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Items: 6


Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.

Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, Donoho GP, Van Horn RD, Barnard DS, Dempsey JA, Beckmann RP, Marshall MS, Chio LC, Qian Y, Webster YW, Aggarwal A, Chu S, Bhattachar S, Stancato LF, Dowless MS, Iversen PW, Manro JR, Walgren JL, Halstead BW, Dieter MZ, Martinez R, Bhagwat SV, Kreklau EL, Lallena MJ, Ye XS, Patel BKR, Reinhard C, Plowman GD, Barda DA, Henry JR, Buchanan SG, Campbell RM.

Mol Cancer Ther. 2019 Dec;18(12):2207-2219. doi: 10.1158/1535-7163.MCT-18-0529. Epub 2019 Sep 17.


A Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results.

Sutherland JJ, Stevens JL, Johnson K, Elango N, Webster YW, Mills BJ, Robertson DH.

Toxicol Sci. 2019 Aug 1;170(2):296-309. doi: 10.1093/toxsci/kfz101.


Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with BRAF or KRAS Mutations.

Yao YM, Donoho GP, Iversen PW, Zhang Y, Van Horn RD, Forest A, Novosiadly RD, Webster YW, Ebert P, Bray S, Ting JC, Aggarwal A, Henry JR, Tiu RV, Plowman GD, Peng SB.

Clin Cancer Res. 2017 Sep 15;23(18):5547-5560. doi: 10.1158/1078-0432.CCR-16-3250. Epub 2017 Jun 13.


Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity.

Sutherland JJ, Webster YW, Willy JA, Searfoss GH, Goldstein KM, Irizarry AR, Hall DG, Stevens JL.

Pharmacogenomics J. 2018 May 22;18(3):377-390. doi: 10.1038/tpj.2017.17. Epub 2017 Apr 25.


Leveraging health social networking communities in translational research.

Webster YW, Dow ER, Koehler J, Gudivada RC, Palakal MJ.

J Biomed Inform. 2011 Aug;44(4):536-44. doi: 10.1016/j.jbi.2011.01.010. Epub 2011 Feb 1.


Structure-guided expansion of kinase fragment libraries driven by support vector machine models.

Erickson JA, Mader MM, Watson IA, Webster YW, Higgs RE, Bell MA, Vieth M.

Biochim Biophys Acta. 2010 Mar;1804(3):642-52. doi: 10.1016/j.bbapap.2009.12.002. Epub 2009 Dec 11.


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