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Items: 1 to 50 of 477

1.

The role of keratins in modulating carcinogenesis via communication with cells of the immune system.

Sequeira I, Watt FM.

Cell Stress. 2019 Mar 23;3(4):136-138. doi: 10.15698/cst2019.04.184.

2.

Obstetric and neonatal outcomes of clozapine exposure in pregnancy: a consecutive case series.

Nguyen T, Mordecai J, Watt F, Frayne J.

Arch Womens Ment Health. 2019 Jun 15. doi: 10.1007/s00737-019-00985-1. [Epub ahead of print]

PMID:
31203441
3.

Mechanisms, Hallmarks, and Implications of Stem Cell Quiescence.

Cho IJ, Lui PP, Obajdin J, Riccio F, Stroukov W, Willis TL, Spagnoli F, Watt FM.

Stem Cell Reports. 2019 Jun 11;12(6):1190-1200. doi: 10.1016/j.stemcr.2019.05.012. Review.

4.

Mutant Lef1 controls Gata6 in sebaceous gland development and cancer.

Oulès B, Rognoni E, Hoste E, Goss G, Fiehler R, Natsuga K, Quist S, Mentink R, Donati G, Watt FM.

EMBO J. 2019 May 2;38(9). pii: e100526. doi: 10.15252/embj.2018100526. Epub 2019 Mar 18.

5.

Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.

Tziotzios C, Petridis C, Dand N, Ainali C, Saklatvala JR, Pullabhatla V, Onoufriadis A, Pramanik R, Baudry D, Lee SH, Wood K, Liu L, Seegobin S, Michelotti GA, Lwin SM, Christou EAA, Curtis CJ, de Rinaldis E, Saxena A, Holmes S, Harries M, Palamaras I, Cunningham F, Parkins G, Kaur M, Farrant P, McDonagh A, Messenger A, Jones J, Jolliffe V, Ali I, Ardern-Jones M, Mitchell C, Burrows N, Atkar R, Banfield C, Alexandroff A, Champagne C, Cooper HL, Vañó-Galván S, Molina-Ruiz AM, Perez NO, Patel GK, Macbeth A, Page M, Bryden A, Mowbray M, Wahie S, Armstrong K, Cooke N, Goodfield M, Man I, de Berker D, Dunnill G, Takwale A, Rao A, Siah TW, Sinclair R, Wade MS, Dlova NC, Setterfield J, Lewis F, Bhargava K, Kirkpatrick N, Estivill X, Stefanato CM, Flohr C, Spector T, Watt FM, Smith CH, Barker JN, Fenton DA, Simpson MA, McGrath JA.

Nat Commun. 2019 Mar 8;10(1):1150. doi: 10.1038/s41467-019-09117-w.

6.

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.

Vigilante A, Laddach A, Moens N, Meleckyte R, Leha A, Ghahramani A, Culley OJ, Kathuria A, Hurling C, Vickers A, Wiseman E, Tewary M, Zandstra PW; HipSci Consortium, Durbin R, Fraternali F, Stegle O, Birney E, Luscombe NM, Danovi D, Watt FM.

Cell Rep. 2019 Feb 19;26(8):2078-2087.e3. doi: 10.1016/j.celrep.2019.01.094.

7.

Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness.

Mobasseri SA, Zijl S, Salameti V, Walko G, Stannard A, Garcia-Manyes S, Watt FM.

Acta Biomater. 2019 Mar 15;87:256-264. doi: 10.1016/j.actbio.2019.01.063. Epub 2019 Jan 30.

8.

Micro-scaled topographies direct differentiation of human epidermal stem cells.

Zijl S, Vasilevich AS, Viswanathan P, Helling AL, Beijer NRM, Walko G, Chiappini C, de Boer J, Watt FM.

Acta Biomater. 2019 Jan 15;84:133-145. doi: 10.1016/j.actbio.2018.12.003. Epub 2018 Dec 5.

9.

Hair follicle epidermal stem cells define a niche for tactile sensation.

Cheng CC, Tsutsui K, Taguchi T, Sanzen N, Nakagawa A, Kakiguchi K, Yonemura S, Tanegashima C, Keeley SD, Kiyonari H, Furuta Y, Tomono Y, Watt FM, Fujiwara H.

Elife. 2018 Oct 25;7. pii: e38883. doi: 10.7554/eLife.38883.

10.

Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro.

Schweiger PJ, Clement DL, Page ME, Schepeler T, Zou X, Sirokmány G, Watt FM, Jensen KB.

Sci Rep. 2018 Oct 15;8(1):15255. doi: 10.1038/s41598-018-33578-6.

11.

Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management.

Marshall M, Watt FE, Vincent TL, Dziedzic K.

Nat Rev Rheumatol. 2018 Nov;14(11):641-656. doi: 10.1038/s41584-018-0095-4. Review.

PMID:
30305701
12.

Dynamic Culture Substrates That Mimic the Topography of the Epidermal-Dermal Junction.

Helling AL, Viswanathan P, Cheliotis KS, Mobasseri SA, Yang Y, El Haj AJ, Watt FM.

Tissue Eng Part A. 2019 Feb;25(3-4):214-223. doi: 10.1089/ten.TEA.2018.0125. Epub 2018 Dec 28.

13.

Fibroblast state switching orchestrates dermal maturation and wound healing.

Rognoni E, Pisco AO, Hiratsuka T, Sipilä KH, Belmonte JM, Mobasseri SA, Philippeos C, Dilão R, Watt FM.

Mol Syst Biol. 2018 Aug 29;14(8):e8174. doi: 10.15252/msb.20178174.

14.

The reward of great collaborations.

Watt FM.

Nat Cell Biol. 2018 Sep;20(9):1011. doi: 10.1038/s41556-018-0157-5. No abstract available.

PMID:
30154564
15.

Immunomodulatory role of Keratin 76 in oral and gastric cancer.

Sequeira I, Neves JF, Carrero D, Peng Q, Palasz N, Liakath-Ali K, Lord GM, Morgan PR, Lombardi G, Watt FM.

Nat Commun. 2018 Aug 24;9(1):3437. doi: 10.1038/s41467-018-05872-4.

16.

Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury.

Watt FE, Corp N, Kingsbury SR, Frobell R, Englund M, Felson DT, Levesque M, Majumdar S, Wilson C, Beard DJ, Lohmander LS, Kraus VB, Roemer F, Conaghan PG, Mason DJ; Arthritis Research UK Osteoarthritis and Crystal Disease Clinical Study Group Expert Working Group.

Osteoarthritis Cartilage. 2019 Jan;27(1):23-33. doi: 10.1016/j.joca.2018.08.001. Epub 2018 Aug 18.

17.

Bench to bedside: Current advances in regenerative medicine.

Clarke G, Harley P, Hubber EL, Manea T, Manuelli L, Read E, Watt FM.

Curr Opin Cell Biol. 2018 Dec;55:59-66. doi: 10.1016/j.ceb.2018.05.006. Epub 2018 Jul 11. Review.

PMID:
30007127
18.

Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation.

Kober KI, Cano A, Géraud C, Sipilä K, Mobasseri SA, Philippeos C, Pisco AO, Stannard A, Martin A, Salvador F, Santos V, Boutros M, Rognoni E, Watt FM.

PLoS One. 2018 Jun 28;13(6):e0199679. doi: 10.1371/journal.pone.0199679. eCollection 2018.

19.

Making the most of the waiting room: Electronic patient engagement, a mixed methods study.

Coathup V, Finlay T, Teare HJ, Kaye J, South M, Watt FE, Luqmani R.

Digit Health. 2018 Jan 10;4:2055207617751304. doi: 10.1177/2055207617751304. eCollection 2018 Jan-Dec.

20.

Homeostasis, regeneration and tumour formation in the mammalian epidermis.

Belokhvostova D, Berzanskyte I, Cujba AM, Jowett G, Marshall L, Prueller J, Watt FM.

Int J Dev Biol. 2018;62(6-7-8):571-582. doi: 10.1387/ijdb.170341fw. Review.

21.

Skin Cell Heterogeneity in Development, Wound Healing, and Cancer.

Rognoni E, Watt FM.

Trends Cell Biol. 2018 Sep;28(9):709-722. doi: 10.1016/j.tcb.2018.05.002. Epub 2018 May 25. Review.

22.

Diverse mechanisms for endogenous regeneration and repair in mammalian organs.

Wells JM, Watt FM.

Nature. 2018 May;557(7705):322-328. doi: 10.1038/s41586-018-0073-7. Epub 2018 May 16. Review.

PMID:
29769669
23.

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.

Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM.

Nature. 2018 Apr;556(7701):376-380. doi: 10.1038/s41586-018-0032-3. Epub 2018 Apr 11.

PMID:
29643507
24.

(More) women in science.

Watt FM.

Nat Rev Mol Cell Biol. 2018 Jul;19(7):413-414. doi: 10.1038/s41580-018-0006-1. No abstract available.

PMID:
29599526
25.

Myosin 10 is involved in murine pigmentation.

Liakath-Ali K, Vancollie VE, Sequeira I, Lelliott CJ, Watt FM.

Exp Dermatol. 2019 Apr;28(4):391-394. doi: 10.1111/exd.13528. Epub 2018 Apr 24.

26.

Defining Adult Stem Cells by Function, not by Phenotype.

Clevers H, Watt FM.

Annu Rev Biochem. 2018 Jun 20;87:1015-1027. doi: 10.1146/annurev-biochem-062917-012341. Epub 2018 Mar 1. Review.

PMID:
29494240
27.

Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial.

Kingsbury SR, Tharmanathan P, Keding A, Ronaldson SJ, Grainger A, Wakefield RJ, Arundel C, Birrell F, Doherty M, Vincent T, Watt FE, Dziedzic K, O'Neill TW, Arden NK, Scott DL, Dickson J, Garrood T, Green M, Menon A, Sheeran T, Torgerson D, Conaghan PG.

Ann Intern Med. 2018 Mar 20;168(6):385-395. doi: 10.7326/M17-1430. Epub 2018 Feb 20.

28.

Musculoskeletal pain and menopause.

Watt FE.

Post Reprod Health. 2018 Mar;24(1):34-43. doi: 10.1177/2053369118757537. Epub 2018 Feb 7. Review.

PMID:
29412042
29.

Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.

Philippeos C, Telerman SB, Oulès B, Pisco AO, Shaw TJ, Elgueta R, Lombardi G, Driskell RR, Soldin M, Lynch MD, Watt FM.

J Invest Dermatol. 2018 Apr;138(4):811-825. doi: 10.1016/j.jid.2018.01.016. Epub 2018 Jan 31.

30.

Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells.

Ghahramani A, Donati G, Luscombe NM, Watt FM.

Genome Biol. 2018 Jan 15;19(1):3. doi: 10.1186/s13059-017-1384-y.

31.

The adaptive immune response to cardiac injury-the true roadblock to effective regenerative therapies?

Sattler S, Fairchild P, Watt FM, Rosenthal N, Harding SE.

NPJ Regen Med. 2017 Jun 19;2:19. doi: 10.1038/s41536-017-0022-3. eCollection 2017. Review.

32.

Fibroblast heterogeneity: implications for human disease.

Lynch MD, Watt FM.

J Clin Invest. 2018 Jan 2;128(1):26-35. doi: 10.1172/JCI93555. Epub 2018 Jan 2. Review.

33.

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.

34.

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation.

Galleu A, Riffo-Vasquez Y, Trento C, Lomas C, Dolcetti L, Cheung TS, von Bonin M, Barbieri L, Halai K, Ward S, Weng L, Chakraverty R, Lombardi G, Watt FM, Orchard K, Marks DI, Apperley J, Bornhauser M, Walczak H, Bennett C, Dazzi F.

Sci Transl Med. 2017 Nov 15;9(416). pii: eaam7828. doi: 10.1126/scitranslmed.aam7828.

35.

Osteoarthritis biomarkers: year in review.

Watt FE.

Osteoarthritis Cartilage. 2018 Mar;26(3):312-318. doi: 10.1016/j.joca.2017.10.016. Epub 2017 Oct 26. Review.

36.

Spatial constraints govern competition of mutant clones in human epidermis.

Lynch MD, Lynch CNS, Craythorne E, Liakath-Ali K, Mallipeddi R, Barker JN, Watt FM.

Nat Commun. 2017 Oct 24;8(1):1119. doi: 10.1038/s41467-017-00993-8.

37.

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis.

Mishra A, Oulès B, Pisco AO, Ly T, Liakath-Ali K, Walko G, Viswanathan P, Tihy M, Nijjher J, Dunn SJ, Lamond AI, Watt FM.

Elife. 2017 Oct 18;6. pii: e27356. doi: 10.7554/eLife.27356.

38.

Quantitative analysis of multiple elements in healthy and remodeled epithelium from human upper airway mucosa using nuclear microscopy.

Ren MQ, Zhou YT, Chen HX, Li TY, Vajandar SK, Osipowicz T, Watt F, Li CW.

Allergy. 2018 Mar;73(3):724-727. doi: 10.1111/all.13329. Epub 2017 Nov 3.

PMID:
29023780
39.

Type XVII collagen coordinates proliferation in the interfollicular epidermis.

Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuki S, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt FM, Shimizu H.

Elife. 2017 Jul 11;6. pii: e26635. doi: 10.7554/eLife.26635.

40.

Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth.

Telerman SB, Rognoni E, Sequeira I, Pisco AO, Lichtenberger BM, Culley OJ, Viswanathan P, Driskell RR, Watt FM.

J Invest Dermatol. 2017 Nov;137(11):2270-2281. doi: 10.1016/j.jid.2017.06.015. Epub 2017 Jun 28.

41.

Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ.

Nature. 2017 Jun 29;546(7660):686. doi: 10.1038/nature23012. Epub 2017 Jun 14.

PMID:
28614302
42.

Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties.

Donati G, Rognoni E, Hiratsuka T, Liakath-Ali K, Hoste E, Kar G, Kayikci M, Russell R, Kretzschmar K, Mulder KW, Teichmann SA, Watt FM.

Nat Cell Biol. 2017 Jun;19(6):603-613. doi: 10.1038/ncb3532. Epub 2017 May 15.

43.

Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ.

Nature. 2017 Jun 15;546(7658):370-375. doi: 10.1038/nature22403. Epub 2017 May 10. Erratum in: Nature. 2017 Jun 29;546(7660):686.

44.

3D map distribution of metallic nanoparticles in whole cells using MeV ion microscopy.

Vasco MS, Alves LC, Corregidor V, Correia D, Godinho CP, Sá-Correia I, Bettiol A, Watt F, Pinheiro T.

J Microsc. 2017 Aug;267(2):227-236. doi: 10.1111/jmi.12561. Epub 2017 Apr 10.

PMID:
28394445
45.

Repeal and Replace: Adipocyte Regeneration in Wound Repair.

Horsley V, Watt F.

Cell Stem Cell. 2017 Apr 6;20(4):424-426. doi: 10.1016/j.stem.2017.03.015.

46.

Minimising compassion fatigue in obstetrics/gynaecology doctors: exploring an intervention for an occupational hazard.

Allen R, Watt F, Jansen B, Coghlan E, Nathan EA.

Australas Psychiatry. 2017 Aug;25(4):403-406. doi: 10.1177/1039856217700776. Epub 2017 Mar 28.

PMID:
28347148
47.

A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.

Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM.

Nat Commun. 2017 Mar 23;8:14744. doi: 10.1038/ncomms14744.

48.

New Drug Treatments for Osteoarthritis: What is on the Horizon?

Watt FE, Gulati M.

Eur Med J Rheumatol. 2017 Mar 2;2(1):50-58.

49.

Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection.

Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM, Lechler RI, Maher J, Smyth LA, Lombardi G.

Am J Transplant. 2017 Apr;17(4):931-943. doi: 10.1111/ajt.14185. Epub 2017 Feb 1.

50.

Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.

Hayes TF, Benaich N, Goldie SJ, Sipilä K, Ames-Draycott A, Cai W, Yin G, Watt FM.

Cancer Lett. 2016 Dec 1;383(1):106-114. doi: 10.1016/j.canlet.2016.09.014. Epub 2016 Sep 28.

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