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Items: 36

1.

Pentoxifylline blocks hepatic stellate cell activation independently of phosphodiesterase inhibitory activity.

Lee KS, Cottam HB, Houglum K, Wasson DB, Carson D, Chojkier M.

Am J Physiol. 1997 Nov;273(5):G1094-100. doi: 10.1152/ajpgi.1997.273.5.G1094.

PMID:
9374707
3.

New adenosine kinase inhibitors with oral antiinflammatory activity: synthesis and biological evaluation.

Cottam HB, Wasson DB, Shih HC, Raychaudhuri A, Di Pasquale G, Carson DA.

J Med Chem. 1993 Oct 29;36(22):3424-30.

PMID:
8230132
4.

Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.

Carson DA, Wasson DB, Esparza LM, Carrera CJ, Kipps TJ, Cottam HB.

Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2970-4.

5.

Dependence of cell survival on DNA repair in human mononuclear phagocytes.

Terai C, Wasson DB, Carrera CJ, Carson DA.

J Immunol. 1991 Dec 15;147(12):4302-6.

PMID:
1753100
6.

Deoxyadenosine-resistant human T lymphoblasts with elevated 5'-nucleotidase activity.

Carson DA, Carrera CJ, Wasson DB, Iizasa T.

Biochim Biophys Acta. 1991 Jan 10;1091(1):22-8.

PMID:
1995064
7.

2-halo-2',3'-dideoxyadenosines: metabolically stable dideoxynucleosides with activity against the human immunodeficiency virus (HIV).

Carson DA, Haertle T, Carrera CJ, Willis EH, Wasson DB, Richman DD.

Adv Exp Med Biol. 1989;253B:395-8. No abstract available.

PMID:
2610127
8.

Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia.

Carson DA, Piro LD, Wasson DB, Carrera CJ, Beutler E.

Adv Exp Med Biol. 1989;253A:427-31. Review. No abstract available.

PMID:
2576181
9.

Characterization of poly(ADP-ribose) polymerase with human autoantibodies.

Yamanaka H, Penning CA, Willis EH, Wasson DB, Carson DA.

Adv Exp Med Biol. 1989;253B:259-65. No abstract available.

PMID:
2514589
10.

Utilization of 2'-deoxynad for ADP-ribose transfer reactions.

Wasson DB, Yamanaka H, Carson DA.

Adv Exp Med Biol. 1989;253B:213-8.

PMID:
2514587
11.

Heterogeneity of the toxic mechanisms of methylthioadenosine in methylthioadenosine phosphorylase deficient murine lymphoma cells.

Yamanaka H, Kajander, Olavi E, Kubota M, Wasson DB, Willis EH, Carson DA.

Adv Exp Med Biol. 1989;253B:193-9. No abstract available.

PMID:
2514586
12.

Synthesis of 2',3'-dideoxynucleosides by enzymatic trans-glycosylation.

Carson DA, Wasson DB.

Biochem Biophys Res Commun. 1988 Sep 15;155(2):829-34.

PMID:
3262341
13.

Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives.

Haertle T, Carrera CJ, Wasson DB, Sowers LC, Richman DD, Carson DA.

J Biol Chem. 1988 Apr 25;263(12):5870-5.

14.

Biochemical genetic analysis of 2',3'-dideoxyadenosine metabolism in human T lymphocytes.

Carson DA, Haertle T, Wasson DB, Richman DD.

Biochem Biophys Res Commun. 1988 Mar 15;151(2):788-93.

PMID:
3258154
15.

Characterization of human poly(ADP-ribose) polymerase with autoantibodies.

Yamanaka H, Penning CA, Willis EH, Wasson DB, Carson DA.

J Biol Chem. 1988 Mar 15;263(8):3879-83.

16.

Programmed cell death and adenine deoxynucleotide metabolism in human lymphocytes.

Carson DA, Carrera CJ, Wasson DB, Yamanaka H.

Adv Enzyme Regul. 1988;27:395-404.

PMID:
2907967
17.

Pyridine nucleotide cycling and poly(ADP-ribose) synthesis in resting human lymphocytes.

Carson DA, Seto S, Wasson DB.

J Immunol. 1987 Mar 15;138(6):1904-7.

PMID:
2950173
18.

DNA strand breaks, NAD metabolism, and programmed cell death.

Carson DA, Seto S, Wasson DB, Carrera CJ.

Exp Cell Res. 1986 Jun;164(2):273-81.

PMID:
2940104
19.

Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes.

Seto S, Carrera CJ, Wasson DB, Carson DA.

J Immunol. 1986 Apr 15;136(8):2839-43.

PMID:
2870121
20.
21.

Genetic analysis of deoxyadenosine toxicity in dividing human lymphoblasts.

Carson DA, Carrera CJ, Kubota M, Wasson DB, Iizasa T.

Adv Exp Med Biol. 1986;195 Pt B:207-11. No abstract available.

PMID:
3020905
22.

Biochemical basis for deoxyadenosine and 2-chlorodeoxyadenosine toxicity to resting human lymphocytes.

Seto S, Carrera CJ, Wasson DB, Carson DA.

Adv Exp Med Biol. 1986;195 Pt B:577-82. No abstract available.

PMID:
2876594
23.

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.

Seto S, Carrera CJ, Kubota M, Wasson DB, Carson DA.

J Clin Invest. 1985 Feb;75(2):377-83.

24.

Metabolic basis for immune dysfunction in adenosine deaminase deficiency.

Carson DA, Iizasa T, Seto S, Carrera CJ, Kubota M, Willis EH, Wasson DB, Kajander O.

Ann N Y Acad Sci. 1985;451:34-41. No abstract available.

PMID:
3878120
25.

Deoxynucleoside overproduction in deoxyadenosine-resistant, adenosine deaminase-deficient human histiocytic lymphoma cells.

Kubota M, Carrera CJ, Wasson DB, Carson DA.

Biochim Biophys Acta. 1984 May 22;804(1):37-43.

PMID:
6372866
26.

Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine.

Carson DA, Wasson DB, Beutler E.

Proc Natl Acad Sci U S A. 1984 Apr;81(7):2232-6.

27.

Biochemical basis for lymphocyte dysfunction in adenosine deaminase and purine nucleoside phosphorylase deficiencies.

Carson DA, Wasson DB, Lakow E, Kamatani N.

Adv Exp Med Biol. 1984;165 Pt B:133-9. No abstract available.

PMID:
6426261
28.

Cell cycle independent lymphocytotoxicity of 2-chlorodeoxyadenosine.

Carson DA, Wasson DB, Yu A.

Adv Exp Med Biol. 1984;165 Pt B:351-6. No abstract available.

PMID:
6144251
29.
31.

Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells.

Hershfield MS, Fetter JE, Small WC, Bagnara AS, Williams SR, Ullman B, Martin DW Jr, Wasson DB, Carson DA.

J Biol Chem. 1982 Jun 10;257(11):6380-6. No abstract available.

33.

Lymphocyte dysfunction caused by deficiencies in purine metabolism.

Carson DA, Lakow E, Wasson DB, Kamatani N.

Immunol Today. 1981 Dec;2(12):234-8. doi: 10.1016/0167-5699(81)90010-4.

PMID:
25290650
34.
35.

Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo.

Carson DA, Wasson DB, Kaye J, Ullman B, Martin DW Jr, Robins RK, Montgomery JA.

Proc Natl Acad Sci U S A. 1980 Nov;77(11):6865-9.

36.

Differences in deoxyadenosine metabolism in human and mouse lymphocytes.

Carson DA, Kaye J, Wasson DB.

J Immunol. 1980 Jan;124(1):8-12. No abstract available.

PMID:
6965300

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