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Items: 1 to 50 of 472

1.

Mathematical modeling of intracrine androgen metabolism in prostate cancer: Methodological aspects.

Cook SF, Fiandalo MV, Watt DS, Wu Y, Mohler JL, Bies RR.

Prostate. 2018 Jun 25. doi: 10.1002/pros.23665. [Epub ahead of print]

PMID:
29938815
2.

The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores.

Dolan RD, McSorley ST, Park JH, Watt DG, Roxburgh CS, Horgan PG, McMillan DC.

Br J Cancer. 2018 Jul;119(1):40-51. doi: 10.1038/s41416-018-0095-9. Epub 2018 May 23.

PMID:
29789606
3.

Ralph Salisbury 1938-2017.

Watt DA.

Aust Vet J. 2018 May;96(5):150. doi: 10.1111/avj.12697. No abstract available.

PMID:
29691858
4.

Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade.

Fiandalo MV, Stocking JJ, Pop EA, Wilton JH, Mantione KM, Li Y, Attwood KM, Azabdaftari G, Wu Y, Watt DS, Wilson EM, Mohler JL.

Oncotarget. 2018 Jan 10;9(13):11227-11242. doi: 10.18632/oncotarget.24107. eCollection 2018 Feb 16.

5.

Phenylethynyl-substituted Heterocycles Inhibit Cyclin D1 and Induce the Expression of Cyclin-dependent Kinase Inhibitor p21Wif1/Cip1 in Colorectal Cancer Cells.

Sviripa VM, Kril LM, Zhang W, Xie Y, Wyrebek P, Ponomareva L, Liu X, Yuan Y, Zhan CG, Watt DS, Liu C.

Medchemcomm. 2018;9(1):87-99. doi: 10.1039/C7MD00393E. Epub 2017 Nov 3.

PMID:
29527286
6.

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4).

Frasinyuk MS, Zhang W, Wyrebek P, Yu T, Xu X, Sviripa VM, Bondarenko SP, Xie Y, Ngo HX, Morris AJ, Mohler JL, Fiandalo MV, Watt DS, Liu C.

Org Biomol Chem. 2017 Sep 20;15(36):7623-7629. doi: 10.1039/c7ob01584d.

PMID:
28868548
7.

Clinicopathological Determinants of an Elevated Systemic Inflammatory Response Following Elective Potentially Curative Resection for Colorectal Cancer.

Watt DG, Ramanathan ML, McSorley ST, Walley K, Park JH, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Sep;24(9):2588-2594. doi: 10.1245/s10434-017-5987-z. Epub 2017 Jul 10.

8.

Audiovisual integration in social evaluation.

Mileva M, Tompkinson J, Watt D, Burton AM.

J Exp Psychol Hum Percept Perform. 2018 Jan;44(1):128-138. doi: 10.1037/xhp0000439. Epub 2017 May 8.

PMID:
28481565
9.

Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells.

Kenlan DE, Rychahou P, Sviripa VM, Weiss HL, Liu C, Watt DS, Evers BM.

Mol Cancer Ther. 2017 May;16(5):831-837. doi: 10.1158/1535-7163.MCT-15-0634. Epub 2017 Mar 3.

10.

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.

Burikhanov R, Hebbar N, Noothi SK, Shukla N, Sledziona J, Araujo N, Kudrimoti M, Wang QJ, Watt DS, Welch DR, Maranchie J, Harada A, Rangnekar VM.

Cell Rep. 2017 Jan 10;18(2):508-519. doi: 10.1016/j.celrep.2016.12.051.

11.

A Postoperative Systemic Inflammation Score Predicts Short- and Long-Term Outcomes in Patients Undergoing Surgery for Colorectal Cancer.

Watt DG, McSorley ST, Park JH, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Apr;24(4):1100-1109. doi: 10.1245/s10434-016-5659-4. Epub 2016 Nov 7.

PMID:
27822634
12.

Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents.

Shrestha SK, Kril LM, Green KD, Kwiatkowski S, Sviripa VM, Nickell JR, Dwoskin LP, Watt DS, Garneau-Tsodikova S.

Bioorg Med Chem. 2017 Jan 1;25(1):58-66. doi: 10.1016/j.bmc.2016.10.009. Epub 2016 Oct 10.

13.

Estimating the Relative Sociolinguistic Salience of Segmental Variables in a Dialect Boundary Zone.

Llamas C, Watt D, MacFarlane AE.

Front Psychol. 2016 Aug 15;7:1163. doi: 10.3389/fpsyg.2016.01163. eCollection 2016.

14.

A quality control method enhancement concept-Continual improvement of regulatory approved QC methods.

Åsberg D, Nilsson M, Olsson S, Samuelsson J, Svensson O, Klick S, Ennis J, Butterworth P, Watt D, Iliadou S, Karlsson A, Walker JT, Arnot K, Ealer N, Hernqvist K, Svensson K, Grinell A, Quist PO, Karlsson A, Fornstedt T.

J Pharm Biomed Anal. 2016 Sep 10;129:273-281. doi: 10.1016/j.jpba.2016.06.018. Epub 2016 Jun 14.

PMID:
27442889
15.

A Fragmentary Archive: Migratory Feelings in Early Anglo-Saxon Women's Letters.

Watt D.

J Homosex. 2017;64(3):415-429. doi: 10.1080/00918369.2016.1190217. Epub 2016 May 16.

PMID:
27183969
16.

Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance.

Rentoft M, Lindell K, Tran P, Chabes AL, Buckland RJ, Watt DL, Marjavaara L, Nilsson AK, Melin B, Trygg J, Johansson E, Chabes A.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4723-8. doi: 10.1073/pnas.1519128113. Epub 2016 Apr 11.

17.

Postoperative Systemic Inflammatory Response, Complication Severity, and Survival Following Surgery for Colorectal Cancer.

McSorley ST, Watt DG, Horgan PG, McMillan DC.

Ann Surg Oncol. 2016 Sep;23(9):2832-40. doi: 10.1245/s10434-016-5204-5. Epub 2016 Mar 25.

18.

The Success and Failure of a Radiology Quality Metric: The Case of OP-10.

Blackmore CC, Watt D, Sicuro PL.

J Am Coll Radiol. 2016 Jun;13(6):630-7. doi: 10.1016/j.jacr.2016.01.006. Epub 2016 Feb 20.

PMID:
26908028
19.

Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases.

Frasinyuk MS, Mrug GP, Bondarenko SP, Khilya VP, Sviripa VM, Syrotchuk OA, Zhang W, Cai X, Fiandalo MV, Mohler JL, Liu C, Watt DS.

ChemMedChem. 2016 Mar 17;11(6):600-11. doi: 10.1002/cmdc.201600008. Epub 2016 Feb 17.

20.

Synthesis of a norcantharidin-tethered guanosine: Protein phosphatase-1 inhibitors that change alternative splicing.

Kwiatkowski S, Sviripa VM, Zhang Z, Wendlandt AE, Höbartner C, Watt DS, Stamm S.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):965-968. doi: 10.1016/j.bmcl.2015.12.054. Epub 2015 Dec 18.

21.

Advanced cardiac chemical exchange saturation transfer (cardioCEST) MRI for in vivo cell tracking and metabolic imaging.

Pumphrey A, Yang Z, Ye S, Powell DK, Thalman S, Watt DS, Abdel-Latif A, Unrine J, Thompson K, Fornwalt B, Ferrauto G, Vandsburger M.

NMR Biomed. 2016 Jan;29(1):74-83. doi: 10.1002/nbm.3451.

22.

Improvements in the management of neutropenic sepsis: lessons learned from a district general hospital.

Wells T, Thomas C, Watt D, Fountain V, Tomlinson M, Hilman S.

Clin Med (Lond). 2015 Dec;15(6):526-30. doi: 10.7861/clinmedicine.15-6-526.

PMID:
26621939
23.

Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools.

Watt DL, Buckland RJ, Lujan SA, Kunkel TA, Chabes A.

Nucleic Acids Res. 2016 Feb 29;44(4):1669-80. doi: 10.1093/nar/gkv1298. Epub 2015 Nov 24.

24.

Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin.

Sviripa VM, Burikhanov R, Obiero JM, Yuan Y, Nickell JR, Dwoskin LP, Zhan CG, Liu C, Tsodikov OV, Rangnekar VM, Watt DS.

Org Biomol Chem. 2016 Jan 7;14(1):74-84. doi: 10.1039/c5ob01980j.

25.

The Neutrophil-Platelet Score (NPS) Predicts Survival in Primary Operable Colorectal Cancer and a Variety of Common Cancers.

Watt DG, Proctor MJ, Park JH, Horgan PG, McMillan DC.

PLoS One. 2015 Nov 6;10(11):e0142159. doi: 10.1371/journal.pone.0142159. eCollection 2015.

26.

A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer.

Watt DG, Roxburgh CS, White M, Chan JZ, Horgan PG, McMillan DC.

Mediators Inflamm. 2015;2015:842070. doi: 10.1155/2015/842070. Epub 2015 Oct 4.

27.

Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents.

Frasinyuk MS, Mrug GP, Bondarenko SP, Sviripa VM, Zhang W, Cai X, Fiandalo MV, Mohler JL, Liu C, Watt DS.

Org Biomol Chem. 2015 Dec 14;13(46):11292-301. doi: 10.1039/c5ob01828e. Epub 2015 Sep 29.

28.

Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis.

Xu X, Watt DS, Liu C.

Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):82-9. doi: 10.1093/abbs/gmv083. Epub 2015 Sep 14. Review.

29.

Enhanced Recovery After Surgery: Which Components, If Any, Impact on The Systemic Inflammatory Response Following Colorectal Surgery?: A Systematic Review.

Watt DG, McSorley ST, Horgan PG, McMillan DC.

Medicine (Baltimore). 2015 Sep;94(36):e1286. doi: 10.1097/MD.0000000000001286.

30.

N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells.

Kril LM, Vilchez V, Jiang J, Turcios L, Chen C, Sviripa VM, Zhang W, Liu C, Spear B, Watt DS, Gedaly R.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3897-9. doi: 10.1016/j.bmcl.2015.07.040. Epub 2015 Jul 26.

31.

Development of 6H-Chromeno[3,4-c]pyrido[3',2':4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 Secretagogues.

Frasinyuk MS, Bondarenko SP, Sviripa VM, Burikhanov R, Rangnekar VM, Liu C, Watt DS.

Tetrahedron Lett. 2015 Jun 3;56(23):3382-3384.

32.

Analysis of trans-2,6-difluoro-4'-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics.

Yeo SC, Sviripa VM, Huang M, Kril L, Watt DS, Liu C, Lin HS.

Anal Bioanal Chem. 2015 Sep;407(24):7319-32. doi: 10.1007/s00216-015-8893-x. Epub 2015 Jul 31.

PMID:
26229026
33.

30-Day and 1-year mortality in emergency general surgery laparotomies: an area of concern and need for improvement?

Watt DG, Wilson MS, Shapter OC, Patil P.

Eur J Trauma Emerg Surg. 2015 Aug;41(4):369-74. doi: 10.1007/s00068-014-0450-3. Epub 2014 Sep 23.

PMID:
26037986
34.

JIP3 Activates Kinesin-1 Motility to Promote Axon Elongation.

Watt D, Dixit R, Cavalli V.

J Biol Chem. 2015 Jun 19;290(25):15512-25. doi: 10.1074/jbc.M115.651885. Epub 2015 May 5.

35.

Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration.

Song W, Cho Y, Watt D, Cavalli V.

J Biol Chem. 2015 Jun 5;290(23):14765-75. doi: 10.1074/jbc.M114.622753. Epub 2015 Apr 24.

36.

Comment on "prognostic performance of inflammation-based prognostic indices in patients with resectable colorectal liver metastases".

Watt DG, Horgan PG, McMillan DC.

Med Oncol. 2015 May;32(5):167. doi: 10.1007/s12032-015-0617-8. Epub 2015 Apr 23. No abstract available.

PMID:
25904501
37.

Neutrophil count is the most important prognostic component of the differential white cell count in patients undergoing elective surgery for colorectal cancer.

Watt DG, Martin JC, Park JH, Horgan PG, McMillan DC.

Am J Surg. 2015 Jul;210(1):24-30. doi: 10.1016/j.amjsurg.2014.12.031. Epub 2015 Mar 12.

PMID:
25842358
38.

The King-Devick test for sideline concussion screening in collegiate football.

Leong DF, Balcer LJ, Galetta SL, Evans G, Gimre M, Watt D.

J Optom. 2015 Apr-Jun;8(2):131-9. doi: 10.1016/j.optom.2014.12.005. Epub 2015 Jan 31.

39.

Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation: a systematic review.

Watt DG, Horgan PG, McMillan DC.

Surgery. 2015 Feb;157(2):362-80. doi: 10.1016/j.surg.2014.09.009. Review.

PMID:
25616950
40.

Colorectal Cancer, Systemic Inflammation, and Outcome: Staging the Tumor and Staging the Host.

Park JH, Watt DG, Roxburgh CS, Horgan PG, McMillan DC.

Ann Surg. 2016 Feb;263(2):326-36. doi: 10.1097/SLA.0000000000001122.

PMID:
25575264
41.

Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity.

Buckland RJ, Watt DL, Chittoor B, Nilsson AK, Kunkel TA, Chabes A.

PLoS Genet. 2014 Dec 4;10(12):e1004846. doi: 10.1371/journal.pgen.1004846. eCollection 2014 Dec.

42.

Tritium-labeled (E,E)-2,5-bis(4'-hydroxy-3'-carboxystyryl)benzene as a probe for β-amyloid fibrils.

Matveev SV, Kwiatkowski S, Sviripa VM, Fazio RC, Watt DS, LeVine H 3rd.

Bioorg Med Chem Lett. 2014 Dec 1;24(23):5534-6. doi: 10.1016/j.bmcl.2014.09.075. Epub 2014 Oct 6.

43.

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals.

Frasinyuk MS, Bondarenko SP, Khilya VP, Liu C, Watt DS, Sviripa VM.

Org Biomol Chem. 2015 Jan 28;13(4):1053-67. doi: 10.1039/c4ob02137a. Epub 2014 Nov 21.

44.

Application of the 4D fingerprint method with a robust scoring function for scaffold-hopping and drug repurposing strategies.

Hamza A, Wagner JM, Wei NN, Kwiatkowski S, Zhan CG, Watt DS, Korotkov KV.

J Chem Inf Model. 2014 Oct 27;54(10):2834-45. doi: 10.1021/ci5003872. Epub 2014 Oct 7.

45.

Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis.

Burikhanov R, Sviripa VM, Hebbar N, Zhang W, Layton WJ, Hamza A, Zhan CG, Watt DS, Liu C, Rangnekar VM.

Nat Chem Biol. 2014 Nov;10(11):924-926. doi: 10.1038/nchembio.1631. Epub 2014 Sep 14.

46.

Relighting the fire: visualizing the lesbian in contemporary India.

Mahn C, Watt D.

J Lesbian Stud. 2014;18(3):223-36. doi: 10.1080/10894160.2014.896611.

PMID:
24972282
47.

2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2.

Sviripa VM, Zhang W, Balia AG, Tsodikov OV, Nickell JR, Gizard F, Yu T, Lee EY, Dwoskin LP, Liu C, Watt DS.

J Med Chem. 2014 Jul 24;57(14):6083-91. doi: 10.1021/jm5004864. Epub 2014 Jul 9.

48.

Halogenated diarylacetylenes repress c-myc expression in cancer cells.

Sviripa VM, Zhang W, Kril LM, Liu AX, Yuan Y, Zhan CG, Liu C, Watt DS.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3638-40. doi: 10.1016/j.bmcl.2014.04.113. Epub 2014 May 9.

49.

Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease.

Frasinyuk MS, Kwiatkowski S, Wagner JM, Evans TJ, Reed RW, Korotkov KV, Watt DS.

Bioorg Med Chem Lett. 2014 Aug 1;24(15):3546-8. doi: 10.1016/j.bmcl.2014.05.056. Epub 2014 May 27.

50.

Novel mycosin protease MycP₁ inhibitors identified by virtual screening and 4D fingerprints.

Hamza A, Wagner JM, Evans TJ, Frasinyuk MS, Kwiatkowski S, Zhan CG, Watt DS, Korotkov KV.

J Chem Inf Model. 2014 Apr 28;54(4):1166-73. doi: 10.1021/ci500025r. Epub 2014 Mar 27.

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