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Low-dose lithium feeding increases the SERCA2a to phospholamban ratio improving SERCA function in murine left ventricles.

Hamstra SI, Kurgan N, Baranowski RW, Qiu L, Watson CJF, Messner HN, MacPherson REK, MacNeil AJ, Roy BD, Fajardo VA.

Exp Physiol. 2020 Feb 22. doi: 10.1113/EP088061. [Epub ahead of print]


Novel Organ Perfusion and Preservation Strategies in Transplantation - where are we going in the UK?

O'Neill S, Srinivasa S, Callaghan CJ, Watson CJ, Dark JH, Fisher AJ, Wilson CH, Friend PJ, Johnson R, Forsythe JL, Ploeg RJ, Mirza DF, Wigmore SJ, Oniscu GC.

Transplantation. 2020 Jan 13. doi: 10.1097/TP.0000000000003106. [Epub ahead of print]


Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: A United Kingdom and Canadian proposal.

Manara A, Shemie SD, Large S, Healey A, Baker A, Badiwala M, Berman M, Butler AJ, Chaudhury P, Dark J, Forsythe J, Freed DH, Gardiner D, Harvey D, Hornby L, MacLean J, Messer S, Oniscu GC, Simpson C, Teitelbaum J, Torrance S, Wilson LC, Watson CJE.

Am J Transplant. 2020 Jan 10. doi: 10.1111/ajt.15775. [Epub ahead of print]


New-onset heart failure in the STOP-HF programme. Natriuretic peptide defines and tracks risk and enables earlier diagnosis of heart failure.

McClelland S, Zhou S, O'Connell E, Gallagher J, Ryan F, Watson CJ, Ledwidge M, McDonald K.

Eur J Heart Fail. 2020 Jan 7. doi: 10.1002/ejhf.1661. [Epub ahead of print] No abstract available.


Toxicity of agents used for opioid withdrawal: a case-based approach.

Watson CJ, Whitledge JD, Barbuto AF, Boyle KL, Ganetsky M.

Int Anesthesiol Clin. 2020 Jan 3. doi: 10.1097/AIA.0000000000000265. [Epub ahead of print] No abstract available.


Increasing long-acting reversible contraceptives: the Australian Contraceptive ChOice pRoject (ACCORd) cluster randomized trial.

Mazza D, Watson CJ, Taft A, Lucke J, McGeechan K, Haas M, McNamee K, Peipert JF, Black KI.

Am J Obstet Gynecol. 2019 Dec 16. pii: S0002-9378(19)32688-2. doi: 10.1016/j.ajog.2019.11.1267. [Epub ahead of print]


UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues.

Vergara AG, Watson CJW, Chen G, Lazarus P.

Drug Metab Dispos. 2020 Mar;48(3):160-168. doi: 10.1124/dmd.119.089284. Epub 2019 Dec 13.


Difficult Intraoperative Heparinization Following Andexanet Alfa Administration.

Watson CJ, Zettervall SL, Hall MM, Ganetsky M.

Clin Pract Cases Emerg Med. 2019 Oct 14;3(4):390-394. doi: 10.5811/cpcem.2019.9.43650. eCollection 2019 Nov.


Dynamic architectural interplay between leucocytes and mammary epithelial cells.

Hitchcock JR, Hughes K, Harris OB, Watson CJ.

FEBS J. 2020 Jan;287(2):250-266. doi: 10.1111/febs.15126. Epub 2019 Nov 29.


Spinal cord ischemia in pancreas transplantation: the UK experience.

Phillips BL, Papadakis G, Bell R, Sinha S, Callaghan CJ, Akyol M, Watson CJE, Drage M.

Transplantation. 2019 Oct 23. doi: 10.1097/TP.0000000000003028. [Epub ahead of print]


The Novel CYP2A6 Inhibitor, DLCI-1, Decreases Nicotine Self-Administration in Mice.

Chen YC, Fowler JP, Wang J, Watson CJW, Sherafat Y, Staben A, Lazarus P, Denton TT, Fowler CD.

J Pharmacol Exp Ther. 2020 Jan;372(1):21-29. doi: 10.1124/jpet.119.260653. Epub 2019 Oct 18.


Response to Caro and Winter.

Harte SE, Clauw DJ, Feldman EL, Watson CJ.

Pain Rep. 2019 Apr 15;4(3):e734. doi: 10.1097/PR9.0000000000000734. eCollection 2019 May-Jun. No abstract available.


Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNAL.

Kozlovich S, Chen G, Watson CJW, Blot WJ, Lazarus P.

Drug Metab Dispos. 2019 Dec;47(12):1388-1396. doi: 10.1124/dmd.119.088351. Epub 2019 Oct 2.


Potential Regulation of UGT2B10 and UGT2B7 by miR-485-5p in Human Liver.

Sutliff AK, Shi J, Watson CJW, Hunt MS, Chen G, Zhu HJ, Lazarus P.

Mol Pharmacol. 2019 Dec;96(6):674-682. doi: 10.1124/mol.119.115881. Epub 2019 Sep 25.


Early remote ischaemic preconditioning leads to sustained improvement in allograft function after live donor kidney transplantation: long-term outcomes in the REnal Protection Against Ischaemia-Reperfusion in transplantation (REPAIR) randomised trial.

Veighey KV, Nicholas JM, Clayton T, Knight R, Robertson S, Dalton N, Harber M, Watson CJE, De Fijter JW, Loukogeorgakis S, MacAllister R.

Br J Anaesth. 2019 Nov;123(5):584-591. doi: 10.1016/j.bja.2019.07.019. Epub 2019 Sep 11.


Service evaluation of diabetes management during pregnancy in a regional maternity hospital: potential scope for increased self-management and remote patient monitoring through mHealth solutions.

Alqudah A, McMullan P, Todd A, O'Doherty C, McVey A, McConnell M, O'Donoghue J, Gallagher J, Watson CJ, McClements L.

BMC Health Serv Res. 2019 Sep 13;19(1):662. doi: 10.1186/s12913-019-4471-9.


Recipient Comorbidity and Survival Outcomes after Kidney Transplantation: a UK-wide Prospective Cohort Study.

Wu DA, Robb ML, Forsythe JLR, Bradley C, Cairns J, Draper H, Dudley C, Johnson RJ, Metcalfe W, Ravanan R, Roderick P, Tomson CRV, Watson CJE, Bradley JA, Oniscu GC.

Transplantation. 2019 Aug 19. doi: 10.1097/TP.0000000000002931. [Epub ahead of print]


Neurogranin is expressed in mammalian skeletal muscle and inhibits calcineurin signaling and myoblast fusion.

Fajardo VA, Watson CJF, Bott KN, Moradi F, Maddalena LA, Bellissimo CA, Turner KD, Peters SJ, LeBlanc PJ, MacNeil AJ, Stuart JA, Tupling AR.

Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C1025-C1033. doi: 10.1152/ajpcell.00345.2018. Epub 2019 Aug 21.


Equity-efficiency trade-offs associated with alternative approaches to deceased donor kidney allocation: a patient-level simulation.

Li B, Cairns JA, Johnson RJ, Watson CJE, Roderick P, Oniscu GC, Metcalfe W, Bradley JA, Tomson CR, Draper H, Forsythe JL, Dudley C, Ravanan R.

Transplantation. 2019 Aug 8. doi: 10.1097/TP.0000000000002910. [Epub ahead of print]


Cold pulsatile machine perfusion versus static cold storage for kidneys donated after circulatory death: a multicenter randomized controlled trial.

Summers DM, Ahmad N, Randle LV, O'Sullivan AM, Johnson RJ, Collett D, Attia M, Clancy M, Tavakoli A, Akyol M, Jamieson NV, Bradley JA, Watson CJ.

Transplantation. 2019 Aug 8. doi: 10.1097/TP.0000000000002907. [Epub ahead of print]


Prominent Stereoselectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues.

Kozlovich S, Chen G, Watson CJW, Lazarus P.

Chem Res Toxicol. 2019 Aug 19;32(8):1689-1698. doi: 10.1021/acs.chemrestox.9b00217. Epub 2019 Jul 30.


Modeling biodiversity benchmarks in variable environments.

Yen JDL, Dorrough J, Oliver I, Somerville M, McNellie MJ, Watson CJ, Vesk PA.

Ecol Appl. 2019 Oct;29(7):e01970. doi: 10.1002/eap.1970. Epub 2019 Jul 30.


Transient Cold Storage Prior to Normothermic Liver Perfusion May Facilitate Adoption of a Novel Technology.

Ceresa CDL, Nasralla D, Watson CJE, Butler AJ, Coussios CC, Crick K, Hodson L, Imber C, Jassem W, Knight SR, Mergental H, Ploeg RJ, Pollok JM, Quaglia A, Shapiro AMJ, Weissenbacher A, Friend PJ.

Liver Transpl. 2019 Oct;25(10):1503-1513. doi: 10.1002/lt.25584. Epub 2019 Jul 18.


Maternal Noninfectious Fever Enhances Cell Proliferation and Microglial Activation in the Neonatal Rat Dentate Gyrus.

Pancaro C, Boulanger-Bertolus J, Segal S, Watson CJ, St Charles I, Mashour GA, Marchand JE.

Anesth Analg. 2019 Jun;128(6):1190-1198. doi: 10.1213/ANE.0000000000004051.


Limited health literacy is associated with reduced access to kidney transplantation.

Taylor DM, Bradley JA, Bradley C, Draper H, Dudley C, Fogarty D, Fraser S, Johnson R, Leydon GM, Metcalfe W, Oniscu GC, Robb M, Tomson C, Watson CJE, Ravanan R, Roderick P; ATTOM investigators.

Kidney Int. 2019 May;95(5):1244-1252. doi: 10.1016/j.kint.2018.12.021. Epub 2019 Apr 2.


NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes post-ischaemic revascularization.

O'Neill KM, Campbell DC, Edgar KS, Gill EK, Moez A, McLoughlin KJ, O'Neill CL, Dellett M, Hargey CJ, Abudalo RA, O'Hare M, Doyle P, Toh T, Khoo J, Wong J, McCrudden CM, Meloni M, Brunssen C, Morawietz H, Yoder MC, McDonald DM, Watson CJ, Stitt AW, Margariti A, Medina RJ, Grieve DJ.

Cardiovasc Res. 2020 Feb 1;116(2):393-405. doi: 10.1093/cvr/cvz090.


Direct Procurement of Donor Heart With Normothermic Regional Perfusion of Abdominal Organs.

Mohite PN, García Sáez D, Butler AJ, Watson CJE, Simon A.

Ann Thorac Surg. 2019 Aug;108(2):597-600. doi: 10.1016/j.athoracsur.2019.01.087. Epub 2019 Mar 23.


Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p.

Sutliff AK, Watson CJW, Chen G, Lazarus P.

J Pharmacol Exp Ther. 2019 May;369(2):234-243. doi: 10.1124/jpet.118.255935. Epub 2019 Mar 8.


Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.

Liu SN, Lu JBL, Watson CJW, Lazarus P, Desta Z, Gufford BT.

Drug Metab Dispos. 2019 May;47(5):535-544. doi: 10.1124/dmd.118.085035. Epub 2019 Feb 25.


Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes.

Glezeva N, Moran B, Collier P, Moravec CS, Phelan D, Donnellan E, Russell-Hallinan A, O'Connor DP, Gallagher WM, Gallagher J, McDonald K, Ledwidge M, Baugh J, Das S, Watson CJ.

Circ Heart Fail. 2019 Mar;12(3):e005765. doi: 10.1161/CIRCHEARTFAILURE.118.005765.


Using zebrafish to study skeletal genomics.

Kwon RY, Watson CJ, Karasik D.

Bone. 2019 Sep;126:37-50. doi: 10.1016/j.bone.2019.02.009. Epub 2019 Feb 11.


Nitrogen use efficiency and nitrous oxide emissions from five UK fertilised grasslands.

Cardenas LM, Bhogal A, Chadwick DR, McGeough K, Misselbrook T, Rees RM, Thorman RE, Watson CJ, Williams JR, Smith KA, Calvet S.

Sci Total Environ. 2019 Apr 15;661:696-710. doi: 10.1016/j.scitotenv.2019.01.082. Epub 2019 Jan 9.


In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival.

Watson CJE, Hunt F, Messer S, Currie I, Large S, Sutherland A, Crick K, Wigmore SJ, Fear C, Cornateanu S, Randle LV, Terrace JD, Upponi S, Taylor R, Allen E, Butler AJ, Oniscu GC.

Am J Transplant. 2019 Jun;19(6):1745-1758. doi: 10.1111/ajt.15241. Epub 2019 Feb 1.


Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.

Perez-Paramo YX, Chen G, Ashmore JH, Watson CJW, Nasrin S, Adams-Haduch J, Wang R, Gao YT, Koh WP, Yuan JM, Lazarus P.

Cancer Epidemiol Biomarkers Prev. 2019 Feb;28(2):311-320. doi: 10.1158/1055-9965.EPI-18-0669. Epub 2018 Oct 31.


Tumour cell invasiveness and response to chemotherapeutics in adipocyte invested 3D engineered anisotropic collagen scaffolds.

Hume RD, Pensa S, Brown EJ, Kreuzaler PA, Hitchcock J, Husmann A, Campbell JJ, Lloyd-Thomas AO, Cameron RE, Watson CJ.

Sci Rep. 2018 Aug 23;8(1):12658. doi: 10.1038/s41598-018-30107-3.


Discovery of Novel Caeridins from the Skin Secretion of the Australian White's Tree Frog, Litoria caerulea.

Li L, Wu Q, Wang X, Lu H, Xi X, Zhou M, Watson CJ, Chen T, Wang L.

Int J Genomics. 2018 Jul 11;2018:8158453. doi: 10.1155/2018/8158453. eCollection 2018.


Neutral lineage tracing of proliferative embryonic and adult mammary stem/progenitor cells.

Lloyd-Lewis B, Davis FM, Harris OB, Hitchcock JR, Watson CJ.

Development. 2018 Jul 25;145(14). pii: dev164079. doi: 10.1242/dev.164079.


Identification of the 4-Position of 3-Alkynyl and 3-Heteroaromatic Substituted Pyridine Methanamines as a Key Modification Site Eliciting Increased Potency and Enhanced Selectivity for Cytochrome P-450 2A6 Inhibition.

Denton TT, Srivastava P, Xia Z, Chen G, Watson CJW, Wynd A, Lazarus P.

J Med Chem. 2018 Aug 23;61(16):7065-7086. doi: 10.1021/acs.jmedchem.8b00084. Epub 2018 Aug 1.


Differential Role of Prefrontal and Parietal Cortices in Controlling Level of Consciousness.

Pal D, Dean JG, Liu T, Li D, Watson CJ, Hudetz AG, Mashour GA.

Curr Biol. 2018 Jul 9;28(13):2145-2152.e5. doi: 10.1016/j.cub.2018.05.025. Epub 2018 Jun 21.


Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.

Banham GD, Flint SM, Torpey N, Lyons PA, Shanahan DN, Gibson A, Watson CJE, O'Sullivan AM, Chadwick JA, Foster KE, Jones RB, Devey LR, Richards A, Erwig LP, Savage CO, Smith KGC, Henderson RB, Clatworthy MR.

Lancet. 2018 Jun 30;391(10140):2619-2630. doi: 10.1016/S0140-6736(18)30984-X. Epub 2018 Jun 14.


Heart Failure in Sub-Saharan Africa.

Gallagher J, McDonald K, Ledwidge M, Watson CJ.

Card Fail Rev. 2018 May;4(1):21-24. doi: 10.15420/cfr.2018:4:1. Review.


The Multifaceted Role of STAT3 in Mammary Gland Involution and Breast Cancer.

Hughes K, Watson CJ.

Int J Mol Sci. 2018 Jun 7;19(6). pii: E1695. doi: 10.3390/ijms19061695. Review.


Assessing Consensus Between UK Renal Clinicians on Listing for Kidney Transplantation: A Modified Delphi Study.

Tonkin-Crine S, Pruthi R, Taylor DM, Leydon GM, Calestani M, Oniscu GC, Bradley JA, Tomson CR, Bradley C, Dudley C, Watson CJE, Draper H, Johnson RJ, Metcalfe W, Fogarty DG, Ravanan R, Roderick P.

Transplant Direct. 2018 Apr 18;4(5):e343. doi: 10.1097/TXD.0000000000000782. eCollection 2018 May.


Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung.

Ashmore JH, Luo S, Watson CJW, Lazarus P.

Carcinogenesis. 2018 Jul 30;39(8):1079-1088. doi: 10.1093/carcin/bgy065.


The Mammary Microenvironment in Mastitis in Humans, Dairy Ruminants, Rabbits and Rodents: A One Health Focus.

Hughes K, Watson CJ.

J Mammary Gland Biol Neoplasia. 2018 Jun;23(1-2):27-41. doi: 10.1007/s10911-018-9395-1. Epub 2018 Apr 28. Review.


Epigenetics of Aberrant Cardiac Wound Healing.

Russell-Hallinan A, Watson CJ, Baugh JA.

Compr Physiol. 2018 Mar 26;8(2):451-491. doi: 10.1002/cphy.c170029. Review.


The contribution of cattle urine and dung to nitrous oxide emissions: Quantification of country specific emission factors and implications for national inventories.

Chadwick DR, Cardenas LM, Dhanoa MS, Donovan N, Misselbrook T, Williams JR, Thorman RE, McGeough KL, Watson CJ, Bell M, Anthony SG, Rees RM.

Sci Total Environ. 2018 Sep 1;635:607-617. doi: 10.1016/j.scitotenv.2018.04.152. Epub 2018 Apr 24.


A randomized trial of normothermic preservation in liver transplantation.

Nasralla D, Coussios CC, Mergental H, Akhtar MZ, Butler AJ, Ceresa CDL, Chiocchia V, Dutton SJ, García-Valdecasas JC, Heaton N, Imber C, Jassem W, Jochmans I, Karani J, Knight SR, Kocabayoglu P, Malagò M, Mirza D, Morris PJ, Pallan A, Paul A, Pavel M, Perera MTPR, Pirenne J, Ravikumar R, Russell L, Upponi S, Watson CJE, Weissenbacher A, Ploeg RJ, Friend PJ; Consortium for Organ Preservation in Europe.

Nature. 2018 May;557(7703):50-56. doi: 10.1038/s41586-018-0047-9. Epub 2018 Apr 18.


An Engineered Human Adipose/Collagen Model for In Vitro Breast Cancer Cell Migration Studies.

Hume RD, Berry L, Reichelt S, D'Angelo M, Gomm J, Cameron RE, Watson CJ.

Tissue Eng Part A. 2018 Sep;24(17-18):1309-1319. doi: 10.1089/ten.TEA.2017.0509. Epub 2018 Jul 3.


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