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Comprehensive Exploration to Identify Predictive DNA Markers of ΔNp63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma.

Ooizumi Y, Kojima K, Igarashi K, Tanaka Y, Harada H, Yokota K, Kaida T, Ishii S, Tanaka T, Yokoi K, Nishizawa N, Washio M, Ushiku H, Katoh H, Kosaka Y, Mieno H, Hosoda K, Watanabe M, Katada C, Hiki N, Yamashita K.

Ann Surg Oncol. 2019 Sep 16. doi: 10.1245/s10434-019-07795-w. [Epub ahead of print]


Simultaneous Development of Progressive Multifocal Leukoencephalopathy and Cryptococcal Meningitis during Methotrexate and Infliximab Treatment.

Nosaki Y, Ohyama K, Watanabe M, Yokoi T, Nakamichi K, Saijo M, Miura Y, Iwai K.

Intern Med. 2019;58(18):2703-2709. doi: 10.2169/internalmedicine.2570-18. Epub 2019 Sep 15.


Microflora of Mycotoxigenic Fungi in Rice Grains in Kyushu Region of Japan and Their Changes during Storage under non-Controlled Conditions.

Kobayashi N, Sakurai K, Nakarai R, Shigaki K, Horikawa K, Honda M, Sugiura Y, Watanabe M, Takino M, Sugita-Konishi Y.

Biocontrol Sci. 2019;24(3):161-166. doi: 10.4265/bio.24.161.


β-Adrenergic Blocker, Carvedilol, Abolishes Ameliorating Actions of Adipose-Derived Stem Cell Sheets on Cardiac Dysfunction and Remodeling After Myocardial Infarction.

Adachi M, Watanabe M, Kurata Y, Inoue Y, Notsu T, Yamamoto K, Horie H, Tanno S, Morita M, Miake J, Hamada T, Kuwabara M, Nakasone N, Ninomiya H, Tsuneto M, Shirayoshi Y, Yoshida A, Nishimura M, Yamamoto K, Hisatome I.

Circ J. 2019 Sep 13. doi: 10.1253/circj.CJ-19-0261. [Epub ahead of print]


Plasma Levels of Soluble PD-L1 Correlate With Tumor Regression in Patients With Lung and Gastric Cancer Treated With Immune Checkpoint Inhibitors.

Ando K, Hamada K, Watanabe M, Ohkuma R, Shida M, Onoue R, Kubota Y, Matsui H, Ishiguro T, Hirasawa Y, Ariizumi H, Tsurutani J, Yoshimura K, Tsunoda T, Kobayashi S, Wada S.

Anticancer Res. 2019 Sep;39(9):5195-5201. doi: 10.21873/anticanres.13716.


Long-term use of interferon-β in multiple sclerosis increases Vδ1-Vδ2-Vγ9- γδ T cells that are associated with a better outcome.

Maimaitijiang G, Watanabe M, Shinoda K, Isobe N, Nakamura Y, Masaki K, Matsushita T, Yoshikai Y, Kira JI.

J Neuroinflammation. 2019 Sep 13;16(1):179. doi: 10.1186/s12974-019-1574-5.


The canine RAD51 mutation leads to the attenuation of interaction with PALB2.

Uemura M, Ochiai K, Morimatsu M, Michishita M, Onozawa E, Azakami D, Uno Y, Yoshikawa Y, Sasaki T, Watanabe M, Omi T.

Vet Comp Oncol. 2019 Sep 13. doi: 10.1111/vco.12542. [Epub ahead of print]


Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide.

Nobashi T, Saga T, Nakamoto Y, Shimizu Y, Koyasu S, Ishimori T, Watanabe M, Kimura H, Togashi K.

Endocr Regul. 2018 Oct 1;52(4):185-191. doi: 10.2478/enr-2018-0023.


Pseudomonas aeruginosa-derived flagellin stimulates IL-6 and IL-8 production in human bronchial epithelial cells: A potential mechanism for progression and exacerbation of COPD.

Nakamoto K, Watanabe M, Sada M, Inui T, Nakamura M, Honda K, Wada H, Ishii H, Takizawa H.

Exp Lung Res. 2019 Sep 13:1-12. doi: 10.1080/01902148.2019.1665147. [Epub ahead of print]


Analyses of natural courses of Japanese patients with Alzheimer's disease using placebo data from placebo-controlled, randomized clinical trials: Japanese Study on the Estimation of Clinical course of Alzheimer's disease.

Watanabe M, Nakamura Y, Yoshiyama Y, Kagimura T, Kawaguchi H, Matsuzawa H, Tachibana Y, Nishimura K, Kubota N, Kobayashi M, Saito T, Tamura K, Sato T, Takahashi M; Japanese Society of Scaling Keys of Evaluation Techniques for CNS Disorders Heterogeneity (SKETCH) study group, Homma A.

Alzheimers Dement (N Y). 2019 Aug 29;5:398-408. doi: 10.1016/j.trci.2019.07.004. eCollection 2019.


Pneumorrhachis in children: A report of two cases and review of the literature.

Yaginuma K, Watanabe M, Saito Y, Takahashi N, Ohara Y, Kobayashi S, Mochizuki K, Suyama K, Sato M, Sano H, Hashimoto K, Kikuta A, Hosoya M.

Radiol Case Rep. 2019 Sep 5;14(11):1325-1329. doi: 10.1016/j.radcr.2019.08.010. eCollection 2019 Nov.


Successful management of severe asthma in a young boy with eosinophilic chronic rhinosinusitis who received omalizumab: a case report.

Shoda Y, Watanabe M, Wada K, Soutome T, Komine Y, Mikami T, Nemoto T, Ohara A.

Allergy Asthma Clin Immunol. 2019 Sep 5;15:55. doi: 10.1186/s13223-019-0369-7. eCollection 2019.


Surface Pre-Reacted Glass Filler Contributes to Tertiary Dentin Formation through a Mechanism Different Than That of Hydraulic Calcium-Silicate Cement.

Okamoto M, Ali M, Komichi S, Watanabe M, Huang H, Ito Y, Miura J, Hirose Y, Mizuhira M, Takahashi Y, Okuzaki D, Kawabata S, Imazato S, Hayashi M.

J Clin Med. 2019 Sep 11;8(9). pii: E1440. doi: 10.3390/jcm8091440.


X-ray pumping of the 229Th nuclear clock isomer.

Masuda T, Yoshimi A, Fujieda A, Fujimoto H, Haba H, Hara H, Hiraki T, Kaino H, Kasamatsu Y, Kitao S, Konashi K, Miyamoto Y, Okai K, Okubo S, Sasao N, Seto M, Schumm T, Shigekawa Y, Suzuki K, Stellmer S, Tamasaku K, Uetake S, Watanabe M, Watanabe T, Yasuda Y, Yamaguchi A, Yoda Y, Yokokita T, Yoshimura M, Yoshimura K.

Nature. 2019 Sep;573(7773):238-242. doi: 10.1038/s41586-019-1542-3. Epub 2019 Sep 11.


Endovascular Revascularization Improves the Central Hemodynamics and Augmentation Index in Patients with Peripheral Artery Disease.

Watanabe K, Takahashi H, Watanabe T, Otaki Y, Kato S, Tamura H, Nishiyama S, Arimoto T, Shishido T, Watanabe M.

Intern Med. 2019 Sep 11. doi: 10.2169/internalmedicine.3413-19. [Epub ahead of print]


Discovery and characterization of a small-molecule enteropeptidase inhibitor, SCO-792.

Sasaki M, Miyahisa I, Itono S, Yashiro H, Hiyoshi H, Tsuchimori K, Hamagami KI, Moritoh Y, Watanabe M, Tohyama K, Sasaki M, Sakamoto JI, Kawamoto T.

Pharmacol Res Perspect. 2019 Sep 4;7(5):e00517. doi: 10.1002/prp2.517. eCollection 2019 Oct.


Association of CD58 Polymorphisms and its Protein Expression with the Development and Prognosis of Autoimmune Thyroid Diseases.

Yamamoto M, Watanabe M, Inoue N, Watanabe A, Ozaki H, Ohsaki M, Hidaka Y, Iwatani Y.

Immunol Invest. 2019 Sep 11:1-14. doi: 10.1080/08820139.2019.1659811. [Epub ahead of print]


Assessment of abdominal organ motion using cine magnetic resonance imaging in different gastric motilities: a comparison between fasting and postprandial states.

Nonaka H, Onishi H, Watanabe M, Nam VH.

J Radiat Res. 2019 Aug 24. pii: rrz054. doi: 10.1093/jrr/rrz054. [Epub ahead of print]


Overexpression of p53 due to excess protein O-GlcNAcylation is associated with coronary microvascular disease in type 2 diabetes.

Si R, Zhang Q, Tsuji-Hosokawa A, Watanabe M, Willson C, Lai N, Wang J, Dai A, Scott BT, Dillmann WH, Yuan JX, Makino A.

Cardiovasc Res. 2019 Aug 22. pii: cvz216. doi: 10.1093/cvr/cvz216. [Epub ahead of print]


Chloroquine differentially modulates coronary vasodilation in control and diabetic mice.

Zhang Q, Tsuji-Hosokawa A, Willson C, Watanabe M, Si R, Lai N, Wang Z, Yuan JX, Wang J, Makino A.

Br J Pharmacol. 2019 Sep 10. doi: 10.1111/bph.14864. [Epub ahead of print]


Ulcerative colitis outcomes research in Japan: protocol for an observational prospective cohort study of YOURS (YOu and Ulcerative colitis: Registry and Social network).

Yamazaki H, Matsuoka K, Fernandez J, Hibi T, Watanabe M, Hisamatsu T, Fukuhara S.

BMJ Open. 2019 Sep 8;9(9):e030134. doi: 10.1136/bmjopen-2019-030134.


Analysis of the mechanism underlying liver diseases using human induced pluripotent stem cells.

Kakinuma S, Watanabe M.

Immunol Med. 2019 Sep 9:1-8. doi: 10.1080/25785826.2019.1657254. [Epub ahead of print]


The association between bilateral maximum occlusal force and all-cause mortality among community-dwelling older adults: The Tsurugaya project.

Ohi T, Komiyama T, Miyoshi Y, Murakami T, Tsuboi A, Tomata Y, Tsuji I, Watanabe M, Hattori Y.

J Prosthodont Res. 2019 Sep 4. pii: S1883-1958(19)30055-6. doi: 10.1016/j.jpor.2019.08.005. [Epub ahead of print]


5-Fluorouracil exacerbates cefepime-induced convulsions in pentylenetetrazol-kindled mice.

Suemaru K, Yoshikawa M, Aso H, Watanabe M.

Epilepsy Res. 2019 Aug 29;157:106195. doi: 10.1016/j.eplepsyres.2019.106195. [Epub ahead of print]


The analysis of percutaneous pedicle screw technique with guide wire-less in lateral decubitus position following extreme lateral interbody fusion.

Hiyama A, Sakai D, Sato M, Watanabe M.

J Orthop Surg Res. 2019 Sep 5;14(1):304. doi: 10.1186/s13018-019-1354-z.


Contribution of systemic inflammation and nutritional status to the relationship between tooth loss and mortality in a community-dwelling older Japanese population: a mediation analysis of data from the Tsurugaya project.

Hiratsuka T, Komiyama T, Ohi T, Tanji F, Tomata Y, Tsuji I, Watanabe M, Hattori Y.

Clin Oral Investig. 2019 Sep 4. doi: 10.1007/s00784-019-03072-y. [Epub ahead of print]


Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening.

Yamada S, Kawasaki M, Fujihara M, Watanabe M, Takamura Y, Takioku M, Nishioka H, Takeuchi Y, Makishima M, Motoyama T, Ito S, Tokiwa H, Nakano S, Kakuta H.

J Med Chem. 2019 Sep 18. doi: 10.1021/acs.jmedchem.9b00995. [Epub ahead of print]


Recent progress in haploidentical transplantation: is this the optimal choice for alternative donor transplantation?

Watanabe M, Kanda J.

Curr Opin Hematol. 2019 Sep 2. doi: 10.1097/MOH.0000000000000532. [Epub ahead of print]


Pre-conception status, obstetric outcome and use of medications during pregnancy of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) in Japan: multi-center retrospective descriptive study.

Tsuda S, Sameshima A, Sekine M, Kawaguchi H, Fujita D, Makino S, Morinobu A, Murakawa Y, Matsui K, Sugiyama T, Watanabe M, Suzuki Y, Nagahori M, Murashima A, Atsumi T, Oku K, Mitsuda N, Takei S, Miyamae T, Takahashi N, Nakajima K, Saito S; Ministry of Health Labour and Welfare Working Group for“Guideline for The Treatment of Rheumatoid Arthritis or Inflammatory Bowel Disease Bearing Women in Child-bearing Age.”.

Mod Rheumatol. 2019 Sep 4:1-26. doi: 10.1080/14397595.2019.1661592. [Epub ahead of print]


Phase I trial of pimasertib monotherapy in Japanese patients with solid tumors and those with hepatocellular carcinoma.

Yamazaki K, Doi T, Ikeda M, Okusaka T, Schueler A, Watanabe M, Ohtsu A.

Cancer Chemother Pharmacol. 2019 Sep 3. doi: 10.1007/s00280-019-03924-0. [Epub ahead of print]


Combined effect of weight gain within normal weight range and parental hypertension on the prevalence of hypertension; from the J-MICC Study.

Okada R, Kadomatsu Y, Tsukamoto M, Sasakabe T, Kawai S, Tamura T, Hishida A, Ikezaki H, Furusyo N, Tanaka K, Hara M, Suzuki S, Watanabe M, Takezaki T, Nishimoto D, Matsui D, Watanabe I, Kuriki K, Takashima N, Nakamura Y, Katsuura-Kamano S, Arisawa K, Mikami H, Nakamura Y, Oze I, Koyanagi YN, Naito M, Wakai K; Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

J Hum Hypertens. 2019 Sep 3. doi: 10.1038/s41371-019-0230-y. [Epub ahead of print]


The association between genotypes of urate transporter-1, Serum uric acid, and mortality in the community-based population: the Yamagata (Takahata) Study.

Kon S, Konta T, Ichikawa K, Watanabe M, Sato H, Ishizawa K, Ueno Y, Yamashita H, Kayama T.

Clin Exp Nephrol. 2019 Sep 3. doi: 10.1007/s10157-019-01781-y. [Epub ahead of print]


Pilot study for risk assessment of aspiration pneumonia based on oral bacteria levels and serum biomarkers.

Nishizawa T, Niikura Y, Akasaka K, Watanabe M, Kurai D, Amano M, Ishii H, Matsushima H, Yamashita N, Takizawa H.

BMC Infect Dis. 2019 Sep 2;19(1):761. doi: 10.1186/s12879-019-4327-2.


GDF-15, a mitochondrial disease biomarker, is associated with the severity of multiple sclerosis.

Nohara S, Ishii A, Yamamoto F, Yanagiha K, Moriyama T, Tozaka N, Miyake Z, Yatsuga S, Koga Y, Hosaka T, Terada M, Yamaguchi T, Aizawa S, Mamada N, Tsuji H, Tomidokoro Y, Nakamagoe K, Ishii K, Watanabe M, Tamaoka A.

J Neurol Sci. 2019 Aug 22;405:116429. doi: 10.1016/j.jns.2019.116429. [Epub ahead of print]


Genetic and tissue-specific RNA-sequencing analysis of self-compatible mutant TSC28 in Brassica rapa L. toward identification of a novel self-incompatibility factor.

Osaka M, Nabemoto M, Maeda S, Sakazono S, Masuko-Suzuki H, Ito K, Takada Y, Kobayashi I, Lim YP, Nakazono M, Fujii S, Murase K, Takayama S, Suzuki G, Suwabe K, Watanabe M.

Genes Genet Syst. 2019 Aug 31. doi: 10.1266/ggs.19-00010. [Epub ahead of print]


Three cases of free flap anastomoses to the descending genicular artery for knee joint trauma with severe soft tissue injury.

Kobayashi Y, Uchiyama Y, Ishii T, Nakajima D, Yanagisawa S, Saito I, Watanabe M.

J Orthop Sci. 2019 Aug 29. pii: S0949-2658(19)30253-2. doi: 10.1016/j.jos.2019.08.002. [Epub ahead of print] No abstract available.


CD33+ Immature Myeloid Cells Critically Predict Recurrence in Advanced Gastric Cancer.

Soeno T, Katoh H, Ishii S, Ushiku H, Hosoda K, Hiki N, Watanabe M, Yamashita K.

J Surg Res. 2019 Aug 28;245:552-563. doi: 10.1016/j.jss.2019.07.095. [Epub ahead of print]


Inflammatory response and recurrence after minimally invasive esophagectomy.

Okamura A, Yamashita K, Kozuki R, Takahashi K, Toihata T, Imamura Y, Mine S, Watanabe M.

Langenbecks Arch Surg. 2019 Aug 30. doi: 10.1007/s00423-019-01818-6. [Epub ahead of print]


Serum GFAP and neurofilament light as biomarkers of disease activity and disability in NMOSD.

Watanabe M, Nakamura Y, Michalak Z, Isobe N, Barro C, Leppert D, Matsushita T, Hayashi F, Yamasaki R, Kuhle J, Kira JI.

Neurology. 2019 Aug 30. pii: 10.1212/WNL.0000000000008160. doi: 10.1212/WNL.0000000000008160. [Epub ahead of print]


Clinical significance of urinary L-FABP in the emergency department.

Suzuki G, Ichibayashi R, Yamamoto S, Nakamichi Y, Watanabe M, Honda M.

Int J Emerg Med. 2019 Aug 30;12(1):24. doi: 10.1186/s12245-019-0244-9.


Protein S100-A7 Derived from Digested Dentin Is a Critical Molecule for Dentin Pulp Regeneration.

Komichi S, Takahashi Y, Okamoto M, Ali M, Watanabe M, Huang H, Nakai T, Cooper P, Hayashi M.

Cells. 2019 Aug 29;8(9). pii: E1002. doi: 10.3390/cells8091002.


Annulus fibrosus cell sheets limit disc degeneration in a rat annulus fibrosus injury model.

Nukaga T, Sakai D, Schol J, Sato M, Watanabe M.

JOR Spine. 2019 Jun 17;2(2):e1050. doi: 10.1002/jsp2.1050. eCollection 2019 Jun.


Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan.

Fujii Y, Takeda Y, Kurihara I, Itoh H, Katabami T, Ichijo T, Wada N, Shibayama Y, Yoshimoto T, Ogawa Y, Kawashima J, Sone M, Inagaki N, Takahashi K, Watanabe M, Matsuda Y, Kobayashi H, Shibata H, Kamemura K, Otsuki M, Yamamto K, Ogo A, Yanase T, Okamura S, Miyauchi S, Fujita M, Suzuki T, Umakoshi H, Ogasawara T, Tsuiki M, Naruse M; JPAS Study Group.

J Hum Hypertens. 2019 Aug 28. doi: 10.1038/s41371-019-0229-4. [Epub ahead of print]


Peripartum Management of Pregnant Women With Congenital Heart Disease.

Yamasaki K, Sawatari H, Konagai N, Kamiya CA, Yoshimatsu J, Muneuchi J, Watanabe M, Fukuda T, Mizuno A, Sakamoto I, Yamamura K, Ohkusa T, Tsutsui H, Niwa K, Chishaki A.

Circ J. 2019 Aug 29. doi: 10.1253/circj.CJ-19-0369. [Epub ahead of print]


Endoscopic Balloon Dilation for Benign Bilioenteric Stricture: Outcomes and Factors Affecting Recurrence.

Yamauchi H, Kida M, Miyata E, Okuwaki K, Iwai T, Minato N, Tadehara M, Watanabe M, Imaizumi H, Koizumi W.

Dig Dis Sci. 2019 Aug 28. doi: 10.1007/s10620-019-05811-3. [Epub ahead of print]


Acute aortic regurgitation after post-dilatation: first case of crashed leaflet in transcatheter aortic valve implantation.

Okuyama K, Watanabe M, Kamijima R, Izumo M, Tanabe Y, Akashi YJ.

Cardiovasc Interv Ther. 2019 Aug 23. doi: 10.1007/s12928-019-00614-9. [Epub ahead of print] No abstract available.


Virtual histology intravascular ultrasound evaluation of coronary artery lesions within 1 year and more than 10 years after the onset of Kawasaki disease.

Watanabe M, Fukazawa R, Ogawa S, Ohkubo T, Abe M, Hashimoto K, Hashimoto Y, Itoh Y.

J Cardiol. 2019 Aug 21. pii: S0914-5087(19)30236-9. doi: 10.1016/j.jjcc.2019.06.015. [Epub ahead of print]


Small Bowel Healing Detected by Endoscopy in Patients With Crohn's Disease After Treatment With Antibodies Against Tumor Necrosis Factor.

Takenaka K, Fujii T, Suzuki K, Shimizu H, Motobayashi M, Hibiya S, Saito E, Nagahori M, Watanabe M, Ohtsuka K.

Clin Gastroenterol Hepatol. 2019 Aug 20. pii: S1542-3565(19)30899-7. doi: 10.1016/j.cgh.2019.08.024. [Epub ahead of print]


A Patient with Type 3 Autoimmune Polyglandular Syndrome who Developed Systemic Lupus Erythematosus 8 years after the Diagnosis of Autoimmune Hepatitis.

Mifune-Morioka T, Uchida HA, Fukushima K, Watanabe M, Ouchi C, Mise K, Kawakita C, Kano Y, Onishi A, Toma K, Eguchi J, Wada N, Ikeda F, Sasaki E, Suganami Y, Kishida M, Sugiyama H, Okada H, Wada J.

Acta Med Okayama. 2019 Aug;73(4):367-372. doi: 10.18926/AMO/56940.


Thumb Carpometacarpal Arthroplasty with Dynamic Suspension Sling Using Extensor Carpi Radialis Tendon.

Takagi T, Kobayashi Y, Watanabe M.

J Hand Surg Asian Pac Vol. 2019 Sep;24(3):353-358. doi: 10.1142/S2424835519500450.


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