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Multiphoton microscopy: a potential "optical biopsy" tool for real-time evaluation of lung tumors without the need for exogenous contrast agents.

Jain M, Narula N, Aggarwal A, Stiles B, Shevchuk MM, Sterling J, Salamoon B, Chandel V, Webb WW, Altorki NK, Mukherjee S.

Arch Pathol Lab Med. 2014 Aug;138(8):1037-47. doi: 10.5858/arpa.2013-0122-OA. Epub 2013 Nov 7.


Miniature varifocal objective lens for endomicroscopy.

Ouzounov DG, Rivera DR, Webb WW, Bentley J, Xu C.

Opt Lett. 2013 Aug 15;38(16):3103-6. doi: 10.1364/OL.38.003103.


Dual modality endomicroscope with optical zoom capability.

Ouzounov DG, Rivera DR, Williams WO, Stupinski JA, Southard TL, Hume KH, Bentley J, Weiss RS, Webb WW, Xu C.

Biomed Opt Express. 2013 Aug 1;4(9):1494-503. doi: 10.1364/BOE.4.001494. eCollection 2013.


Interplay between desolvation and secondary structure in mediating cosolvent and temperature induced alpha-synuclein aggregation.

Anderson VL, Webb WW, Eliezer D.

Phys Biol. 2012 Oct;9(5):056005. doi: 10.1088/1478-3975/9/5/056005. Epub 2012 Aug 29.


In vivo imaging of unstained tissues using long gradient index lens multiphoton endoscopic systems.

Huland DM, Brown CM, Howard SS, Ouzounov DG, Pavlova I, Wang K, Rivera DR, Webb WW, Xu C.

Biomed Opt Express. 2012 May 1;3(5):1077-85. doi: 10.1364/BOE.3.001077. Epub 2012 Apr 19.


In vivo imaging of unstained tissues using a compact and flexible multiphoton microendoscope.

Brown CM, Rivera DR, Pavlova I, Ouzounov DG, Williams WO, Mohanan S, Webb WW, Xu C.

J Biomed Opt. 2012 Apr;17(4):040505. doi: 10.1117/1.JBO.17.4.040505.


Multiphoton microscopy in the evaluation of human bladder biopsies.

Jain M, Robinson BD, Scherr DS, Sterling J, Lee MM, Wysock J, Rubin MA, Maxfield FR, Zipfel WR, Webb WW, Mukherjee S.

Arch Pathol Lab Med. 2012 May;136(5):517-26. doi: 10.5858/arpa.2011-0147-OA.


Multifocal multiphoton endoscope.

Rivera DR, Brown CM, Ouzounov DG, Webb WW, Xu C.

Opt Lett. 2012 Apr 15;37(8):1349-51. doi: 10.1364/OL.37.001349.


Multiphoton microscopy and microspectroscopy for diagnostics of inflammatory and neoplastic lung.

Pavlova I, Hume KR, Yazinski SA, Flanders J, Southard TL, Weiss RS, Webb WW.

J Biomed Opt. 2012 Mar;17(3):036014. doi: 10.1117/1.JBO.17.3.036014.


A desolvation model for trifluoroethanol-induced aggregation of enhanced green fluorescent protein.

Anderson VL, Webb WW.

Biophys J. 2012 Feb 22;102(4):897-906. doi: 10.1016/j.bpj.2012.01.036. Epub 2012 Feb 21.


Use of a lensed fiber for a large-field-of-view, high-resolution, fiber-scanning microendoscope.

Rivera DR, Brown CM, Ouzounov DG, Webb WW, Xu C.

Opt Lett. 2012 Mar 1;37(5):881-3. doi: 10.1364/OL.37.000881.


Ionic strength-dependent persistence lengths of single-stranded RNA and DNA.

Chen H, Meisburger SP, Pabit SA, Sutton JL, Webb WW, Pollack L.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):799-804. doi: 10.1073/pnas.1119057109. Epub 2011 Dec 27.


Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregates.

Anderson VL, Webb WW.

BMC Biotechnol. 2011 Dec 19;11:125. doi: 10.1186/1472-6750-11-125.


Compact and flexible raster scanning multiphoton endoscope capable of imaging unstained tissue.

Rivera DR, Brown CM, Ouzounov DG, Pavlova I, Kobat D, Webb WW, Xu C.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17598-603. doi: 10.1073/pnas.1114746108. Epub 2011 Oct 17.


Dopamine-induced oscillations of the pyloric pacemaker neuron rely on release of calcium from intracellular stores.

Kadiri LR, Kwan AC, Webb WW, Harris-Warrick RM.

J Neurophysiol. 2011 Sep;106(3):1288-98. doi: 10.1152/jn.00456.2011. Epub 2011 Jun 15.


Multiphoton microscopy for structure identification in human prostate and periprostatic tissue: implications in prostate cancer surgery.

Tewari AK, Shevchuk MM, Sterling J, Grover S, Herman M, Yadav R, Mudalair K, Srivastava A, Rubin MA, Zipfel WR, Maxfield FR, Xu C, Webb WW, Mukherjee S.

BJU Int. 2011 Nov;108(9):1421-9. doi: 10.1111/j.1464-410X.2011.10169.x. Epub 2011 Mar 28.


Response to Kang et al.

Brust-Mascher I, Baird BA, Webb WW.

Biophys J. 2011 Feb 2;100(3):793-794. doi: 10.1016/j.bpj.2010.11.090. Epub 2011 Feb 1. No abstract available.


Multiphoton polarization imaging of steady-state molecular order in ternary lipid vesicles for the purpose of lipid phase assignment.

Farkas ER, Webb WW.

J Phys Chem B. 2010 Dec 2;114(47):15512-22. doi: 10.1021/jp107025h. Epub 2010 Nov 8.


Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation.

Anderson VL, Ramlall TF, Rospigliosi CC, Webb WW, Eliezer D.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18850-5. doi: 10.1073/pnas.1012336107. Epub 2010 Oct 14.


Spatiotemporal dynamics of rhythmic spinal interneurons measured with two-photon calcium imaging and coherence analysis.

Kwan AC, Dietz SB, Zhong G, Harris-Warrick RM, Webb WW.

J Neurophysiol. 2010 Dec;104(6):3323-33. doi: 10.1152/jn.00679.2010. Epub 2010 Sep 22.


Endoscope lens with dual fields of view and resolutions for multiphoton imaging.

Chen M, Xu C, Webb WW.

Opt Lett. 2010 Aug 15;35(16):2735-7. doi: 10.1364/OL.35.002735.


Complex molecular dynamics in the spotlight.

Pollack L, Webb WW.

Nat Biotechnol. 2010 Jun;28(6):564-5. doi: 10.1038/nbt0610-564. No abstract available.


Mechanisms of quenching of Alexa fluorophores by natural amino acids.

Chen H, Ahsan SS, Santiago-Berrios MB, Abruña HD, Webb WW.

J Am Chem Soc. 2010 Jun 2;132(21):7244-5. doi: 10.1021/ja100500k.


Multiphoton microscopy as a diagnostic imaging modality for lung cancer.

Pavlova I, Hume KR, Yazinski SA, Peters RM, Weiss RS, Webb WW.

Proc SPIE Int Soc Opt Eng. 2010 Jan 24;7569:756918.


GUV preparation and imaging: minimizing artifacts.

Morales-Penningston NF, Wu J, Farkas ER, Goh SL, Konyakhina TM, Zheng JY, Webb WW, Feigenson GW.

Biochim Biophys Acta. 2010 Jul;1798(7):1324-32. doi: 10.1016/j.bbamem.2010.03.011. Epub 2010 Mar 17. Review.


Electrophysiological characterization of V2a interneurons and their locomotor-related activity in the neonatal mouse spinal cord.

Zhong G, Droho S, Crone SA, Dietz S, Kwan AC, Webb WW, Sharma K, Harris-Warrick RM.

J Neurosci. 2010 Jan 6;30(1):170-82. doi: 10.1523/JNEUROSCI.4849-09.2010.


Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord.

Kwan AC, Dietz SB, Webb WW, Harris-Warrick RM.

J Neurosci. 2009 Sep 16;29(37):11601-13. doi: 10.1523/JNEUROSCI.1612-09.2009.


Multiphoton microscopy of prostate and periprostatic neural tissue: a promising imaging technique for improving nerve-sparing prostatectomy.

Yadav R, Mukherjee S, Hermen M, Tan G, Maxfield FR, Webb WW, Tewari AK.

J Endourol. 2009 May;23(5):861-7. doi: 10.1089/end.2009.0221.


Human bladder cancer diagnosis using Multiphoton microscopy.

Mukherjee S, Wysock JS, Ng CK, Akhtar M, Perner S, Lee MM, Rubin MA, Maxfield FR, Webb WW, Scherr DS.

Proc SPIE Int Soc Opt Eng. 2009;7161. pii: nihpa96839.


Spt6 enhances the elongation rate of RNA polymerase II in vivo.

Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT.

EMBO J. 2009 Apr 22;28(8):1067-77. doi: 10.1038/emboj.2009.56. Epub 2009 Mar 12.


Chapter 1: In vivo applications of fluorescence correlation spectroscopy.

Chen H, Farkas ER, Webb WW.

Methods Cell Biol. 2008;89:3-35. doi: 10.1016/S0091-679X(08)00601-8.


Polarized microtubule arrays in apical dendrites and axons.

Kwan AC, Dombeck DA, Webb WW.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11370-5. doi: 10.1073/pnas.0805199105. Epub 2008 Aug 5.


Imaging transcription dynamics at endogenous genes in living Drosophila tissues.

Yao J, Zobeck KL, Lis JT, Webb WW.

Methods. 2008 Jul;45(3):233-41. doi: 10.1016/j.ymeth.2008.06.004. Epub 2008 Jun 27.


Two-Photon Fluorescence Excitation Cross Sections of Biomolecular Probes from 690 to 960 nm.

Albota MA, Xu C, Webb WW.

Appl Opt. 1998 Nov 1;37(31):7352-6.


Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer.

Park HY, Kim SA, Korlach J, Rhoades E, Kwok LW, Zipfel WR, Waxham MN, Webb WW, Pollack L.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):542-7. doi: 10.1073/pnas.0710810105. Epub 2008 Jan 4.


Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation.

Yao J, Ardehali MB, Fecko CJ, Webb WW, Lis JT.

Mol Cell. 2007 Dec 28;28(6):978-90.


P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo.

Ni Z, Saunders A, Fuda NJ, Yao J, Suarez JR, Webb WW, Lis JT.

Mol Cell Biol. 2008 Feb;28(3):1161-70. Epub 2007 Dec 10.


Comparison of femtosecond laser and continuous wave UV sources for protein-nucleic acid crosslinking.

Fecko CJ, Munson KM, Saunders A, Sun G, Begley TP, Lis JT, Webb WW.

Photochem Photobiol. 2007 Nov-Dec;83(6):1394-404.


Delivery of nanojoule femtosecond pulses through large-core microstructured fibers.

Ouzounov DG, Moll KD, Foster MA, Zipfel WR, Webb WW, Gaeta AL.

Opt Lett. 2002 Sep 1;27(17):1513-5.


Heterogeneous effects of dopamine on highly localized, voltage-induced Ca2+ accumulation in identified motoneurons.

Kloppenburg P, Zipfel WR, Webb WW, Harris-Warrick RM.

J Neurophysiol. 2007 Nov;98(5):2910-7. Epub 2007 Aug 29.


Fluorescence probe partitioning between Lo/Ld phases in lipid membranes.

Baumgart T, Hunt G, Farkas ER, Webb WW, Feigenson GW.

Biochim Biophys Acta. 2007 Sep;1768(9):2182-94. Epub 2007 May 21.


Serotonin modulates dendritic calcium influx in commissural interneurons in the mouse spinal locomotor network.

Díaz-Ríos M, Dombeck DA, Webb WW, Harris-Warrick RM.

J Neurophysiol. 2007 Oct;98(4):2157-67. Epub 2007 Jun 20.


Dynamics of equilibrium structural fluctuations of apomyoglobin measured by fluorescence correlation spectroscopy.

Chen H, Rhoades E, Butler JS, Loh SN, Webb WW.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10459-64. Epub 2007 Jun 7.


Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles.

Baumgart T, Hammond AT, Sengupta P, Hess ST, Holowka DA, Baird BA, Webb WW.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3165-70. Epub 2007 Feb 21.


Dynamics of heat shock factor association with native gene loci in living cells.

Yao J, Munson KM, Webb WW, Lis JT.

Nature. 2006 Aug 31;442(7106):1050-3. Epub 2006 Aug 23.


Achieving uniform mixing in a microfluidic device: hydrodynamic focusing prior to mixing.

Park HY, Qiu X, Rhoades E, Korlach J, Kwok LW, Zipfel WR, Webb WW, Pollack L.

Anal Chem. 2006 Jul 1;78(13):4465-73.


Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy.

Rhoades E, Ramlall TF, Webb WW, Eliezer D.

Biophys J. 2006 Jun 15;90(12):4692-700. Epub 2006 Mar 31.

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