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OpEn-Tag: a customizable optogenetic toolbox to dissect subcellular signaling.

Mühlhäuser WWD, Weber W, Radziwill G.

ACS Synth Biol. 2019 Jun 11. doi: 10.1021/acssynbio.9b00059. [Epub ahead of print]


89Zr-immuno-PET: towards a non-invasive clinical tool to measure target engagement of therapeutic antibodies in-vivo.

Jauw Y, o'Donoghue J, Zijlstra J, Hoekstra O, Menke-van der Houven van Oordt CW, Morschhauser F, Carrasquillo J, Zweegman S, Pandit-Taskar N, Lammertsma A, van Dongen G, Boellaard R, Weber W, Huisman M.

J Nucl Med. 2019 May 30. pii: jnumed.118.224568. doi: 10.2967/jnumed.118.224568. [Epub ahead of print]


Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration.

Turner HC, Lee Y, Weber W, Melo D, Kowell A, Ghandhi SA, Amundson SA, Brenner DJ, Shuryak I.

BMC Mol Cell Biol. 2019 May 28;20(1):13. doi: 10.1186/s12860-019-0195-2.


Design of a Human Rhinovirus-14 3C Protease-Inducible Caspase-3.

Wagner HJ, Weber W.

Molecules. 2019 May 21;24(10). pii: E1945. doi: 10.3390/molecules24101945.


Clinical Validation of the BREAST-Q Breast-Conserving Therapy Module.

Stolpner I, Heil J, Feißt M, Karsten MM, Weber WP, Blohmer JU, Forster T, Golatta M, Schütz F, Sohn C, Hennigs A.

Ann Surg Oncol. 2019 May 21. doi: 10.1245/s10434-019-07456-y. [Epub ahead of print]


Americium Systemic Biokinetic Model for Rats.

Miller G, Klumpp JA, Poudel D, Weber W, Guilmette RA, Swanson J, Melo DR.

Radiat Res. 2019 May 20. doi: 10.1667/RR15256.1. [Epub ahead of print]


Integrating Early Rapid Post-Peptide Receptor Radionuclide Therapy Quality Assurance Scan into the Outpatient Setting.

Mahajan S, O'Donoghue J, Weber W, Bodei L.

J Nucl Med Radiat Ther. 2019;10(1). pii: 395. doi: 10.4172/2155-9619.1000395. Epub 2019 Feb 28.


Neurophysiological effects of multiple mood episodes in bipolar disorder.

Borgelt L, Strakowski SM, DelBello MP, Weber W, Eliassen JC, Komoroski RA, Chu WJ, Welge JA, Blom TJ, Rummelhoff E, Tallman M, Lee JH, Adler CM.

Bipolar Disord. 2019 Apr 26. doi: 10.1111/bdi.12782. [Epub ahead of print]


Cardiac Imaging Within Emergency CT Angiography for Acute Stroke Can Detect Atrial Clots.

Popkirov S, Schlegel U, Weber W, Kleffner I, Altenbernd J.

Front Neurol. 2019 Apr 10;10:349. doi: 10.3389/fneur.2019.00349. eCollection 2019.


Neuroimaging for Radiation Therapy of Brain Tumors.

Popp I, Weber WA, Combs SE, Yuh WTC, Grosu AL.

Top Magn Reson Imaging. 2019 Apr;28(2):63-71. doi: 10.1097/RMR.0000000000000198.


Prospective Study of the Radiolabeled GRPR Antagonist BAY86-7548 for Positron Emission Tomography/Computed Tomography Imaging of Newly Diagnosed Prostate Cancer.

Touijer KA, Michaud L, Alvarez HAV, Gopalan A, Kossatz S, Gonen M, Beattie B, Sandler I, Lyaschenko S, Eastham JA, Scardino PT, Hricak H, Weber WA.

Eur Urol Oncol. 2019 Mar;2(2):166-173. doi: 10.1016/j.euo.2018.08.011. Epub 2018 Sep 22.


The impact of depression on adherence to organized and opportunistic breast cancer screening.

Montagna G, Schneeberger AR, Rossi L, Reina H, Schwab FD, Schoetzau A, Eichholzer M, Pagani O, Weber WP, Kurzeder C, Güth U, Huber CG.

Eur J Cancer Prev. 2019 Apr 16. doi: 10.1097/CEJ.0000000000000520. [Epub ahead of print]


Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery in Recurrent Prostate Cancer.

Horn T, Krönke M, Rauscher I, Haller B, Robu S, Wester HJ, Schottelius M, van Leeuwen FWB, van der Poel HG, Heck M, Gschwend JE, Weber W, Eiber M, Maurer T.

Eur Urol. 2019 Apr 12. pii: S0302-2838(19)30278-7. doi: 10.1016/j.eururo.2019.03.045. [Epub ahead of print]


A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer.

Wagner J, Rapsomaniki MA, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, Rees M, Ramaswamy A, Muenst S, Soysal SD, Jacobs A, Windhager J, Silina K, van den Broek M, Dedes KJ, Rodríguez Martínez M, Weber WP, Bodenmiller B.

Cell. 2019 May 16;177(5):1330-1345.e18. doi: 10.1016/j.cell.2019.03.005. Epub 2019 Apr 11.


Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor.

Yousefi OS, Günther M, Hörner M, Chalupsky J, Wess M, Brandl SM, Smith RW, Fleck C, Kunkel T, Zurbriggen MD, Höfer T, Weber W, Schamel WW.

Elife. 2019 Apr 5;8. pii: e42475. doi: 10.7554/eLife.42475.


[On the Basis of the DeGIR/DGNR Register Nationwide Care for Acute Ischemic Stroke Patients in 2016 and 2017 Using Mechanical Thrombectomy by Radiologists and Neuroradiologists].

Berlis A, Morhard D, Weber W.

Rofo. 2019 Apr 4. doi: 10.1055/a-0857-6694. [Epub ahead of print] German. No abstract available.


Thermal stability and irradiation response of nanocrystalline CoCrCuFeNi high-entropy alloy.

Zhang Y, Tunes MA, Crespillo ML, Zhang F, Boldman WL, Rack PD, Jiang L, Xu C, Greaves G, Donnelly SE, Wang L, Weber WJ.

Nanotechnology. 2019 Jul 19;30(29):294004. doi: 10.1088/1361-6528/ab1605. Epub 2019 Apr 4.


Longitudinal proton spectroscopy study of the prefrontal cortex in youth at risk for bipolar disorder before and after their first mood episode.

Nery FG, Weber WA, Blom TJ, Welge J, Patino LR, Strawn JR, Chu WJ, Adler CM, Komoroski RA, Strakowski SM, DelBello MP.

Bipolar Disord. 2019 Mar 12. doi: 10.1111/bdi.12770. [Epub ahead of print]


Photolithographic Fabrication of Micro Apertures in Dry Film Polymer Sheets for Channel Recordings in Planar Lipid Bilayers.

Khoury ME, Winterstein T, Weber W, Stein V, Schlaak HF, Thiel G.

J Membr Biol. 2019 Jun;252(2-3):173-182. doi: 10.1007/s00232-019-00062-9. Epub 2019 Mar 12.


Light-Controlled Affinity Purification of Protein Complexes Exemplified by the Resting ZAP70 Interactome.

Hörner M, Eble J, Yousefi OS, Schwarz J, Warscheid B, Weber W, Schamel WWA.

Front Immunol. 2019 Feb 26;10:226. doi: 10.3389/fimmu.2019.00226. eCollection 2019.


qPSMA: a semi-automatic software for whole-body tumor burden assessment in prostate cancer using 68Ga-PSMA11 PET/CT.

Gafita A, Bieth M, Kroenke M, Tetteh G, Guenther E, Menze B, Weber WA, Eiber M.

J Nucl Med. 2019 Mar 8. pii: jnumed.118.224055. doi: 10.2967/jnumed.118.224055. [Epub ahead of print]


Biofunctionalized Materials Featuring Feedforward and Feedback Circuits Exemplified by the Detection of Botulinum Toxin A.

Wagner HJ, Kemmer S, Engesser R, Timmer J, Weber W.

Adv Sci (Weinh). 2018 Nov 28;6(4):1801320. doi: 10.1002/advs.201801320. eCollection 2019 Feb 20.


Neutrophils escort circulating tumour cells to enable cell cycle progression.

Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, Aceto N.

Nature. 2019 Feb;566(7745):553-557. doi: 10.1038/s41586-019-0915-y. Epub 2019 Feb 6.


Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties.

Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W.

Adv Mater. 2019 Mar;31(12):e1806727. doi: 10.1002/adma.201806727. Epub 2019 Jan 27.


Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 68Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques.

Varasteh Z, Mohanta S, Li Y, López Armbruster N, Braeuer M, Nekolla SG, Habenicht A, Sager HB, Raes G, Weber W, Hernot S, Schwaiger M.

EJNMMI Res. 2019 Jan 21;9(1):5. doi: 10.1186/s13550-019-0474-0.


Optogenetic control of integrin-matrix interaction.

Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W.

Commun Biol. 2019 Jan 8;2:15. doi: 10.1038/s42003-018-0264-7. eCollection 2019.


Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding.

Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Aceto N.

Cell. 2019 Jan 10;176(1-2):98-112.e14. doi: 10.1016/j.cell.2018.11.046.


Expression of RET is associated with Oestrogen receptor expression but lacks prognostic significance in breast cancer.

Mechera R, Soysal SD, Piscuoglio S, Ng CKY, Zeindler J, Mujagic E, Däster S, Glauser P, Hoffmann H, Kilic E, Droeser RA, Weber WP, Muenst S.

BMC Cancer. 2019 Jan 8;19(1):41. doi: 10.1186/s12885-018-5262-0.


T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target.

Mayer KE, Mall S, Yusufi N, Gosmann D, Steiger K, Russelli L, Bianchi HO, Audehm S, Wagner R, Bräunlein E, Stelzl A, Bassermann F, Weichert W, Weber W, Schwaiger M, D'Alessandria C, Krackhardt AM.

Theranostics. 2018 Nov 28;8(21):6070-6087. doi: 10.7150/thno.27275. eCollection 2018.


Pragmatic clinical trials offer unique opportunities for disseminating, implementing, and sustaining evidence-based practices into clinical care: Proceedings of a workshop.

Tuzzio L, Larson EB, Chambers DA, Coronado GD, Curtis LH, Weber WJ, Zatzick DF, Meyers CM.

Healthc (Amst). 2019 Mar;7(1):51-57. doi: 10.1016/j.hjdsi.2018.12.003. Epub 2018 Dec 26. Review.


QuanTP: A Software Resource for Quantitative Proteo-Transcriptomic Comparative Data Analysis and Informatics.

Kumar P, Panigrahi P, Johnson J, Weber WJ, Mehta S, Sajulga R, Easterly C, Crooker BA, Heydarian M, Anamika K, Griffin TJ, Jagtap PD.

J Proteome Res. 2019 Feb 1;18(2):782-790. doi: 10.1021/acs.jproteome.8b00727. Epub 2019 Jan 4.


Pitfalls in Ga-68-PSMA-PET/CT: incidental finding of parathyroid adenoma.

Pfob CH, Karimov I, Jesinghaus M, Novotny A, Weber WA, Eiber M, Feuerecker B.

Eur J Nucl Med Mol Imaging. 2019 Apr;46(4):1041. doi: 10.1007/s00259-018-4239-1. Epub 2018 Dec 19. No abstract available.


Consensus on molecular imaging and theranostics in prostate cancer.

Fanti S, Minozzi S, Antoch G, Banks I, Briganti A, Carrio I, Chiti A, Clarke N, Eiber M, De Bono J, Fizazi K, Gillessen S, Gledhill S, Haberkorn U, Herrmann K, Hicks RJ, Lecouvet F, Montironi R, Ost P, O'Sullivan JM, Padhani AR, Schalken JA, Scher HI, Tombal B, van Moorselaar RJA, Van Poppel H, Vargas HA, Walz J, Weber WA, Wester HJ, Oyen WJG.

Lancet Oncol. 2018 Dec;19(12):e696-e708. doi: 10.1016/S1470-2045(18)30604-1. Review.


Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with clinically node-positive breast cancer (TAXIS): study protocol for a multicenter, randomized phase-III trial.

Henke G, Knauer M, Ribi K, Hayoz S, Gérard MA, Ruhstaller T, Zwahlen DR, Muenst S, Ackerknecht M, Hawle H, Fitzal F, Gnant M, Mátrai Z, Ballardini B, Gyr A, Kurzeder C, Weber WP.

Trials. 2018 Dec 4;19(1):667. doi: 10.1186/s13063-018-3021-9.


Prognostic value of baseline metabolic tumor volume measured on 18F-fluorodeoxyglucose positron emission tomography/computed tomography in melanoma patients treated with ipilimumab therapy.

Ito K, Schöder H, Teng R, Humm JL, Ni A, Wolchok JD, Weber WA.

Eur J Nucl Med Mol Imaging. 2019 Apr;46(4):930-939. doi: 10.1007/s00259-018-4211-0. Epub 2018 Nov 28.


Treatment Outcome, Toxicity, and Predictive Factors for Radioligand Therapy with 177Lu-PSMA-I&T in Metastatic Castration-resistant Prostate Cancer.

Heck MM, Tauber R, Schwaiger S, Retz M, D'Alessandria C, Maurer T, Gafita A, Wester HJ, Gschwend JE, Weber WA, Schwaiger M, Knorr K, Eiber M.

Eur Urol. 2019 Jun;75(6):920-926. doi: 10.1016/j.eururo.2018.11.016. Epub 2018 Nov 22.


Fibroepithelial Breast Lesion: When Sequencing Can Help to Make a Clinical Decision. A Case Report.

Montagna G, Ng CKY, Vlajnic T, Paradiso V, Dellas S, Reina H, Kind A, Weber WP, Piscuoglio S, Kurzeder C.

Clin Breast Cancer. 2019 Feb;19(1):e1-e6. doi: 10.1016/j.clbc.2018.10.007. Epub 2018 Nov 1. No abstract available.


EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer.

Sanchez-Vega F, Hechtman JF, Castel P, Ku GY, Tuvy Y, Won H, Fong CJ, Bouvier N, Nanjangud GJ, Soong J, Vakiani E, Schattner M, Kelsen DP, Lefkowitz RA, Brown K, Lacouture ME, Capanu M, Mattar M, Qeriqi B, Cecchi F, Tian Y, Hembrough T, Nagy RJ, Lanman RB, Larson SM, Pandit-Taskar N, Schöder H, Iacobuzio-Donahue CA, Ilson DH, Weber WA, Berger MF, de Stanchina E, Taylor BS, Lewis JS, Solit DB, Carrasquillo JA, Scaltriti M, Schultz N, Janjigian YY.

Cancer Discov. 2019 Feb;9(2):199-209. doi: 10.1158/2159-8290.CD-18-0598. Epub 2018 Nov 21.


Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer.

Vetter M, Landin J, Szczerba BM, Castro-Giner F, Gkountela S, Donato C, Krol I, Scherrer R, Balmelli C, Malinovska A, Zippelius A, Kurzeder C, Heinzelmann-Schwarz V, Weber WP, Rochlitz C, Aceto N.

Breast Cancer Res. 2018 Nov 20;20(1):141. doi: 10.1186/s13058-018-1067-y.


Early Experience of Rechallenge 177Lu-PSMA Radioligand Therapy After an Initial Good Response in Patients with Advanced Prostate Cancer.

Gafita A, Rauscher I, Retz M, Knorr K, Heck M, Wester HJ, D'Alessandria C, Weber WA, Eiber M, Tauber R.

J Nucl Med. 2019 May;60(5):644-648. doi: 10.2967/jnumed.118.215715. Epub 2018 Nov 15.


18F-FDG PET/CT for Monitoring of Ipilimumab Therapy in Patients with Metastatic Melanoma.

Ito K, Teng R, Schöder H, Humm JL, Ni A, Michaud L, Nakajima R, Yamashita R, Wolchok JD, Weber WA.

J Nucl Med. 2019 Mar;60(3):335-341. doi: 10.2967/jnumed.118.213652. Epub 2018 Nov 9.


A Two-Step Approach for the Design and Generation of Nanobodies.

Wagner HJ, Wehrle S, Weiss E, Cavallari M, Weber W.

Int J Mol Sci. 2018 Nov 2;19(11). pii: E3444. doi: 10.3390/ijms19113444.


ASO Author Reflections: Abandoning the Drains by Eliminating the Radical Procedures Necessitating the Drains.

Weber WP.

Ann Surg Oncol. 2018 Dec;25(Suppl 3):671-672. doi: 10.1245/s10434-018-6965-9. Epub 2018 Oct 29. No abstract available.


Biodistribution and radiation dose estimates for 68Ga-DOTA-JR11 in patients with metastatic neuroendocrine tumors.

Krebs S, Pandit-Taskar N, Reidy D, Beattie BJ, Lyashchenko SK, Lewis JS, Bodei L, Weber WA, O'Donoghue JA.

Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):677-685. doi: 10.1007/s00259-018-4193-y. Epub 2018 Oct 29.


Galectin-3 Targeting in Thyroid Orthotopic Tumors Opens New Ways to Characterize Thyroid Cancer.

De Rose F, Braeuer M, Braesch-Andersen S, Otto AM, Steiger K, Reder S, Mall S, Nekolla S, Schwaiger M, Weber WA, Bartolazzi A, D'Alessandria C.

J Nucl Med. 2019 Jun;60(6):770-776. doi: 10.2967/jnumed.118.219105. Epub 2018 Oct 25.


Genetic Code Expansion Method for Temporal Labeling of Endogenously Expressed Proteins.

Schneider N, Gäbelein C, Wiener J, Georgiev T, Gobet N, Weber W, Meier M.

ACS Chem Biol. 2018 Nov 16;13(11):3049-3053. doi: 10.1021/acschembio.8b00594. Epub 2018 Oct 17.


Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells.

Baaske J, Gonschorek P, Engesser R, Dominguez-Monedero A, Raute K, Fischbach P, Müller K, Cachat E, Schamel WWA, Minguet S, Davies JA, Timmer J, Weber W, Zurbriggen MD.

Sci Rep. 2018 Oct 9;8(1):15024. doi: 10.1038/s41598-018-32929-7.


Sibling rivalry: Males with more brothers develop larger testes.

Fisher HS, Hook KA, Weber WD, Hoekstra HE.

Ecol Evol. 2018 Jul 22;8(16):8197-8203. doi: 10.1002/ece3.4337. eCollection 2018 Aug.


Correction to: Effect of radiochemotherapy on T2* MRI in HNSCC and its relation to FMISO PET derived hypoxia and FDG PET.

Wiedenmann N, Bunea H, Rischke HC, Bunea A, Majerus L, Bielak L, Protopopov A, Ludwig U, Büchert M, Stoykow C, Nicolay NH, Weber WA, Mix M, Meyer PT, Hennig J, Bock M, Grosu AL.

Radiat Oncol. 2018 Sep 21;13(1):183. doi: 10.1186/s13014-018-1134-7.


Diffusion-weighted MRI and ADC versus FET-PET and GdT1w-MRI for gross tumor volume (GTV) delineation in re-irradiation of recurrent glioblastoma.

Popp I, Bott S, Mix M, Oehlke O, Schimek-Jasch T, Nieder C, Nestle U, Bock M, Yuh WTC, Meyer PT, Weber WA, Urbach H, Mader I, Grosu AL.

Radiother Oncol. 2019 Jan;130:121-131. doi: 10.1016/j.radonc.2018.08.019. Epub 2018 Sep 12.


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