Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51


Interactions and activities of factors involved in the late stages of human 18S rRNA maturation.

Sloan KE, Knox AA, Wells GR, Schneider C, Watkins NJ.

RNA Biol. 2019 Feb;16(2):196-210. doi: 10.1080/15476286.2018.1564467. Epub 2019 Jan 13.


Three-Dimensional CeO2 Woodpile Nanostructures To Enhance Performance of Enzymatic Glucose Biosensors.

Zhou Y, Uzun SD, Watkins NJ, Li S, Li W, Briseno AL, Carter KR, Watkins JJ.

ACS Appl Mater Interfaces. 2019 Jan 16;11(2):1821-1828. doi: 10.1021/acsami.8b16985. Epub 2019 Jan 4.


Unusual C΄/D΄ motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region.

van Nues RW, Watkins NJ.

Nucleic Acids Res. 2017 Feb 28;45(4):2016-2028. doi: 10.1093/nar/gkw842.


The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain.

Wells GR, Weichmann F, Sloan KE, Colvin D, Watkins NJ, Schneider C.

Nucleic Acids Res. 2017 May 5;45(8):4796-4809. doi: 10.1093/nar/gkw1344.


The importance of ribosome production, and the 5S RNP-MDM2 pathway, in health and disease.

Pelava A, Schneider C, Watkins NJ.

Biochem Soc Trans. 2016 Aug 15;44(4):1086-90. doi: 10.1042/BST20160106. Review.


The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans.

Wells GR, Weichmann F, Colvin D, Sloan KE, Kudla G, Tollervey D, Watkins NJ, Schneider C.

Nucleic Acids Res. 2016 Oct 14;44(18):9016. Epub 2016 Jul 14. No abstract available.


The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans.

Wells GR, Weichmann F, Colvin D, Sloan KE, Kudla G, Tollervey D, Watkins NJ, Schneider C.

Nucleic Acids Res. 2016 Jun 20;44(11):5399-409. doi: 10.1093/nar/gkw213. Epub 2016 Mar 31. Erratum in: Nucleic Acids Res. 2016 Oct 14;44(18):9016.


The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21.

Sloan KE, Leisegang MS, Doebele C, Ramírez AS, Simm S, Safferthal C, Kretschmer J, Schorge T, Markoutsa S, Haag S, Karas M, Ebersberger I, Schleiff E, Watkins NJ, Bohnsack MT.

Nucleic Acids Res. 2015 Jan;43(1):553-64. doi: 10.1093/nar/gku1291. Epub 2014 Dec 4.


Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery.

Leung E, Schneider C, Yan F, Mohi-El-Din H, Kudla G, Tuck A, Wlotzka W, Doronina VA, Bartley R, Watkins NJ, Tollervey D, Brown JD.

Nucleic Acids Res. 2014;42(16):10698-710. doi: 10.1093/nar/gku761. Epub 2014 Aug 26.


The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.

Sloan KE, Bohnsack MT, Schneider C, Watkins NJ.

RNA. 2014 Apr;20(4):540-50. doi: 10.1261/rna.043471.113. Epub 2014 Feb 18.


The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress.

Sloan KE, Bohnsack MT, Watkins NJ.

Cell Rep. 2013 Oct 17;5(1):237-47. doi: 10.1016/j.celrep.2013.08.049. Epub 2013 Oct 10.


Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing.

Sloan KE, Mattijssen S, Lebaron S, Tollervey D, Pruijn GJ, Watkins NJ.

J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.


Comparison of the yeast and human nuclear exosome complexes.

Sloan KE, Schneider C, Watkins NJ.

Biochem Soc Trans. 2012 Aug;40(4):850-5. doi: 10.1042/BST20120061. Review.


Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits.

Lebaron S, Schneider C, van Nues RW, Swiatkowska A, Walsh D, Böttcher B, Granneman S, Watkins NJ, Tollervey D.

Nat Struct Mol Biol. 2012 Aug;19(8):744-53. doi: 10.1038/nsmb.2308. Epub 2012 Jul 1.


Nucleolar disruption leads to the spatial separation of key 18S rRNA processing factors.

Turner AJ, Knox AA, Watkins NJ.

RNA Biol. 2012 Feb;9(2):175-86. doi: 10.4161/rna.18811. Epub 2012 Feb 1.


The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA.

Watkins NJ, Bohnsack MT.

Wiley Interdiscip Rev RNA. 2012 May-Jun;3(3):397-414. doi: 10.1002/wrna.117. Epub 2011 Nov 7. Review.


Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing.

van Nues RW, Granneman S, Kudla G, Sloan KE, Chicken M, Tollervey D, Watkins NJ.

EMBO J. 2011 May 10;30(12):2420-30. doi: 10.1038/emboj.2011.148.


A weak C' box renders U3 snoRNA levels dependent on hU3-55K binding.

Knox AA, McKeegan KS, Debieux CM, Traynor A, Richardson H, Watkins NJ.

Mol Cell Biol. 2011 Jun;31(12):2404-12. doi: 10.1128/MCB.05067-11. Epub 2011 Apr 19.


The spatial-functional coupling of box C/D and C'/D' RNPs is an evolutionarily conserved feature of the eukaryotic box C/D snoRNP nucleotide modification complex.

Qu G, van Nues RW, Watkins NJ, Maxwell ES.

Mol Cell Biol. 2011 Jan;31(2):365-74. doi: 10.1128/MCB.00918-10. Epub 2010 Nov 1.


A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation.

Ghalei H, Hsiao HH, Urlaub H, Wahl MC, Watkins NJ.

RNA. 2010 Dec;16(12):2341-8. doi: 10.1261/rna.2380410. Epub 2010 Oct 20.


The enteropathogenic E. coli effector EspF targets and disrupts the nucleolus by a process regulated by mitochondrial dysfunction.

Dean P, Scott JA, Knox AA, Quitard S, Watkins NJ, Kenny B.

PLoS Pathog. 2010 Jun 24;6(6):e1000961. doi: 10.1371/journal.ppat.1000961.


Evidence that the AAA+ proteins TIP48 and TIP49 bridge interactions between 15.5K and the related NOP56 and NOP58 proteins during box C/D snoRNP biogenesis.

McKeegan KS, Debieux CM, Watkins NJ.

Mol Cell Biol. 2009 Sep;29(18):4971-81. doi: 10.1128/MCB.00752-09. Epub 2009 Jul 20.


A novel small-subunit processome assembly intermediate that contains the U3 snoRNP, nucleolin, RRP5, and DBP4.

Turner AJ, Knox AA, Prieto JL, McStay B, Watkins NJ.

Mol Cell Biol. 2009 Jun;29(11):3007-17. doi: 10.1128/MCB.00029-09. Epub 2009 Mar 30.


Minor spliceosome components are predominantly localized in the nucleus.

Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Perälä N, Nymark M, Turunen JJ, Lührmann R, Frilander MJ.

Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8655-60. doi: 10.1073/pnas.0803646105. Epub 2008 Jun 16.


Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis.

Watkins NJ, Lemm I, Lührmann R.

Mol Cell Biol. 2007 Oct;27(20):7018-27. Epub 2007 Aug 20.


A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly.

McKeegan KS, Debieux CM, Boulon S, Bertrand E, Watkins NJ.

Mol Cell Biol. 2007 Oct;27(19):6782-93. Epub 2007 Jul 16.


Fiber optic light collection system for scanning-tunneling-microscope-induced light emission.

Watkins NJ, Long JP, Kafafi ZH, Mäkinen AJ.

Rev Sci Instrum. 2007 May;78(5):053707.


Sexithiophene adlayer growth on vicinal gold surfaces.

Mäkinen AJ, Long JP, Watkins NJ, Kafafi ZH.

J Phys Chem B. 2005 Mar 31;109(12):5790-5.


Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies.

Lemm I, Girard C, Kuhn AN, Watkins NJ, Schneider M, Bordonné R, Lührmann R.

Mol Biol Cell. 2006 Jul;17(7):3221-31. Epub 2006 May 10.


Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex.

Watkins NJ, Lemm I, Ingelfinger D, Schneider C, Hossbach M, Urlaub H, Lührmann R.

Mol Cell. 2004 Dec 3;16(5):789-98.


Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP.

Granneman S, Vogelzangs J, Lührmann R, van Venrooij WJ, Pruijn GJ, Watkins NJ.

Mol Cell Biol. 2004 Oct;24(19):8600-10.


Morphology and current-voltage characteristics of nanostructured pentacene thin films probed by atomic force microscopy.

Zorba S, Le QT, Watkins NJ, Yan L, Gao Y.

J Nanosci Nanotechnol. 2001 Sep;1(3):317-21.


The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro.

Granneman S, Pruijn GJ, Horstman W, van Venrooij WJ, Luhrmann R, Watkins NJ.

J Biol Chem. 2002 Dec 13;277(50):48490-500. Epub 2002 Oct 14.


A common core RNP structure shared between the small nucleoar box C/D RNPs and the spliceosomal U4 snRNP.

Watkins NJ, Ségault V, Charpentier B, Nottrott S, Fabrizio P, Bachi A, Wilm M, Rosbash M, Branlant C, Lührmann R.

Cell. 2000 Oct 27;103(3):457-66.


Processing of vertebrate box C/D small nucleolar RNAs in plant cells.

Leader DJ, Clark GP, Boag J, Watters JA, Simpson CG, Watkins NJ, Maxwell ES, Brown JW.

Eur J Biochem. 1998 Apr 1;253(1):154-60.


Coating of human decay accelerating factor (hDAF) onto medical devices to improve biocompatibility.

Watkins NJ, Braidley P, Bray CJ, Savill CM, White DJ.

Immunopharmacology. 1997 Dec;38(1-2):111-8.


Functional redundancy of promoter elements ensures efficient transcription of the human 7SK gene in vivo.

Boyd DC, Turner PC, Watkins NJ, Gerster T, Murphy S.

J Mol Biol. 1995 Nov 10;253(5):677-90.


Calcium and the generation of plant form.

Knight MR, Knight H, Watkins NJ.

Philos Trans R Soc Lond B Biol Sci. 1995 Oct 30;350(1331):83-6. Review.


The Xenopus U7 snRNA-encoding gene has an unusually compact structure.

Watkins NJ, Phillips SC, Turner PC.

Gene. 1992 Oct 21;120(2):271-6.


The U7 small nuclear RNA genes of Xenopus borealis.

Watkins NJ, Phillips SC, Turner PC.

Biochem Soc Trans. 1992 Aug;20(3):301S. No abstract available.


Supplemental Content

Loading ...
Support Center