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Items: 44

1.

Tuning the in vitro sensing and signaling properties of cyanobacterial PII protein by mutation of key residues.

Selim KA, Haffner M, Watzer B, Forchhammer K.

Sci Rep. 2019 Dec 12;9(1):18985. doi: 10.1038/s41598-019-55495-y.

PMID:
31831819
2.

The Signal Transduction Protein PII Controls Ammonium, Nitrate and Urea Uptake in Cyanobacteria.

Watzer B, Spät P, Neumann N, Koch M, Sobotka R, Macek B, Hennrich O, Forchhammer K.

Front Microbiol. 2019 Jun 25;10:1428. doi: 10.3389/fmicb.2019.01428. eCollection 2019.

3.

Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment.

Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R.

Mol Oncol. 2019 Feb;13(2):185-201. doi: 10.1002/1878-0261.12396. Epub 2018 Nov 15.

4.

Cyanophycin Synthesis Optimizes Nitrogen Utilization in the Unicellular Cyanobacterium Synechocystis sp. Strain PCC 6803.

Watzer B, Forchhammer K.

Appl Environ Microbiol. 2018 Oct 1;84(20). pii: e01298-18. doi: 10.1128/AEM.01298-18. Print 2018 Oct 15.

5.

PII Protein-Derived FRET Sensors for Quantification and Live-Cell Imaging of 2-Oxoglutarate.

Lüddecke J, Francois L, Spät P, Watzer B, Chilczuk T, Poschet G, Hell R, Radlwimmer B, Forchhammer K.

Sci Rep. 2017 May 3;7(1):1437. doi: 10.1038/s41598-017-01440-w.

6.

Microbiology Comment.

Forchhammer K, Watzer B.

Microbiology. 2016 May;162(5):727-729. doi: 10.1099/mic.0.000260. Epub 2016 Feb 24. No abstract available.

PMID:
26916638
7.

Metabolic pathway engineering using the central signal processor PII.

Watzer B, Engelbrecht A, Hauf W, Stahl M, Maldener I, Forchhammer K.

Microb Cell Fact. 2015 Nov 25;14:192. doi: 10.1186/s12934-015-0384-4.

8.

Photoautotrophic Polyhydroxybutyrate Granule Formation Is Regulated by Cyanobacterial Phasin PhaP in Synechocystis sp. Strain PCC 6803.

Hauf W, Watzer B, Roos N, Klotz A, Forchhammer K.

Appl Environ Microbiol. 2015 Jul;81(13):4411-22. doi: 10.1128/AEM.00604-15. Epub 2015 Apr 24.

9.

Abortion after deliberate Arthrotec® addition to food. Mass spectrometric detection of diclofenac, misoprostol acid, and their urinary metabolites.

Watzer B, Lusthof KJ, Schweer H.

Int J Legal Med. 2015 Jul;129(4):759-69. doi: 10.1007/s00414-014-1136-4. Epub 2014 Dec 19.

PMID:
25524762
10.

Phenotypic redifferentiation and cell cluster formation of cultured human articular chondrocytes in a three-dimensional oriented gelatin scaffold in the presence of PGE2--first results of a pilot study.

Brochhausen C, Sánchez N, Halstenberg S, Zehbe R, Watzer B, Schmitt VH, Hofmann A, Meurer A, Unger RE, Kirkpatrick CJ.

J Biomed Mater Res A. 2013 Aug;101(8):2374-82. doi: 10.1002/jbm.a.34538. Epub 2013 Feb 1.

PMID:
23377957
11.

Glycaemic variability in paediatric patients with type 1 diabetes on continuous subcutaneous insulin infusion (CSII) or multiple daily injections (MDI): a cross-sectional cohort study.

Schreiver C, Jacoby U, Watzer B, Thomas A, Haffner D, Fischer DC.

Clin Endocrinol (Oxf). 2013 Nov;79(5):641-7. doi: 10.1111/cen.12093. Epub 2013 Apr 19.

PMID:
23134485
12.

Mutations in the prostaglandin transporter SLCO2A1 cause primary hypertrophic osteoarthropathy with digital clubbing.

Busch J, Frank V, Bachmann N, Otsuka A, Oji V, Metze D, Shah K, Danda S, Watzer B, Traupe H, Bolz HJ, Kabashima K, Bergmann C.

J Invest Dermatol. 2012 Oct;132(10):2473-2476. doi: 10.1038/jid.2012.146. Epub 2012 Jun 14. No abstract available.

13.

Novel bioactive metabolites of dipyrone (metamizol).

Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, Cascio MG, Bisogno T, Di Marzo V, Nüsing R, Imming P.

Bioorg Med Chem. 2012 Jan 1;20(1):101-7. doi: 10.1016/j.bmc.2011.11.028. Epub 2011 Nov 25.

14.

Ozone induces synthesis of systemic prostacyclin by cyclooxygenase-2 dependent mechanism in vivo.

Schulz S, Ninke S, Watzer B, Nüsing RM.

Biochem Pharmacol. 2012 Feb 15;83(4):506-13. doi: 10.1016/j.bcp.2011.11.025. Epub 2011 Dec 2.

PMID:
22155309
15.

Effect of bacterial vaginosis on the pharmacokinetics of misoprostol in early pregnancy.

Sioutas A, Sandström A, Fiala C, Watzer B, Schweer H, Gemzell-Danielsson K.

Hum Reprod. 2012 Feb;27(2):388-93. doi: 10.1093/humrep/der407. Epub 2011 Nov 28.

PMID:
22128294
16.

A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid.

Lee VC, Yung SS, Li RH, Watzer B, Schweer H, Ng EH, Ho PC.

Hum Reprod. 2011 Nov;26(11):2981-7. doi: 10.1093/humrep/der303. Epub 2011 Sep 9.

PMID:
21908466
17.

Effect of n-3 fatty acid supplementation on urinary risk factors for calcium oxalate stone formation.

Siener R, Jansen B, Watzer B, Hesse A.

J Urol. 2011 Feb;185(2):719-24. doi: 10.1016/j.juro.2010.09.074. Epub 2010 Dec 18.

PMID:
21168878
18.

Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production.

Riederer M, Ojala PJ, Hrzenjak A, Graier WF, Malli R, Tritscher M, Hermansson M, Watzer B, Schweer H, Desoye G, Heinemann A, Frank S.

J Lipid Res. 2010 Oct;51(10):2957-66. doi: 10.1194/jlr.M006536. Epub 2010 Jul 7. Erratum in: J Lipid Res. 2011 Jan;52(1):185. Graier, Wolfgang F [added]; Malli, Roland [added].

19.

The effect of the pro-inflammatory cytokine tumor necrosis factor-alpha on human joint capsule myofibroblasts.

Mattyasovszky SG, Hofmann A, Brochhausen C, Ritz U, Kuhn S, Wollstädter J, Schulze-Koops H, Müller LP, Watzer B, Rommens PM.

Arthritis Res Ther. 2010;12(1):R4. doi: 10.1186/ar2902. Epub 2010 Jan 8.

20.

15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist.

Naruhn S, Meissner W, Adhikary T, Kaddatz K, Klein T, Watzer B, Müller-Brüsselbach S, Müller R.

Mol Pharmacol. 2010 Feb;77(2):171-84. doi: 10.1124/mol.109.060541. Epub 2009 Nov 10.

PMID:
19903832
21.

[Tissue engineering of cartilage and bone : growth factors and signaling molecules].

Brochhausen C, Lehmann M, Zehbe R, Watzer B, Grad S, Meurer A, Kirkpatrick CJ.

Orthopade. 2009 Nov;38(11):1053-62. doi: 10.1007/s00132-009-1496-5. German.

PMID:
19851750
22.

Parecoxib does not suppress thromboxane synthesis in newborn piglets with group B streptococcal sepsis.

Nögel SC, Chada M, Schmidt AM, Bosselmann S, Kandler M, Schweer H, Watzer B, Schneider H, Gessner A, Rascher W.

Prostaglandins Other Lipid Mediat. 2009 Nov;90(1-2):7-12. doi: 10.1016/j.prostaglandins.2009.06.003. Epub 2009 Jun 13.

PMID:
19527795
23.

Stability of prostaglandin E(2) (PGE (2)) embedded in poly-D,L: -lactide-co-glycolide microspheres: a pre-conditioning approach for tissue engineering applications.

Watzer B, Zehbe R, Halstenberg S, James Kirkpatrick C, Brochhausen C.

J Mater Sci Mater Med. 2009 Jun;20(6):1357-65. doi: 10.1007/s10856-008-3678-9. Epub 2009 Jan 22.

PMID:
19160024
24.

New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide.

Sinning C, Watzer B, Coste O, Nüsing RM, Ott I, Ligresti A, Di Marzo V, Imming P.

J Med Chem. 2008 Dec 25;51(24):7800-5. doi: 10.1021/jm800807k.

PMID:
19053765
25.

Dopamides, vanillylamides, ethanolamides, and arachidonic acid amides of anti-inflammatory and analgesic drug substances as TRPV1 ligands.

Sinning C, Watzer B, De Petrocellis L, Di Marzo V, Imming P.

ChemMedChem. 2008 Dec;3(12):1956-64. doi: 10.1002/cmdc.200800271.

PMID:
19003845
26.

Immobilization and controlled release of prostaglandin E2 from poly-L-lactide-co-glycolide microspheres.

Brochhausen C, Zehbe R, Watzer B, Halstenberg S, Gabler F, Schubert H, Kirkpatrick CJ.

J Biomed Mater Res A. 2009 Nov;91(2):454-62. doi: 10.1002/jbm.a.32215.

PMID:
18985760
27.

Effects of selective COX-2 inhibition on prostanoids and platelet physiology in young healthy volunteers.

Graff J, Skarke C, Klinkhardt U, Watzer B, Harder S, Seyberth H, Geisslinger G, Nüsing RM.

J Thromb Haemost. 2007 Dec;5(12):2376-85. Epub 2007 Oct 3.

28.

Pharmacokinetic profiles up to 12 h after administration of vaginal, sublingual and slow-release oral misoprostol.

Aronsson A, Fiala C, Stephansson O, Granath F, Watzer B, Schweer H, Gemzell-Danielsson K.

Hum Reprod. 2007 Jul;22(7):1912-8. Epub 2007 May 8.

PMID:
17488782
29.

Determination of chamazulene carboxylic acid in serum by high-performance liquid chromatography. Development and validation.

Ramadan M, Watzer B.

J Chromatogr A. 2006 Nov 10;1133(1-2):221-5. Epub 2006 Aug 30.

PMID:
16942774
30.

Chamazulene carboxylic acid and matricin: a natural profen and its natural prodrug, identified through similarity to synthetic drug substances.

Ramadan M, Goeters S, Watzer B, Krause E, Lohmann K, Bauer R, Hempel B, Imming P.

J Nat Prod. 2006 Jul;69(7):1041-5.

PMID:
16872141
31.

Pharmacokinetics of a novel oral slow-release form of misoprostol.

Fiala C, Aronsson A, Granath F, Stephansson O, Seyberth HW, Watzer B, Gemzell-Danielsson K.

Hum Reprod. 2005 Dec;20(12):3414-8. Epub 2005 Jul 29.

PMID:
16055461
32.

Misoprostol versus methylergometrine: pharmacokinetics in human milk.

Vogel D, Burkhardt T, Rentsch K, Schweer H, Watzer B, Zimmermann R, Von Mandach U.

Am J Obstet Gynecol. 2004 Dec;191(6):2168-73.

PMID:
15592308
33.

The pharmacokinetics of the prostaglandin E1 analogue misoprostol in plasma and colostrum after postpartum oral administration.

Abdel-Aleem H, Villar J, Gülmezoglu AM, Mostafa SA, Youssef AA, Shokry M, Watzer B.

Eur J Obstet Gynecol Reprod Biol. 2003 May 1;108(1):25-8.

PMID:
12694965
34.

Low-dose aspirin in pregnancy: maternal and neonatal aspirin concentrations and neonatal prostanoid formation.

Leonhardt A, Bernert S, Watzer B, Schmitz-Ziegler G, Seyberth HW.

Pediatrics. 2003 Jan;111(1):e77-81.

PMID:
12509599
35.
36.

Role of cyclooxygenase-2 in hyperprostaglandin E syndrome/antenatal Bartter syndrome.

Reinalter SC, Jeck N, Brochhausen C, Watzer B, Nüsing RM, Seyberth HW, Kömhoff M.

Kidney Int. 2002 Jul;62(1):253-60.

37.

Effect of preterm formula with and without long-chain polyunsaturated fatty acids on the urinary excretion of F2-isoprostanes and 8-epi-prostaglandin F2alpha.

Stier C, Schweer H, Jelinek J, Watzer B, Seyberth HW, Leonhardt A.

J Pediatr Gastroenterol Nutr. 2001 Feb;32(2):137-41.

PMID:
11321381
38.

Determination of free and glucuronide conjugated 20-hydroxyarachidonic acid (20-HETE) in urine by gas chromatography/negative ion chemical ionization mass spectrometry.

Watzer B, Reinalter S, Seyberth HW, Schweer H.

Prostaglandins Leukot Essent Fatty Acids. 2000 Mar;62(3):175-81.

PMID:
10841040
39.

Neonatal urinary prostanoid excretion.

Hoch B, Bernhard M, Seyberth HW, Watzer B, Schweer H.

Prostaglandins Other Lipid Mediat. 2000 Jan;60(1-3):9-14.

PMID:
10680771
41.

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