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Prognostic factors of oligometastatic non-small-cell lung cancer following radical therapy: a multicentre analysis.

Opitz I, Patella M, Payrard L, Perentes JY, Inderbitzi R, Gelpke H, Schulte S, Diezi M, Gonzalez M, Krueger T, Weder W.

Eur J Cardiothorac Surg. 2020 Feb 3. pii: ezz384. doi: 10.1093/ejcts/ezz384. [Epub ahead of print]



Travis WD, Dacic S, Wistuba I, Sholl L, Adusumilli P, Bubendorf L, Bunn P, Cascone T, Chaft J, Chen G, Chou TY, Cooper W, Erasmus JJ, Ferreira CG, Goo JM, Heymach J, Hirsch FR, Horinouchi H, Kerr K, Kris M, Jain D, Kim YT, Lopez-Rios F, Lu S, Mitsudomi T, Moreira A, Motoi N, Nicholson AG, Oliveira R, Papotti M, Pastorino U, Paz-Ares L, Pelosi G, Poleri C, Provencio M, Roden AC, Scagliotti G, Swisher SG, Thunnissen E, Tsao MS, Vansteenkiste J, Weder W, Yatabe Y.

J Thorac Oncol. 2020 Jan 28. pii: S1556-0864(20)30026-5. doi: 10.1016/j.jtho.2020.01.005. [Epub ahead of print] Review.


Complex sleeve lobectomy has the same surgical outcome when compared with conventional lobectomy in patients with lung cancer.

Inci I, Benker M, Çitak N, Schneiter D, Caviezel C, Hillinger S, Opitz I, Weder W.

Eur J Cardiothorac Surg. 2020 Jan 9. pii: ezz357. doi: 10.1093/ejcts/ezz357. [Epub ahead of print]


Predictors of blood loss in lung transplant surgery-a single center retrospective cohort analysis.

Grande B, Oechslin P, Schlaepfer M, Seifert B, Inci I, Opitz I, Spahn DR, Weder W, Zalunardo M.

J Thorac Dis. 2019 Nov;11(11):4755-4761. doi: 10.21037/jtd.2019.10.61.


Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition.

Okonska A, Bühler S, Rao V, Ronner M, Blijlevens M, van der Meulen-Muileman IH, de Menezes RX, Wipplinger M, Oehl K, Smit EF, Weder W, Stahel RA, Penengo L, van Beusechem VW, Felley-Bosco E.

Mol Cancer Ther. 2020 Feb;19(2):552-563. doi: 10.1158/1535-7163.MCT-19-0356. Epub 2019 Oct 16.


Stereotactic Body Radiation Therapy (SBRT) as Salvage Therapy for Oligorecurrent Pleural Mesothelioma After Multi-Modality Therapy.

Schröder C, Opitz I, Guckenberger M, Stahel R, Weder W, Förster R, Andratschke N, Lauk O.

Front Oncol. 2019 Sep 26;9:961. doi: 10.3389/fonc.2019.00961. eCollection 2019.


Perioperative course and quality of life in a prospective randomized multicenter phase III trial, comparing standard lobectomy versus anatomical segmentectomy in patients with non-small cell lung cancer up to 2 cm, stage IA (7th edition of TNM staging system).

Stamatis G, Leschber G, Schwarz B, Brintrup DL, Ose C, Weinreich G, Passlick B, Hecker E, Kugler C, Dienemann H, Krbek T, Eggeling S, Hatz R, Müller MR, Weder W, Aigner C, Jöckel KH.

Lung Cancer. 2019 Dec;138:19-26. doi: 10.1016/j.lungcan.2019.09.021. Epub 2019 Sep 27.


Intracavitary cisplatin-fibrin chemotherapy after surgery for malignant pleural mesothelioma: A phase I trial.

Opitz I, Lauk O, Meerang M, Jetter A, Aeschlimann B, Seifert B, Günther D, Stahel RA, Weder W.

J Thorac Cardiovasc Surg. 2019 Aug 22. pii: S0022-5223(19)31613-7. doi: 10.1016/j.jtcvs.2019.07.073. [Epub ahead of print]


Surgical Outcomes and Risk Analysis of Primary Pulmonary Sarcoma.

Yamada Y, Kaplan T, Soltermann A, Schmitt-Opitz I, Schneiter D, Weder W, Inci I.

Thorac Cardiovasc Surg. 2019 Sep 9. doi: 10.1055/s-0039-1695784. [Epub ahead of print]


Hybrid nanocomposite as a chest wall graft with improved integration by adipose-derived stem cells.

Buschmann J, Yamada Y, Schulz-Schönhagen K, Hess SC, Stark WJ, Opelz C, Bürgisser GM, Weder W, Jungraithmayr W.

Sci Rep. 2019 Jul 29;9(1):10910. doi: 10.1038/s41598-019-47441-9.


Adjuvant Chemotherapy Increases Programmed Death-Ligand 1 (PD-L1) Expression in Non-small Cell Lung Cancer Recurrence.

Lacour M, Hiltbrunner S, Lee SY, Soltermann A, Rushing EJ, Soldini D, Weder W, Curioni-Fontecedro A.

Clin Lung Cancer. 2019 Sep;20(5):391-396. doi: 10.1016/j.cllc.2019.05.013. Epub 2019 Jun 5.


Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.

Riesterer O, Ciernik IF, Stahel RA, Xyrafas A, Aebersold DM, Plasswilm L, Mahmut Ozsahin E, Zwahlen DR, Nackaerts K, Zimmermann F, Sabrina Stark L, Weder W, Krayenbuehl J; Swiss Group for Clinical Cancer Research (SAKK).

Radiother Oncol. 2019 Sep;138:121-125. doi: 10.1016/j.radonc.2019.05.024. Epub 2019 Jun 25.


miR-625-3p and lncRNA GAS5 in Liquid Biopsies for Predicting the Outcome of Malignant Pleural Mesothelioma Patients Treated with Neo-Adjuvant Chemotherapy and Surgery.

Kresoja-Rakic J, Szpechcinski A, Kirschner MB, Ronner M, Minatel B, Martinez VD, Lam WL, Weder W, Stahel R, Früh M, Cerciello F, Felley-Bosco E.

Noncoding RNA. 2019 Jun 17;5(2). pii: E41. doi: 10.3390/ncrna5020041.


A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project.

Kerr KM, Thunnissen E, Dafni U, Finn SP, Bubendorf L, Soltermann A, Verbeken E, Biernat W, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM, Monkhorst K, Navarro A, Madsen LB, Radonic T, Wilson J, De Luca G, Gray SG, Cheney R, Savic S, Martorell M, Muley T, Baas P, Meldgaard P, Blackhall F, Dingemans AM, Dziadziuszko R, Vansteenkiste J, Weder W, Polydoropoulou V, Geiger T, Kammler R, Peters S, Stahel R; Lungscape Consortium.

Lung Cancer. 2019 May;131:95-103. doi: 10.1016/j.lungcan.2019.03.012. Epub 2019 Mar 15.


Applicability of color-coded computed tomography images in lung volume reduction surgery planning.

Muehlematter UJ, Caviezel C, Martini K, Messerli M, Vokinger KN, Wetzler IR, Tutic-Horn M, Weder W, Frauenfelder T.

J Thorac Dis. 2019 Mar;11(3):766-776. doi: 10.21037/jtd.2019.02.36.


Establishing a non-intubated thoracoscopic surgery programme for bilateral uniportal sympathectomy.

Caviezel C, Schuepbach R, Grande B, Opitz I, Zalunardo M, Weder W, Hillinger S.

Swiss Med Wkly. 2019 Apr 17;149:w20064. doi: 10.4414/smw.2019.20064. eCollection 2019 Apr 8.


Preoperative chemotherapy and radiotherapy concomitant to cetuximab in resectable stage IIIB NSCLC: a multicentre phase 2 trial (SAKK 16/08).

Curioni-Fontecedro A, Perentes JY, Gelpke H, Xyrafas A, Bouchaab H, Mach N, Matzinger O, Stojcheva N, Frueh M, Weder W, Cathomas R, Gargiulo P, Bubendorf L, Pless M, Betticher D, Peters S; Swiss Group of Clinical Cancer Research (SAKK).

Br J Cancer. 2019 May;120(10):968-974. doi: 10.1038/s41416-019-0447-0. Epub 2019 Apr 16.


Surgical and endoscopic interventions that reduce lung volume for emphysema: a systemic review and meta-analysis.

van Geffen WH, Slebos DJ, Herth FJ, Kemp SV, Weder W, Shah PL.

Lancet Respir Med. 2019 Apr;7(4):313-324. doi: 10.1016/S2213-2600(18)30431-4. Epub 2019 Feb 8.


The Amide Local Anesthetic Ropivacaine Attenuates Acute Rejection After Allogeneic Mouse Lung Transplantation.

Maeyashiki T, Jang JH, Janker F, Yamada Y, Inci I, Weder W, Piegeler T, Jungraithmayr W.

Lung. 2019 Apr;197(2):217-226. doi: 10.1007/s00408-019-00197-5. Epub 2019 Feb 9.


The CD26/DPP4-inhibitor vildagliptin suppresses lung cancer growth via macrophage-mediated NK cell activity.

Jang JH, Janker F, De Meester I, Arni S, Borgeaud N, Yamada Y, Gil Bazo I, Weder W, Jungraithmayr W.

Carcinogenesis. 2019 Apr 29;40(2):324-334. doi: 10.1093/carcin/bgz009.


Report from the European Society of Thoracic Surgeons prospective thymic database 2017: a powerful resource for a collaborative global effort to manage thymic tumours.

Ruffini E, Guerrera F, Brunelli A, Passani S, Pellicano D, Thomas P, Van Raemdonck D, Rocco G, Venuta F, Weder W, Detterbeck F, Falcoz PE.

Eur J Cardiothorac Surg. 2019 Apr 1;55(4):601-609. doi: 10.1093/ejcts/ezy448.


Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.

Román M, López I, Guruceaga E, Baraibar I, Ecay M, Collantes M, Nadal E, Vallejo A, Cadenas S, Miguel ME, Jang JH, Martin-Uriz PS, Castro-Labrador L, Vilas-Zornoza A, Lara-Astiaso D, Ponz-Sarvise M, Rolfo C, Santos ES, Raez LE, Taverna S, Behrens C, Weder W, Wistuba II, Vicent S, Gil-Bazo I.

Cancer Res. 2019 Feb 1;79(3):625-638. doi: 10.1158/0008-5472.CAN-18-1479. Epub 2018 Dec 18.


The American Society of Clinical Oncology-endorsed American Society for Radiation Oncology Evidence-Based Guideline of stereotactic body radiotherapy for early-stage non-small cell lung cancer: An expert opinion.

Guckenberger M, Aerts JG, Van Schil P, Weder W.

J Thorac Cardiovasc Surg. 2019 Jan;157(1):358-361. doi: 10.1016/j.jtcvs.2018.09.107. Epub 2018 Oct 12. No abstract available. Erratum in: J Thorac Cardiovasc Surg. 2019 Jun;157(6):2549.


Nonintubated surgical biopsy of undetermined interstitial lung disease: a multicentre outcome analysis.

Pompeo E, Rogliani P, Atinkaya C, Guerrera F, Ruffini E, Iñiguez-Garcia MA, Peer M, Voltolini L, Caviezel C, Weder W, Opitz I, Cavalli F, Sorge R; ESTS awake thoracic surgery working group.

Interact Cardiovasc Thorac Surg. 2019 May 1;28(5):744-750. doi: 10.1093/icvts/ivy320.


Intraluminal EWSR1-CREB1 gene rearranged, low-grade myxoid sarcoma of the pulmonary artery resembling extraskeletal myxoid chondrosarcoma (EMC).

Opitz I, Lauk O, Schneiter D, Ulrich S, Maisano F, Weder W, Bode-Lesniewska B.

Histopathology. 2019 Feb;74(3):526-530. doi: 10.1111/his.13773. Epub 2018 Dec 5. No abstract available.


Multimodal Treatment in Operable Stage III NSCLC: A Pooled Analysis on Long-Term Results of Three SAKK trials (SAKK 16/96, 16/00, and 16/01).

Früh M, Betticher DC, Stupp R, Xyrafas A, Peters S, Ris HB, Mirimanoff RO, Ochsenbein AF, Schmid R, Matzinger O, Stahel RA, Weder W, Guckenberger M, Rothschild SI, Lardinois D, Mach N, Mark M, Gautschi O, Thierstein S, Biaggi Rudolf C, Pless M; Swiss Group for Clinical Cancer Research (SAKK).

J Thorac Oncol. 2019 Jan;14(1):115-123. doi: 10.1016/j.jtho.2018.09.011. Epub 2018 Sep 26.


Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort.

Rulle U, Tsourti Z, Casanova R, Deml KF, Verbeken E, Thunnissen E, Warth A, Cheney R, Sejda A, Speel EJ, Madsen LB, Nonaka D, Navarro A, Sansano I, Marchetti A, Finn SP, Monkhorst K, Kerr KM, Haberecker M, Wu C, Zygoura P, Kammler R, Geiger T, Gendreau S, Schulze K, Vrugt B, Wild P, Moch H, Weder W, Ciftlik AT, Dafni U, Peters S, Bubendorf L, Stahel RA, Soltermann A.

J Thorac Oncol. 2018 Dec;13(12):1851-1863. doi: 10.1016/j.jtho.2018.08.2034. Epub 2018 Sep 18.


Postoperative complications and management after lung volume reduction surgery.

Lacour M, Caviezel C, Weder W, Schneiter D.

J Thorac Dis. 2018 Aug;10(Suppl 23):S2775-S2779. doi: 10.21037/jtd.2018.08.75. Review.


Lung volume reduction surgery beyond the NETT selection criteria.

Caviezel C, Schneiter D, Opitz I, Weder W.

J Thorac Dis. 2018 Aug;10(Suppl 23):S2748-S2753. doi: 10.21037/jtd.2018.08.93. Review.


Improved postoperative lung function after sublobar resection of non-small-cell lung cancer combined with lung volume reduction surgery in patients with advanced emphysema.

Caviezel C, von Rotz J, Schneiter D, Inci I, Hillinger S, Opitz I, Weder W.

J Thorac Dis. 2018 Aug;10(Suppl 23):S2704-S2710. doi: 10.21037/jtd.2018.06.79.


Lung volume reduction-a great chance for emphysema patients!

Franzen DP, Weder W.

J Thorac Dis. 2018 Aug;10(Suppl 23):S2696-S2697. doi: 10.21037/jtd.2018.04.144. No abstract available.


Gemcitabine Synergizes with Immune Checkpoint Inhibitors and Overcomes Resistance in a Preclinical Model and Mesothelioma Patients.

Tallón de Lara P, Cecconi V, Hiltbrunner S, Yagita H, Friess M, Bode B, Opitz I, Vrugt B, Weder W, Stolzmann P, Felley-Bosco E, Stahel RA, Tischler V, Britschgi C, Soldini D, van den Broek M, Curioni-Fontecedro A.

Clin Cancer Res. 2018 Dec 15;24(24):6345-6354. doi: 10.1158/1078-0432.CCR-18-1231. Epub 2018 Aug 28.


Dynamic magnetic resonance imaging as an outcome predictor for lung-volume reduction surgery in patients with severe emphysema†.

Martini K, Caviezel C, Schneiter D, Milanese G, Opitz I, Weder W, Frauenfelder T.

Eur J Cardiothorac Surg. 2019 Mar 1;55(3):446-454. doi: 10.1093/ejcts/ezy277.


Preclinical, non-genetic models of lung adenocarcinoma: a comparative survey.

Janker F, Weder W, Jang JH, Jungraithmayr W.

Oncotarget. 2018 Jul 17;9(55):30527-30538. doi: 10.18632/oncotarget.25668. eCollection 2018 Jul 17.


Lung Transplantation with Controlled Donation after Circulatory Death Donors.

Inci I, Hillinger S, Schneiter D, Opitz I, Schuurmans M, Benden C, Weder W.

Ann Thorac Cardiovasc Surg. 2018 Dec 20;24(6):296-302. doi: 10.5761/atcs.oa.18-00098. Epub 2018 Jul 2.


Pleural mesothelioma: is the surgeon still there?

Opitz I, Weder W.

Ann Oncol. 2018 Aug 1;29(8):1710-1717. doi: 10.1093/annonc/mdy195. Review.


Early and late abdominal surgeries after lung transplantation: incidence and outcome.

Sulser P, Lehmann K, Schuurmans MM, Weder W, Inci I.

Interact Cardiovasc Thorac Surg. 2018 Nov 1;27(5):727-732. doi: 10.1093/icvts/ivy172.


Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice.

Gulati P, Rühl J, Kannan A, Pircher M, Schuberth P, Nytko KJ, Pruschy M, Sulser S, Haefner M, Jensen S, Soltermann A, Jungraithmayr W, Eisenring M, Winder T, Samaras P, Tabor A, Stenger R, Stupp R, Weder W, Renner C, Münz C, Petrausch U.

Clin Cancer Res. 2018 Aug 15;24(16):3981-3993. doi: 10.1158/1078-0432.CCR-17-1788. Epub 2018 May 10.


Pulmonary hypertension is not a risk factor for grade 3 primary graft dysfunction after lung transplantation.

Cottini SR, Brandi G, Pagnamenta A, Weder W, Schuepbach RA, Béchir M, Huber LC, Benden C.

Clin Transplant. 2018 May;32(5):e13251. doi: 10.1111/ctr.13251. Epub 2018 Apr 30.


Urokinase application for hemothorax in pulmonary mucormycosis.

Hodel L, Inci I, Schanz U, Vrugt B, Weder W, Hillinger S.

J Thorac Dis. 2018 Mar;10(3):E175-E178. doi: 10.21037/jtd.2018.03.01.



Weder W.

Pneumologie. 2018 Apr;72(4):321. doi: 10.1055/a-0586-6496. Epub 2018 Apr 11. German. No abstract available.


Lung volume reduction surgery in selected patients with emphysema and pulmonary hypertension.

Caviezel C, Aruldas C, Franzen D, Ulrich S, Inci I, Schneiter D, Weder W, Opitz I.

Eur J Cardiothorac Surg. 2018 Sep 1;54(3):565-571. doi: 10.1093/ejcts/ezy092.


Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.

George J, Walter V, Peifer M, Alexandrov LB, Seidel D, Leenders F, Maas L, Müller C, Dahmen I, Delhomme TM, Ardin M, Leblay N, Byrnes G, Sun R, De Reynies A, McLeer-Florin A, Bosco G, Malchers F, Menon R, Altmüller J, Becker C, Nürnberg P, Achter V, Lang U, Schneider PM, Bogus M, Soloway MG, Wilkerson MD, Cun Y, McKay JD, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Lemaitre N, Soltermann A, Weder W, Tischler V, Brustugun OT, Lund-Iversen M, Helland Å, Solberg S, Ansén S, Wright G, Solomon B, Roz L, Pastorino U, Petersen I, Clement JH, Sänger J, Wolf J, Vingron M, Zander T, Perner S, Travis WD, Haas SA, Olivier M, Foll M, Büttner R, Hayes DN, Brambilla E, Fernandez-Cuesta L, Thomas RK.

Nat Commun. 2018 Mar 13;9(1):1048. doi: 10.1038/s41467-018-03099-x.


Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression.

Oehl K, Kresoja-Rakic J, Opitz I, Vrugt B, Weder W, Stahel R, Wild P, Felley-Bosco E.

Front Oncol. 2018 Feb 23;8:40. doi: 10.3389/fonc.2018.00040. eCollection 2018.


Influence of inter-observer delineation variability on radiomics stability in different tumor sites.

Pavic M, Bogowicz M, Würms X, Glatz S, Finazzi T, Riesterer O, Roesch J, Rudofsky L, Friess M, Veit-Haibach P, Huellner M, Opitz I, Weder W, Frauenfelder T, Guckenberger M, Tanadini-Lang S.

Acta Oncol. 2018 Aug;57(8):1070-1074. doi: 10.1080/0284186X.2018.1445283. Epub 2018 Mar 7.


Computationally-Guided Development of a Stromal Inflammation Histologic Biomarker in Lung Squamous Cell Carcinoma.

Xia D, Casanova R, Machiraju D, McKee TD, Weder W, Beck AH, Soltermann A.

Sci Rep. 2018 Mar 2;8(1):3941. doi: 10.1038/s41598-018-22254-4.


A strategy to analyse activity-based profiling of tyrosine kinase substrates in OCT-embedded lung cancer tissue.

Arni S, de Wijn R, Garcia-Villegas R, Bitanihirwe BKY, Caviezel C, Weder W, Hillinger S.

Anal Biochem. 2018 Apr 15;547:77-83. doi: 10.1016/j.ab.2018.02.001. Epub 2018 Feb 22.


What's happening next.

Rocco G, Weder W.

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1781-1782. doi: 10.1016/j.jtcvs.2017.12.060. Epub 2017 Dec 23. No abstract available.


Extracorporeal photopheresis as second-line treatment therapy in life-threatening primary graft dysfunction following lung transplantation.

Robinson CA, Inci I, Naegeli M, Murer C, Schuurmans MM, Urosevic-Maiwald M, Schüpbach R, Weder W, Benden C.

Pediatr Transplant. 2018 May;22(3):e13145. doi: 10.1111/petr.13145. Epub 2018 Jan 29.


[Lung Volume Reduction Surgery].

Caviezel C, Franzen D, Weder W.

Pneumologie. 2018 Jan;72(1):64-78. doi: 10.1055/s-0043-103363. Epub 2018 Jan 16. Review. German.


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