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Items: 38


Surfactant expression defines an inflamed subtype of lung adenocarcinoma brain metastases that correlates with prolonged survival.

Pocha K, Mock A, Rapp C, Dettling S, Warta R, Geisenberger C, Jungk C, Martins LR, Grabe N, Reuss D, Debus J, von Deimling A, Abdollahi A, Unterberg A, Herold-Mende CC.

Clin Cancer Res. 2020 Jan 17. pii: clincanres.2184.2019. doi: 10.1158/1078-0432.CCR-19-2184. [Epub ahead of print]


Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT.

Jungwirth G, Warta R, Beynon C, Sahm F, von Deimling A, Unterberg A, Herold-Mende C, Jungk C.

Acta Neuropathol Commun. 2019 Aug 30;7(1):140. doi: 10.1186/s40478-019-0793-4.


Extent of Resection, MGMT Promoter Methylation Status and Tumor Location Independently Predict Progression-Free Survival in Adult Sporadic Pilocytic Astrocytoma.

Jungk C, Reinhardt A, Warta R, Capper D, Deimling AV, Herold-Mende C, Unterberg A.

Cancers (Basel). 2019 Jul 29;11(8). pii: E1072. doi: 10.3390/cancers11081072.


Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas.

Rapp C, Dettling S, Liu F, Ull AT, Warta R, Jungk C, Roesch S, Mock A, Sahm F, Schmidt M, Jungwirth G, Zweckberger K, Lamszus K, Gousias K, Kessler AF, Grabe N, Loehr M, Ketter R, Urbschat S, Senft C, Westphal M, Abdollahi A, Debus J, von Deimling A, Unterberg A, Simon M, Herold-Mende CC.

Clin Cancer Res. 2019 Sep 1;25(17):5260-5270. doi: 10.1158/1078-0432.CCR-19-0389. Epub 2019 Jun 21.


Impact of post-surgical freezing delay on brain tumor metabolomics.

Mock A, Rapp C, Warta R, Abdollahi A, Jäger D, Sakowitz O, Brors B, von Deimling A, Jungk C, Unterberg A, Herold-Mende C.

Metabolomics. 2019 May 13;15(5):78. doi: 10.1007/s11306-019-1541-2.


Identification of KIF11 As a Novel Target in Meningioma.

Jungwirth G, Yu T, Moustafa M, Rapp C, Warta R, Jungk C, Sahm F, Dettling S, Zweckberger K, Lamszus K, Senft C, Loehr M, Keßler AF, Ketter R, Westphal M, Debus J, von Deimling A, Simon M, Unterberg A, Abdollahi A, Herold-Mende C.

Cancers (Basel). 2019 Apr 15;11(4). pii: E545. doi: 10.3390/cancers11040545.


Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche.

Chiblak S, Tang Z, Lemke D, Knoll M, Dokic I, Warta R, Moustafa M, Mier W, Brons S, Rapp C, Muschal S, Seidel P, Bendszus M, Adeberg S, Wiestler OD, Haberkorn U, Debus J, Herold-Mende C, Wick W, Abdollahi A.

JCI Insight. 2019 Jan 24;4(2). pii: 123837. doi: 10.1172/jci.insight.123837. [Epub ahead of print]


A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications.

Gobin M, Nazarov PV, Warta R, Timmer M, Reifenberger G, Felsberg J, Vallar L, Chalmers AJ, Herold-Mende CC, Goldbrunner R, Niclou SP, Van Dyck E.

Cancer Res. 2019 Mar 15;79(6):1226-1238. doi: 10.1158/0008-5472.CAN-18-2076. Epub 2019 Jan 23.


Location-Dependent Patient Outcome and Recurrence Patterns in IDH1-Wildtype Glioblastoma.

Jungk C, Warta R, Mock A, Friauf S, Hug B, Capper D, Abdollahi A, Debus J, Bendszus M, von Deimling A, Unterberg A, Herold-Mende C.

Cancers (Basel). 2019 Jan 21;11(1). pii: E122. doi: 10.3390/cancers11010122.


N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines.

Zhou J, Negi A, Mirallai SI, Warta R, Herold-Mende C, Carty MP, Ye XS, Murphy PV.

Bioorg Chem. 2019 Mar;84:418-433. doi: 10.1016/j.bioorg.2018.12.003. Epub 2018 Dec 4.


Identification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma.

Dao Trong P, Rösch S, Mairbäurl H, Pusch S, Unterberg A, Herold-Mende C, Warta R.

Int J Mol Sci. 2018 Sep 25;19(10). pii: E2903. doi: 10.3390/ijms19102903.


Zeb1 potentiates genome-wide gene transcription with Lef1 to promote glioblastoma cell invasion.

Rosmaninho P, Mükusch S, Piscopo V, Teixeira V, Raposo AA, Warta R, Bennewitz R, Tang Y, Herold-Mende C, Stifani S, Momma S, Castro DS.

EMBO J. 2018 Aug 1;37(15). pii: e97115. doi: 10.15252/embj.201797115. Epub 2018 Jun 14.


MetaboDiff: an R package for differential metabolomic analysis.

Mock A, Warta R, Dettling S, Brors B, Jäger D, Herold-Mende C.

Bioinformatics. 2018 Oct 1;34(19):3417-3418. doi: 10.1093/bioinformatics/bty344.


Comparison of the RGD Motif-Containing αvβ6 Integrin-Binding Peptides SFLAP3 and SFITGv6 for Diagnostic Application in HNSCC.

Roesch S, Lindner T, Sauter M, Loktev A, Flechsig P, Müller M, Mier W, Warta R, Dyckhoff G, Herold-Mende C, Haberkorn U, Altmann A.

J Nucl Med. 2018 Nov;59(11):1679-1685. doi: 10.2967/jnumed.118.210013. Epub 2018 Apr 19.


Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma.

Dettling S, Stamova S, Warta R, Schnölzer M, Rapp C, Rathinasamy A, Reuss D, Pocha K, Roesch S, Jungk C, Warnken U, Eckstein V, Grabe N, Schramm C, Weigand MA, von Deimling A, Unterberg A, Beckhove P, Herold-Mende C.

Clin Cancer Res. 2018 Jun 15;24(12):2951-2962. doi: 10.1158/1078-0432.CCR-17-1839. Epub 2018 Mar 21.


The design, production and clinical application of 3D patient-specific implants with drilling guides for acetabular surgery.

Merema BJ, Kraeima J, Ten Duis K, Wendt KW, Warta R, Vos E, Schepers RH, Witjes MJH, IJpma FFA.

Injury. 2017 Nov;48(11):2540-2547. doi: 10.1016/j.injury.2017.08.059. Epub 2017 Aug 30.


Helping EGFR inhibition to block cancer.

Warta R, Herold-Mende C.

Nat Neurosci. 2017 Jul 26;20(8):1035-1037. doi: 10.1038/nn.4605. No abstract available.


Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display.

Altmann A, Sauter M, Roesch S, Mier W, Warta R, Debus J, Dyckhoff G, Herold-Mende C, Haberkorn U.

Clin Cancer Res. 2017 Aug 1;23(15):4170-4180. doi: 10.1158/1078-0432.CCR-16-3217. Epub 2017 May 3.


Identification of T cell target antigens in glioblastoma stem-like cells using an integrated proteomics-based approach in patient specimens.

Rapp C, Warta R, Stamova S, Nowrouzi A, Geisenberger C, Gal Z, Roesch S, Dettling S, Juenger S, Bucur M, Jungk C, DaoTrong P, Ahmadi R, Sahm F, Reuss D, Fermi V, Herpel E, Eckstein V, Grabe N, Schramm C, Weigand MA, Debus J, von Deimling A, Unterberg A, Abdollahi A, Beckhove P, Herold-Mende C.

Acta Neuropathol. 2017 Aug;134(2):297-316. doi: 10.1007/s00401-017-1702-1. Epub 2017 Mar 22.


Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas.

Kohanbash G, Carrera DA, Shrivastav S, Ahn BJ, Jahan N, Mazor T, Chheda ZS, Downey KM, Watchmaker PB, Beppler C, Warta R, Amankulor NA, Herold-Mende C, Costello JF, Okada H.

J Clin Invest. 2017 Apr 3;127(4):1425-1437. doi: 10.1172/JCI90644. Epub 2017 Mar 20.


Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone.

Jungk C, Mock A, Exner J, Geisenberger C, Warta R, Capper D, Abdollahi A, Friauf S, Lahrmann B, Grabe N, Beckhove P, von Deimling A, Unterberg A, Herold-Mende C.

BMC Med. 2016 Oct 26;14(1):170.


LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients.

Mock A, Geisenberger C, Orlik C, Warta R, Schwager C, Jungk C, Dutruel C, Geiselhart L, Weichenhan D, Zucknick M, Nied AK, Friauf S, Exner J, Capper D, Hartmann C, Lahrmann B, Grabe N, Debus J, von Deimling A, Popanda O, Plass C, Unterberg A, Abdollahi A, Schmezer P, Herold-Mende C.

Int J Cancer. 2016 Jul 15;139(2):424-32. doi: 10.1002/ijc.30069. Epub 2016 Mar 18.


Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade.

Schmidt M, Mock A, Jungk C, Sahm F, Ull AT, Warta R, Lamszus K, Gousias K, Ketter R, Roesch S, Rapp C, Schefzyk S, Urbschat S, Lahrmann B, Kessler AF, Löhr M, Senft C, Grabe N, Reuss D, Beckhove P, Westphal M, von Deimling A, Unterberg A, Simon M, Herold-Mende C.

Oncotarget. 2016 Mar 22;7(12):14551-68. doi: 10.18632/oncotarget.7396.


Prognostic factors and long-term survival in surgically treated brain metastases from non-small cell lung cancer.

Enders F, Geisenberger C, Jungk C, Bermejo JL, Warta R, von Deimling A, Herold-Mende C, Unterberg A.

Clin Neurol Neurosurg. 2016 Mar;142:72-80. doi: 10.1016/j.clineuro.2016.01.011. Epub 2016 Jan 14.


Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma.

Tawk B, Schwager C, Deffaa O, Dyckhoff G, Warta R, Linge A, Krause M, Weichert W, Baumann M, Herold-Mende C, Debus J, Abdollahi A.

Radiother Oncol. 2016 Feb;118(2):350-8. doi: 10.1016/j.radonc.2015.11.027. Epub 2015 Dec 19.


Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma.

Reuter T, Warta R, Theile D, Meid AD, Rigalli JP, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1141-50. doi: 10.1007/s00210-015-1150-1. Epub 2015 Jul 4.


Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients.

Mock A, Warta R, Geisenberger C, Bischoff R, Schulte A, Lamszus K, Stadler V, Felgenhauer T, Schichor C, Schwartz C, Matschke J, Jungk C, Ahmadi R, Sahm F, Capper D, Glass R, Tonn JC, Westphal M, von Deimling A, Unterberg A, Bermejo JL, Herold-Mende C.

Oncotarget. 2015 May 30;6(15):13579-90.


Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain.

Geisenberger C, Mock A, Warta R, Rapp C, Schwager C, Korshunov A, Nied AK, Capper D, Brors B, Jungk C, Jones D, Collins VP, Ichimura K, Bäcklund LM, Schnabel E, Mittelbron M, Lahrmann B, Zheng S, Verhaak RG, Grabe N, Pfister SM, Hartmann C, von Deimling A, Debus J, Unterberg A, Abdollahi A, Herold-Mende C.

Acta Neuropathol. 2015 Sep;130(3):419-34. doi: 10.1007/s00401-015-1427-y. Epub 2015 May 1.


Association of drug transporter expression with mortality and progression-free survival in stage IV head and neck squamous cell carcinoma.

Warta R, Theile D, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Weiss J, Dyckhoff G.

PLoS One. 2014 Oct 2;9(9):e108908. doi: 10.1371/journal.pone.0108908. eCollection 2014.


Reduced promoter methylation and increased expression of CSPG4 negatively influences survival of HNSCC patients.

Warta R, Herold-Mende C, Chaisaingmongkol J, Popanda O, Mock A, Mogler C, Osswald F, Herpel E, Küstner S, Eckstein V, Plass C, Plinkert P, Schmezer P, Dyckhoff G.

Int J Cancer. 2014 Dec 1;135(11):2727-34. doi: 10.1002/ijc.28906. Epub 2014 Apr 26.


Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma.

Theile D, Gal Z, Warta R, Rigalli JP, Lahrmann B, Grabe N, Herold-Mende C, Dyckhoff G, Weiss J.

Cancer Biol Ther. 2014 Apr;15(4):436-42. doi: 10.4161/cbt.27632. Epub 2014 Jan 21.


Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma.

Chaisaingmongkol J, Popanda O, Warta R, Dyckhoff G, Herpel E, Geiselhart L, Claus R, Lasitschka F, Campos B, Oakes CC, Bermejo JL, Herold-Mende C, Plass C, Schmezer P.

Oncogene. 2012 Dec 6;31(49):5108-16. doi: 10.1038/onc.2011.660. Epub 2012 Jan 30.


Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas.

Campos B, Warta R, Chaisaingmongkol J, Geiselhart L, Popanda O, Hartmann C, von Deimling A, Unterberg A, Plass C, Schmezer P, Herold-Mende C.

Int J Cancer. 2012 Oct 15;131(8):1963-8. doi: 10.1002/ijc.27446. Epub 2012 Mar 8.


Carbohydrate antigen 19-9 in saliva: possible preoperative marker of malignancy in parotid tumors.

Dyckhoff G, Warta R, Gonnermann A, Plinkert PK, Flechtenmacher C, Volkmann M.

Otolaryngol Head Neck Surg. 2011 Nov;145(5):772-7. doi: 10.1177/0194599811414512. Epub 2011 Jul 11.


Disinfection of bacterial biofilms in pilot-scale cooling tower systems.

Liu Y, Zhang W, Sileika T, Warta R, Cianciotto NP, Packman AI.

Biofouling. 2011 Apr;27(4):393-402. doi: 10.1080/08927014.2011.577525.


Electron energy loss spectroscopy elucidates the elusive darkening of zinc potassium chromate in Georges Seurat's A Sunday on La Grande Jatte--1884.

Casadio F, Xie S, Rukes SC, Myers B, Gray KA, Warta R, Fiedler I.

Anal Bioanal Chem. 2011 Mar;399(9):2909-20. doi: 10.1007/s00216-010-4264-9. Epub 2010 Oct 16.


Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation.

Beckhove P, Warta R, Lemke B, Stoycheva D, Momburg F, Schnölzer M, Warnken U, Schmitz-Winnenthal H, Ahmadi R, Dyckhoff G, Bucur M, Jünger S, Schueler T, Lennerz V, Woelfel T, Unterberg A, Herold-Mende C.

J Clin Invest. 2010 Jun;120(6):2230-42. doi: 10.1172/JCI37646. Epub 2010 May 10.


Role of bacterial adhesion in the microbial ecology of biofilms in cooling tower systems.

Liu Y, Zhang W, Sileika T, Warta R, Cianciotto NP, Packman A.

Biofouling. 2009;25(3):241-53. doi: 10.1080/08927010802713414.

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