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Items: 1 to 50 of 123

1.

Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome.

Dufek S, Cheshire C, Levine AP, Trompeter RS, Issler N, Stubbs M, Mozere M, Gupta S, Klootwijk E, Patel V, Hothi D, Waters A, Webb H, Tullus K, Jenkins L, Godinho L, Levtchenko E, Wetzels J, Knoers N, Teeninga N, Nauta J, Shalaby M, Eldesoky S, Kari JA, Thalgahagoda S, Ranawaka R, Abeyagunawardena A, Adeyemo A, Kristiansen M, Gbadegesin R, Webb NJ, Gale DP, Stanescu HC, Kleta R, Bockenhauer D.

J Am Soc Nephrol. 2019 Jul 1. pii: ASN.2018101054. doi: 10.1681/ASN.2018101054. [Epub ahead of print]

PMID:
31263063
2.

Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome: the PREDNOS RCT.

Webb NJ, Woolley RL, Lambe T, Frew E, Brettell EA, Barsoum EN, Trompeter RS, Cummins C, Wheatley K, Ives NJ.

Health Technol Assess. 2019 May;23(26):1-108. doi: 10.3310/hta23260.

3.

Comparative pharmacokinetics of tacrolimus in stable pediatric allograft recipients converted from immediate-release tacrolimus to prolonged-release tacrolimus formulation.

Rubik J, Debray D, Iserin F, Vondrak K, Sellier-Leclerc AL, Kelly D, Czubkowski P, Webb NJA, Riva S, D'Antiga L, Marks SD, Rivet C, Tönshoff B, Kazeem G, Undre N.

Pediatr Transplant. 2019 Jun;23(4):e13391. doi: 10.1111/petr.13391. Epub 2019 Apr 1.

PMID:
30932313
4.

Identifying Important Outcomes for Young People With CKD and Their Caregivers: A Nominal Group Technique Study.

Hanson CS, Gutman T, Craig JC, Bernays S, Raman G, Zhang Y, James LJ, Ralph AF, Ju A, Manera KE, Teixeira-Pinto A, Viecelli AK, Alexander SI, Blydt-Hansen TD, Dionne J, McTaggart S, Michael M, Walker A, Carter S, Wenderfer SE, Winkelmayer WC, Bockenhauer D, Dart A, Eddy AA, Furth SL, Gipson DS, Goldstein SL, Groothoff J, Samuel S, Sinha A, Webb NJA, Yap HK, Zappitelli M, Currier H, Tong A.

Am J Kidney Dis. 2019 Jul;74(1):82-94. doi: 10.1053/j.ajkd.2018.12.040. Epub 2019 Mar 15.

PMID:
30885704
5.

Pharmacokinetics of tacrolimus granules in pediatric de novo liver, kidney, and heart transplantation: The OPTION study.

Webb NJA, Baumann U, Camino M, Frauca E, Undre N; OPTION Study Group.

Pediatr Transplant. 2019 Feb;23(1):e13328. doi: 10.1111/petr.13328. Epub 2019 Jan 21.

PMID:
30665258
6.

Comparative pharmacokinetics of tacrolimus in de novo pediatric transplant recipients randomized to receive immediate- or prolonged-release tacrolimus.

Vondrak K, Dhawan A, Parisi F, Grenda R, Debray D, Marks SD, Webb NJA, Lachaux A, Kazeem G, Undre N.

Pediatr Transplant. 2018 Dec;22(8):e13289. doi: 10.1111/petr.13289. Epub 2018 Oct 24.

PMID:
30358019
7.

Child and Parental Perspectives on Communication and Decision Making in Pediatric CKD: A Focus Group Study.

Gutman T, Hanson CS, Bernays S, Craig JC, Sinha A, Dart A, Eddy AA, Gipson DS, Bockenhauer D, Yap HK, Groothoff J, Zappitelli M, Webb NJA, Alexander SI, Goldstein SL, Furth S, Samuel S, Blydt-Hansen T, Dionne J, Michael M, Wenderfer SE, Winkelmayer WC, Currier H, McTaggart S, Walker A, Ralph AF, Ju A, James LJ, Carter S, Tong A.

Am J Kidney Dis. 2018 Oct;72(4):547-559. doi: 10.1053/j.ajkd.2018.05.005. Epub 2018 Jul 3.

PMID:
29980375
8.

Insights and implications of new blood pressure guidelines in children and adolescents.

Lurbe E, Litwin M, Pall D, Seeman T, Stabouli S, Webb NJA, Wühl E; Working Group of the 2016 European Society of Hypertension Guidelines for the Management of High Blood Pressure in Children and Adolescents.

J Hypertens. 2018 Jul;36(7):1456-1459. doi: 10.1097/HJH.0000000000001761. No abstract available.

PMID:
29677052
9.

Patterns and frequency of renal abnormalities in Fanconi anaemia: implications for long-term management.

Sathyanarayana V, Lee B, Wright NB, Santos R, Bonney D, Wynn R, Patel L, Chandler K, Cheesman E, Schindler D, Webb NJA, Meyer S.

Pediatr Nephrol. 2018 Sep;33(9):1547-1551. doi: 10.1007/s00467-018-3952-0. Epub 2018 Apr 12.

10.

Vaccination titres pre- and post-transplant in paediatric renal transplant recipients and the impact of immunosuppressive therapy.

Höcker B, Aguilar M, Schnitzler P, Pape L, Bald M, König J, Marks SD, Genc G, Büscher A, Kemper MJ, Billing H, Pohl M, Dello Strologo L, Webb NJA, Rieger S, Mankertz A, Krupka K, Bruckner T, Fichtner A, Tönshoff B.

Pediatr Nephrol. 2018 May;33(5):897-910. doi: 10.1007/s00467-017-3868-0. Epub 2018 Jan 10.

PMID:
29322328
11.

Mapping the Paediatric Quality of Life Inventory (PedsQL™) Generic Core Scales onto the Child Health Utility Index-9 Dimension (CHU-9D) Score for Economic Evaluation in Children.

Lambe T, Frew E, Ives NJ, Woolley RL, Cummins C, Brettell EA, Barsoum EN, Webb NJA; PREDNOS Trial Team.

Pharmacoeconomics. 2018 Apr;36(4):451-465. doi: 10.1007/s40273-017-0600-7.

PMID:
29264866
12.

Incomplete vaccination coverage in European children with end-stage kidney disease prior to renal transplantation.

Höcker B, Aguilar M, Schnitzler P, Pape L, Dello Strologo L, Webb NJA, Bald M, Genc G, Billing H, König J, Büscher A, Kemper MJ, Marks SD, Pohl M, Wigger M, Topaloglu R, Rieger S, Krupka K, Bruckner T, Fichtner A, Tönshoff B.

Pediatr Nephrol. 2018 Feb;33(2):341-350. doi: 10.1007/s00467-017-3776-3. Epub 2017 Oct 5.

PMID:
28983694
13.

Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1.

McCaffrey JC, Webb NJ, Poolman TM, Fresquet M, Moxey C, Zeef LAH, Donaldson IJ, Ray DW, Lennon R.

Sci Rep. 2017 Jul 27;7(1):6725. doi: 10.1038/s41598-017-06810-y.

14.

Range and Heterogeneity of Outcomes in Randomized Trials of Pediatric Chronic Kidney Disease.

Chong LSH, Sautenet B, Tong A, Hanson CS, Samuel S, Zappitelli M, Dart A, Furth S, Eddy AA, Groothoff J, Webb NJA, Yap HK, Bockenhauer D, Sinha A, Alexander SI, Goldstein SL, Gipson DS, Raman G, Craig JC.

J Pediatr. 2017 Jul;186:110-117.e11. doi: 10.1016/j.jpeds.2017.03.034. Epub 2017 Apr 24.

PMID:
28449820
15.

Dyslipidemia after pediatric renal transplantation-The impact of immunosuppressive regimens.

Habbig S, Volland R, Krupka K, Querfeld U, Dello Strologo L, Noyan A, Yalcinkaya F, Topaloglu R, Webb NJ, Kemper MJ, Pape L, Bald M, Kranz B, Taylan C, Höcker B, Tönshoff B, Weber LT.

Pediatr Transplant. 2017 May;21(3). doi: 10.1111/petr.12914. Epub 2017 Mar 28.

PMID:
28370750
16.

Efficacy and safety of paricalcitol in children with stages 3 to 5 chronic kidney disease.

Webb NJA, Lerner G, Warady BA, Dell KM, Greenbaum LA, Ariceta G, Hoppe B, Linde P, Lee HJ, Eldred A, Dufek MB.

Pediatr Nephrol. 2017 Jul;32(7):1221-1232. doi: 10.1007/s00467-017-3579-6. Epub 2017 Mar 22.

17.

Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management.

Bierzynska A, McCarthy HJ, Soderquest K, Sen ES, Colby E, Ding WY, Nabhan MM, Kerecuk L, Hegde S, Hughes D, Marks S, Feather S, Jones C, Webb NJ, Ognjanovic M, Christian M, Gilbert RD, Sinha MD, Lord GM, Simpson M, Koziell AB, Welsh GI, Saleem MA.

Kidney Int. 2017 Apr;91(4):937-947. doi: 10.1016/j.kint.2016.10.013. Epub 2017 Jan 20.

PMID:
28117080
18.

Standardised Outcomes in Nephrology-Children and Adolescents (SONG-Kids): a protocol for establishing a core outcome set for children with chronic kidney disease.

Tong A, Samuel S, Zappitelli M, Dart A, Furth S, Eddy A, Groothoff J, Webb NJ, Yap HK, Bockenhauer D, Sinha A, Alexander SI, Goldstein SL, Gipson DS, Hanson CS, Evangelidis N, Crowe S, Harris T, Hemmelgarn BR, Manns B, Gill J, Tugwell P, Van Biesen W, Wheeler DC, Winkelmayer WC, Craig JC; SONG-Kids Investigators.

Trials. 2016 Aug 12;17:401. doi: 10.1186/s13063-016-1528-5.

19.

Recent developments in the detection and management of acute kidney injury.

McCaffrey J, Dhakal AK, Milford DV, Webb NJ, Lennon R.

Arch Dis Child. 2017 Jan;102(1):91-96. doi: 10.1136/archdischild-2015-309381. Epub 2016 Aug 5. Review.

20.

2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents.

Lurbe E, Agabiti-Rosei E, Cruickshank JK, Dominiczak A, Erdine S, Hirth A, Invitti C, Litwin M, Mancia G, Pall D, Rascher W, Redon J, Schaefer F, Seeman T, Sinha M, Stabouli S, Webb NJ, Wühl E, Zanchetti A.

J Hypertens. 2016 Oct;34(10):1887-920. doi: 10.1097/HJH.0000000000001039.

PMID:
27467768
21.

Cytomegalovirus Infection in Pediatric Renal Transplantation and the Impact of Chemoprophylaxis With (Val-)Ganciclovir.

Höcker B, Zencke S, Krupka K, Fichtner A, Pape L, Dello Strologo L, Guzzo I, Topaloglu R, Kranz B, König J, Bald M, Webb NJ, Noyan A, Dursun H, Marks S, Yalcinkaya F, Thiel F, Billing H, Pohl M, Fehrenbach H, Bruckner T, Tönshoff B.

Transplantation. 2016 Apr;100(4):862-70. doi: 10.1097/TP.0000000000000888.

PMID:
26736017
22.

Single-dose pharmacokinetics and safety of azilsartan medoxomil in children and adolescents with hypertension as compared to healthy adults.

Webb NJ, Wells T, Tsai M, Zhao Z, Juhasz A, Dudkowski C.

Eur J Clin Pharmacol. 2016 Apr;72(4):447-57. doi: 10.1007/s00228-015-1987-8. Epub 2016 Jan 4.

23.

Impact of Everolimus and Low-Dose Cyclosporin on Cytomegalovirus Replication and Disease in Pediatric Renal Transplantation.

Höcker B, Zencke S, Pape L, Krupka K, Köster L, Fichtner A, Dello Strologo L, Guzzo I, Topaloglu R, Kranz B, König J, Bald M, Webb NJ, Noyan A, Dursun H, Marks S, Ozcakar ZB, Thiel F, Billing H, Pohl M, Fehrenbach H, Schnitzler P, Bruckner T, Ahlenstiel-Grunow T, Tönshoff B.

Am J Transplant. 2016 Mar;16(3):921-9. doi: 10.1111/ajt.13649. Epub 2016 Feb 3.

24.

The non-immunosuppressive management of childhood nephrotic syndrome.

McCaffrey J, Lennon R, Webb NJ.

Pediatr Nephrol. 2016 Sep;31(9):1383-402. doi: 10.1007/s00467-015-3241-0. Epub 2015 Nov 10. Review.

25.

Evolving concepts in tumour lysis syndrome management - response to Ayed et al.

Jones GL, Will A, Jackson GH, Webb NJ, Rule S.

Br J Haematol. 2016 May;173(3):486-7. doi: 10.1111/bjh.13616. Epub 2015 Jul 27. No abstract available.

PMID:
26216044
26.

Towards a biomarker panel for the assessment of AKI in children receiving intensive care.

McCaffrey J, Coupes B, Chaloner C, Webb NJ, Barber R, Lennon R.

Pediatr Nephrol. 2015 Oct;30(10):1861-71. doi: 10.1007/s00467-015-3089-3. Epub 2015 Apr 15.

27.

Guidelines for the management of tumour lysis syndrome in adults and children with haematological malignancies on behalf of the British Committee for Standards in Haematology.

Jones GL, Will A, Jackson GH, Webb NJ, Rule S; British Committee for Standards in Haematology.

Br J Haematol. 2015 Jun;169(5):661-71. doi: 10.1111/bjh.13403. Epub 2015 Apr 15. No abstract available.

PMID:
25876990
28.

Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.

Lennon R, Stuart HM, Bierzynska A, Randles MJ, Kerr B, Hillman KA, Batra G, Campbell J, Storey H, Flinter FA, Koziell A, Welsh GI, Saleem MA, Webb NJ, Woolf AS.

Pediatr Nephrol. 2015 Sep;30(9):1459-65. doi: 10.1007/s00467-015-3067-9. Epub 2015 Mar 5.

29.

Corticosteroid-free Kidney Transplantation Improves Growth: 2-Year Follow-up of the TWIST Randomized Controlled Trial.

Webb NJ, Douglas SE, Rajai A, Roberts SA, Grenda R, Marks SD, Watson AR, Fitzpatrick M, Vondrak K, Maxwell H, Jaray J, Van Damme-Lombaerts R, Milford DV, Godefroid N, Cochat P, Ognjanovic M, Murer L, McCulloch M, Tönshoff B.

Transplantation. 2015 Jun;99(6):1178-85. doi: 10.1097/TP.0000000000000498.

PMID:
25539467
30.

HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome.

Gbadegesin RA, Adeyemo A, Webb NJ, Greenbaum LA, Abeyagunawardena A, Thalgahagoda S, Kale A, Gipson D, Srivastava T, Lin JJ, Chand D, Hunley TE, Brophy PD, Bagga A, Sinha A, Rheault MN, Ghali J, Nicholls K, Abraham E, Janjua HS, Omoloja A, Barletta GM, Cai Y, Milford DD, O'Brien C, Awan A, Belostotsky V, Smoyer WE, Homstad A, Hall G, Wu G, Nagaraj S, Wigfall D, Foreman J, Winn MP; Mid-West Pediatric Nephrology Consortium.

J Am Soc Nephrol. 2015 Jul;26(7):1701-10. doi: 10.1681/ASN.2014030247. Epub 2014 Oct 27.

31.

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.

Malone AF, Phelan PJ, Hall G, Cetincelik U, Homstad A, Alonso AS, Jiang R, Lindsey TB, Wu G, Sparks MA, Smith SR, Webb NJ, Kalra PA, Adeyemo AA, Shaw AS, Conlon PJ, Jennette JC, Howell DN, Winn MP, Gbadegesin RA.

Kidney Int. 2014 Dec;86(6):1253-9. doi: 10.1038/ki.2014.305. Epub 2014 Sep 17.

32.

Rhodium(III)-catalyzed C-H activation/annulation with vinyl esters as an acetylene equivalent.

Webb NJ, Marsden SP, Raw SA.

Org Lett. 2014 Sep 19;16(18):4718-21. doi: 10.1021/ol502095z. Epub 2014 Aug 28.

33.

A novel Interactive Health Communication Application (IHCA) for parents of children with long-term conditions: Development, implementation and feasibility assessment.

Swallow V, Carolan I, Smith T, Webb NJ, Knafl K, Santacroce S, Campbell M, Harper-Jones M, Hanif N, Hall A.

Inform Health Soc Care. 2016;41(1):20-46. doi: 10.3109/17538157.2014.948174. Epub 2014 Aug 13.

PMID:
25119067
34.

A randomized, open-label, dose-response study of losartan in hypertensive children.

Webb NJ, Wells TG, Shahinfar S, Massaad R, Dankner WM, Lam C, Santoro EP, McCrary Sisk C, Blaustein RO.

Clin J Am Soc Nephrol. 2014 Aug 7;9(8):1441-8. doi: 10.2215/CJN.11111113. Epub 2014 May 29.

35.

Distributed expertise: qualitative study of a British network of multidisciplinary teams supporting parents of children with chronic kidney disease.

Swallow V, Smith T, Webb NJ, Wirz L, Qizalbash L, Brennan E, Birch A, Sinha MD, Krischock L, van der Voort J, King D, Lambert H, Milford DV, Crowther L, Saleem M, Lunn A, Williams J.

Child Care Health Dev. 2015 Jan;41(1):67-75. doi: 10.1111/cch.12141. Epub 2014 May 14.

36.

Short course daily prednisolone therapy during an upper respiratory tract infection in children with relapsing steroid-sensitive nephrotic syndrome (PREDNOS 2): protocol for a randomised controlled trial.

Webb NJ, Frew E, Brettell EA, Milford DV, Bockenhauer D, Saleem MA, Christian M, Hall AS, Koziell A, Maxwell H, Hegde S, Finlay ER, Gilbert RD, Booth J, Jones C, McKeever K, Cook W, Ives NJ; PREDNOS 2 study group.

Trials. 2014 Apr 27;15:147. doi: 10.1186/1745-6215-15-147.

37.

Bladder dysfunction and hypertension in children with Guillain-Barre syndrome.

Watson L, Aziz M, Vassallo G, Plant ND, Webb NJ.

Pediatr Nephrol. 2014 Sep;29(9):1637-41. doi: 10.1007/s00467-014-2799-2. Epub 2014 Mar 22.

PMID:
24651942
38.

Pediatric kidney recipients may benefit from monitoring for donor-specific antibodies.

Athavale D, Worthington J, Webb NJ, Roberts D, Martin S, Shenoy M.

Pediatr Transplant. 2014 May;18(3):258-65. doi: 10.1111/petr.12247. Epub 2014 Mar 20.

PMID:
24646402
39.

Designing a web-application to support home-based care of childhood CKD stages 3-5: qualitative study of family and professional preferences.

Swallow VM, Hall AG, Carolan I, Santacroce S, Webb NJ, Smith T, Hanif N.

BMC Nephrol. 2014 Feb 18;15:34. doi: 10.1186/1471-2369-15-34.

40.

Successful ABO incompatible renal transplantation following rituximab and DFPP after failed immunoadsorption.

Thalgahagoda S, Webb NJ, Roberts D, Birch A, Milford DV, Tavakoli A, Shenoy M.

Pediatr Transplant. 2014 May;18(3):E74-6. doi: 10.1111/petr.12227. Epub 2014 Feb 1.

PMID:
24483150
41.

Unmet needs in the measurement of blood pressure in primary care.

Zaheer S, Watson L, Webb NJ.

Arch Dis Child. 2014 May;99(5):463-4. doi: 10.1136/archdischild-2013-305277. Epub 2014 Jan 15.

PMID:
24431416
42.

Multidisciplinary teams, and parents, negotiating common ground in shared-care of children with long-term conditions: a mixed methods study.

Swallow VM, Nightingale R, Williams J, Lambert H, Webb NJ, Smith T, Wirz L, Qizalbash L, Crowther L, Allen D.

BMC Health Serv Res. 2013 Jul 8;13:264. doi: 10.1186/1472-6963-13-264.

43.

The CERTAIN Registry: a novel, web-based registry and research platform for pediatric renal transplantation in Europe.

Plotnicki L, Kohl CD, Höcker B, Krupka K, Rahmel A, Pape L, Hoyer P, Marks SD, Webb NJ, Söylemezoglu O, Topaloglu R, Szabo AJ, Seeman T, Marlies Cornelissen EA, Knops N, Grenda R, Tönshoff B.

Transplant Proc. 2013 May;45(4):1414-7. doi: 10.1016/j.transproceed.2013.01.007.

PMID:
23726585
44.

Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.

McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA; RADAR the UK SRNS Study Group.

Clin J Am Soc Nephrol. 2013 Apr;8(4):637-48. doi: 10.2215/CJN.07200712. Epub 2013 Jan 24.

45.

Losartan and enalapril are comparable in reducing proteinuria in children with Alport syndrome.

Webb NJ, Shahinfar S, Wells TG, Massaad R, Gleim GW, McCrary Sisk C, Lam C.

Pediatr Nephrol. 2013 May;28(5):737-43. doi: 10.1007/s00467-012-2372-9. Epub 2012 Dec 4.

PMID:
23207876
46.

Losartan and enalapril are comparable in reducing proteinuria in children.

Webb NJ, Shahinfar S, Wells TG, Massaad R, Gleim GW, Santoro EP, Sisk CM, Lam C.

Kidney Int. 2012 Oct;82(7):819-26. doi: 10.1038/ki.2012.210. Epub 2012 Jun 27.

47.

Assessing children's and parents' opinions on salivary sampling for therapeutic drug monitoring.

Swallow V, Hughes J, Roberts D, Webb NJ.

Nurse Res. 2012;19(3):32-7.

PMID:
22662376
48.

Pseudohyperkalaemia associated with leukaemic cell lysis during pneumatic tube transport of blood samples.

Dickinson H, Webb NJ, Chaloner C, Wynn RF, Bonney DK.

Pediatr Nephrol. 2012 Jun;27(6):1029-31. doi: 10.1007/s00467-012-2102-3. Epub 2012 Feb 26.

PMID:
22366875
49.

Pan-Britain, mixed-methods study of multidisciplinary teams teaching parents to manage children's long-term kidney conditions at home: study protocol.

Swallow VM, Allen D, Williams J, Smith T, Crosier J, Lambert H, Qizalbash L, Wirz L, Webb NJ.

BMC Health Serv Res. 2012 Feb 14;12:33. doi: 10.1186/1472-6963-12-33.

50.

The Online Parent Information and Support project, meeting parents' information and support needs for home-based management of childhood chronic kidney disease: research protocol.

Swallow V, Knafl K, Sanatacroce S, Hall A, Smith T, Campbell M, Webb NJ.

J Adv Nurs. 2012 Sep;68(9):2095-102. doi: 10.1111/j.1365-2648.2011.05908.x. Epub 2012 Jan 8.

PMID:
22224560

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