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Items: 1 to 50 of 90

1.

A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.

Dai W, Laforest B, Tyan L, Shen KM, Nadadur RD, Alvarado FJ, Mazurek SR, Lazarevic S, Gadek M, Wang Y, Li Y, Valdivia HH, Shen L, Broman MT, Moskowitz IP, Weber CR.

Elife. 2019 Mar 21;8. pii: e41814. doi: 10.7554/eLife.41814.

2.

The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation.

Wang Y, Li Y, Zou J, Polster SP, Lightle R, Moore T, Dimaano M, He TC, Weber CR, Awad IA, Shen L.

FASEB J. 2019 Feb;33(2):2132-2143. doi: 10.1096/fj.201800343R. Epub 2018 Sep 25.

PMID:
30252535
3.

Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors.

Romero-Calvo I, Weber CR, Ray M, Brown M, Kirby K, Nandi RK, Long TM, Sparrow SM, Ugolkov A, Qiang W, Zhang Y, Brunetti T, Kindler H, Segal JP, Rzhetsky A, Mazar AP, Buschmann MM, Weichselbaum R, Roggin K, White KP.

Mol Cancer Res. 2019 Jan;17(1):70-83. doi: 10.1158/1541-7786.MCR-18-0531. Epub 2018 Aug 31.

PMID:
30171177
4.

The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis.

Overstreet AM, LaTorre DL, Abernathy-Close L, Murphy SF, Rhee L, Boger AM, Adlaka KR, Iverson AM, Bakke DS, Weber CR, Boone DL.

Mucosal Immunol. 2018 Sep;11(5):1454-1465. doi: 10.1038/s41385-018-0051-2. Epub 2018 Jul 9.

5.

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis.

Mason DM, Weber CR, Parola C, Meng SM, Greiff V, Kelton WJ, Reddy ST.

Nucleic Acids Res. 2018 Aug 21;46(14):7436-7449. doi: 10.1093/nar/gky550.

6.

Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis.

Sofia MA, Ciorba MA, Meckel K, Lim CK, Guillemin GJ, Weber CR, Bissonnette M, Pekow JR.

Inflamm Bowel Dis. 2018 Jun 8;24(7):1471-1480. doi: 10.1093/ibd/izy103.

PMID:
29796641
7.

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B.

Nature. 2018 May;557(7706):580-584. doi: 10.1038/s41586-018-0125-z. Epub 2018 May 16.

8.

Safety and Efficacy of Combination Treatment With Calcineurin Inhibitors and Vedolizumab in Patients With Refractory Inflammatory Bowel Disease.

Christensen B, Gibson PR, Micic D, Colman RJ, Goeppinger SR, Kassim O, Yarur A, Weber CR, Cohen RD, Rubin DT.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):486-493. doi: 10.1016/j.cgh.2018.04.060. Epub 2018 May 8.

PMID:
29751166
9.

Vedolizumab as Induction and Maintenance for Inflammatory Bowel Disease: 12-month Effectiveness and Safety.

Christensen B, Colman RJ, Micic D, Gibson PR, Goeppinger SR, Yarur A, Weber CR, Cohen RD, Rubin DT.

Inflamm Bowel Dis. 2018 Mar 19;24(4):849-860. doi: 10.1093/ibd/izx067.

10.

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires.

Miho E, Yermanos A, Weber CR, Berger CT, Reddy ST, Greiff V.

Front Immunol. 2018 Feb 21;9:224. doi: 10.3389/fimmu.2018.00224. eCollection 2018. Review.

11.

Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm.

Yang XH, Nadadur RD, Hilvering CR, Bianchi V, Werner M, Mazurek SR, Gadek M, Shen KM, Goldman JA, Tyan L, Bekeny J, Hall JM, Lee N, Perez-Cervantes C, Burnicka-Turek O, Poss KD, Weber CR, de Laat W, Ruthenburg AJ, Moskowitz IP.

Elife. 2017 Dec 27;6. pii: e31683. doi: 10.7554/eLife.31683.

12.

Unusual gastric subepithelial tumor: primary mixed acinar-endocrine neoplasm in an anemic woman.

Uraizee I, Hart J, Waxman I, Weber CR, Setia N.

Gastrointest Endosc. 2018 May;87(5):1355-1356. doi: 10.1016/j.gie.2017.10.014. Epub 2017 Nov 2. No abstract available.

PMID:
29102730
13.

Learning the High-Dimensional Immunogenomic Features That Predict Public and Private Antibody Repertoires.

Greiff V, Weber CR, Palme J, Bodenhofer U, Miho E, Menzel U, Reddy ST.

J Immunol. 2017 Oct 15;199(8):2985-2997. doi: 10.4049/jimmunol.1700594. Epub 2017 Sep 18.

14.

Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon.

Krugliak Cleveland N, Rubin DT, Hart J, Weber CR, Meckel K, Tran AL, Aelvoet AS, Pan I, Gonsalves A, Gaetano JN, Williams KM, Wroblewski K, Jabri B, Pekow J.

Clin Gastroenterol Hepatol. 2018 Jan;16(1):68-74. doi: 10.1016/j.cgh.2017.07.023. Epub 2017 Jul 26.

15.

Publisher's Note: X-ray shadow imprint of hydrodynamic instabilities on the surface of inertial confinement fusion capsules by the fuel fill tube [Phys. Rev. E 95, 031204(R) (2017)].

MacPhee AG, Casey DT, Clark DS, Felker S, Field JE, Haan SW, Hammel BA, Kroll J, Landen OL, Martinez DA, Michel P, Milovich J, Moore A, Nikroo A, Rice N, Robey HF, Smalyuk VA, Stadermann M, Weber CR.

Phys Rev E. 2017 Jun;95(6-2):069905. doi: 10.1103/PhysRevE.95.069905. Epub 2017 Jun 27.

PMID:
28709236
16.

Dynamic modeling of the tight junction pore pathway.

Weber CR, Turner JR.

Ann N Y Acad Sci. 2017 Jun;1397(1):209-218. doi: 10.1111/nyas.13374. Epub 2017 Jun 12.

17.

X-ray shadow imprint of hydrodynamic instabilities on the surface of inertial confinement fusion capsules by the fuel fill tube.

MacPhee AG, Casey DT, Clark DS, Felker S, Field JE, Haan SW, Hammel BA, Kroll J, Landen OL, Martinez DA, Michel P, Milovich J, Moore A, Nikroo A, Rice N, Robey HF, Smalyuk VA, Stadermann M, Weber CR.

Phys Rev E. 2017 Mar;95(3-1):031204. doi: 10.1103/PhysRevE.95.031204. Epub 2017 Mar 30. Erratum in: Phys Rev E. 2017 Jun;95(6-2):069905.

PMID:
28415208
18.

Development of a krypton-doped gas symmetry capsule platform for x-ray spectroscopy of implosion cores on the NIF.

Ma T, Chen H, Patel PK, Schneider MB, Barrios MA, Casey DT, Chung HK, Hammel BA, Berzak Hopkins LF, Jarrott LC, Khan SF, Lahmann B, Nora R, Rosenberg MJ, Pak A, Regan SP, Scott HA, Sio H, Spears BK, Weber CR.

Rev Sci Instrum. 2016 Nov;87(11):11E327.

PMID:
27910341
19.

Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.

Wali RK, Momi N, Dela Cruz M, Calderwood AH, Stypula-Cyrus Y, Almassalha L, Chhaparia A, Weber CR, Radosevich A, Tiwari AK, Latif B, Backman V, Roy HK.

Cancer Prev Res (Phila). 2016 Nov;9(11):844-854. Epub 2016 Aug 22.

20.

Erratum: First Measurements of Fuel-Ablator Interface Instability Growth in Inertial Confinement Fusion Implosions on the National Ignition Facility [Phys. Rev. Lett. 117, 075002 (2016)].

Weber CR, Döppner T, Casey DT, Bunn TL, Carlson LC, Dylla-Spears RJ, Kozioziemski BJ, MacPhee AG, Nikroo A, Robey HF, Sater JD, Smalyuk VA.

Phys Rev Lett. 2016 Oct 7;117(15):159902. Epub 2016 Oct 7.

PMID:
27768355
21.

Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis.

Meisel M, Mayassi T, Fehlner-Peach H, Koval JC, O'Brien SL, Hinterleitner R, Lesko K, Kim S, Bouziat R, Chen L, Weber CR, Mazmanian SK, Jabri B, Antonopoulos DA.

ISME J. 2017 Jan;11(1):15-30. doi: 10.1038/ismej.2016.114. Epub 2016 Sep 20.

22.

Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.

Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, Efimov IR, McNally EM, Weber CR, Moskowitz IP.

Sci Transl Med. 2016 Aug 31;8(354):354ra115. doi: 10.1126/scitranslmed.aaf4891.

23.

First Measurements of Fuel-Ablator Interface Instability Growth in Inertial Confinement Fusion Implosions on the National Ignition Facility.

Weber CR, Döppner T, Casey DT, Bunn TL, Carlson LC, Dylla-Spears RJ, Kozioziemski BJ, MacPhee AG, Nikroo A, Robey HF, Sater JD, Smalyuk VA.

Phys Rev Lett. 2016 Aug 12;117(7):075002. doi: 10.1103/PhysRevLett.117.075002. Epub 2016 Aug 9. Erratum in: Phys Rev Lett. 2016 Oct 7;117(15):159902.

PMID:
27563971
24.

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.

McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R.

Sci Rep. 2016 Jul 14;6:29179. doi: 10.1038/srep29179.

25.

Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility.

Ward MA, Pierre JF, Leal RF, Huang Y, Shogan B, Dalal SR, Weber CR, Leone VA, Musch MW, An GC, Rao MC, Rubin DT, Raffals LE, Antonopoulos DA, Sogin ML, Hyman NH, Alverdy JC, Chang EB.

Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G973-88. doi: 10.1152/ajpgi.00017.2016. Epub 2016 Apr 14.

26.

Claudin-2-dependent paracellular channels are dynamically gated.

Weber CR, Liang GH, Wang Y, Das S, Shen L, Yu AS, Nelson DJ, Turner JR.

Elife. 2015 Nov 14;4:e09906. doi: 10.7554/eLife.09906.

27.

Spectral biomarkers for chemoprevention of colonic neoplasia: a placebo-controlled double-blinded trial with aspirin.

Roy HK, Turzhitsky V, Wali R, Radosevich AJ, Jovanovic B, Della'Zanna G, Umar A, Rubin DT, Goldberg MJ, Bianchi L, De La Cruz M, Bogojevic A, Helenowski IB, Rodriguez L, Chatterton R, Skripkauskas S, Page K, Weber CR, Huang X, Richmond E, Bergan RC, Backman V.

Gut. 2017 Feb;66(2):285-292. doi: 10.1136/gutjnl-2015-309996. Epub 2015 Oct 26.

28.

S&R Foundation 15th Anniversary.

Staruschenko A, Weber CR, Pochynyuk O, McCole DF.

Physiologist. 2015 Sep;58(5):241-2. No abstract available.

PMID:
26442383
29.

Improved Performance of High Areal Density Indirect Drive Implosions at the National Ignition Facility using a Four-Shock Adiabat Shaped Drive.

Casey DT, Milovich JL, Smalyuk VA, Clark DS, Robey HF, Pak A, MacPhee AG, Baker KL, Weber CR, Ma T, Park HS, Döppner T, Callahan DA, Haan SW, Patel PK, Peterson JL, Hoover D, Nikroo A, Yeamans CB, Merrill FE, Volegov PL, Fittinghoff DN, Grim GP, Edwards MJ, Landen OL, Lafortune KN, MacGowan BJ, Widmayer CC, Sayre DB, Hatarik R, Bond EJ, Nagel SR, Benedetti LR, Izumi N, Khan S, Bachmann B, Spears BK, Cerjan CJ, Gatu Johnson M, Frenje JA.

Phys Rev Lett. 2015 Sep 4;115(10):105001. Epub 2015 Sep 1.

PMID:
26382681
30.

Antrum Mucosal Protein-18 Peptide Targets Tight Junctions to Protect and Heal Barrier Structure and Function in Models of Inflammatory Bowel Disease.

Chen P, Bakke D, Kolodziej L, Lodolce J, Weber CR, Boone DL, Toback FG.

Inflamm Bowel Dis. 2015 Oct;21(10):2393-2402. doi: 10.1097/MIB.0000000000000499.

31.

The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon.

Grimm WA, Messer JS, Murphy SF, Nero T, Lodolce JP, Weber CR, Logsdon MF, Bartulis S, Sylvester BE, Springer A, Dougherty U, Niewold TB, Kupfer SS, Ellis N, Huo D, Bissonnette M, Boone DL.

Gut. 2016 Mar;65(3):456-64. doi: 10.1136/gutjnl-2014-308735. Epub 2015 Feb 2.

32.

Inhibition of turbulence in inertial-confinement-fusion hot spots by viscous dissipation.

Weber CR, Clark DS, Cook AW, Busby LE, Robey HF.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 May;89(5):053106. Epub 2014 May 27.

PMID:
25353903
33.

Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.

Murphy SF, Rhee L, Grimm WA, Weber CR, Messer JS, Lodolce JP, Chang JE, Bartulis SJ, Nero T, Kukla RA, MacDougall G, Binghay C, Kolodziej LE, Boone DL.

Am J Physiol Gastrointest Liver Physiol. 2014 Nov 1;307(9):G871-82. doi: 10.1152/ajpgi.00020.2014. Epub 2014 Sep 18.

34.

Molecular aspects of tight junction barrier function.

Liang GH, Weber CR.

Curr Opin Pharmacol. 2014 Dec;19:84-9. doi: 10.1016/j.coph.2014.07.017. Epub 2014 Aug 14. Review.

35.

Chronic pouchitis versus recurrent Crohn's disease: a diagnostic challenge.

Weber CR, Rubin DT.

Dig Dis Sci. 2013 Oct;58(10):2748-50. doi: 10.1007/s10620-013-2816-5. Epub 2013 Aug 8. No abstract available.

36.

Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux.

Buschmann MM, Shen L, Rajapakse H, Raleigh DR, Wang Y, Wang Y, Lingaraju A, Zha J, Abbott E, McAuley EM, Breskin LA, Wu L, Anderson K, Turner JR, Weber CR.

Mol Biol Cell. 2013 Oct;24(19):3056-68. doi: 10.1091/mbc.E12-09-0688. Epub 2013 Aug 7.

37.

FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.

Qi W, Fitchev PS, Cornwell ML, Greenberg J, Cabe M, Weber CR, Roy HK, Crawford SE, Savkovic SD.

J Biol Chem. 2013 Jun 7;288(23):16274-81. doi: 10.1074/jbc.M113.470617. Epub 2013 Apr 18.

38.

Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis.

Bergmann KR, Liu SX, Tian R, Kushnir A, Turner JR, Li HL, Chou PM, Weber CR, De Plaen IG.

Am J Pathol. 2013 May;182(5):1595-606. doi: 10.1016/j.ajpath.2013.01.013. Epub 2013 Mar 5.

39.

Cardiac Na+-Ca2+ exchanger: dynamics of Ca2+-dependent activation and deactivation in intact myocytes.

Ginsburg KS, Weber CR, Bers DM.

J Physiol. 2013 Apr 15;591(8):2067-86. doi: 10.1113/jphysiol.2013.252080. Epub 2013 Feb 11.

40.

Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1.

Bouyer PG, Tang X, Weber CR, Shen L, Turner JR, Matthews JB.

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15;304(2):G142-56. doi: 10.1152/ajpgi.00483.2011. Epub 2012 Nov 8.

41.

Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response.

Wali RK, Kunte DP, De La Cruz M, Tiwari AK, Brasky J, Weber CR, Gibson TP, Patel A, Savkovic SD, Brockstein BE, Roy HK.

PLoS One. 2012;7(6):e38047. doi: 10.1371/journal.pone.0038047. Epub 2012 Jun 4.

42.

Dynamic properties of the tight junction barrier.

Weber CR.

Ann N Y Acad Sci. 2012 Jun;1257:77-84. doi: 10.1111/j.1749-6632.2012.06528.x.

43.

Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis.

Rhee L, Murphy SF, Kolodziej LE, Grimm WA, Weber CR, Lodolce JP, Chang JE, Bartulis SJ, Messer JS, Schneider JR, Paski S, Nero TM, Boone DL.

Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15;303(2):G220-7. doi: 10.1152/ajpgi.00077.2012. Epub 2012 May 17.

44.

Dynamic migration of γδ intraepithelial lymphocytes requires occludin.

Edelblum KL, Shen L, Weber CR, Marchiando AM, Clay BS, Wang Y, Prinz I, Malissen B, Sperling AI, Turner JR.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):7097-102. doi: 10.1073/pnas.1112519109. Epub 2012 Apr 17.

45.

Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides.

Frantz AL, Rogier EW, Weber CR, Shen L, Cohen DA, Fenton LA, Bruno ME, Kaetzel CS.

Mucosal Immunol. 2012 Sep;5(5):501-12. doi: 10.1038/mi.2012.23. Epub 2012 Apr 11.

46.

Polyethylene glycol diminishes pathological effects of Citrobacter rodentium infection by blocking bacterial attachment to the colonic epithelia.

Qi W, Joshi S, Weber CR, Wali RK, Roy HK, Savkovic SD.

Gut Microbes. 2011 Sep 1;2(5):267-73. doi: 10.4161/gmic.2.5.18256. Epub 2011 Sep 1.

47.
48.

Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function.

Raleigh DR, Boe DM, Yu D, Weber CR, Marchiando AM, Bradford EM, Wang Y, Wu L, Schneeberger EE, Shen L, Turner JR.

J Cell Biol. 2011 May 2;193(3):565-82. doi: 10.1083/jcb.201010065.

49.

Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.

Qi W, Weber CR, Wasland K, Roy H, Wali R, Joshi S, Savkovic SD.

Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G264-72. doi: 10.1152/ajpgi.00416.2010. Epub 2010 Nov 25.

50.

Tight junction pore and leak pathways: a dynamic duo.

Shen L, Weber CR, Raleigh DR, Yu D, Turner JR.

Annu Rev Physiol. 2011;73:283-309. doi: 10.1146/annurev-physiol-012110-142150. Review.

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