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Items: 26

1.

Multiple Proteinopathies in Familial ALS Cases With Optineurin Mutations.

Ayaki T, Ito H, Komure O, Kamada M, Nakamura M, Wate R, Kusaka H, Yamaguchi Y, Li F, Kawakami H, Urushitani M, Takahashi R.

J Neuropathol Exp Neurol. 2018 Feb 1;77(2):128-138. doi: 10.1093/jnen/nlx109.

PMID:
29272468
2.

Zonisamide ameliorates levodopa-induced dyskinesia and reduces expression of striatal genes in Parkinson model rats.

Oki M, Kaneko S, Morise S, Takenouchi N, Hashizume T, Tsuge A, Nakamura M, Wate R, Kusaka H.

Neurosci Res. 2017 Sep;122:45-50. doi: 10.1016/j.neures.2017.04.003. Epub 2017 May 31.

PMID:
28577977
3.

Weight loss in the early stage of progressive supranuclear palsy.

Tsuge A, Kaneko S, Wate R, Oki M, Nagashima M, Asayama S, Nakamura M, Fujita K, Saito A, Takenouchi N, Kusaka H.

Brain Behav. 2016 Dec 5;7(2):e00616. doi: 10.1002/brb3.616. eCollection 2017 Feb.

4.

Early-onset Parkinson's Disease Associated with Chromosome 22q11.2 Deletion Syndrome.

Oki M, Hori S, Asayama S, Wate R, Kaneko S, Kusaka H.

Intern Med. 2016;55(3):303-5. doi: 10.2169/internalmedicine.55.5485. Epub 2016 Feb 1.

5.

Successful treatment of paroxysmal tonic spasms with topiramate in a patient with neuromyelitis optica.

Iida S, Nakamura M, Wate R, Kaneko S, Kusaka H.

Mult Scler Relat Disord. 2015 Sep;4(5):457-459. doi: 10.1016/j.msard.2015.07.011. Epub 2015 Jul 23.

PMID:
26346795
6.

An autopsy case of sporadic amyotrophic lateral sclerosis associated with the I113T SOD1 mutation.

Nakamura S, Wate R, Kaneko S, Ito H, Oki M, Tsuge A, Nagashima M, Asayama S, Fujita K, Nakamura M, Maruyama H, Kawakami H, Kusaka H.

Neuropathology. 2014 Feb;34(1):58-63. doi: 10.1111/neup.12049. Epub 2013 Jun 17.

PMID:
23773010
7.

Levodopa challenge test and (123) I-metaiodobenzylguanidine scintigraphy for diagnosing Parkinson's disease.

Asayama S, Wate R, Kaneko S, Asayama T, Oki M, Tsuge A, Nagashima M, Morita J, Nakamura S, Nakamura M, Nishii M, Fujita K, Saito A, Nakano S, Ito H, Kusaka H.

Acta Neurol Scand. 2013 Sep;128(3):160-5. doi: 10.1111/ane.12104. Epub 2013 Feb 15.

PMID:
23410225
8.

Activation of transforming growth factor-β/Smad signaling reduces aggregate formation of mislocalized TAR DNA-binding protein-43.

Nakamura M, Kaneko S, Ito H, Jiang S, Fujita K, Wate R, Nakano S, Fujisawa J, Kusaka H.

Neurodegener Dis. 2013;11(4):182-93. doi: 10.1159/000338151. Epub 2012 Jul 10.

PMID:
22797246
9.

Regionally different immunoreactivity for Smurf2 and pSmad2/3 in TDP-43-positive inclusions of amyotrophic lateral sclerosis.

Nakamura M, Kaneko S, Wate R, Asayama S, Nakamura Y, Fujita K, Ito H, Kusaka H.

Neuropathol Appl Neurobiol. 2013 Feb;39(2):144-56. doi: 10.1111/j.1365-2990.2012.01270.x.

PMID:
22435645
10.

Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation.

Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, Fujita K, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, Kaji R, Takahashi R, Kawakami H.

Acta Neuropathol. 2011 Aug;122(2):223-9. doi: 10.1007/s00401-011-0842-y. Epub 2011 Jun 5.

PMID:
21644038
11.

Myonuclear breakdown in sporadic inclusion body myositis is accompanied by DNA double strand breaks.

Nishii M, Nakano S, Nakamura S, Wate R, Shinde A, Kaneko S, Kusaka H.

Neuromuscul Disord. 2011 May;21(5):345-52. doi: 10.1016/j.nmd.2011.02.004. Epub 2011 Feb 24.

PMID:
21353553
12.

Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease.

Ito H, Fujita K, Nakamura M, Wate R, Kaneko S, Sasaki S, Yamane K, Suzuki N, Aoki M, Shibata N, Togashi S, Kawata A, Mochizuki Y, Mizutani T, Maruyama H, Hirano A, Takahashi R, Kawakami H, Kusaka H.

Acta Neuropathol. 2011 Apr;121(4):555-7. doi: 10.1007/s00401-011-0809-z. Epub 2011 Feb 17. No abstract available.

PMID:
21327942
13.

Smad ubiquitination regulatory factor-2 in progressive supranuclear palsy.

Nakamura M, Ito H, Nakamura Y, Wate R, Kaneko S, Nakano S, Matsumoto S, Kusaka H.

Neuropathol Appl Neurobiol. 2011 Apr;37(3):307-14. doi: 10.1111/j.1365-2990.2010.01120.x.

PMID:
20819168
14.

[A case of cerebellar syndrome associated with HIV infection].

Nakamura S, Wate R, Shinde A, Asayama S, Nakano S, Kusaka H.

Rinsho Shinkeigaku. 2009 Oct;49(10):651-5. Japanese.

PMID:
19999147
15.

Nuclear contour irregularity and abnormal transporter protein distribution in anterior horn cells in amyotrophic lateral sclerosis.

Kinoshita Y, Ito H, Hirano A, Fujita K, Wate R, Nakamura M, Kaneko S, Nakano S, Kusaka H.

J Neuropathol Exp Neurol. 2009 Nov;68(11):1184-92. doi: 10.1097/NEN.0b013e3181bc3bec.

PMID:
19816199
16.

Intra-bone marrow-bone marrow transplantation slows disease progression and prolongs survival in G93A mutant SOD1 transgenic mice, an animal model mouse for amyotrophic lateral sclerosis.

Ohnishi S, Ito H, Suzuki Y, Adachi Y, Wate R, Zhang J, Nakano S, Kusaka H, Ikehara S.

Brain Res. 2009 Nov 3;1296:216-24. doi: 10.1016/j.brainres.2009.08.012. Epub 2009 Aug 15.

PMID:
19686706
17.

Screening for TARDBP mutations in Japanese familial amyotrophic lateral sclerosis.

Kamada M, Maruyama H, Tanaka E, Morino H, Wate R, Ito H, Kusaka H, Kawano Y, Miki T, Nodera H, Izumi Y, Kaji R, Kawakami H.

J Neurol Sci. 2009 Sep 15;284(1-2):69-71. doi: 10.1016/j.jns.2009.04.017. Epub 2009 May 2.

PMID:
19411082
18.

The first Japanese patient with variant Creutzfeldt-Jakob disease (vCJD).

Shinde A, Kunieda T, Kinoshita Y, Wate R, Nakano S, Ito H, Yamada M, Kitamoto T, Nakamura Y, Matsumoto S, Kusaka H.

Neuropathology. 2009 Dec;29(6):713-9. doi: 10.1111/j.1440-1789.2009.01006.x. Epub 2009 Mar 3.

PMID:
19389077
19.

Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice.

Ito H, Wate R, Zhang J, Ohnishi S, Kaneko S, Ito H, Nakano S, Kusaka H.

Exp Neurol. 2008 Oct;213(2):448-55. doi: 10.1016/j.expneurol.2008.07.017. Epub 2008 Jul 31.

PMID:
18718468
20.

Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease.

Fujita K, Ito H, Nakano S, Kinoshita Y, Wate R, Kusaka H.

Acta Neuropathol. 2008 Oct;116(4):439-45. doi: 10.1007/s00401-008-0415-x. Epub 2008 Jul 19.

PMID:
18642007
21.

Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model.

Nakamura M, Ito H, Wate R, Nakano S, Hirano A, Kusaka H.

Acta Neuropathol. 2008 Mar;115(3):327-34. doi: 10.1007/s00401-007-0337-z. Epub 2008 Jan 22.

PMID:
18210139
22.

Diagnostic clues and more from photographs.

Hirano A, Wate R.

Neuropathology. 2007 Feb;27(1):1-9. Review.

PMID:
17319278
23.

Clinicopathologic investigation of a family with expanded SCA8 CTA/CTG repeats.

Ito H, Kawakami H, Wate R, Matsumoto S, Imai T, Hirano A, Kusaka H.

Neurology. 2006 Oct 24;67(8):1479-81.

PMID:
17060579
24.

Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosis.

Zhang J, Ito H, Wate R, Ohnishi S, Nakano S, Kusaka H.

Acta Neuropathol. 2006 Dec;112(6):673-80. Epub 2006 Sep 7.

PMID:
16957927
25.

Expression of an endoplasmic reticulum-resident chaperone, glucose-regulated stress protein 78, in the spinal cord of a mouse model of amyotrophic lateral sclerosis.

Wate R, Ito H, Zhang JH, Ohnishi S, Nakano S, Kusaka H.

Acta Neuropathol. 2005 Dec;110(6):557-62. Epub 2005 Oct 18.

PMID:
16231159
26.

Radio-sensitivity of the cells from amyotrophic lateral sclerosis model mice transfected with human mutant SOD1.

Wate R, Takahashi S, Ito H, Kusaka H, Kubota Y, Suetomi K, Sato H, Okayasu R.

J Radiat Res. 2005 Mar;46(1):67-73.

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