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Problem-solving training: assessing the feasibility and acceptability of delivering and evaluating a problem-solving training model for front-line prison staff and prisoners who self-harm.

Perry A, Waterman MG, House A, Wright-Hughes A, Greenhalgh J, Farrin A, Richardson G, Hopton AK, Wright N.

BMJ Open. 2019 Oct 3;9(10):e026095. doi: 10.1136/bmjopen-2018-026095.


Benchmarking of alignment-free sequence comparison methods.

Zielezinski A, Girgis HZ, Bernard G, Leimeister CA, Tang K, Dencker T, Lau AK, Röhling S, Choi JJ, Waterman MS, Comin M, Kim SH, Vinga S, Almeida JS, Chan CX, James BT, Sun F, Morgenstern B, Karlowski WM.

Genome Biol. 2019 Jul 25;20(1):144. doi: 10.1186/s13059-019-1755-7.


Assessing evidence quality in research reporting neurocognitive outcomes following paediatric temporal lobe surgery for epilepsy.

Flint AE, Waterman MG, Siddell P, Houston AL, Vadlamani G, Chumas P, Morrall MCHJ.

Epilepsy Res. 2019 Aug;154:116-123. doi: 10.1016/j.eplepsyres.2019.03.013. Epub 2019 Mar 30. Review.


Thiopurine hepatotoxicity can mimic intrahepatic cholestasis of pregnancy.

Nasser R, Kurnik D, Lurie Y, Nassar L, Yaacob A, Veitsman E, Waterman M, Saadi T.

Clin Res Hepatol Gastroenterol. 2019 May 17. pii: S2210-7401(19)30094-4. doi: 10.1016/j.clinre.2019.04.004. [Epub ahead of print] No abstract available.


A new statistic for efficient detection of repetitive sequences.

Chen S, Chen Y, Sun F, Waterman MS, Zhang X.

Bioinformatics. 2019 Nov 1;35(22):4596-4606. doi: 10.1093/bioinformatics/btz262.


Duration of β-adrenoceptor blockade associated with once-daily oral administration of atenolol in healthy dogs.

Waterman MI, Abbott JA, De Rezende AE, Wilcke JR.

Am J Vet Res. 2019 Mar;80(3):270-274. doi: 10.2460/ajvr.80.3.270.


LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells.

Morgan RG, Ridsdale J, Payne M, Heesom KJ, Wilson MC, Davidson A, Greenhough A, Davies S, Williams AC, Blair A, Waterman ML, Tonks A, Darley RL.

Haematologica. 2019 Jul;104(7):1365-1377. doi: 10.3324/haematol.2018.202846. Epub 2019 Jan 10.


Photoprotection enhanced by red cell wall pigments in three East Antarctic mosses.

Waterman MJ, Bramley-Alves J, Miller RE, Keller PA, Robinson SA.

Biol Res. 2018 Nov 21;51(1):49. doi: 10.1186/s40659-018-0196-1.


Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51.

Hargrove TY, Wawrzak Z, Fisher PM, Child SA, Nes WD, Guengerich FP, Waterman MR, Lepesheva GI.

J Biol Chem. 2018 Dec 14;293(50):19344-19353. doi: 10.1074/jbc.RA118.005850. Epub 2018 Oct 16.


Effectiveness and safety of vedolizumab for maintenance treatment in inflammatory bowel disease-The Israeli real world experience.

Kopylov U, Avni-Biron I, Ron Y, Koslowsky B, Waterman M, Daher S, Ungar B, Schwartz D, Zittan E, Openhaim M, Yanai H, Maharshak N, Bar Gil Shitrit A, Naftali T, Eliakim R, Chowers Y, Ben-Horin S, Dotan I.

Dig Liver Dis. 2019 Jan;51(1):68-74. doi: 10.1016/j.dld.2018.07.040. Epub 2018 Aug 10.


Effects of financial incentives and cessation of thinning on prevalence of Campylobacter: a longitudinal monitoring study on commercial broiler farms in the UK.

Higham LE, Scott C, Akehurst K, Dring D, Parnham A, Waterman M, Bright A.

Vet Rec. 2018 Nov 17;183(19):595. doi: 10.1136/vr.104823. Epub 2018 Aug 31.


An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder.

Werling DM, Brand H, An JY, Stone MR, Zhu L, Glessner JT, Collins RL, Dong S, Layer RM, Markenscoff-Papadimitriou E, Farrell A, Schwartz GB, Wang HZ, Currall BB, Zhao X, Dea J, Duhn C, Erdman CA, Gilson MC, Yadav R, Handsaker RE, Kashin S, Klei L, Mandell JD, Nowakowski TJ, Liu Y, Pochareddy S, Smith L, Walker MF, Waterman MJ, He X, Kriegstein AR, Rubenstein JL, Sestan N, McCarroll SA, Neale BM, Coon H, Willsey AJ, Buxbaum JD, Daly MJ, State MW, Quinlan AR, Marth GT, Roeder K, Devlin B, Talkowski ME, Sanders SJ.

Nat Genet. 2018 Apr 26;50(5):727-736. doi: 10.1038/s41588-018-0107-y.


CYP51 as drug targets for fungi and protozoan parasites: past, present and future.

Lepesheva GI, Friggeri L, Waterman MR.

Parasitology. 2018 Dec;145(14):1820-1836. doi: 10.1017/S0031182018000562. Epub 2018 Apr 12. Review.


Cell-centred meta-analysis reveals baseline predictors of anti-TNFα non-response in biopsy and blood of patients with IBD.

Gaujoux R, Starosvetsky E, Maimon N, Vallania F, Bar-Yoseph H, Pressman S, Weisshof R, Goren I, Rabinowitz K, Waterman M, Yanai H, Dotan I, Sabo E, Chowers Y, Khatri P, Shen-Orr SS; Israeli IBD research Network (IIRN).

Gut. 2019 Apr;68(4):604-614. doi: 10.1136/gutjnl-2017-315494. Epub 2018 Apr 4.


TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency.

Sierra RA, Hoverter NP, Ramirez RN, Vuong LM, Mortazavi A, Merrill BJ, Waterman ML, Donovan PJ.

Development. 2018 Feb 23;145(4). pii: dev161075. doi: 10.1242/dev.161075.


Association of Vedolizumab Level, Anti-Drug Antibodies, and α4β7 Occupancy With Response in Patients With Inflammatory Bowel Diseases.

Ungar B, Kopylov U, Yavzori M, Fudim E, Picard O, Lahat A, Coscas D, Waterman M, Haj-Natour O, Orbach-Zingboim N, Mao R, Chen M, Chowers Y, Eliakim R, Ben-Horin S.

Clin Gastroenterol Hepatol. 2018 May;16(5):697-705.e7. doi: 10.1016/j.cgh.2017.11.050. Epub 2017 Dec 7.


Generalized correlation measure using count statistics for gene expression data with ordered samples.

Wang YXR, Liu K, Theusch E, Rotter JI, Medina MW, Waterman MS, Huang H, Stegle O.

Bioinformatics. 2018 Feb 15;34(4):617-624. doi: 10.1093/bioinformatics/btx641.


Neuropsychological outcomes following paediatric temporal lobe surgery for epilepsies: Evidence from a systematic review.

Flint AE, Waterman M, Bowmer G, Vadlamani G, Chumas P, Morrall MCHJ.

Seizure. 2017 Nov;52:89-116. doi: 10.1016/j.seizure.2017.09.011. Epub 2017 Sep 19. Review.


Optimal choice of word length when comparing two Markov sequences using a χ 2-statistic.

Bai X, Tang K, Ren J, Waterman M, Sun F.

BMC Genomics. 2017 Oct 3;18(Suppl 6):732. doi: 10.1186/s12864-017-4020-z.


Antarctic Moss Biflavonoids Show High Antioxidant and Ultraviolet-Screening Activity.

Waterman MJ, Nugraha AS, Hendra R, Ball GE, Robinson SA, Keller PA.

J Nat Prod. 2017 Aug 25;80(8):2224-2231. doi: 10.1021/acs.jnatprod.7b00085. Epub 2017 Aug 7.


Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy.

Lyou Y, Habowski AN, Chen GT, Waterman ML.

Br J Pharmacol. 2017 Dec;174(24):4589-4599. doi: 10.1111/bph.13963. Epub 2017 Aug 24. Review.


Impact of Infliximab and Cyclosporine on the Risk of Colectomy in Hospitalized Patients with Ulcerative Colitis Complicated by Cytomegalovirus-A Multicenter Retrospective Study.

Kopylov U, Papamichael K, Katsanos K, Waterman M, Bar-Gil Shitrit A, Boysen T, Portela F, Peixoto A, Szilagyi A, Silva M, Maconi G, Har-Noy O, Bossuyt P, Mantzaris G, Barreiro de Acosta M, Chaparro M, Christodoulou DK, Eliakim R, Rahier JF, Magro F, Drobne D, Ferrante M, Sonnenberg E, Siegmund B, Muls V, Thurm T, Yanai H, Dotan I, Raine T, Levin A, Israeli E, Ghalim F, Carbonnel F, Vermeire S, Ben-Horin S, Roblin X.

Inflamm Bowel Dis. 2017 Sep;23(9):1605-1613. doi: 10.1097/MIB.0000000000001160.


Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia.

Wang C, Pallan PS, Zhang W, Lei L, Yoshimoto FK, Waterman MR, Egli M, Guengerich FP.

J Biol Chem. 2017 Jun 30;292(26):10767-10778. doi: 10.1074/jbc.M117.792465. Epub 2017 May 24.


CAFE: aCcelerated Alignment-FrEe sequence analysis.

Lu YY, Tang K, Ren J, Fuhrman JA, Waterman MS, Sun F.

Nucleic Acids Res. 2017 Jul 3;45(W1):W554-W559. doi: 10.1093/nar/gkx351.


Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer.

Lee M, Chen GT, Puttock E, Wang K, Edwards RA, Waterman ML, Lowengrub J.

Mol Syst Biol. 2017 Feb 9;13(2):912. doi: 10.15252/msb.20167386.


Efficacy and Safety of Vedolizumab for Induction of Remission in Inflammatory Bowel Disease-the Israeli Real-World Experience.

Kopylov U, Ron Y, Avni-Biron I, Koslowsky B, Waterman M, Daher S, Ungar B, Yanai H, Maharshak N, Ben-Bassat O, Lichtenstein L, Bar-Gil Shitrit A, Israeli E, Schwartz D, Zittan E, Eliakim R, Chowers Y, Ben-Horin S, Dotan I.

Inflamm Bowel Dis. 2017 Mar;23(3):404-408. doi: 10.1097/MIB.0000000000001039.


The association of the MTHFR C677T polymorphism with inflammatory bowel diseases in the Israeli Jewish population: An example of genetic heterogeneity.

Karban A, Feldman T, Waterman M, Leiba R, Efrati E.

Medicine (Baltimore). 2016 Dec;95(51):e5611. doi: 10.1097/MD.0000000000005611.


Men Presenting With Sexual Thoughts of Children or Coercion: Flights of Fancy or Plans for Crime?

Turner-Moore T, Waterman M.

J Sex Med. 2017 Jan;14(1):113-124. doi: 10.1016/j.jsxm.2016.11.003. Epub 2016 Nov 30. Erratum in: J Sex Med. 2017 Mar;14(3):473.


The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies.

Redin C, Brand H, Collins RL, Kammin T, Mitchell E, Hodge JC, Hanscom C, Pillalamarri V, Seabra CM, Abbott MA, Abdul-Rahman OA, Aberg E, Adley R, Alcaraz-Estrada SL, Alkuraya FS, An Y, Anderson MA, Antolik C, Anyane-Yeboa K, Atkin JF, Bartell T, Bernstein JA, Beyer E, Blumenthal I, Bongers EM, Brilstra EH, Brown CW, Brüggenwirth HT, Callewaert B, Chiang C, Corning K, Cox H, Cuppen E, Currall BB, Cushing T, David D, Deardorff MA, Dheedene A, D'Hooghe M, de Vries BB, Earl DL, Ferguson HL, Fisher H, FitzPatrick DR, Gerrol P, Giachino D, Glessner JT, Gliem T, Grady M, Graham BH, Griffis C, Gripp KW, Gropman AL, Hanson-Kahn A, Harris DJ, Hayden MA, Hill R, Hochstenbach R, Hoffman JD, Hopkin RJ, Hubshman MW, Innes AM, Irons M, Irving M, Jacobsen JC, Janssens S, Jewett T, Johnson JP, Jongmans MC, Kahler SG, Koolen DA, Korzelius J, Kroisel PM, Lacassie Y, Lawless W, Lemyre E, Leppig K, Levin AV, Li H, Li H, Liao EC, Lim C, Lose EJ, Lucente D, Macera MJ, Manavalan P, Mandrile G, Marcelis CL, Margolin L, Mason T, Masser-Frye D, McClellan MW, Mendoza CJ, Menten B, Middelkamp S, Mikami LR, Moe E, Mohammed S, Mononen T, Mortenson ME, Moya G, Nieuwint AW, Ordulu Z, Parkash S, Pauker SP, Pereira S, Perrin D, Phelan K, Aguilar RE, Poddighe PJ, Pregno G, Raskin S, Reis L, Rhead W, Rita D, Renkens I, Roelens F, Ruliera J, Rump P, Schilit SL, Shaheen R, Sparkes R, Spiegel E, Stevens B, Stone MR, Tagoe J, Thakuria JV, van Bon BW, van de Kamp J, van Der Burgt I, van Essen T, van Ravenswaaij-Arts CM, van Roosmalen MJ, Vergult S, Volker-Touw CM, Warburton DP, Waterman MJ, Wiley S, Wilson A, Yerena-de Vega MC, Zori RT, Levy B, Brunner HG, de Leeuw N, Kloosterman WP, Thorland EC, Morton CC, Gusella JF, Talkowski ME.

Nat Genet. 2017 Jan;49(1):36-45. doi: 10.1038/ng.3720. Epub 2016 Nov 14.


Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer.

Sprowl-Tanio S, Habowski AN, Pate KT, McQuade MM, Wang K, Edwards RA, Grun F, Lyou Y, Waterman ML.

Cancer Metab. 2016 Oct 3;4:20. eCollection 2016.


Genetic Predictors of Benign Course of Ulcerative Colitis-A North American Inflammatory Bowel Disease Genetics Consortium Study.

Kopylov U, Boucher G, Waterman M, Rivers CR, Patel M, Cho JH, Colombel JF, Duerr RH, Binion D, McGovern DP, Schumm PP, Brant SR, Silverberg MS, Rioux JD, Bitton A.

Inflamm Bowel Dis. 2016 Oct;22(10):2311-6. doi: 10.1097/MIB.0000000000000913.


Prevention of Antidrug Antibody Formation to Infliximab in Crohn's Patients With Prior Failure of Thiopurines.

Bar-Yoseph H, Waterman M, Almog R, Billiet T, Vermeire S, Ungar B, Yanai H, Dotan I, Ben-Horin S, Chowers Y.

Clin Gastroenterol Hepatol. 2017 Jan;15(1):69-75. doi: 10.1016/j.cgh.2016.06.028. Epub 2016 Jul 9.


Is Super-Selective Superior?

Waterman M, Kurnik D, Chowers Y.

J Crohns Colitis. 2016 Oct;10(10):1129-31. doi: 10.1093/ecco-jcc/jjw128. Epub 2016 Jul 11. No abstract available.


Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design.

Hargrove TY, Friggeri L, Wawrzak Z, Sivakumaran S, Yazlovitskaya EM, Hiebert SW, Guengerich FP, Waterman MR, Lepesheva GI.

J Lipid Res. 2016 Aug;57(8):1552-63. doi: 10.1194/jlr.M069229. Epub 2016 Jun 16.


Recent Structural Insights into Cytochrome P450 Function.

Guengerich FP, Waterman MR, Egli M.

Trends Pharmacol Sci. 2016 Aug;37(8):625-640. doi: 10.1016/ Epub 2016 Jun 4. Review.


Anti-infliximab Antibodies with Neutralizing Capacity in Patients with Inflammatory Bowel Disease: Distinct Clinical Implications Revealed by a Novel Assay.

Weisshof R, Ungar B, Blatt A, Dahan A, Pressman S, Waterman M, Kopylov U, Ben-Horin S, Chowers Y.

Inflamm Bowel Dis. 2016 Jul;22(7):1655-61. doi: 10.1097/MIB.0000000000000797.


Associations between nonauditory hallucinations, dissociation, and childhood adversity in first-episode psychosis.

Longden E, House AO, Waterman MG.

J Trauma Dissociation. 2016 Oct-Dec;17(5):545-560. Epub 2016 Feb 25.


Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.

Goldstone JV, Sundaramoorthy M, Zhao B, Waterman MR, Stegeman JJ, Lamb DC.

Mol Phylogenet Evol. 2016 Jan;94(Pt B):676-687. doi: 10.1016/j.ympev.2015.09.012. Epub 2015 Oct 3.


Does self-certification reflect the cardiac health of UK sport divers?

St Leger Dowse M, Waterman MK, Penny CE, Smerdon GR.

Diving Hyperb Med. 2015 Sep;45(3):184-9.


Cancer: leaping the E-cadherin hurdle.

Chen GT, Waterman ML.

EMBO J. 2015 Sep 14;34(18):2307-9. doi: 10.15252/embj.201592757. Epub 2015 Aug 17. No abstract available.


Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.

Vuong LM, Chellappa K, Dhahbi JM, Deans JR, Fang B, Bolotin E, Titova NV, Hoverter NP, Spindler SR, Waterman ML, Sladek FM.

Mol Cell Biol. 2015 Oct;35(20):3471-90. doi: 10.1128/MCB.00030-15. Epub 2015 Aug 3.


Predictors of Outcome in Ulcerative Colitis.

Waterman M, Knight J, Dinani A, Xu W, Stempak JM, Croitoru K, Nguyen GC, Cohen Z, McLeod RS, Greenberg GR, Steinhart AH, Silverberg MS.

Inflamm Bowel Dis. 2015 Sep;21(9):2097-105. doi: 10.1097/MIB.0000000000000466.


Research Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia.

Pallan PS, Lei L, Wang C, Waterman MR, Guengerich FP, Egli M.

Mol Endocrinol. 2015 Sep;29(9):1375-84. doi: 10.1210/ME.2015-1127. Epub 2015 Jul 14.


Use of Biosimilars in Paediatric Inflammatory Bowel Disease: A Position Statement of the ESPGHAN Paediatric IBD Porto Group.

de Ridder L, Waterman M, Turner D, Bronsky J, Hauer AC, Dias JA, Strisciuglio C, Ruemmele FM, Levine A, Lionetti P; ESPGHAN Paediatric IBD Porto Group.

J Pediatr Gastroenterol Nutr. 2015 Oct;61(4):503-8. doi: 10.1097/MPG.0000000000000903.


VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.

Lepesheva GI, Hargrove TY, Rachakonda G, Wawrzak Z, Pomel S, Cojean S, Nde PN, Nes WD, Locuson CW, Calcutt MW, Waterman MR, Daniels JS, Loiseau PM, Villalta F.

J Infect Dis. 2015 Nov 1;212(9):1439-48. doi: 10.1093/infdis/jiv228. Epub 2015 Apr 15.



Pallan PS, Wang C, Lei L, Yoshimoto FK, Auchus RJ, Waterman MR, Guengerich FP, Egli M.

J Biol Chem. 2015 May 22;290(21):13128-43. doi: 10.1074/jbc.M115.646307. Epub 2015 Apr 8.


Activation of the Wnt/β-catenin signaling cascade after traumatic nerve injury.

Kurimoto S, Jung J, Tapadia M, Lengfeld J, Agalliu D, Waterman M, Mozaffar T, Gupta R.

Neuroscience. 2015 May 21;294:101-8. doi: 10.1016/j.neuroscience.2015.02.049. Epub 2015 Mar 3.


The co-occurrence of aggression and self-harm: systematic literature review.

O'Donnell O, House A, Waterman M.

J Affect Disord. 2015 Apr 1;175:325-50. doi: 10.1016/j.jad.2014.12.051. Epub 2014 Dec 29. Review.


Accuracy of capsule colonoscopy in detecting colorectal polyps in a screening population.

Rex DK, Adler SN, Aisenberg J, Burch WC Jr, Carretero C, Chowers Y, Fein SA, Fern SE, Fernandez-Urien Sainz I, Fich A, Gal E, Horlander JC Sr, Isaacs KL, Kariv R, Lahat A, Leung WK, Malik PR, Morgan D, Papageorgiou N, Romeo DP, Shah SS, Waterman M.

Gastroenterology. 2015 May;148(5):948-957.e2. doi: 10.1053/j.gastro.2015.01.025. Epub 2015 Jan 22.


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