;16(19):8853-62. doi: 10.1016/j.bmc.2008.08.072. Epub 2008 Sep 2.

15.

Neurobehavioral effects of head-only gamma-radiation exposure in rats.

Hienz RD, Brady JV, Gooden VL, Vazquez ME, Weed MR.

Radiat Res. 2008 Sep;170(3):292-8. doi: 10.1667/RR1222.1.

PMID:
18763858
16.

Consistent, high-level ethanol consumption in pig-tailed macaques via a multiple-session, limited-intake, oral self-dosing procedure.

Weed MR, Wilcox KM, Ator NA, Hienz RD.

Alcohol Clin Exp Res. 2008 Jun;32(6):942-51. doi: 10.1111/j.1530-0277.2008.00652.x. Epub 2008 Apr 26.

PMID:
18445107
17.

Morphine withdrawal dramatically reduces lymphocytes in morphine-dependent macaques.

Weed MR, Carruth LM, Adams RJ, Ator NA, Hienz RD.

J Neuroimmune Pharmacol. 2006 Sep;1(3):250-9. Epub 2006 Jul 14.

PMID:
18040802
18.

Impaired performance on the object retrieval-detour test of executive function in the SIV/macaque model of AIDS.

Gray RA, Wilcox KM, Zink MC, Weed MR.

AIDS Res Hum Retroviruses. 2006 Oct;22(10):1031-5.

PMID:
17067274
19.

Effects of morphine on circadian rhythms of motor activity and body temperature in pig-tailed macaques.

Weed MR, Hienz RD.

Pharmacol Biochem Behav. 2006 Jul;84(3):487-96. Epub 2006 Jul 21.

PMID:
16860378
20.

Neuropsychopathology in the SIV/macaque model of AIDS.

Weed MR, Steward DJ.

Front Biosci. 2005 Jan 1;10:710-27. Print 2005 Jan 1. Review.

PMID:
15569612
21.
22.

Impaired performance on a rhesus monkey neuropsychological testing battery following simian immunodeficiency virus infection.

Weed MR, Gold LH, Polis I, Koob GF, Fox HS, Taffe MA.

AIDS Res Hum Retroviruses. 2004 Jan;20(1):77-89.

PMID:
15000701
23.

Central nervous system correlates of behavioral deficits following simian immunodeficiency virus infection.

Weed MR, Hienz RD, Brady JV, Adams RJ, Mankowski JL, Clements JE, Zink MC.

J Neurovirol. 2003 Aug;9(4):452-64.

PMID:
12907390
24.

Cocaine's effects on detection, discrimination, and identification of auditory stimuli by baboons.

Hienz RD, Weed MR, Zarcone TJ, Brady JV.

Pharmacol Biochem Behav. 2003 Jan;74(2):287-96.

PMID:
12479947
25.

Cocaine's effects on the discrimination of simple and complex auditory stimuli by baboons.

Hienz RD, Weed MR, Zarcone TJ, Brady JV.

Pharmacol Biochem Behav. 2002 Jul;72(4):825-33.

PMID:
12062572
26.

Differential muscarinic and NMDA contributions to visuo-spatial paired-associate learning in rhesus monkeys.

Taffe MA, Weed MR, Gutierrez T, Davis SA, Gold LH.

Psychopharmacology (Berl). 2002 Mar;160(3):253-62. Epub 2002 Jan 22.

27.

Paradigms for behavioral assessment of viral pathogenesis.

Weed MR, Gold LH.

Adv Virus Res. 2001;56:583-626. Review. No abstract available.

PMID:
11450313
28.

Functional consequences of repeated (+/-)3,4-methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys.

Taffe MA, Weed MR, Davis S, Huitrón-Resendiz S, Schroeder R, Parsons LH, Henriksen SJ, Gold LH.

Neuropsychopharmacology. 2001 Mar;24(3):230-9.

29.

Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus-infected monkeys.

Fox HS, Weed MR, Huitron-Resendiz S, Baig J, Horn TF, Dailey PJ, Bischofberger N, Henriksen SJ.

J Clin Invest. 2000 Jul;106(1):37-45.

30.

Scopolamine alters rhesus monkey performance on a novel neuropsychological test battery.

Taffe MA, Weed MR, Gold LH.

Brain Res Cogn Brain Res. 1999 Oct 25;8(3):203-12.

PMID:
10556599
31.

Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance.

Weed MR, Taffe MA, Polis I, Roberts AC, Robbins TW, Koob GF, Bloom FE, Gold LH.

Brain Res Cogn Brain Res. 1999 Oct 25;8(3):185-201.

PMID:
10556598
32.

Dopamine D1 and D2 receptor selectivities of phenyl-benzazepines in rhesus monkey striata.

Weed MR, Woolverton WL, Paul IA.

Eur J Pharmacol. 1998 Nov 13;361(1):129-42.

PMID:
9851550
33.

Early physiological abnormalities after simian immunodeficiency virus infection.

Horn TF, Huitron-Resendiz S, Weed MR, Henriksen SJ, Fox HS.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15072-7.

34.

Longitudinal analysis of behavioral, neurophysiological, viral and immunological effects of SIV infection in rhesus monkeys.

Gold LH, Fox HS, Henriksen SJ, Buchmeier MJ, Weed MR, Taffe MA, Huitrón-Resendiz S, Horn TF, Bloom FE.

J Med Primatol. 1998 Apr-Jun;27(2-3):104-12.

PMID:
9747951
35.

The effects of dopaminergic agents on reaction time in rhesus monkeys.

Weed MR, Gold LH.

Psychopharmacology (Berl). 1998 May;137(1):33-42.

PMID:
9631954
36.

Choice between cocaine and food in a discrete-trials procedure in monkeys: a unit price analysis.

Woolverton WL, English JA, Weed MR.

Psychopharmacology (Berl). 1997 Oct;133(3):269-74.

PMID:
9361333
37.

The relationship between reinforcing effects and in vitro effects of D1 agonists in monkeys.

Weed MR, Paul IA, Dwoskin LP, Moore SE, Woolverton WL.

J Pharmacol Exp Ther. 1997 Oct;283(1):29-38.

PMID:
9336305
38.

The reinforcing effects of dopamine D1 receptor agonists in rhesus monkeys.

Weed MR, Woolverton WL.

J Pharmacol Exp Ther. 1995 Dec;275(3):1367-74.

PMID:
8531104
39.

Reinforcing and discriminative stimulus effects of beta-CIT in rhesus monkeys.

Weed MR, Mackevicius AS, Kebabian J, Woolverton WL.

Pharmacol Biochem Behav. 1995 Aug;51(4):953-6.

PMID:
7675883
40.

Evening alcohol consumption alters the circadian rhythm of body temperature.

Eastman CI, Stewart KT, Weed MR.

Chronobiol Int. 1994 Apr;11(2):141-2. No abstract available.

PMID:
7741832
41.

Reinforcing effect of the D1 dopamine agonist SKF 81297 in rhesus monkeys.

Weed MR, Vanover KE, Woolverton WL.

Psychopharmacology (Berl). 1993;113(1):51-2.

PMID:
7862828
42.

The shortage of pathologists.

WEED MR.

Am J Clin Pathol. 1954 Jan;24(1):74-6. No abstract available.

PMID:
13124276
43.

d-Tubocurarine in wax and oil for control of muscle spasm in tetanus.

WEED MR, PURVIS DF, WARNKE RD.

J Am Med Assoc. 1948 Dec 11;138(15):1087-90. No abstract available.

PMID:
18894112
44.

Treatment of tetanus.

SMATHERS HM, WEED MR.

Arch Surg. 1948 Sep;57(3):291-300. No abstract available.

PMID:
18102755

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