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Items: 1 to 50 of 154

1.

Adherence to Adding Inhaled Corticosteroids to Rescue Therapy in a Pragmatic Trial with Adults with Asthma- a Pilot Study.

Cardet JC, Busse PJ, Carroll JK, Casale TB, Coyne-Beasley T, Dixon-Williams S, Fagan M, Forth VE, Fuhlbrigge AL, Hernandez ML, Kaelber D, Kaplan B, Lorenzi M, Madison S, Maher NE, Majewski K, Manning B, McKee MD, Nazario S, Pace WD, Pencina MJ, Rand CS, Rodriguez-Louis J, She L, Shields J, Teng JE, Wechsler ME, Wisnivesky JP, Yawn BP, Israel E.

Ann Allergy Asthma Immunol. 2020 Jan 7. pii: S1081-1206(20)30002-8. doi: 10.1016/j.anai.2019.12.027. [Epub ahead of print]

PMID:
31923550
2.

Letter from the USA.

Wechsler ME.

Respirology. 2020 Feb;25(2):221-222. doi: 10.1111/resp.13757. Epub 2019 Dec 17. No abstract available.

3.

Characterization of Severe Asthma Worldwide: Data From the International Severe Asthma Registry.

Wang E, Wechsler ME, Tran TN, Heaney LG, Jones RC, Menzies-Gow AN, Busby J, Jackson DJ, Pfeffer PE, Rhee CK, Cho YS, Canonica GW, Heffler E, Gibson PG, Hew M, Peters M, Harvey ES, Alacqua M, Zangrilli J, Bulathsinhala L, Carter VA, Chaudhry I, Eleangovan N, Hosseini N, Murray RB, Price DB.

Chest. 2019 Nov 27. pii: S0012-3692(19)34295-3. doi: 10.1016/j.chest.2019.10.053. [Epub ahead of print]

4.

Improving end-of-rotation transitions of care among ICU patients.

Denson JL, Knoeckel J, Kjerengtroen S, Johnson R, McNair B, Thornton O, Douglas IS, Wechsler ME, Burke RE.

BMJ Qual Saf. 2019 Nov 4. pii: bmjqs-2019-009867. doi: 10.1136/bmjqs-2019-009867. [Epub ahead of print]

PMID:
31685581
5.

Developing a Multidisciplinary Approach for Engineering Stem Cell Organoids.

Wechsler ME, Shevchuk M, Peppas NA.

Ann Biomed Eng. 2019 Oct 28. doi: 10.1007/s10439-019-02391-1. [Epub ahead of print]

PMID:
31659603
6.

Trends in Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis-Related Mortality in the United States, 1999 to 2017.

Steinberg AW, Wechsler ME, Fernández Pérez ER.

Ann Intern Med. 2019 Oct 8. doi: 10.7326/M19-1564. [Epub ahead of print] No abstract available.

PMID:
31590187
7.

Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.

Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF Jr, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E; NHLBI AsthmaNet.

N Engl J Med. 2019 Sep 26;381(13):1227-1239. doi: 10.1056/NEJMoa1905560.

PMID:
31553835
8.

Exacerbation-prone asthma in the context of race and ancestry in Asthma Clinical Research Network trials.

Grossman NL, Ortega VE, King TS, Bleecker ER, Ampleford EA, Bacharier LB, Cabana MD, Cardet JC, Carr TF, Castro M, Denlinger LC, Denson JL, Fandino N, Fitzpatrick AM, Hawkins GA, Holguin F, Krishnan JA, Lazarus SC, Nyenhuis SM, Phipatanakul W, Ramratnam SK, Wenzel S, Peters SP, Meyers DA, Wechsler ME, Israel E.

J Allergy Clin Immunol. 2019 Dec;144(6):1524-1533. doi: 10.1016/j.jaci.2019.08.033. Epub 2019 Sep 11.

PMID:
31520679
9.

Reply.

Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E; AsthmaNet Investigators.

J Allergy Clin Immunol. 2019 Sep;144(3):873-874. doi: 10.1016/j.jaci.2019.05.029. Epub 2019 Jul 9. No abstract available.

PMID:
31300279
10.

Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.

Lazarus SC, Krishnan JA, King TS, Lang JE, Blake KV, Covar R, Lugogo N, Wenzel S, Chinchilli VM, Mauger DT, Dyer AM, Boushey HA, Fahy JV, Woodruff PG, Bacharier LB, Cabana MD, Cardet JC, Castro M, Chmiel J, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Hastie A, Holguin F, Israel E, Jackson D, Kraft M, LaForce C, Lemanske RF Jr, Martinez FD, Moore W, Morgan WJ, Moy JN, Myers R, Peters SP, Phipatanakul W, Pongracic JA, Que L, Ross K, Smith L, Szefler SJ, Wechsler ME, Sorkness CA; National Heart, Lung, and Blood Institute AsthmaNet.

N Engl J Med. 2019 May 23;380(21):2009-2019. doi: 10.1056/NEJMoa1814917. Epub 2019 May 19.

11.

Reply.

Wechsler ME, Pouliquen I, Steinfeld J, Bradford ES; MIRRA study team.

J Allergy Clin Immunol. 2019 Aug;144(2):622. doi: 10.1016/j.jaci.2019.03.031. Epub 2019 May 2. No abstract available.

PMID:
31056189
12.

Engineered microscale hydrogels for drug delivery, cell therapy, and sequencing.

Wechsler ME, Stephenson RE, Murphy AC, Oldenkamp HF, Singh A, Peppas NA.

Biomed Microdevices. 2019 Mar 23;21(2):31. doi: 10.1007/s10544-019-0358-0. Review.

13.

Loss of bronchoprotection with ICS plus LABA treatment, β-receptor dynamics, and the effect of alendronate.

Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E; AsthmaNet Investigators.

J Allergy Clin Immunol. 2019 Aug;144(2):416-425.e7. doi: 10.1016/j.jaci.2019.01.049. Epub 2019 Mar 11.

14.

Asthma over the Adult Life Course: Gender and Hormonal Influences.

Zein JG, Denson JL, Wechsler ME.

Clin Chest Med. 2019 Mar;40(1):149-161. doi: 10.1016/j.ccm.2018.10.009. Epub 2018 Dec 20. Review.

PMID:
30691709
15.

Genetic associations of the response to inhaled corticosteroids in asthma: a systematic review.

Keskin O, Farzan N, Birben E, Akel H, Karaaslan C, Maitland-van der Zee AH, Wechsler ME, Vijverberg SJ, Kalayci O.

Clin Transl Allergy. 2019 Jan 9;9:2. doi: 10.1186/s13601-018-0239-2. eCollection 2019. Review.

16.

Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era.

Sorkness CA, King TS, Dyer AM, Chinchilli VM, Mauger DT, Krishnan JA, Blake K, Castro M, Covar R, Israel E, Kraft M, Lang JE, Lugogo N, Peters SP, Wechsler ME, Wenzel SE, Lazarus SC; National Heart Lung and Blood Institute's “AsthmaNet”.

Contemp Clin Trials. 2019 Feb;77:98-103. doi: 10.1016/j.cct.2018.12.012. Epub 2018 Dec 27.

PMID:
30593883
17.

Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis.

Steinfeld J, Bradford ES, Brown J, Mallett S, Yancey SW, Akuthota P, Cid MC, Gleich GJ, Jayne D, Khoury P, Langford CA, Merkel PA, Moosig F, Specks U, Weller PF, Wechsler ME.

J Allergy Clin Immunol. 2019 Jun;143(6):2170-2177. doi: 10.1016/j.jaci.2018.11.041. Epub 2018 Dec 19.

PMID:
30578883
18.

Clinical Issues in Severe Asthma: Debates and Discussions About Personalizing Patient Management.

Panettieri RA Jr, Wechsler ME, Wenzel SE.

Chest. 2018 Dec;154(6):1459-1460. doi: 10.1016/j.chest.2018.09.002.

PMID:
30526975
19.

Confronting the Challenges of Severe Asthma.

Gelfand EW, Wechsler ME.

J Fam Pract. 2018 Oct;67(10 Suppl):S19-S26. No abstract available.

PMID:
30423007
20.

The asthma Symptom Free Days Questionnaire: how reliable are patient responses?

Yawn BP, Israel E, Wechsler ME, Pace W, Madison S, Manning B, Doros G, Fuhlbrigge A.

J Asthma. 2019 Nov;56(11):1222-1230. doi: 10.1080/02770903.2018.1531990. Epub 2018 Oct 26.

PMID:
30365368
21.

Predictors of inhaled corticosteroid taper failure in adults with asthma.

Cardet JC, Codispoti CD, King TS, Bacharier L, Carr T, Castro M, Chinchilli V, Dunn R, Holquing F, Engle L, Nelson K, Ortega VE, Peters M, Ramratnam S, Krishnan JA, Wechsler ME, Israel E; National Heart, Lung, and Blood Institute Asthmanet.

J Allergy Clin Immunol Pract. 2019 Apr;7(4):1335-1337.e3. doi: 10.1016/j.jaip.2018.05.039. Epub 2018 Sep 19. No abstract available.

22.

Label-Free Detection of Tear Biomarkers Using Hydrogel-Coated Gold Nanoshells in a Localized Surface Plasmon Resonance-Based Biosensor.

Culver HR, Wechsler ME, Peppas NA.

ACS Nano. 2018 Sep 25;12(9):9342-9354. doi: 10.1021/acsnano.8b04348. Epub 2018 Sep 14.

23.

Baseline patient factors impact on the clinical efficacy of benralizumab for severe asthma.

Bleecker ER, Wechsler ME, FitzGerald JM, Menzies-Gow A, Wu Y, Hirsch I, Goldman M, Newbold P, Zangrilli JG.

Eur Respir J. 2018 Oct 18;52(4). pii: 1800936. doi: 10.1183/13993003.00936-2018. Print 2018 Oct.

24.

Selecting the right biologic for your patients with severe asthma.

Manka LA, Wechsler ME.

Ann Allergy Asthma Immunol. 2018 Oct;121(4):406-413. doi: 10.1016/j.anai.2018.07.033. Epub 2018 Jul 27. Review.

PMID:
30056149
25.

Susceptibility to exacerbations in Black adults with asthma.

Grossman NL, Doros GD, Fandino N, Fuhlbrigge AL, Pace WD, Wechsler ME, Yawn BP, Israel E.

J Asthma. 2019 Jul;56(7):704-710. doi: 10.1080/02770903.2018.1486855. Epub 2018 Oct 4.

PMID:
29969928
26.

Association of free vitamin D3 concentrations and asthma treatment failures in the VIDA Trial.

Lima JJ, Castro M, King TS, Lang JE, Ortega VE, Peters SP, Denlinger LC, Israel E, Sorkness CA, Wechsler ME, Wenzel SE, Smith LJ.

Ann Allergy Asthma Immunol. 2018 Oct;121(4):444-450.e1. doi: 10.1016/j.anai.2018.06.001. Epub 2018 Jun 14.

27.

Bacterial biogeography of adult airways in atopic asthma.

Durack J, Huang YJ, Nariya S, Christian LS, Ansel KM, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, King TS, White SR, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Peters SP, Smith LJ, Wechsler ME, Lynch SV, Boushey HA; National Heart, Lung and Blood Institute’s “AsthmaNet”.

Microbiome. 2018 Jun 9;6(1):104. doi: 10.1186/s40168-018-0487-3.

28.

Current and Emerging Biologic Therapies for Asthma and COPD.

Wechsler ME.

Respir Care. 2018 Jun;63(6):699-707. doi: 10.4187/respcare.06322. Review.

29.

Identification of remission in adult-onset asthma.

Busse P, Wechsler ME.

Lancet Respir Med. 2018 Jun;6(6):417-418. doi: 10.1016/S2213-2600(18)30175-9. Epub 2018 Apr 23. No abstract available.

PMID:
29699818
30.

Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).

Khoury P, Akuthota P, Ackerman SJ, Arron JR, Bochner BS, Collins MH, Kahn JE, Fulkerson PC, Gleich GJ, Gopal-Srivastava R, Jacobsen EA, Leiferman KM, Francesca LS, Mathur SK, Minnicozzi M, Prussin C, Rothenberg ME, Roufosse F, Sable K, Simon D, Simon HU, Spencer LA, Steinfeld J, Wardlaw AJ, Wechsler ME, Weller PF, Klion AD.

J Leukoc Biol. 2018 Jul;104(1):69-83. doi: 10.1002/JLB.5MR0118-028R. Epub 2018 Apr 19. Review.

31.

New biologics for allergic diseases.

Manka LA, Wechsler ME.

Expert Rev Clin Immunol. 2018 Apr;14(4):285-296. doi: 10.1080/1744666X.2018.1459188. Epub 2018 Apr 10. Review.

PMID:
29611440
32.

Mepolizumab Treatment of Pediatric Eosinophilic Granulomatosis With Polyangiitis.

Joseph MX, Jenkins LE, Wechsler ME, Davis LS.

JAMA Dermatol. 2018 Apr 1;154(4):486-487. doi: 10.1001/jamadermatol.2017.5888. No abstract available.

PMID:
29466544
33.

Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease.

Tashkin DP, Wechsler ME.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 17;13:335-349. doi: 10.2147/COPD.S152291. eCollection 2018. Review.

34.

Care pathways for the selection of a biologic in severe asthma.

Bousquet J, Brusselle G, Buhl R, Busse WW, Cruz AA, Djukanovic R, Domingo C, Hanania NA, Humbert M, Menzies Gow A, Phipatanakul W, Wahn U, Wechsler ME.

Eur Respir J. 2017 Dec 7;50(6). pii: 1701782. doi: 10.1183/13993003.01782-2017. Print 2017 Dec. No abstract available.

35.

Severe Asthma and the Primary Care Provider: Identifying Patients and Coordinating Multidisciplinary Care.

Yawn BP, Wechsler ME.

Am J Med. 2017 Dec;130(12):1479. doi: 10.1016/j.amjmed.2017.10.001. Epub 2017 Oct 3.

PMID:
28986071
36.

Vision for Functionally Decorated and Molecularly Imprinted Polymers in Regenerative Engineering.

Clegg JR, Wechsler ME, Peppas NA.

Regen Eng Transl Med. 2017 Sep;3(3):166-175. doi: 10.1007/s40883-017-0028-9. Epub 2017 Mar 20.

37.

Novel Treatments for Airway Disease.

Wechsler ME, Akuthota P, Khoury P.

N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. No abstract available.

PMID:
28812971
38.

Novel Treatments for Airway Disease.

Wechsler ME, Akuthota P, Khoury P.

N Engl J Med. 2017 Aug 10;377(6):597-8. doi: 10.1056/NEJMc1708004. No abstract available.

PMID:
28792869
39.

Concern of underdiagnosing asthma-COPD overlap syndrome if age limit of 40 years for asthma is used.

Sin DD, Leung JM, Wechsler ME.

Eur Respir J. 2017 Aug 3;50(2). pii: 1701120. doi: 10.1183/13993003.01120-2017. Print 2017 Aug. No abstract available.

40.

Charged poly(N-isopropylacrylamide) nanogels for use as differential protein receptors in a turbidimetric sensor array.

Culver HR, Sharma I, Wechsler ME, Anslyn EV, Peppas NA.

Analyst. 2017 Aug 21;142(17):3183-3193. doi: 10.1039/c7an00787f.

41.

Asthma in the elderly and late-onset adult asthma.

Dunn RM, Busse PJ, Wechsler ME.

Allergy. 2018 Feb;73(2):284-294. doi: 10.1111/all.13258. Epub 2017 Sep 7. Review.

PMID:
28722758
42.

Income is an independent risk factor for worse asthma outcomes.

Cardet JC, Louisias M, King TS, Castro M, Codispoti CD, Dunn R, Engle L, Giles BL, Holguin F, Lima JJ, Long D, Lugogo N, Nyenhuis S, Ortega VE, Ramratnam S, Wechsler ME, Israel E, Phipatanakul W; Vitamin D Add-On Therapy Enhances Corticosteroid Disparities Working Group members on behalf of the AsthmaNet investigators.

J Allergy Clin Immunol. 2018 Feb;141(2):754-760.e3. doi: 10.1016/j.jaci.2017.04.036. Epub 2017 May 20.

43.

KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma.

Cahill KN, Katz HR, Cui J, Lai J, Kazani S, Crosby-Thompson A, Garofalo D, Castro M, Jarjour N, DiMango E, Erzurum S, Trevor JL, Shenoy K, Chinchilli VM, Wechsler ME, Laidlaw TM, Boyce JA, Israel E.

N Engl J Med. 2017 May 18;376(20):1911-1920. doi: 10.1056/NEJMoa1613125.

44.

Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.

Wechsler ME, Akuthota P, Jayne D, Khoury P, Klion A, Langford CA, Merkel PA, Moosig F, Specks U, Cid MC, Luqmani R, Brown J, Mallett S, Philipson R, Yancey SW, Steinfeld J, Weller PF, Gleich GJ; EGPA Mepolizumab Study Team.

N Engl J Med. 2017 May 18;376(20):1921-1932. doi: 10.1056/NEJMoa1702079.

45.

Changing Paradigms in the Treatment of Severe Asthma: The Role of Biologic Therapies.

Katial RK, Bensch GW, Busse WW, Chipps BE, Denson JL, Gerber AN, Jacobs JS, Kraft M, Martin RJ, Nair P, Wechsler ME.

J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2S):S1-S14. doi: 10.1016/j.jaip.2016.11.029. Epub 2017 Jan 29. Review.

PMID:
28143691
46.

Race is associated with differences in airway inflammation in patients with asthma.

Nyenhuis SM, Krishnan JA, Berry A, Calhoun WJ, Chinchilli VM, Engle L, Grossman N, Holguin F, Israel E, Kittles RA, Kraft M, Lazarus SC, Lehman EB, Mauger DT, Moy JN, Peters SP, Phipatanakul W, Smith LJ, Sumino K, Szefler SJ, Wechsler ME, Wenzel S, White SR, Ackerman SJ.

J Allergy Clin Immunol. 2017 Jul;140(1):257-265.e11. doi: 10.1016/j.jaci.2016.10.024. Epub 2017 Jan 6.

47.

Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.

Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler ME, Wenzel SE, Boushey HA, Huang YJ; National Heart, Lung and Blood Institute's “AsthmaNet”.

J Allergy Clin Immunol. 2017 Jul;140(1):63-75. doi: 10.1016/j.jaci.2016.08.055. Epub 2016 Nov 10.

48.

Respiratory manifestations of eosinophilic granulomatosis with polyangiitis (Churg-Strauss).

Cottin V, Bel E, Bottero P, Dalhoff K, Humbert M, Lazor R, Sinico RA, Sivasothy P, Wechsler ME, Groh M, Marchand-Adam S, Khouatra C, Wallaert B, Taillé C, Delaval P, Cadranel J, Bonniaud P, Prévot G, Hirschi S, Gondouin A, Dunogué B, Chatté G, Briault A, Jayne D, Guillevin L, Cordier JF; the Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires (GERM“O”P).

Eur Respir J. 2016 Nov;48(5):1429-1441. doi: 10.1183/13993003.00097-2016. Epub 2016 Sep 1.

49.

Revisiting the systemic vasculitis in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): A study of 157 patients by the Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires and the European Respiratory Society Taskforce on eosinophilic granulomatosis with polyangiitis (Churg-Strauss).

Cottin V, Bel E, Bottero P, Dalhoff K, Humbert M, Lazor R, Sinico RA, Sivasothy P, Wechsler ME, Groh M, Marchand-Adam S, Khouatra C, Wallaert B, Taillé C, Delaval P, Cadranel J, Bonniaud P, Prévot G, Hirschi S, Gondouin A, Dunogué B, Chatté G, Briault C, Pagnoux C, Jayne D, Guillevin L, Cordier JF; Groupe d’Etudes et de Recherche sur les Maladies Orphelines Pulmonaires (GERM“O”P).

Autoimmun Rev. 2017 Jan;16(1):1-9. doi: 10.1016/j.autrev.2016.09.018. Epub 2016 Sep 23.

PMID:
27671089
50.

Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.

Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W; NIH/NHLBI AsthmaNet.

N Engl J Med. 2016 Aug 18;375(7):619-30. doi: 10.1056/NEJMoa1515990.

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