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Items: 1 to 50 of 57

1.

An observation: role of the M.D., Ph.D. in science.

Watanabe PG.

Toxicol Sci. 1999 Jun;49(2):165. No abstract available.

PMID:
10416261
2.

Toxicologists: have we been honest with the public?

Watanabe PG.

Toxicol Sci. 1998 Feb;41(2):153-4. No abstract available.

PMID:
9520349
3.

Changing Times Require Changing Behavior

Watanabe PG.

Fundam Appl Toxicol. 1997 Jun;37(2):101. No abstract available.

PMID:
9242581
4.
5.

Metabolism and disposition of ethylene carbonate in male Fischer 344 rats.

Hanley TR Jr, Schumann AM, Langvardt PW, Rusek TF, Watanabe PG.

Toxicol Appl Pharmacol. 1989 Aug;100(1):24-31.

PMID:
2763299
6.

Toxicokinetics in the evaluation of toxicity data.

Watanabe PG, Schumann AM, Reitz RH.

Regul Toxicol Pharmacol. 1988 Dec;8(4):408-13.

PMID:
3222482
7.

Assessment of cell cycle duration on the incidence of sister chromatid exchanges in somatic and spermatogonial cells of the rat.

Sinha AK, Linscombe VA, Gollapudi BB, Zempel JA, Watanabe PG.

Cancer Res. 1988 Nov 1;48(21):5953-5.

8.

Mechanistic considerations in carcinogenic risk estimation.

Watanabe PG, Reitz RH, Schumann AM.

J Toxicol Clin Exp. 1988 Jan-Feb;8(1):11-9. No abstract available.

PMID:
3373442
9.

Research strategy in industrial toxicology.

Watanabe PG, Fox TR, Reitz RH, Schumann AM, Andersen ME.

J Toxicol Sci. 1987 May;12(2):223-33.

10.

Activation of a cellular proto-oncogene in spontaneous liver tumor tissue of the B6C3F1 mouse.

Fox TR, Schumann AM, Watanabe PG.

Arch Toxicol Suppl. 1987;10:217-27.

PMID:
3472499
11.

Effect of food and water deprivation on the parameters of the mouse bone marrow micronucleus test.

Gollapudi BB, Bruce RJ, Linscombe VA, Watanabe PG, Sinha AK.

Mutat Res. 1986 Feb;173(2):121-5.

PMID:
3945239
12.

The role of pharmacokinetics in risk assessment.

Reitz RH, Fox TR, Watanabe PG.

Basic Life Sci. 1986;38:499-507. No abstract available.

PMID:
3741342
13.

Detection of a cellular oncogene in spontaneous liver tumors of B6C3F1 mice.

Fox TR, Watanabe PG.

Science. 1985 May 3;228(4699):596-7.

PMID:
3983645
14.

Measurement of solid feed consumption patterns in neonatal rats by 141Ce-radiolabeled microspheres.

Hanley TR Jr, Watanabe PG.

Toxicol Appl Pharmacol. 1985 Mar 15;77(3):496-500.

PMID:
3975917
15.

Biochemical factors involved in the effects of orthophenylphenol (OPP) and sodium orthophenylphenate (SOPP) on the urinary tract of male F344 rats.

Reitz RH, Fox TR, Quast JF, Hermann EA, Watanabe PG.

Toxicol Appl Pharmacol. 1984 Apr;73(2):345-9.

PMID:
6710533
16.

Assessment of genotoxic potential of ethylenediamine: in vitro and in vivo studies.

Slesinski RS, Guzzie PJ, Hengler WC, Watanabe PG, Woodside MD, Yang RS.

Mutat Res. 1983 Dec;124(3-4):299-314.

PMID:
6656830
17.

Relevance of experimental studies to human risk.

Dietz FK, Ramsey JC, Watanabe PG.

Environ Health Perspect. 1983 Oct;52:9-14.

18.
19.

Molecular mechanisms involved in the toxicity of orthophenylphenol and its sodium salt.

Reitz RH, Fox TR, Quast JF, Hermann EA, Watanabe PG.

Chem Biol Interact. 1983 Jan;43(1):99-119. No abstract available.

PMID:
6821879
20.

Importance of non-genetic mechanisms in carcinogenicity.

Reitz RH, Watanabe PG.

Dev Toxicol Environ Sci. 1983;11:163-72.

PMID:
6677453
21.

Evaluation of ELISA for detecting in vivo chemical immunomodulation.

Koller LD, Exon JH, Moore SA, Watanabe PG.

J Toxicol Environ Health. 1983 Jan;11(1):15-22.

PMID:
6402602
22.

[14C]Methyl chloroform (1,1,1-trichloroethane): pharmacokinetics in rats and mice following inhalation exposure.

Schumann AM, Fox TR, Watanabe PG.

Toxicol Appl Pharmacol. 1982 Mar 15;62(3):390-401. No abstract available.

PMID:
7071857
23.

Pharmacokinetics and macromolecular interactions of ethylene dichloride in rats after inhalation or gavage.

Reitz RH, Fox TR, Ramsey JC, Quast JF, Langvardt PW, Watanabe PG.

Toxicol Appl Pharmacol. 1982 Feb;62(2):190-204. No abstract available.

PMID:
7058523
24.

A comparison of the fate of inhaled methyl chloroform (1,1,1-trichloroethane) following single or repeated exposure in rats and mice.

Schumann AM, Fox TR, Watanabe PG.

Fundam Appl Toxicol. 1982 Jan-Feb;2(1):27-32. No abstract available.

PMID:
7185599
25.

Genetic vs. nongenetic chemical carcinogenesis and risk assessment.

Reitz RH, Schumann AM, Watanabe PG, Gehring PJ.

Basic Life Sci. 1982;21:425-38. No abstract available.

PMID:
7150203
26.

The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats.

Stott WT, Quast JF, Watanabe PG.

Toxicol Appl Pharmacol. 1982 Jan;62(1):137-51. No abstract available.

PMID:
7064149
27.

Differentiation of genetic versus epigenetic mechanisms of toxicity and its application to risk assessment.

Stott WT, Watanabe PG.

Drug Metab Rev. 1982;13(5):853-73. Review. No abstract available.

PMID:
6754312
28.
29.

Genetic and nongenetic events in neoplasia.

Stott WT, Reitz RH, Schumann AM, Watanabe PG.

Food Cosmet Toxicol. 1981 Oct;19(5):567-76. Review. No abstract available.

PMID:
7030886
30.

Differentiation of the mechanisms of oncogenicity of 1,4-dioxane and 1,3-hexachlorobutadiene in the rat.

Stott WT, Quast JF, Watanabe PG.

Toxicol Appl Pharmacol. 1981 Sep 15;60(2):287-300. No abstract available.

PMID:
7281189
31.

Translation of pharmacokinetic/biochemical data into risk assessment.

Dietz FK, Reitz RH, Watanabe PG, Gehring PJ.

Adv Exp Med Biol. 1981;136 Pt B:1399-424. No abstract available.

PMID:
7344516
32.

Kinetic interaction of chemical mutagens with mouse sperm in vivo as it relates to animal mutagenic effects.

Stott WT, Watanabe PG.

Toxicol Appl Pharmacol. 1980 Sep 30;55(3):411-6. No abstract available.

PMID:
7434354
33.

The pharmacokinetics and macromolecular interactions of perchloroethylene in mice and rats as related to oncogenicity.

Schumann AM, Quast JF, Watanabe PG.

Toxicol Appl Pharmacol. 1980 Sep 15;55(2):207-19. No abstract available.

PMID:
7423514
34.

In vitro activation of 1,2-dichloroethane by microsomal and cytosolic enzymes.

Guengerich FP, Crawford WM Jr, Domoradzki JY, Macdonald TL, Watanabe PG.

Toxicol Appl Pharmacol. 1980 Sep 15;55(2):303-17. No abstract available.

PMID:
6999663
35.

Effects of vinylidene chloride on DNA synthesis and DNA repair in the rat and mouse: a comparative study with dimethylnitrosamine.

Reitz RH, Watanabe PG, McKenna MJ, Quast JF, Gehring PJ.

Toxicol Appl Pharmacol. 1980 Mar 15;52(3):357-70. No abstract available.

PMID:
7368211
36.

Non-linear pharmacokinetic parameters need to be considered in high dose/low dose extrapolation.

Reitz RH, Quast JF, Schumann AM, Watanabe PG, Gehring PJ.

Arch Toxicol Suppl. 1980;3:79-94.

PMID:
6930952
37.

Disposition of tetrachloro(14C)ethylene following oral and inhalation exposure in rats.

Pegg DG, Zempel JA, Braun WH, Watanabe PG.

Toxicol Appl Pharmacol. 1979 Dec;51(3):465-74. No abstract available.

PMID:
538758
38.

Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde.

Guengerich FP, Crawford WM Jr, Watanabe PG.

Biochemistry. 1979 Nov 13;18(23):5177-82. No abstract available.

PMID:
497175
39.

Chemical carcinogens: estimating the risk.

Reitz RH, Quast JF, Watanabe PG, Gehring PJ.

Science. 1979 Sep 21;205(4412):1206-8. No abstract available.

PMID:
472737
40.

Risk of angiosarcoma in workers exposed to vinyl chloride as predicted from studies in rats.

Gehring PJ, Watanabe PG, Park CN.

Toxicol Appl Pharmacol. 1979 Jun 15;49(1):15-21. No abstract available.

PMID:
573001
41.

Metabolism of [14C]- and [36C]-labeled vinyl chloride in vivo and in vitro.

Guengerich FP, Watanabe PG.

Biochem Pharmacol. 1979 Mar 1;28(5):589-96. No abstract available.

PMID:
444246
42.

Effect of methylene chloride on the oxyhemoglobin dissociation curve of rat and human blood.

Dill DC, Watanabe PG, Norris JM.

Toxicol Appl Pharmacol. 1978 Oct;46(1):125-9. No abstract available.

PMID:
725938
43.

Hepatic macromolecular binding following exposure to vinyl chloride.

Watanabe PG, Zempel JA, Pegg DG, Gehring PJ.

Toxicol Appl Pharmacol. 1978 Jun;44(3):571-9. No abstract available.

PMID:
684749
44.

Resolution of dose-response toxicity data for chemicals requiring metabolic activation: example--vinyl chloride.

Gehring PJ, Watanabe PG, Park CN.

Toxicol Appl Pharmacol. 1978 Jun;44(3):581-91. No abstract available.

PMID:
567390
45.

Comparison of the fate of vinyl chloride following single and repeated exposure in rats.

Watanabe PG, Zempel JA, Gehring PJ.

Toxicol Appl Pharmacol. 1978 May;44(2):391-9. No abstract available.

PMID:
675709
46.

Pharmacokinetics of vinylidene chloride in the rat.

McKenna MJ, Watanabe PG, Gehring PJ.

Environ Health Perspect. 1977 Dec;21:99-105.

47.

The importance of non-linear (dose-dependent) pharmacokinetics in hazard assessment.

Watanabe PG, Young JD, Gehring PJ.

J Environ Pathol Toxicol. 1977 Nov-Dec;1(2):147-59.

PMID:
553128
48.

Tri-O-tolyl phosphate neurotoxicity: lack of evidence for autoimmunologic involvement.

Watanabe PG, Sharma RP.

Arch Environ Contam Toxicol. 1977;6(2-3):233-40.

PMID:
901003
49.

Dose-dependent fate of vinyl chloride and its possible relationship to oncogenicity in rats.

Watanabe PG, Gehring PJ.

Environ Health Perspect. 1976 Oct;17:145-52.

50.

Fate of [14C]vinyl chloride following inhalation exposure in rats.

Watanabe PG, McGowan GR, Madrid EO, Gehring PJ.

Toxicol Appl Pharmacol. 1976 Jul;37(1):49-59. No abstract available.

PMID:
968906

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