Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 86

1.

Spatial memory deficits in mice induced by chemotherapeutic agents are prevented by acetylcholinesterase inhibitors.

Philpot RM, Ficken M, Johns BE, Engberg ME, Wecker L.

Cancer Chemother Pharmacol. 2019 Sep;84(3):579-589. doi: 10.1007/s00280-019-03881-8. Epub 2019 Jul 13.

PMID:
31302713
2.

Longitudinal gait and balance decline in Friedreich's Ataxia: A pilot study.

Zesiewicz TA, Stephenson JB, Kim SH, Sullivan KL, Jahan I, Huang Y, Salemi JL, Wecker L, Shaw JD, Gooch CL.

Gait Posture. 2017 Jun;55:25-30. doi: 10.1016/j.gaitpost.2017.03.019. Epub 2017 Mar 30.

PMID:
28411441
3.

3-Acetylpyridine neurotoxicity in mice.

Wecker L, Marrero-Rosado B, Engberg ME, Johns BE, Philpot RM.

Neurotoxicology. 2017 Jan;58:143-152. doi: 10.1016/j.neuro.2016.11.010. Epub 2016 Dec 13.

4.

Doxorubicin and cyclophosphamide lead to long-lasting impairment of spatial memory in female, but not male mice.

Philpot RM, Ficken M, Wecker L.

Behav Brain Res. 2016 Jul 1;307:165-75. doi: 10.1016/j.bbr.2016.04.017. Epub 2016 Apr 12.

PMID:
27083301
5.

Obstacles and Opportunities for Cholinergic Drug Development in the Treatment of Cognitive Disorders.

Schroeder RA, Wecker L, Philpot RM.

Curr Pharm Des. 2016;22(14):1981-5. Review.

PMID:
26818870
6.

Regulation of Gait and Balance: The Underappreciated Role of Neuronal Nicotinic Receptor Agonists.

Young MF, Wecker L.

Curr Pharm Des. 2016;22(14):1998-2003. Review.

PMID:
26818868
7.

Where are the women?

Wecker L.

Acad Med. 2015 Aug;90(8):1003. doi: 10.1097/ACM.0000000000000781. No abstract available.

PMID:
26218359
8.

Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments.

Lambert CS, Philpot RM, Engberg ME, Johns BE, Wecker L.

Behav Brain Res. 2015 Sep 15;291:342-350. doi: 10.1016/j.bbr.2015.05.056. Epub 2015 Jun 3.

9.

Gait and balance in adults with Friedreich's ataxia.

Stephenson J, Zesiewicz T, Gooch C, Wecker L, Sullivan K, Jahan I, Kim SH.

Gait Posture. 2015 Feb;41(2):603-7. doi: 10.1016/j.gaitpost.2015.01.002. Epub 2015 Jan 8.

PMID:
25662043
10.

Gait analysis and the cumulative gait index (CGI): Translational tools to assess impairments exhibited by rats with olivocerebellar ataxia.

Lambert CS, Philpot RM, Engberg ME, Johns BE, Kim SH, Wecker L.

Behav Brain Res. 2014 Nov 1;274:334-43. doi: 10.1016/j.bbr.2014.08.004. Epub 2014 Aug 10.

11.

Postpartum depression in rats: differences in swim test immobility, sucrose preference and nurturing behaviors.

Fernandez JW, Grizzell JA, Philpot RM, Wecker L.

Behav Brain Res. 2014 Oct 1;272:75-82. doi: 10.1016/j.bbr.2014.06.041. Epub 2014 Jun 29.

PMID:
24983658
12.
13.

Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia.

Wecker L, Engberg ME, Philpot RM, Lambert CS, Kang CW, Antilla JC, Bickford PC, Hudson CE, Zesiewicz TA, Rowell PP.

Neuropharmacology. 2013 Oct;73:75-86. doi: 10.1016/j.neuropharm.2013.05.016. Epub 2013 May 24.

14.

The role of estrogen receptor β and nicotinic cholinergic receptors in postpartum depression.

Fernandez JW, Grizzell JA, Wecker L.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:199-206. doi: 10.1016/j.pnpbp.2012.10.002. Epub 2012 Oct 9. Review.

PMID:
23063492
15.

A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3.

Zesiewicz TA, Greenstein PE, Sullivan KL, Wecker L, Miller A, Jahan I, Chen R, Perlman SL.

Neurology. 2012 Feb 21;78(8):545-50. doi: 10.1212/WNL.0b013e318247cc7a. Epub 2012 Feb 8. Erratum in: Neurology. 2012 Jul 31;79(5):488.

PMID:
22323747
16.

Effects of nicotine exposure on locomotor activity and pCREB levels in the ventral striatum of adolescent rats.

Philpot RM, Engberg ME, Wecker L.

Behav Brain Res. 2012 Apr 21;230(1):62-8. doi: 10.1016/j.bbr.2012.01.036. Epub 2012 Jan 24.

PMID:
22301350
17.

Nicotine-induced up regulation of α4β2 neuronal nicotinic receptors is mediated by the protein kinase C-dependent phosphorylation of α4 subunits.

Wecker L, Pollock VV, Pacheco MA, Pastoor T.

Neuroscience. 2010 Nov 24;171(1):12-22. doi: 10.1016/j.neuroscience.2010.09.005. Epub 2010 Sep 17.

18.

Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

Papke RL, Wecker L, Stitzel JA.

J Pharmacol Exp Ther. 2010 May;333(2):501-18. doi: 10.1124/jpet.109.164566. Epub 2010 Jan 25.

19.

Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi.

Philpot RM, Wecker L, Kirstein CL.

Int J Dev Neurosci. 2009 Dec;27(8):805-15. doi: 10.1016/j.ijdevneu.2009.08.009. Epub 2009 Aug 25.

PMID:
19712739
20.

Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.

Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST.

Arch Neurol. 2009 May;66(5):646-51. doi: 10.1001/archneurol.2009.46.

21.

Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate alpha4beta2 nicotinic receptor subunits at distinct stages of receptor formation and maturation.

Pollock VV, Pastoor T, Katnik C, Cuevas J, Wecker L.

Neuroscience. 2009 Feb 18;158(4):1311-25. doi: 10.1016/j.neuroscience.2008.11.032. Epub 2008 Nov 27.

22.

Dependence of adolescent novelty-seeking behavior on response phenotype and effects of apparatus scaling.

Philpot RM, Wecker L.

Behav Neurosci. 2008 Aug;122(4):861-75. doi: 10.1037/0735-7044.122.4.861.

PMID:
18729640
24.

The controversy concerning plasma homocysteine in Parkinson disease patients treated with levodopa alone or with entacapone: effects of vitamin status.

Zesiewicz TA, Wecker L, Sullivan KL, Merlin LR, Hauser RA.

Clin Neuropharmacol. 2006 May-Jun;29(3):106-11. Review.

PMID:
16772808
25.

The alpha7 nicotinic acetylcholine receptor subunit exists in two isoforms that contribute to functional ligand-gated ion channels.

Severance EG, Zhang H, Cruz Y, Pakhlevaniants S, Hadley SH, Amin J, Wecker L, Reed C, Cuevas J.

Mol Pharmacol. 2004 Sep;66(3):420-9.

PMID:
15322233
26.

Developmental differences in nicotine place conditioning.

Torrella TA, Badanich KA, Philpot RM, Kirstein CL, Wecker L.

Ann N Y Acad Sci. 2004 Jun;1021:399-403.

PMID:
15251917
27.

Transdermal selegiline: targeted effects on monoamine oxidases in the brain.

Wecker L, James S, Copeland N, Pacheco MA.

Biol Psychiatry. 2003 Nov 15;54(10):1099-104.

PMID:
14625153
28.
31.

Characterization of human alpha4beta2 neuronal nicotinic receptors stably expressed in SH-EP1 cells.

Pacheco MA, Pastoor TE, Lukas RJ, Wecker L.

Neurochem Res. 2001 Jun;26(6):683-93.

PMID:
11519728
33.

Differential effects of nicotine and aging on splenocyte proliferation and the production of Th1- versus Th2-type cytokines.

Hallquist N, Hakki A, Wecker L, Friedman H, Pross S.

Proc Soc Exp Biol Med. 2000 Jul;224(3):141-6.

PMID:
10865228
34.

Neonatal cytomegalovirus exposure decreases prepulse inhibition in adult rats: implications for schizophrenia.

Rothschild DM, O'Grady M, Wecker L.

J Neurosci Res. 1999 Aug 15;57(4):429-34.

PMID:
10440892
35.

Oral versus transdermal selegiline: antidepressant-like activity in rats.

Gordon MN, Muller CD, Sherman KA, Morgan DG, Azzaro AJ, Wecker L.

Pharmacol Biochem Behav. 1999 Jul;63(3):501-6.

PMID:
10418793
37.

Comparison of nicotinic receptor binding and biotransformation of coniine in the rat and chick.

Forsyth CS, Speth RC, Wecker L, Galey FD, Frank AA.

Toxicol Lett. 1996 Dec 31;89(3):175-83.

PMID:
9001585
38.

Effects of phenobarbital and interleukin-6 on cytochrome P4502B1 and 2B2 in cultured rat hepatocytes.

Clark MA, Williams JF, Gottschall PE, Wecker L.

Biochem Pharmacol. 1996 Mar 8;51(5):701-6.

PMID:
8615908
39.
40.
41.
42.

Differential effect of chronic nicotine administration on brain cytochrome P4501A1/2 and P4502E1.

Anandatheerthavarada HK, Williams JF, Wecker L.

Biochem Biophys Res Commun. 1993 Jul 15;194(1):312-8.

PMID:
8333846
43.

The chronic administration of nicotine induces cytochrome P450 in rat brain.

Anandatheerthavarada HK, Williams JF, Wecker L.

J Neurochem. 1993 May;60(5):1941-4.

PMID:
8473908
45.

Dietary choline supplementation increases the density of nicotine binding sites in rat brain.

Coutcher JB, Cawley G, Wecker L.

J Pharmacol Exp Ther. 1992 Sep;262(3):1128-32.

PMID:
1326624
47.

The aging population. A critical issue in medicine for the 21st century.

Wecker L, Krzanowski JJ, Polson J, Fitzpatrick D, Coffey R, Williams J, Hackney J.

J Fla Med Assoc. 1991 Oct;78(10):643-5. Review.

PMID:
1753224
48.
49.

Effects of streptozotocin-induced diabetes on acetylcholine metabolism in rat brain.

Welsh B, Wecker L.

Neurochem Res. 1991 Apr;16(4):453-60.

PMID:
1833657
50.

Muscarinic receptor blockade increases basal acetylcholine release from striatal slices.

Dolezal V, Wecker L.

J Pharmacol Exp Ther. 1990 Feb;252(2):739-43.

PMID:
2313598

Supplemental Content

Loading ...
Support Center