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Items: 20


Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila.

Syed A, Lukacsovich T, Pomeroy M, Bardwell AJ, Decker GT, Waymire KG, Purcell J, Huang W, Gui J, Padilla EM, Park C, Paul A, Pham TBT, Rodriguez Y, Wei S, Worthge S, Zebarjedi R, Zhang B, Bardwell L, Marsh JL, MacGregor GR.

Dev Biol. 2019 Jan 1;445(1):37-53. doi: 10.1016/j.ydbio.2018.10.016. Epub 2018 Oct 25.


Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.

Kokoszka JE, Waymire KG, Flierl A, Sweeney KM, Angelin A, MacGregor GR, Wallace DC.

Biochim Biophys Acta. 2016 Aug;1857(8):1203-1212. doi: 10.1016/j.bbabio.2016.03.026. Epub 2016 Apr 24.


Mouse mtDNA mutant model of Leber hereditary optic neuropathy.

Lin CS, Sharpley MS, Fan W, Waymire KG, Sadun AA, Carelli V, Ross-Cisneros FN, Baciu P, Sung E, McManus MJ, Pan BX, Gil DW, Macgregor GR, Wallace DC.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20065-70. doi: 10.1073/pnas.1217113109. Epub 2012 Nov 5.


Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts.

Fielder TJ, Yi CS, Masumi J, Waymire KG, Chen HW, Wang S, Shi KX, Wallace DC, MacGregor GR.

Transgenic Res. 2012 Dec;21(6):1149-58. doi: 10.1007/s11248-012-9605-3. Epub 2012 Mar 16.


The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2.

Navarro SJ, Trinh T, Lucas CA, Ross AJ, Waymire KG, Macgregor GR.

G3 (Bethesda). 2012 Jan;2(1):99-102. doi: 10.1534/g3.111.000778. Epub 2012 Jan 1.


A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations.

Fan W, Waymire KG, Narula N, Li P, Rocher C, Coskun PE, Vannan MA, Narula J, Macgregor GR, Wallace DC.

Science. 2008 Feb 15;319(5865):958-62. doi: 10.1126/science.1147786.


FNDC3A is required for adhesion between spermatids and Sertoli cells.

Obholz KL, Akopyan A, Waymire KG, MacGregor GR.

Dev Biol. 2006 Oct 15;298(2):498-513. Epub 2006 Jul 8.


The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore.

Kokoszka JE, Waymire KG, Levy SE, Sligh JE, Cai J, Jones DP, MacGregor GR, Wallace DC.

Nature. 2004 Jan 29;427(6973):461-5.


Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice.

Campbell PK, Waymire KG, Heier RL, Sharer C, Day DE, Reimann H, Jaje JM, Friedrich GA, Burmeister M, Bartness TJ, Russell LD, Young LJ, Zimmer M, Jenne DE, MacGregor GR.

Genetics. 2002 Sep;162(1):307-20.


Spermatogenesis in Bclw-deficient mice.

Russell LD, Warren J, Debeljuk L, Richardson LL, Mahar PL, Waymire KG, Amy SP, Ross AJ, MacGregor GR.

Biol Reprod. 2001 Jul;65(1):318-32.


The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR, Thompson CB.

Mol Cell. 2000 Dec;6(6):1389-99.


Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice.

Sligh JE, Levy SE, Waymire KG, Allard P, Dillehay DL, Nusinowitz S, Heckenlively JR, MacGregor GR, Wallace DC.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14461-6.


Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene.

Esposito LA, Kokoszka JE, Waymire KG, Cottrell B, MacGregor GR, Wallace DC.

Free Radic Biol Med. 2000 Mar 1;28(5):754-66.


Transfer of chloramphenicol-resistant mitochondrial DNA into the chimeric mouse.

Levy SE, Waymire KG, Kim YL, MacGregor GR, Wallace DC.

Transgenic Res. 1999 Apr;8(2):137-45.


Increased affiliative response to vasopressin in mice expressing the V1a receptor from a monogamous vole.

Young LJ, Nilsen R, Waymire KG, MacGregor GR, Insel TR.

Nature. 1999 Aug 19;400(6746):766-8.


Testicular degeneration in Bclw-deficient mice.

Ross AJ, Waymire KG, Moss JE, Parlow AF, Skinner MK, Russell LD, MacGregor GR.

Nat Genet. 1998 Mar;18(3):251-6.


A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator.

Graham BH, Waymire KG, Cottrell B, Trounce IA, MacGregor GR, Wallace DC.

Nat Genet. 1997 Jul;16(3):226-34.


The 5' flanking region of the monogamous prairie vole oxytocin receptor gene directs tissue-specific expression in transgenic mice.

Young LJ, Waymire KG, Nilsen R, Macgregor GR, Wang Z, Insel TR.

Ann N Y Acad Sci. 1997 Jan 15;807:514-7. No abstract available.


Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.

Waymire KG, Mahuren JD, Jaje JM, Guilarte TR, Coburn SP, MacGregor GR.

Nat Genet. 1995 Sep;11(1):45-51.


Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice.

Yokoyama T, Silversides DW, Waymire KG, Kwon BS, Takeuchi T, Overbeek PA.

Nucleic Acids Res. 1990 Dec 25;18(24):7293-8.

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