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Items: 32


Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018 Jun;2(6):443-452. doi: 10.1038/s41551-018-0231-0. Epub 2018 Apr 23.


Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses.

Yamane D, Feng H, Rivera-Serrano EE, Selitsky SR, Hirai-Yuki A, Das A, McKnight KL, Misumi I, Hensley L, Lovell W, González-López O, Suzuki R, Matsuda M, Nakanishi H, Ohto-Nakanishi T, Hishiki T, Wauthier E, Oikawa T, Morita K, Reid LM, Sethupathy P, Kohara M, Whitmire JK, Lemon SM.

Nat Microbiol. 2019 Jul;4(7):1096-1104. doi: 10.1038/s41564-019-0425-6. Epub 2019 Apr 15.


MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma.

Dinh TA, Jewell ML, Kanke M, Francisco A, Sritharan R, Turnham RE, Lee S, Kastenhuber ER, Wauthier E, Guy CD, Yeung RS, Lowe SW, Reid LM, Scott JD, Diehl AM, Sethupathy P.

Cell Mol Gastroenterol Hepatol. 2019;7(4):803-817. doi: 10.1016/j.jcmgh.2019.01.008. Epub 2019 Feb 11.


Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018;2:443-452. Epub 2018 Apr 23.


NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.

Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM.

Nat Immunol. 2017 Dec;18(12):1299-1309. doi: 10.1038/ni.3853. Epub 2017 Oct 2.


Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma.

Dinh TA, Vitucci EC, Wauthier E, Graham RP, Pitman WA, Oikawa T, Chen M, Silva GO, Greene KG, Torbenson MS, Reid LM, Sethupathy P.

Sci Rep. 2017 Mar 17;7:44653. doi: 10.1038/srep44653.


Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells.

Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM.

Nat Commun. 2015 Oct 6;6:8070. doi: 10.1038/ncomms9070.


Identification of microRNAs specific for epithelial cell adhesion molecule-positive tumor cells in hepatocellular carcinoma.

Ji J, Zheng X, Forgues M, Yamashita T, Wauthier EL, Reid LM, Wen X, Song Y, Wei JS, Khan J, Thorgeirsson SS, Wang XW.

Hepatology. 2015 Sep;62(3):829-40. doi: 10.1002/hep.27886. Epub 2015 Jun 30.


Lineage-dependent effects of aryl hydrocarbon receptor agonists contribute to liver tumorigenesis.

Harrill JA, Parks BB, Wauthier E, Rowlands JC, Reid LM, Thomas RS.

Hepatology. 2015 Feb;61(2):548-60. doi: 10.1002/hep.27547. Epub 2015 Jan 5.


Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.

Yamane D, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, Oikawa T, Whitmire JK, Heise MT, Dittmer DP, Kao CC, Pitson SM, Merrill AH Jr, Reid LM, Lemon SM.

Nat Med. 2014 Aug;20(8):927-35. doi: 10.1038/nm.3610. Epub 2014 Jul 27.


Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis.

Wang Y, Lanzoni G, Carpino G, Cui CB, Dominguez-Bendala J, Wauthier E, Cardinale V, Oikawa T, Pileggi A, Gerber D, Furth ME, Alvaro D, Gaudio E, Inverardi L, Reid LM.

Stem Cells. 2013 Sep;31(9):1966-79. doi: 10.1002/stem.1460.


Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers.

Oikawa T, Kamiya A, Zeniya M, Chikada H, Hyuck AD, Yamazaki Y, Wauthier E, Tajiri H, Miller LD, Wang XW, Reid LM, Nakauchi H.

Hepatology. 2013 Apr;57(4):1469-83. doi: 10.1002/hep.26159. Epub 2013 Mar 6.


Successful transplantation of human hepatic stem cells with restricted localization to liver using hyaluronan grafts.

Turner RA, Wauthier E, Lozoya O, McClelland R, Bowsher JE, Barbier C, Prestwich G, Hsu E, Gerber DA, Reid LM.

Hepatology. 2013 Feb;57(2):775-84. doi: 10.1002/hep.26065. Epub 2013 Jan 10.


Hyaluronan-supplemented buffers preserve adhesion mechanisms facilitating cryopreservation of human hepatic stem/progenitor cells.

Turner RA, Mendel G, Wauthier E, Barbier C, Reid LM.

Cell Transplant. 2012;21(10):2257-66. doi: 10.3727/096368912X637000. Epub 2012 Apr 2.


Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets.

Cardinale V, Wang Y, Carpino G, Cui CB, Gatto M, Rossi M, Berloco PB, Cantafora A, Wauthier E, Furth ME, Inverardi L, Dominguez-Bendala J, Ricordi C, Gerber D, Gaudio E, Alvaro D, Reid L.

Hepatology. 2011 Dec;54(6):2159-72. doi: 10.1002/hep.24590.


Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche.

Lozoya OA, Wauthier E, Turner RA, Barbier C, Prestwich GD, Guilak F, Superfine R, Lubkin SR, Reid LM.

Biomaterials. 2011 Oct;32(30):7389-402. doi: 10.1016/j.biomaterials.2011.06.042. Epub 2011 Jul 23.


Human hepatic stem cell and maturational liver lineage biology.

Turner R, Lozoya O, Wang Y, Cardinale V, Gaudio E, Alpini G, Mendel G, Wauthier E, Barbier C, Alvaro D, Reid LM.

Hepatology. 2011 Mar;53(3):1035-45. doi: 10.1002/hep.24157. Review.


Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds.

Wang Y, Cui CB, Yamauchi M, Miguez P, Roach M, Malavarca R, Costello MJ, Cardinale V, Wauthier E, Barbier C, Gerber DA, Alvaro D, Reid LM.

Hepatology. 2011 Jan;53(1):293-305. doi: 10.1002/hep.24012. Epub 2010 Dec 13.


In situ labeling and magnetic resonance imaging of transplanted human hepatic stem cells.

McClelland R, Wauthier E, Tallheden T, Reid LM, Hsu E.

Mol Imaging Biol. 2011 Oct;13(5):911-22. doi: 10.1007/s11307-010-0422-x.


Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates.

Wang Y, Yao HL, Cui CB, Wauthier E, Barbier C, Costello MJ, Moss N, Yamauchi M, Sricholpech M, Gerber D, Loboa EG, Reid LM.

Hepatology. 2010 Oct;52(4):1443-54. doi: 10.1002/hep.23829.


Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells.

Ji J, Yamashita T, Budhu A, Forgues M, Jia HL, Li C, Deng C, Wauthier E, Reid LM, Ye QH, Qin LX, Yang W, Wang HY, Tang ZY, Croce CM, Wang XW.

Hepatology. 2009 Aug;50(2):472-80. doi: 10.1002/hep.22989.


EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features.

Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, Jia H, Ye Q, Qin LX, Wauthier E, Reid LM, Minato H, Honda M, Kaneko S, Tang ZY, Wang XW.

Gastroenterology. 2009 Mar;136(3):1012-24. doi: 10.1053/j.gastro.2008.12.004. Epub 2008 Dec 6.


Ex vivo conditions for self-replication of human hepatic stem cells.

McClelland R, Wauthier E, Zhang L, Melhem A, Schmelzer E, Barbier C, Reid LM.

Tissue Eng Part C Methods. 2008 Dec;14(4):341-51. doi: 10.1089/ten.tec.2008.0073.


Hepatic stem cells and hepatoblasts: identification, isolation, and ex vivo maintenance.

Wauthier E, Schmelzer E, Turner W, Zhang L, LeCluyse E, Ruiz J, Turner R, Furth ME, Kubota H, Lozoya O, Barbier C, McClelland R, Yao HL, Moss N, Bruce A, Ludlow J, Reid LM.

Methods Cell Biol. 2008;86:137-225. doi: 10.1016/S0091-679X(08)00008-3. No abstract available.


Gradients in the liver's extracellular matrix chemistry from periportal to pericentral zones: influence on human hepatic progenitors.

McClelland R, Wauthier E, Uronis J, Reid L.

Tissue Eng Part A. 2008 Jan;14(1):59-70. doi: 10.1089/ten.a.2007.0058.


Mature human hepatocytes from ex vivo differentiation of alginate-encapsulated hepatoblasts.

Cheng N, Wauthier E, Reid LM.

Tissue Eng Part A. 2008 Jan;14(1):1-7. doi: 10.1089/ten.a.2007.0131.


Human hepatic stem cells from fetal and postnatal donors.

Schmelzer E, Zhang L, Bruce A, Wauthier E, Ludlow J, Yao HL, Moss N, Melhem A, McClelland R, Turner W, Kulik M, Sherwood S, Tallheden T, Cheng N, Furth ME, Reid LM.

J Exp Med. 2007 Aug 6;204(8):1973-87. Epub 2007 Jul 30.


Human hepatoblast phenotype maintained by hyaluronan hydrogels.

Turner WS, Schmelzer E, McClelland R, Wauthier E, Chen W, Reid LM.

J Biomed Mater Res B Appl Biomater. 2007 Jul;82(1):156-68.


The phenotypes of pluripotent human hepatic progenitors.

Schmelzer E, Wauthier E, Reid LM.

Stem Cells. 2006 Aug;24(8):1852-8. Epub 2006 Apr 20.


Differential repair and replication of damaged DNA in ribosomal RNA genes in different CHO cell lines.

Wauthier EL, Hanawalt PC, Vos JM.

J Cell Biochem. 1990 Jun;43(2):173-83.


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