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Items: 1 to 50 of 78

1.

Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.

Soren O, Rineh A, Silva DG, Cai Y, Howlin RP, Allan RN, Feelisch M, Davies JC, Connett GJ, Faust SN, Kelso MJ, Webb JS.

J Antimicrob Chemother. 2019 Sep 17. pii: dkz378. doi: 10.1093/jac/dkz378. [Epub ahead of print]

PMID:
31682251
2.

Evaluation of a Bioengineered Honey and Its Synthetic Equivalent as Novel Staphylococcus aureus Biofilm-Targeted Topical Therapies in Chronic Rhinosinusitis.

Papadopoulou D, Dabrowska A, Harries PG, Webb JS, Allan RN, Salib RJ.

Am J Rhinol Allergy. 2019 Sep 11:1945892419874700. doi: 10.1177/1945892419874700. [Epub ahead of print] No abstract available.

PMID:
31510757
3.

Microbial epidemiology and carriage studies for the evaluation of vaccines.

Coughtrie AL, Jefferies JM, Cleary DW, Doncaster CP, Faust SN, Kraaijeveld AR, Moore MV, Mullee MA, Roderick PJ, Webb JS, Yuen HM, Clarke SC.

J Med Microbiol. 2019 Oct;68(10):1408-1418. doi: 10.1099/jmm.0.001046. Review.

PMID:
31418679
4.

Diagnosis and treatment of biofilm infections in children.

Munro APS, Highmore CJ, Webb JS, Faust SN.

Curr Opin Infect Dis. 2019 Oct;32(5):505-509. doi: 10.1097/QCO.0000000000000582.

PMID:
31335442
5.

Rhizosphere Bacterial Communities Differ According to Fertilizer Regimes and Cabbage (Brassica oleracea var. capitata L.) Harvest Time, but Not Aphid Herbivory.

O'Brien FJM, Dumont MG, Webb JS, Poppy GM.

Front Microbiol. 2018 Jul 23;9:1620. doi: 10.3389/fmicb.2018.01620. eCollection 2018.

6.

Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis.

Smith WD, Bardin E, Cameron L, Edmondson CL, Farrant KV, Martin I, Murphy RA, Soren O, Turnbull AR, Wierre-Gore N, Alton EW, Bundy JG, Bush A, Connett GJ, Faust SN, Filloux A, Freemont PS, Jones AL, Takats Z, Webb JS, Williams HD, Davies JC.

FEMS Microbiol Lett. 2017 Aug 1;364(14). doi: 10.1093/femsle/fnx121. Review.

PMID:
28854668
7.

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

Howlin RP, Cathie K, Hall-Stoodley L, Cornelius V, Duignan C, Allan RN, Fernandez BO, Barraud N, Bruce KD, Jefferies J, Kelso M, Kjelleberg S, Rice SA, Rogers GB, Pink S, Smith C, Sukhtankar PS, Salib R, Legg J, Carroll M, Daniels T, Feelisch M, Stoodley P, Clarke SC, Connett G, Faust SN, Webb JS.

Mol Ther. 2017 Sep 6;25(9):2104-2116. doi: 10.1016/j.ymthe.2017.06.021. Epub 2017 Jul 24.

8.

Pneumococcal conjugate vaccine implementation in middle-income countries.

Tricarico S, McNeil HC, Cleary DW, Head MG, Lim V, Yap IKS, Wie CC, Tan CS, Norazmi MN, Aziah I, Cheah ESG, Faust SN, Jefferies JMC, Roderick PJ, Moore M, Yuen HM, Newell ML, McGrath N, Doncaster CP, Kraaijeveld AR, Webb JS, Clarke SC.

Pneumonia (Nathan). 2017 Mar 25;9:6. doi: 10.1186/s41479-017-0030-5. eCollection 2017. Review.

9.

Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms.

Allan RN, Kelso MJ, Rineh A, Yepuri NR, Feelisch M, Soren O, Brito-Mutunayagam S, Salib RJ, Stoodley P, Clarke SC, Webb JS, Hall-Stoodley L, Faust SN.

Nitric Oxide. 2017 May 1;65:43-49. doi: 10.1016/j.niox.2017.02.006. Epub 2017 Feb 21.

PMID:
28235635
10.

Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.

Bellini D, Horrell S, Hutchin A, Phippen CW, Strange RW, Cai Y, Wagner A, Webb JS, Tews I, Walsh MA.

Sci Rep. 2017 Feb 10;7:42166. doi: 10.1038/srep42166.

11.

Prevention of Propionibacterium acnes biofilm formation in prosthetic infections in vitro.

Howlin RP, Winnard C, Angus EM, Frapwell CJ, Webb JS, Cooper JJ, Aiken SS, Bishop JY, Stoodley P.

J Shoulder Elbow Surg. 2017 Apr;26(4):553-563. doi: 10.1016/j.jse.2016.09.042. Epub 2016 Dec 15.

PMID:
27989720
12.

Cephalosporin-3'-Diazeniumdiolate NO Donor Prodrug PYRRO-C3D Enhances Azithromycin Susceptibility of Nontypeable Haemophilus influenzae Biofilms.

Collins SA, Kelso MJ, Rineh A, Yepuri NR, Coles J, Jackson CL, Halladay GD, Walker WT, Webb JS, Hall-Stoodley L, Connett GJ, Feelisch M, Faust SN, Lucas JS, Allan RN.

Antimicrob Agents Chemother. 2017 Jan 24;61(2). pii: e02086-16. doi: 10.1128/AAC.02086-16. Print 2017 Feb.

13.

Biofilm prevention of gram-negative bacterial pathogens involved in periprosthetic infection by antibiotic-loaded calcium sulfate beads in vitro.

Howlin RP, Winnard C, Frapwell CJ, Webb JS, Cooper JJ, Aiken SS, Stoodley P.

Biomed Mater. 2016 Dec 2;12(1):015002.

PMID:
27910828
14.

Parallel Evolution in Streptococcus pneumoniae Biofilms.

Churton NW, Misra RV, Howlin RP, Allan RN, Jefferies J, Faust SN, Gharbia SE, Edwards RJ, Clarke SC, Webb JS.

Genome Biol Evol. 2016 May 9;8(5):1316-26. doi: 10.1093/gbe/evw072.

15.

Comparative Genomics of Carriage and Disease Isolates of Streptococcus pneumoniae Serotype 22F Reveals Lineage-Specific Divergence and Niche Adaptation.

Cleary DW, Devine VT, Jefferies JM, Webb JS, Bentley SD, Gladstone RA, Faust SN, Clarke SC.

Genome Biol Evol. 2016 Apr 21;8(4):1243-51. doi: 10.1093/gbe/evw066.

16.

Low Concentrations of Nitric Oxide Modulate Streptococcus pneumoniae Biofilm Metabolism and Antibiotic Tolerance.

Allan RN, Morgan S, Brito-Mutunayagam S, Skipp P, Feelisch M, Hayes SM, Hellier W, Clarke SC, Stoodley P, Burgess A, Ismail-Koch H, Salib RJ, Webb JS, Faust SN, Hall-Stoodley L.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2456-66. doi: 10.1128/AAC.02432-15. Print 2016 Apr.

17.

Removal of Dental Biofilms with an Ultrasonically Activated Water Stream.

Howlin RP, Fabbri S, Offin DG, Symonds N, Kiang KS, Knee RJ, Yoganantham DC, Webb JS, Birkin PR, Leighton TG, Stoodley P.

J Dent Res. 2015 Sep;94(9):1303-9. doi: 10.1177/0022034515589284. Epub 2015 Jun 8.

PMID:
26056055
18.

Genetics, genomics and evolution of ergot alkaloid diversity.

Young CA, Schardl CL, Panaccione DG, Florea S, Takach JE, Charlton ND, Moore N, Webb JS, Jaromczyk J.

Toxins (Basel). 2015 Apr 14;7(4):1273-302. doi: 10.3390/toxins7041273. Review.

19.

Intracellular residency of Staphylococcus aureus within mast cells in nasal polyps: A novel observation.

Hayes SM, Howlin R, Johnston DA, Webb JS, Clarke SC, Stoodley P, Harries PG, Wilson SJ, Pender SL, Faust SN, Hall-Stoodley L, Salib RJ.

J Allergy Clin Immunol. 2015 Jun;135(6):1648-51. doi: 10.1016/j.jaci.2014.12.1929. Epub 2015 Feb 11. No abstract available.

PMID:
25680455
20.

Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator.

Phippen CW, Mikolajek H, Schlaefli HG, Keevil CW, Webb JS, Tews I.

FEBS Lett. 2014 Dec 20;588(24):4631-6. doi: 10.1016/j.febslet.2014.11.002. Epub 2014 Nov 11.

21.

Antibiotic-loaded synthetic calcium sulfate beads for prevention of bacterial colonization and biofilm formation in periprosthetic infections.

Howlin RP, Brayford MJ, Webb JS, Cooper JJ, Aiken SS, Stoodley P.

Antimicrob Agents Chemother. 2015 Jan;59(1):111-20. doi: 10.1128/AAC.03676-14. Epub 2014 Oct 13.

22.

Strain-specific parallel evolution drives short-term diversification during Pseudomonas aeruginosa biofilm formation.

McElroy KE, Hui JG, Woo JK, Luk AW, Webb JS, Kjelleberg S, Rice SA, Thomas T.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1419-27. doi: 10.1073/pnas.1314340111. Epub 2014 Mar 28.

23.

Selection of orphan Rhs toxin expression in evolved Salmonella enterica serovar Typhimurium.

Koskiniemi S, Garza-Sánchez F, Sandegren L, Webb JS, Braaten BA, Poole SJ, Andersson DI, Hayes CS, Low DA.

PLoS Genet. 2014 Mar 27;10(3):e1004255. doi: 10.1371/journal.pgen.1004255. eCollection 2014 Mar.

24.

Currencies of mutualisms: sources of alkaloid genes in vertically transmitted epichloae.

Schardl CL, Young CA, Pan J, Florea S, Takach JE, Panaccione DG, Farman ML, Webb JS, Jaromczyk J, Charlton ND, Nagabhyru P, Chen L, Shi C, Leuchtmann A.

Toxins (Basel). 2013 Jun 6;5(6):1064-88. doi: 10.3390/toxins5061064.

25.

Delivery of CdiA nuclease toxins into target cells during contact-dependent growth inhibition.

Webb JS, Nikolakakis KC, Willett JL, Aoki SK, Hayes CS, Low DA.

PLoS One. 2013;8(2):e57609. doi: 10.1371/journal.pone.0057609. Epub 2013 Feb 28.

26.

Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci.

Schardl CL, Young CA, Hesse U, Amyotte SG, Andreeva K, Calie PJ, Fleetwood DJ, Haws DC, Moore N, Oeser B, Panaccione DG, Schweri KK, Voisey CR, Farman ML, Jaromczyk JW, Roe BA, O'Sullivan DM, Scott B, Tudzynski P, An Z, Arnaoudova EG, Bullock CT, Charlton ND, Chen L, Cox M, Dinkins RD, Florea S, Glenn AE, Gordon A, Güldener U, Harris DR, Hollin W, Jaromczyk J, Johnson RD, Khan AK, Leistner E, Leuchtmann A, Li C, Liu J, Liu J, Liu M, Mace W, Machado C, Nagabhyru P, Pan J, Schmid J, Sugawara K, Steiner U, Takach JE, Tanaka E, Webb JS, Wilson EV, Wiseman JL, Yoshida R, Zeng Z.

PLoS Genet. 2013;9(2):e1003323. doi: 10.1371/journal.pgen.1003323. Epub 2013 Feb 28.

27.

Cephalosporin-3'-diazeniumdiolates: targeted NO-donor prodrugs for dispersing bacterial biofilms.

Barraud N, Kardak BG, Yepuri NR, Howlin RP, Webb JS, Faust SN, Kjelleberg S, Rice SA, Kelso MJ.

Angew Chem Int Ed Engl. 2012 Sep 3;51(36):9057-60. doi: 10.1002/anie.201202414. Epub 2012 Aug 13.

PMID:
22890975
28.

Biofilm dispersal cells of a cystic fibrosis Pseudomonas aeruginosa isolate exhibit variability in functional traits likely to contribute to persistent infection.

Woo JK, Webb JS, Kirov SM, Kjelleberg S, Rice SA.

FEMS Immunol Med Microbiol. 2012 Nov;66(2):251-64. doi: 10.1111/j.1574-695X.2012.01006.x. Epub 2012 Jul 31.

29.

Can Simpson's paradox explain co-operation in Pseudomonas aeruginosa biofilms?

Penn AS, Conibear TC, Watson RA, Kraaijeveld AR, Webb JS.

FEMS Immunol Med Microbiol. 2012 Jul;65(2):226-35. doi: 10.1111/j.1574-695X.2012.00970.x. Epub 2012 Apr 23.

30.

Identification of a target cell permissive factor required for contact-dependent growth inhibition (CDI).

Diner EJ, Beck CM, Webb JS, Low DA, Hayes CS.

Genes Dev. 2012 Mar 1;26(5):515-25. doi: 10.1101/gad.182345.111. Epub 2012 Feb 14.

31.

Down-regulation of DNA mismatch repair enhances initiation and growth of neuroblastoma and brain tumour multicellular spheroids.

Collins SL, Hervé R, Keevil CW, Blaydes JP, Webb JS.

PLoS One. 2011;6(12):e28123. doi: 10.1371/journal.pone.0028123. Epub 2011 Dec 1.

32.

Dynamic modelling of cell death during biofilm development.

Fagerlind MG, Webb JS, Barraud N, McDougald D, Jansson A, Nilsson P, Harlén M, Kjelleberg S, Rice SA.

J Theor Biol. 2012 Feb 21;295:23-36. doi: 10.1016/j.jtbi.2011.10.007. Epub 2011 Nov 11.

PMID:
22100489
33.

Risk of red queen dynamics in pneumococcal vaccine strategy.

Jefferies JM, Clarke SC, Webb JS, Kraaijeveld AR.

Trends Microbiol. 2011 Aug;19(8):377-81. doi: 10.1016/j.tim.2011.06.001. Epub 2011 Jul 15.

PMID:
21763141
34.

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria.

Aoki SK, Diner EJ, de Roodenbeke CT, Burgess BR, Poole SJ, Braaten BA, Jones AM, Webb JS, Hayes CS, Cotter PA, Low DA.

Nature. 2010 Nov 18;468(7322):439-42. doi: 10.1038/nature09490.

35.

Ability of Pseudoalteromonas tunicata to colonize natural biofilms and its effect on microbial community structure.

Rao D, Skovhus T, Tujula N, Holmström C, Dahllöf I, Webb JS, Kjelleberg S.

FEMS Microbiol Ecol. 2010 Sep;73(3):450-7. doi: 10.1111/j.1574-6941.2010.00917.x. Epub 2010 May 25.

36.

Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic di-GMP levels, and enhanced dispersal.

Barraud N, Schleheck D, Klebensberger J, Webb JS, Hassett DJ, Rice SA, Kjelleberg S.

J Bacteriol. 2009 Dec;191(23):7333-42. doi: 10.1128/JB.00975-09. Epub 2009 Oct 2.

37.

Role of mutation in Pseudomonas aeruginosa biofilm development.

Conibear TC, Collins SL, Webb JS.

PLoS One. 2009 Jul 16;4(7):e6289. doi: 10.1371/journal.pone.0006289.

38.

Pseudomonas aeruginosa PAO1 preferentially grows as aggregates in liquid batch cultures and disperses upon starvation.

Schleheck D, Barraud N, Klebensberger J, Webb JS, McDougald D, Rice SA, Kjelleberg S.

PLoS One. 2009;4(5):e5513. doi: 10.1371/journal.pone.0005513. Epub 2009 May 13.

39.

Limiting and detecting bacterial contamination of apheresis platelets: inlet-line diversion and increased culture volume improve component safety.

Eder AF, Kennedy JM, Dy BA, Notari EP, Skeate R, Bachowski G, Mair DC, Webb JS, Wagner SJ, Dodd RY, Benjamin RJ; American Red Cross Regional Blood Centers.

Transfusion. 2009 Aug;49(8):1554-63. doi: 10.1111/j.1537-2995.2009.02192.x.

PMID:
19413735
40.

Nitric oxide-mediated dispersal in single- and multi-species biofilms of clinically and industrially relevant microorganisms.

Barraud N, Storey MV, Moore ZP, Webb JS, Rice SA, Kjelleberg S.

Microb Biotechnol. 2009 May;2(3):370-8. doi: 10.1111/j.1751-7915.2009.00098.x. Epub 2009 Mar 13.

41.

Contact-dependent growth inhibition causes reversible metabolic downregulation in Escherichia coli.

Aoki SK, Webb JS, Braaten BA, Low DA.

J Bacteriol. 2009 Mar;191(6):1777-86. doi: 10.1128/JB.01437-08. Epub 2009 Jan 5.

42.

Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lung.

Manos J, Arthur J, Rose B, Tingpej P, Fung C, Curtis M, Webb JS, Hu H, Kjelleberg S, Gorrell MD, Bye P, Harbour C.

J Med Microbiol. 2008 Dec;57(Pt 12):1454-65. doi: 10.1099/jmm.0.2008/005009-0.

PMID:
19018014
43.

The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage.

Rice SA, Tan CH, Mikkelsen PJ, Kung V, Woo J, Tay M, Hauser A, McDougald D, Webb JS, Kjelleberg S.

ISME J. 2009 Mar;3(3):271-82. doi: 10.1038/ismej.2008.109. Epub 2008 Nov 13.

44.

Marine biofilm bacteria evade eukaryotic predation by targeted chemical defense.

Matz C, Webb JS, Schupp PJ, Phang SY, Penesyan A, Egan S, Steinberg P, Kjelleberg S.

PLoS One. 2008 Jul 23;3(7):e2744. doi: 10.1371/journal.pone.0002744.

45.

Hydrogen peroxide linked to lysine oxidase activity facilitates biofilm differentiation and dispersal in several gram-negative bacteria.

Mai-Prochnow A, Lucas-Elio P, Egan S, Thomas T, Webb JS, Sanchez-Amat A, Kjelleberg S.

J Bacteriol. 2008 Aug;190(15):5493-501. doi: 10.1128/JB.00549-08. Epub 2008 May 23.

46.

Low densities of epiphytic bacteria from the marine alga Ulva australis inhibit settlement of fouling organisms.

Rao D, Webb JS, Holmström C, Case R, Low A, Steinberg P, Kjelleberg S.

Appl Environ Microbiol. 2007 Dec;73(24):7844-52. Epub 2007 Oct 26.

47.

Biofilm differentiation and dispersal in mucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

Kirov SM, Webb JS, O'may CY, Reid DW, Woo JK, Rice SA, Kjelleberg S.

Microbiology. 2007 Oct;153(Pt 10):3264-74.

PMID:
17906126
48.

ConiferEST: an integrated bioinformatics system for data reprocessing and mining of conifer expressed sequence tags (ESTs).

Liang C, Wang G, Liu L, Ji G, Fang L, Liu Y, Carter K, Webb JS, Dean JF.

BMC Genomics. 2007 May 29;8:134.

49.

WebTraceMiner: a web service for processing and mining EST sequence trace files.

Liang C, Wang G, Liu L, Ji G, Liu Y, Chen J, Webb JS, Reese G, Dean JF.

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W137-42. Epub 2007 May 8.

50.

Biofilm dispersal and exacerbations of cystic fibrosis lung disease.

Reid DW, Kirov SM, Webb JS, Carroll V, Kjelleberg S, Champion A, Sanderson K.

Pediatr Pulmonol. 2006 Dec;41(12):1254; author reply 1255. No abstract available.

PMID:
17068827

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