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Items: 1 to 50 of 588

1.

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ.

Mol Cell. 2019 Oct 3;76(1):217. doi: 10.1016/j.molcel.2019.08.009. No abstract available.

2.

Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.

Ghosh S, Padmanabhan A, Vaidya T, Watson AM, Bhutto IA, Hose S, Shang P, Stepicheva N, Yazdankhah M, Weiss J, Das M, Gopikrishna S, Aishwarya, Yadav N, Berger T, Mak TW, Xia S, Qian J, Lutty GA, Jayagopal A, Zigler JS Jr, Sethu S, Handa JT, Watkins SC, Ghosh A, Sinha D.

Commun Biol. 2019 Sep 20;2:348. doi: 10.1038/s42003-019-0588-y. eCollection 2019.

3.

Platelet Extracellular Vesicles Drive Inflammasome-IL1β-dependent Lung Injury in Sickle Cell Disease.

Vats R, Brzoska T, Bennewitz MF, Jimenez MA, Pradhan-Sundd T, Tutuncuoglu E, Jonassaint J, Gutierrez E, Watkins SC, Shiva S, Scott M, Morelli AE, Neal MD, Kato GJ, Gladwin MT, Sundd P.

Am J Respir Crit Care Med. 2019 Sep 9. doi: 10.1164/rccm.201807-1370OC. [Epub ahead of print]

PMID:
31498653
4.

Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction.

Qian W, Kumar N, Roginskaya V, Fouquerel E, Opresko PL, Shiva S, Watkins SC, Kolodieznyi D, Bruchez MP, Van Houten B.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18435-18444. doi: 10.1073/pnas.1910574116. Epub 2019 Aug 26.

5.

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ.

Mol Cell. 2019 Oct 3;76(1):11-26.e7. doi: 10.1016/j.molcel.2019.06.043. Epub 2019 Aug 7. Erratum in: Mol Cell. 2019 Oct 3;76(1):217.

PMID:
31400850
6.

Antigen-dependent interactions between regulatory B cells and T cells at the T:B border inhibit subsequent T cell interactions with DCs.

Mohib K, Cherukuri A, Zhou Y, Ding Q, Watkins SC, Rothstein DM.

Am J Transplant. 2019 Jul 29. doi: 10.1111/ajt.15546. [Epub ahead of print]

PMID:
31355483
7.

Damage sensor role of UV-DDB during base excision repair.

Jang S, Kumar N, Beckwitt EC, Kong M, Fouquerel E, Rapić-Otrin V, Prasad R, Watkins SC, Khuu C, Majumdar C, David SS, Wilson SH, Bruchez MP, Opresko PL, Van Houten B.

Nat Struct Mol Biol. 2019 Aug;26(8):695-703. doi: 10.1038/s41594-019-0261-7. Epub 2019 Jul 22.

PMID:
31332353
8.

An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication.

Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E, Watkins SC, Bakkenist CJ.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13374-13383. doi: 10.1073/pnas.1903418116. Epub 2019 Jun 17.

9.

The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection.

Piccirillo AR, Hyzny EJ, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM.

J Immunol. 2019 Jul 1;203(1):117-126. doi: 10.4049/jimmunol.1801585. Epub 2019 May 24.

PMID:
31127034
10.

Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis.

Fouquerel E, Barnes RP, Uttam S, Watkins SC, Bruchez MP, Opresko PL.

Mol Cell. 2019 Jul 11;75(1):117-130.e6. doi: 10.1016/j.molcel.2019.04.024. Epub 2019 May 14.

PMID:
31101499
11.

Massive volumetric imaging of cleared tissue: The necessary tools to be successful.

Watson AM, Watkins SC.

Int J Biochem Cell Biol. 2019 Jul;112:76-78. doi: 10.1016/j.biocel.2019.05.007. Epub 2019 May 11.

PMID:
31085331
12.

Redox (phospho)lipidomics of signaling in inflammation and programmed cell death.

Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, Bolevich SB, Timashev PS, Kellum JA, Wenzel SE, Mallampalli RK, Greenberger JS, Bayir H, Shvedova AA, Kagan VE.

J Leukoc Biol. 2019 Jul;106(1):57-81. doi: 10.1002/JLB.3MIR0119-004RR. Epub 2019 May 9. Review.

13.

Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis.

Larsen MB, Perez Verdaguer M, Schmidt BF, Bruchez MP, Watkins SC, Sorkin A.

Elife. 2019 May 8;8. pii: e46135. doi: 10.7554/eLife.46135.

14.

Learn to segment single cells with deep distance estimator and deep cell detector.

Wang W, Taft DA, Chen YJ, Zhang J, Wallace CT, Xu M, Watkins SC, Xing J.

Comput Biol Med. 2019 May;108:133-141. doi: 10.1016/j.compbiomed.2019.04.006. Epub 2019 Apr 8.

PMID:
31005005
15.

Targeting the Temporal Dynamics of Hypoxia-Induced Tumor-Secreted Factors Halts Tumor Migration.

Singh M, Tian XJ, Donnenberg VS, Watson AM, Zhang J, Stabile LP, Watkins SC, Xing J, Sant S.

Cancer Res. 2019 Jun 1;79(11):2962-2977. doi: 10.1158/0008-5472.CAN-18-3151. Epub 2019 Apr 5.

PMID:
30952634
16.

Enhancing regeneration after acute kidney injury by promoting cellular dedifferentiation in zebrafish.

Brilli Skvarca L, Han HI, Espiritu EB, Missinato MA, Rochon ER, McDaniels MD, Bais AS, Roman BL, Waxman JS, Watkins SC, Davidson AJ, Tsang M, Hukriede NA.

Dis Model Mech. 2019 Apr 5;12(4). pii: dmm037390. doi: 10.1242/dmm.037390.

17.

Drosophila Ptp4E regulates vesicular packaging for monoamine-neuropeptide co-transmission.

Tao J, Bulgari D, Berkhoudt DA, Calderon MJ, Watkins SC, Fonseca Velez HJ, Sabeva N, Deitcher DL, Levitan ES.

J Cell Sci. 2019 Apr 3;132(7). pii: jcs224568. doi: 10.1242/jcs.224568.

18.

CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes.

Fischer DK, Saito A, Kline C, Cohen R, Watkins SC, Yamashita M, Ambrose Z.

J Virol. 2019 Apr 17;93(9). pii: e00214-19. doi: 10.1128/JVI.00214-19. Print 2019 May 1.

19.

Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila.

Raza Q, Choi JY, Li Y, O'Dowd RM, Watkins SC, Chikina M, Hong Y, Clark NL, Kwiatkowski AV.

PLoS Genet. 2019 Feb 14;15(2):e1007720. doi: 10.1371/journal.pgen.1007720. eCollection 2019 Feb.

20.

Secondary-Ion Mass Spectrometry Images Cardiolipins and Phosphatidylethanolamines at the Subcellular Level.

Tian H, Sparvero LJ, Blenkinsopp P, Amoscato AA, Watkins SC, Bayır H, Kagan VE, Winograd N.

Angew Chem Int Ed Engl. 2019 Mar 4;58(10):3156-3161. doi: 10.1002/anie.201814256. Epub 2019 Feb 14.

PMID:
30680861
21.

The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics.

Li Y, Merkel CD, Zeng X, Heier JA, Cantrell PS, Sun M, Stolz DB, Watkins SC, Yates NA, Kwiatkowski AV.

J Cell Sci. 2019 Feb 11;132(3). pii: jcs221606. doi: 10.1242/jcs.221606.

22.

Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells.

Surve SV, Myers PJ, Clayton SA, Watkins SC, Lazzara MJ, Sorkin A.

Mol Biol Cell. 2019 Feb 15;30(4):506-523. doi: 10.1091/mbc.E18-08-0512. Epub 2018 Dec 26.

23.

Anesthetic Considerations for Pediatric Patients With Congenital Long QT Syndrome.

Staudt GE, Watkins SC.

J Cardiothorac Vasc Anesth. 2019 Jul;33(7):2030-2038. doi: 10.1053/j.jvca.2018.11.005. Epub 2018 Nov 12. Review. No abstract available.

PMID:
30553610
24.

The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression.

Oh H, Piantadosi SC, Rocco BR, Lewis DA, Watkins SC, Sibille E.

Biol Psychiatry. 2019 Mar 15;85(6):517-526. doi: 10.1016/j.biopsych.2018.09.026. Epub 2018 Oct 9.

PMID:
30449530
25.

Development and Pilot Testing of a Context-Relevant Safe Anesthesia Checklist for Cesarean Delivery in East Africa.

Alexander LA, Newton MW, McEvoy KG, Newton MJ, Mungai M, DiMiceli-Zsigmond M, Sileshi B, Watkins SC, McEvoy MD.

Anesth Analg. 2019 May;128(5):993-998. doi: 10.1213/ANE.0000000000003874.

PMID:
30379674
26.

Freshwater Viromes: From Sampling to Evaluation.

Putonti C, Diener Z, Watkins SC.

Methods Mol Biol. 2018;1849:17-27. doi: 10.1007/978-1-4939-8728-3_2.

PMID:
30298245
27.

Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor.

Krainz T, Lamade AM, Du L, Maskrey TS, Calderon MJ, Watkins SC, Epperly MW, Greenberger JS, Bayır H, Wipf P, Clark RSB.

ACS Chem Biol. 2018 Oct 19;13(10):2868-2879. doi: 10.1021/acschembio.8b00423. Epub 2018 Sep 14.

28.

Vertebrate myosin 1d regulates left-right organizer morphogenesis and laterality.

Saydmohammed M, Yagi H, Calderon M, Clark MJ, Feinstein T, Sun M, Stolz DB, Watkins SC, Amack JD, Lo CW, Tsang M.

Nat Commun. 2018 Aug 23;9(1):3381. doi: 10.1038/s41467-018-05866-2.

29.

Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells.

Sannino S, Guerriero CJ, Sabnis AJ, Stolz DB, Wallace CT, Wipf P, Watkins SC, Bivona TG, Brodsky JL.

J Cell Sci. 2018 Sep 5;131(17). pii: jcs217760. doi: 10.1242/jcs.217760.

30.

A High-Content Screen Reveals New Small-Molecule Enhancers of Ras/Mapk Signaling as Probes for Zebrafish Heart Development.

Saydmohammed M, Vollmer LL, Onuoha EO, Maskrey TS, Gibson G, Watkins SC, Wipf P, Vogt A, Tsang M.

Molecules. 2018 Jul 11;23(7). pii: E1691. doi: 10.3390/molecules23071691.

31.

Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice.

Pradhan-Sundd T, Vats R, Russell JO, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P.

Gastroenterology. 2018 Oct;155(4):1218-1232.e24. doi: 10.1053/j.gastro.2018.06.048. Epub 2018 Jun 30.

32.

Pseudomonas PB1-Like Phages: Whole Genomes from Metagenomes Offer Insight into an Abundant Group of Bacteriophages.

Watkins SC, Sible E, Putonti C.

Viruses. 2018 Jun 16;10(6). pii: E331. doi: 10.3390/v10060331.

33.

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

Zhao J, Zhang L, Mu X, Doebelin C, Nguyen W, Wallace C, Reay DP, McGowan SJ, Corbo L, Clemens PR, Wilson GM, Watkins SC, Solt LA, Cameron MD, Huard J, Niedernhofer LJ, Kamenecka TM, Robbins PD.

PLoS Biol. 2018 Jun 11;16(6):e2004663. doi: 10.1371/journal.pbio.2004663. eCollection 2018 Jun.

34.

High-Resolution, Three-Dimensional Reconstruction of the Outflow Tract Demonstrates Segmental Differences in Cleared Eyes.

Waxman S, Loewen RT, Dang Y, Watkins SC, Watson AM, Loewen NA.

Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2371-2380. doi: 10.1167/iovs.17-23075.

35.

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.

Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ.

Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13.

36.

Creating a Quality Improvement Course for Undergraduate Medical Education: Practice What You Teach.

Bradham TS, Sponsler KC, Watkins SC, Ehrenfeld JM.

Acad Med. 2018 Oct;93(10):1491-1496. doi: 10.1097/ACM.0000000000002253.

PMID:
29727320
37.

Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence.

Choy CH, Saffi G, Gray MA, Wallace C, Dayam RM, Ou ZA, Lenk G, Puertollano R, Watkins SC, Botelho RJ.

J Cell Sci. 2018 May 21;131(10). pii: jcs213587. doi: 10.1242/jcs.213587.

38.

Light sheet imaging comes of age.

Watkins SC, St Croix CM.

J Cell Biol. 2018 May 7;217(5):1567-1569. doi: 10.1083/jcb.201804016. Epub 2018 Apr 13.

39.

Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid.

Ning J, Zhong Z, Fischer DK, Harris G, Watkins SC, Ambrose Z, Zhang P.

J Virol. 2018 Jun 13;92(13). pii: e00368-18. doi: 10.1128/JVI.00368-18. Print 2018 Jul 1.

40.

Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter.

Sorkina T, Ma S, Larsen MB, Watkins SC, Sorkin A.

Elife. 2018 Apr 9;7. pii: e32293. doi: 10.7554/eLife.32293.

41.

4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses.

Menk AV, Scharping NE, Rivadeneira DB, Calderon MJ, Watson MJ, Dunstane D, Watkins SC, Delgoffe GM.

J Exp Med. 2018 Apr 2;215(4):1091-1100. doi: 10.1084/jem.20171068. Epub 2018 Mar 6.

42.

Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking.

Perkins LA, Yan Q, Schmidt BF, Kolodieznyi D, Saurabh S, Larsen MB, Watkins SC, Kremer L, Bruchez MP.

Biochemistry. 2018 Feb 6;57(5):861-871. doi: 10.1021/acs.biochem.7b01135. Epub 2018 Jan 16.

PMID:
29283245
43.

EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo.

Pinilla-Macua I, Grassart A, Duvvuri U, Watkins SC, Sorkin A.

Elife. 2017 Dec 21;6. pii: e31993. doi: 10.7554/eLife.31993.

44.

Cerebral microcirculatory alterations and the no-reflow phenomenon in vivo after experimental pediatric cardiac arrest.

Li L, Poloyac SM, Watkins SC, St Croix CM, Alexander H, Gibson GA, Loughran PA, Kirisci L, Clark RS, Kochanek PM, Vazquez AL, Manole MD.

J Cereb Blood Flow Metab. 2019 May;39(5):913-925. doi: 10.1177/0271678X17744717. Epub 2017 Dec 1.

PMID:
29192562
45.

14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in TC2 and CD8+ lymphocytes from patients with scleroderma.

Cascio S, Medsger TA Jr, Hawse WF, Watkins SC, Milcarek C, Moreland LW, Lafyatis RA, Fuschiotti P.

J Allergy Clin Immunol. 2018 Jul;142(1):109-119.e6. doi: 10.1016/j.jaci.2017.10.029. Epub 2017 Nov 15.

46.

PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1.

Liu L, Kong M, Gassman NR, Freudenthal BD, Prasad R, Zhen S, Watkins SC, Wilson SH, Van Houten B.

Nucleic Acids Res. 2017 Dec 15;45(22):12834-12847. doi: 10.1093/nar/gkx1047.

47.

Interplay between Keratinocytes and Myeloid Cells Drives Dengue Virus Spread in Human Skin.

Duangkhae P, Erdos G, Ryman KD, Watkins SC, Falo LD Jr, Marques ETA Jr, Barratt-Boyes SM.

J Invest Dermatol. 2018 Mar;138(3):618-626. doi: 10.1016/j.jid.2017.10.018. Epub 2017 Oct 26.

48.

Monomer sequence in PLGA microparticles: Effects on acidic microclimates and in vivo inflammatory response.

Washington MA, Balmert SC, Fedorchak MV, Little SR, Watkins SC, Meyer TY.

Acta Biomater. 2018 Jan;65:259-271. doi: 10.1016/j.actbio.2017.10.043. Epub 2017 Oct 31.

PMID:
29101019
49.

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE.

Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044.

50.

Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans.

Rudich P, Snoznik C, Watkins SC, Monaghan J, Pandey UB, Lamitina ST.

Hum Mol Genet. 2017 Dec 15;26(24):4916-4928. doi: 10.1093/hmg/ddx372.

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