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Becoming human: human infants link language and cognition, but what about the other great apes?

Novack MA, Waxman S.

Philos Trans R Soc Lond B Biol Sci. 2020 Jan 6;375(1789):20180408. doi: 10.1098/rstb.2018.0408. Epub 2019 Nov 18.


Building sensory axons: Delivery and distribution of NaV1.7 channels and effects of inflammatory mediators.

Akin EJ, Higerd GP, Mis MA, Tanaka BS, Adi T, Liu S, Dib-Hajj FB, Waxman SG, Dib-Hajj SD.

Sci Adv. 2019 Oct 23;5(10):eaax4755. doi: 10.1126/sciadv.aax4755. eCollection 2019 Oct.


A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain.

Huang J, Estacion M, Zhao P, Dib-Hajj FB, Schulman B, Abicht A, Kurth I, Brockmann K, Waxman SG, Dib-Hajj SD.

Front Neurosci. 2019 Sep 3;13:918. doi: 10.3389/fnins.2019.00918. eCollection 2019.


Rat NaV1.7 loss-of-function genetic model: Deficient nociceptive and neuropathic pain behavior with retained olfactory function and intra-epidermal nerve fibers.

Grubinska B, Chen L, Alsaloum M, Rampal N, Matson DJ, Yang C, Taborn K, Zhang M, Youngblood B, Liu D, Galbreath E, Allred S, Lepherd M, Ferrando R, Kornecook TJ, Lehto SG, Waxman SG, Moyer BD, Dib-Hajj S, Gingras J.

Mol Pain. 2019 Jan-Dec;15:1744806919881846. doi: 10.1177/1744806919881846. No abstract available.


Measurement of axonal excitability: Consensus guidelines.

Kiernan MC, Bostock H, Park SB, Kaji R, Krarup C, Krishnan AV, Kuwabara S, Lin CS, Misawa S, Moldovan M, Sung J, Vucic S, Wainger BJ, Waxman S, Burke D.

Clin Neurophysiol. 2019 Aug 2. pii: S1388-2457(19)31170-8. doi: 10.1016/j.clinph.2019.07.023. [Epub ahead of print] Review.


Crying helps, but being sad doesn't: Infants constrain nominal reference online using known verbs, but not known adjectives.

Syrett K, LaTourrette A, Ferguson B, Waxman SR.

Cognition. 2019 Dec;193:104033. doi: 10.1016/j.cognition.2019.104033. Epub 2019 Aug 9.


Evaluation of allometric scaling as a tool for extrapolation of the enrofloxacin dose in American black vultures (Coragyps atratus).

Waxman S, Prados AP, De Lucas JJ, Wiemeyer G, Torres-Bianchini L, Andres MIS, Rodríguez C.

Am J Vet Res. 2019 Aug;80(8):727-735. doi: 10.2460/ajvr.80.8.727.


Plaque burden can be assessed using intravascular optical coherence tomography and a dedicated automated processing algorithm: a comparison study with intravascular ultrasound.

Gerbaud E, Weisz G, Tanaka A, Luu R, Osman HASH, Baldwin G, Coste P, Cognet L, Waxman S, Zheng H, Moses JW, Mintz GS, Akasaka T, Maehara A, Tearney GJ.

Eur Heart J Cardiovasc Imaging. 2019 Jul 21. pii: jez185. doi: 10.1093/ehjci/jez185. [Epub ahead of print]


Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner.

Effraim PR, Huang J, Lampert A, Stamboulian S, Zhao P, Black JA, Dib-Hajj SD, Waxman SG.

Neurobiol Pain. 2019 Mar 27;6:100029. doi: 10.1016/j.ynpai.2019.100029. eCollection 2019 Aug-Dec.


Cancer mortality in the elderly in 11 countries worldwide, 1970-2015.

Carioli G, Malvezzi M, Bertuccio P, Hashim D, Waxman S, Negri E, Boffetta P, La Vecchia C.

Ann Oncol. 2019 May 30. pii: mdz178. doi: 10.1093/annonc/mdz178. [Epub ahead of print]


NaV 1.6 regulates excitability of mechanosensitive sensory neurons.

Israel MR, Tanaka BS, Castro J, Thongyoo P, Robinson SD, Zhao P, Deuis JR, Craik DJ, Durek T, Brierley SM, Waxman SG, Dib-Hajj SD, Vetter I.

J Physiol. 2019 Jul;597(14):3751-3768. doi: 10.1113/JP278148. Epub 2019 May 13.


A gain-of-function sodium channel β2-subunit mutation in painful diabetic neuropathy.

Alsaloum M, Estacion M, Almomani R, Gerrits MM, Bönhof GJ, Ziegler D, Malik R, Ferdousi M, Lauria G, Merkies IS, Faber CG, Dib-Hajj S, Waxman SG; Propane Study Group.

Mol Pain. 2019 Jan-Dec;15:1744806919849802. doi: 10.1177/1744806919849802.


Pointer-kindreds and pain: big lessons from small families.

Waxman SG.

Pain. 2019 May;160 Suppl 1:S49-S52. doi: 10.1097/j.pain.0000000000001492.


Restoration of brain circulation and cellular functions hours post-mortem.

Vrselja Z, Daniele SG, Silbereis J, Talpo F, Morozov YM, Sousa AMM, Tanaka BS, Skarica M, Pletikos M, Kaur N, Zhuang ZW, Liu Z, Alkawadri R, Sinusas AJ, Latham SR, Waxman SG, Sestan N.

Nature. 2019 Apr;568(7752):336-343. doi: 10.1038/s41586-019-1099-1. Epub 2019 Apr 17.


Outflow facility and extent of angle closure in a porcine model.

Hong Y, Wang C, Loewen R, Waxman S, Shah P, Chen S, Esfandiari H, Loewen NA.

Graefes Arch Clin Exp Ophthalmol. 2019 Jun;257(6):1239-1245. doi: 10.1007/s00417-019-04279-1. Epub 2019 Apr 3.


Peripheral afferents and the pain experience.

Waxman SG.

Pain. 2019 Jul;160(7):1487-1488. doi: 10.1097/j.pain.0000000000001527. No abstract available.


Impact of pigment dispersion on trabecular meshwork cells.

Wang C, Dang Y, Loewen RT, Waxman S, Shah P, Xia X, Loewen NA.

Graefes Arch Clin Exp Ophthalmol. 2019 Jun;257(6):1217-1230. doi: 10.1007/s00417-019-04300-7. Epub 2019 Mar 28.


Studying the Real-Time Interpretation of Novel Noun and Verb Meanings in Young Children.

de Carvalho A, Babineau M, Trueswell JC, Waxman SR, Christophe A.

Front Psychol. 2019 Feb 18;10:274. doi: 10.3389/fpsyg.2019.00274. eCollection 2019.


The Two Sides of NaV1.7: Painful and Painless Channelopathies.

Waxman SG, Dib-Hajj SD.

Neuron. 2019 Mar 6;101(5):765-767. doi: 10.1016/j.neuron.2019.02.016.


Infants' advances in speech perception shape their earliest links between language and cognition.

Perszyk DR, Waxman SR.

Sci Rep. 2019 Mar 1;9(1):3293. doi: 10.1038/s41598-019-39511-9.


Defining the Role Of Language in Infants' Object Categorization with Eye-tracking Paradigms.

LaTourrette A, Waxman SR.

J Vis Exp. 2019 Feb 8;(144). doi: 10.3791/59291.


Alabama to Beijing… and Back: The Search for a Pain Gene.

Waxman SG.

Cerebrum. 2018 Jan 1;2018. pii: cer-02-18. eCollection 2018 Jan-Feb.


Sodium Channels in Human Pain Disorders: Genetics and Pharmacogenomics.

Dib-Hajj SD, Waxman SG.

Annu Rev Neurosci. 2019 Jul 8;42:87-106. doi: 10.1146/annurev-neuro-070918-050144. Epub 2019 Jan 31.


Bias at the intersection of race and gender: Evidence from preschool-aged children.

Perszyk DR, Lei RF, Bodenhausen GV, Richeson JA, Waxman SR.

Dev Sci. 2019 May;22(3):e12788. doi: 10.1111/desc.12788. Epub 2019 Jan 23.


The Role of Voltage-Gated Sodium Channels in Pain Signaling.

Bennett DL, Clark AJ, Huang J, Waxman SG, Dib-Hajj SD.

Physiol Rev. 2019 Apr 1;99(2):1079-1151. doi: 10.1152/physrev.00052.2017. Review.


Lacosamide in patients with Nav1.7 mutations-related small fibre neuropathy: a randomized controlled trial.

de Greef BTA, Hoeijmakers JGJ, Geerts M, Oakes M, Church TJE, Waxman SG, Dib-Hajj SD, Faber CG, Merkies ISJ.

Brain. 2019 Feb 1;142(2):263-275. doi: 10.1093/brain/awy329.


Small-fiber neuropathy: Expanding the clinical pain universe.

Sopacua M, Hoeijmakers JGJ, Merkies ISJ, Lauria G, Waxman SG, Faber CG.

J Peripher Nerv Syst. 2019 Mar;24(1):19-33. doi: 10.1111/jns.12298. Epub 2019 Jan 8. Review.


Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.

Eijkenboom I, Sopacua M, Hoeijmakers JGJ, de Greef BTA, Lindsey P, Almomani R, Marchi M, Vanoevelen J, Smeets HJM, Waxman SG, Lauria G, Merkies ISJ, Faber CG, Gerrits MM.

J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):342-352. doi: 10.1136/jnnp-2018-319042. Epub 2018 Dec 15.


Detection of local and remote cellular damage caused by spinal cord and peripheral nerve injury using a heat shock signaling reporter system.

Hashimoto-Torii K, Sasaki M, Chang YW, Hwang H, Waxman SG, Kocsis JD, Rakic P, Torii M.

IBRO Rep. 2018 Nov 6;5:91-98. doi: 10.1016/j.ibror.2018.11.003. eCollection 2018 Dec.


Resilience to Pain: A Peripheral Component Identified Using Induced Pluripotent Stem Cells and Dynamic Clamp.

Mis MA, Yang Y, Tanaka BS, Gomis-Perez C, Liu S, Dib-Hajj F, Adi T, Garcia-Milian R, Schulman BR, Dib-Hajj SD, Waxman SG.

J Neurosci. 2019 Jan 16;39(3):382-392. doi: 10.1523/JNEUROSCI.2433-18.2018. Epub 2018 Nov 20.


RKI-1447, a Rho kinase inhibitor, causes ocular hypotension, actin stress fiber disruption, and increased phagocytosis.

Dang Y, Wang C, Shah P, Waxman S, Loewen RT, Loewen NA.

Graefes Arch Clin Exp Ophthalmol. 2019 Jan;257(1):101-109. doi: 10.1007/s00417-018-4175-6. Epub 2018 Nov 19.


When veps cry: Two-year-olds efficiently learn novel words from linguistic contexts alone.

Ferguson B, Graf E, Waxman SR.

Lang Learn Dev. 2018;14(1):1-12. doi: 10.1080/15475441.2017.1311260. Epub 2017 May 12.


Pediatric Erythromelalgia and SCN9A Mutations: Systematic Review and Single-Center Case Series.

Arthur L, Keen K, Verriotis M, Peters J, Kelly A, Howard RF, Dib-Hajj SD, Waxman SG, Walker SM.

J Pediatr. 2019 Mar;206:217-224.e9. doi: 10.1016/j.jpeds.2018.10.024. Epub 2018 Nov 9.


A novel gain-of-function Nav1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy.

Adi T, Estacion M, Schulman BR, Vernino S, Dib-Hajj SD, Waxman SG.

Mol Pain. 2018 Jan-Dec;14:1744806918815007. doi: 10.1177/1744806918815007. Epub 2018 Nov 5.


Structure-Function Changes of the Porcine Distal Outflow Tract in Response to Nitric Oxide.

Waxman S, Wang C, Dang Y, Hong Y, Esfandiari H, Shah P, Lathrop KL, Loewen RT, Loewen NA.

Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):4886-4895. doi: 10.1167/iovs.18-24943.


Characterization of small fiber pathology in a mouse model of Fabry disease.

Hofmann L, Hose D, Grießhammer A, Blum R, Döring F, Dib-Hajj S, Waxman S, Sommer C, Wischmeyer E, Üçeyler N.

Elife. 2018 Oct 17;7. pii: e39300. doi: 10.7554/eLife.39300.


Expression of pathogenic SCN9A mutations in the zebrafish: A model to study small-fiber neuropathy.

Eijkenboom I, Sopacua M, Otten ABC, Gerrits MM, Hoeijmakers JGJ, Waxman SG, Lombardi R, Lauria G, Merkies ISJ, Smeets HJM, Faber CG, Vanoevelen JM; PROPANE Study Group.

Exp Neurol. 2019 Jan;311:257-264. doi: 10.1016/j.expneurol.2018.10.008. Epub 2018 Oct 11.


Nav1.5 in astrocytes plays a sex-specific role in clinical outcomes in a mouse model of multiple sclerosis.

Pappalardo LW, Samad OA, Liu S, Zwinger PJ, Black JA, Waxman SG.

Glia. 2018 Oct;66(10):2174-2187. doi: 10.1002/glia.23470. Epub 2018 Sep 8.


Somatosensory Neurons Enter a State of Altered Excitability during Hibernation.

Hoffstaetter LJ, Mastrotto M, Merriman DK, Dib-Hajj SD, Waxman SG, Bagriantsev SN, Gracheva EO.

Curr Biol. 2018 Sep 24;28(18):2998-3004.e3. doi: 10.1016/j.cub.2018.07.020. Epub 2018 Aug 30.


A little labeling goes a long way: Semi-supervised learning in infancy.

LaTourrette A, Waxman SR.

Dev Sci. 2019 Jan;22(1):e12736. doi: 10.1111/desc.12736. Epub 2018 Sep 18.


The Novel Activity of Carbamazepine as an Activation Modulator Extends from NaV1.7 Mutations to the NaV1.8-S242T Mutant Channel from a Patient with Painful Diabetic Neuropathy.

Han C, Themistocleous AC, Estacion M, Dib-Hajj FB, Blesneac I, Macala L, Fratter C, Bennett DL, Waxman SG, Dib-Hajj SD.

Mol Pharmacol. 2018 Nov;94(5):1256-1269. doi: 10.1124/mol.118.113076. Epub 2018 Aug 22.


Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits.

Dash B, Dib-Hajj SD, Waxman SG.

Mol Brain. 2018 Aug 7;11(1):45. doi: 10.1186/s13041-018-0388-1.


Loss-of-function mutations of SCN10A encoding NaV1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease.

Nettuwakul C, Praditsap O, Sawasdee N, Rungroj N, Ruamyod K, Watanapa WB, Junking M, Sangnual S, Sritippayawan S, Cheunsuchon B, Chuawattana D, Rojsatapong S, Chaowagul W, Dib-Hajj SD, Waxman SG, Yenchitsomanus PT.

Sci Rep. 2018 Jul 11;8(1):10453. doi: 10.1038/s41598-018-28623-3.


Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells.

Wang R, Li Y, Gong P, Gabrilove J, Waxman S, Jing Y.

Mol Cancer Ther. 2018 Sep;17(9):1871-1880. doi: 10.1158/1535-7163.MCT-17-0298. Epub 2018 Jun 29.


Therapeutic potential of Pak1 inhibition for pain associated with cutaneous burn injury.

Guo Y, Benson C, Hill M, Henry S, Effraim P, Waxman SG, Dib-Hajj S, Tan AM.

Mol Pain. 2018 Jan-Dec;14:1744806918788648. doi: 10.1177/1744806918788648. Epub 2018 Jun 29.


Nonmuscle myosin II isoforms interact with sodium channel alpha subunits.

Dash B, Han C, Waxman SG, Dib-Hajj SD.

Mol Pain. 2018 Jan-Dec;14:1744806918788638. doi: 10.1177/1744806918788638. Epub 2018 Jun 29.


Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons.

Mis MA, Rogers MF, Jeffries AR, Wilbrey AL, Chen L, Yang Y, Dib-Hajj S, Waxman SG, Stevens EB, Randall AD.

Aging Cell. 2018 Aug;17(4):e12795. doi: 10.1111/acel.12795. Epub 2018 Jun 25.


High-Resolution, Three-Dimensional Reconstruction of the Outflow Tract Demonstrates Segmental Differences in Cleared Eyes.

Waxman S, Loewen RT, Dang Y, Watkins SC, Watson AM, Loewen NA.

Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2371-2380. doi: 10.1167/iovs.17-23075.


Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner.

Li Y, Zhu T, Yang H, Dib-Hajj SD, Waxman SG, Yu Y, Xu TL, Cheng X.

Mol Pain. 2018 Jan-Dec;14:1744806918782229. doi: 10.1177/1744806918782229. Epub 2018 May 23.


Intraocular pressure elevation precedes a phagocytosis decline in a model of pigmentary glaucoma.

Dang Y, Waxman S, Wang C, Shah P, Loewen RT, Loewen NA.

Version 2. F1000Res. 2018 Feb 12 [revised 2018 Jan 1];7:174. doi: 10.12688/f1000research.13797.2. eCollection 2018.

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