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Items: 46

1.

IONIS-PKKRx a Novel Antisense Inhibitor of Prekallikrein and Bradykinin Production.

Ferrone JD, Bhattacharjee G, Revenko AS, Zanardi TA, Warren MS, Derosier FJ, Viney NJ, Pham NC, Kaeser GE, Baker BF, Schneider E, Hughes SG, Monia BP, MacLeod AR.

Nucleic Acid Ther. 2019 Apr;29(2):82-91. doi: 10.1089/nat.2018.0754. Epub 2019 Feb 28.

2.

Nurse Satisfaction With Medical Emergency Team Nurses: A 3-Year Study.

Halupa CM, Halupa MS, Warren MS.

Dimens Crit Care Nurs. 2018 Jul/Aug;37(4):217-224. doi: 10.1097/DCC.0000000000000307.

PMID:
29847434
3.

Assessment of the Drug Interaction Potential of Unconjugated and GalNAc3-Conjugated 2'-MOE-ASOs.

Shemesh CS, Yu RZ, Warren MS, Liu M, Jahic M, Nichols B, Post N, Lin S, Norris DA, Hurh E, Huang J, Watanabe T, Henry SP, Wang Y.

Mol Ther Nucleic Acids. 2017 Dec 15;9:34-47. doi: 10.1016/j.omtn.2017.08.012. Epub 2017 Aug 30.

4.

Lack of Interactions Between an Antisense Oligonucleotide with 2'-O-(2-Methoxyethyl) Modifications and Major Drug Transporters.

Yu RZ, Warren MS, Watanabe T, Nichols B, Jahic M, Huang J, Burkey J, Geary RS, Henry SP, Wang Y.

Nucleic Acid Ther. 2016 Apr;26(2):111-7. doi: 10.1089/nat.2015.0588. Epub 2016 Mar 9.

PMID:
26959999
5.
6.

Impact on creatinine renal clearance by the interplay of multiple renal transporters: a case study with INCB039110.

Zhang Y, Warren MS, Zhang X, Diamond S, Williams B, Punwani N, Huang J, Huang Y, Yeleswaram S.

Drug Metab Dispos. 2015 Apr;43(4):485-9. doi: 10.1124/dmd.114.060673. Epub 2015 Jan 20.

PMID:
25605813
7.

Cosmology with void-galaxy correlations.

Hamaus N, Wandelt BD, Sutter PM, Lavaux G, Warren MS.

Phys Rev Lett. 2014 Jan 31;112(4):041304. Epub 2014 Jan 29.

PMID:
24580436
8.

High-level pacidamycin resistance in Pseudomonas aeruginosa is mediated by an opp oligopeptide permease encoded by the opp-fabI operon.

Mistry A, Warren MS, Cusick JK, Karkhoff-Schweizer RR, Lomovskaya O, Schweizer HP.

Antimicrob Agents Chemother. 2013 Nov;57(11):5565-71. doi: 10.1128/AAC.01198-13. Epub 2013 Aug 26.

9.

Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo.

Gil-Henn H, Patsialou A, Wang Y, Warren MS, Condeelis JS, Koleske AJ.

Oncogene. 2013 May 23;32(21):2622-30. doi: 10.1038/onc.2012.284. Epub 2012 Jul 9.

10.

Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity.

Gourley SL, Olevska A, Warren MS, Taylor JR, Koleske AJ.

J Neurosci. 2012 Feb 15;32(7):2314-23. doi: 10.1523/JNEUROSCI.2730-11.2012.

11.

Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior.

Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ.

J Neurosci. 2012 Feb 22;32(8):2824-34. doi: 10.1523/JNEUROSCI.3942-11.2012.

12.

A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial.

Weber MA, Black H, Bakris G, Krum H, Linas S, Weiss R, Linseman JV, Wiens BL, Warren MS, Lindholm LH.

Lancet. 2009 Oct 24;374(9699):1423-31. doi: 10.1016/S0140-6736(09)61500-2. Epub 2009 Sep 11.

PMID:
19748665
13.

Arbaclofen placarbil, a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen.

Lal R, Sukbuntherng J, Tai EH, Upadhyay S, Yao F, Warren MS, Luo W, Bu L, Nguyen S, Zamora J, Peng G, Dias T, Bao Y, Ludwikow M, Phan T, Scheuerman RA, Yan H, Gao M, Wu QQ, Annamalai T, Raillard SP, Koller K, Gallop MA, Cundy KC.

J Pharmacol Exp Ther. 2009 Sep;330(3):911-21. doi: 10.1124/jpet.108.149773. Epub 2009 Jun 5.

PMID:
19502531
14.

Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human.

Warren MS, Zerangue N, Woodford K, Roberts LM, Tate EH, Feng B, Li C, Feuerstein TJ, Gibbs J, Smith B, de Morais SM, Dower WJ, Koller KJ.

Pharmacol Res. 2009 Jun;59(6):404-13. doi: 10.1016/j.phrs.2009.02.007. Epub 2009 Feb 24.

PMID:
19429473
15.

Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers.

Lo PC, Chen J, Stefflova K, Warren MS, Navab R, Bandarchi B, Mullins S, Tsao M, Cheng JD, Zheng G.

J Med Chem. 2009 Jan 22;52(2):358-68. doi: 10.1021/jm801052f.

16.

Minimum viable metapopulation size, extinction debt, and the conservation of a declining species.

Bulman CR, Wilson RJ, Holt AR, Gálvez Bravo L, Early RI, Warren MS, Thomas CD.

Ecol Appl. 2007 Jul;17(5):1460-73.

PMID:
17708221
17.

PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure.

Reiken S, Lacampagne A, Zhou H, Kherani A, Lehnart SE, Ward C, Huang F, Gaburjakova M, Gaburjakova J, Rosemblit N, Warren MS, He KL, Yi GH, Wang J, Burkhoff D, Vassort G, Marks AR.

J Cell Biol. 2003 Mar 17;160(6):919-28. Epub 2003 Mar 10.

19.

Rapid responses of British butterflies to opposing forces of climate and habitat change.

Warren MS, Hill JK, Thomas JA, Asher J, Fox R, Huntley B, Roy DB, Telfer MG, Jeffcoate S, Harding P, Jeffcoate G, Willis SG, Greatorex-Davies JN, Moss D, Thomas CD.

Nature. 2001 Nov 1;414(6859):65-9.

PMID:
11689943
20.

MexXY-OprM efflux pump is required for antagonism of aminoglycosides by divalent cations in Pseudomonas aeruginosa.

Mao W, Warren MS, Lee A, Mistry A, Lomovskaya O.

Antimicrob Agents Chemother. 2001 Jul;45(7):2001-7.

21.

Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance.

Lee MD, Galazzo JL, Staley AL, Lee JC, Warren MS, Fuernkranz H, Chamberland S, Lomovskaya O, Miller GH.

Farmaco. 2001 Jan-Feb;56(1-2):81-5. Review.

PMID:
11347972
22.

Results of targeted anti-tumor necrosis factor therapy with etanercept (ENBREL) in patients with advanced heart failure.

Bozkurt B, Torre-Amione G, Warren MS, Whitmore J, Soran OZ, Feldman AM, Mann DL.

Circulation. 2001 Feb 27;103(8):1044-7.

PMID:
11222463
23.

Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy.

Lomovskaya O, Warren MS, Lee A, Galazzo J, Fronko R, Lee M, Blais J, Cho D, Chamberland S, Renau T, Leger R, Hecker S, Watkins W, Hoshino K, Ishida H, Lee VJ.

Antimicrob Agents Chemother. 2001 Jan;45(1):105-16.

24.

Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance.

Lee A, Mao W, Warren MS, Mistry A, Hoshino K, Okumura R, Ishida H, Lomovskaya O.

J Bacteriol. 2000 Jun;182(11):3142-50.

25.

Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa.

Lomovskaya O, Lee A, Hoshino K, Ishida H, Mistry A, Warren MS, Boyer E, Chamberland S, Lee VJ.

Antimicrob Agents Chemother. 1999 Jun;43(6):1340-6.

26.

Therapeutic effect of zafirlukast as monotherapy in steroid-naive patients with severe persistent asthma.

Kemp JP, Minkwitz MC, Bonuccelli CM, Warren MS.

Chest. 1999 Feb;115(2):336-42.

PMID:
10027429
27.

Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors.

Boger DL, Kochanny MJ, Cai H, Wyatt D, Kitos PA, Warren MS, Ramcharan J, Gooljarsingh LT, Benkovic SJ.

Bioorg Med Chem. 1998 Jun;6(6):643-59. No abstract available.

PMID:
9681131
28.

Multisubstrate analogue based on 5,8,10-trideazafolate.

Boger DL, Haynes NE, Warren MS, Ramcharan J, Kitos PA, Benkovic SJ.

Bioorg Med Chem. 1997 Sep;5(9):1853-7. No abstract available.

PMID:
9354241
29.

Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): an effective inhibitor of glycinamide ribonucleotide transformylase.

Boger DL, Haynes NE, Warren MS, Ramcharan J, Marolewski AE, Kitos PA, Benkovic SJ.

Bioorg Med Chem. 1997 Sep;5(9):1847-52.

PMID:
9354240
30.
31.

Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase.

Boger DL, Haynes NE, Warren MS, Gooljarsingh LT, Ramcharan J, Kitos PA, Benkovic SJ.

Bioorg Med Chem. 1997 Sep;5(9):1831-8. No abstract available.

PMID:
9354238
32.

10-Formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase.

Boger DL, Haynes NE, Kitos PA, Warren MS, Ramcharan J, Marolewski AE, Benkovic SJ.

Bioorg Med Chem. 1997 Sep;5(9):1817-30.

PMID:
9354237
33.

Formyl phosphate: a proposed intermediate in the reaction catalyzed by Escherichia coli PurT GAR transformylase.

Marolewski AE, Mattia KM, Warren MS, Benkovic SJ.

Biochemistry. 1997 Jun 3;36(22):6709-16.

PMID:
9184151
34.

Assembly of an active enzyme by the linkage of two protein modules.

Nixon AE, Warren MS, Benkovic SJ.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1069-73.

35.
36.

A rapid screen of active site mutants in glycinamide ribonucleotide transformylase.

Warren MS, Marolewski AE, Benkovic SJ.

Biochemistry. 1996 Jul 9;35(27):8855-62.

PMID:
8688421
37.

Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.

Klein C, Chen P, Arevalo JH, Stura EA, Marolewski A, Warren MS, Benkovic SJ, Wilson IA.

J Mol Biol. 1995 May 26;249(1):153-75.

PMID:
7776369
38.

Distributions of occupied and vacant butterfly habitats in fragmented landscapes.

Thomas CD, Thomas JA, Warren MS.

Oecologia. 1992 Dec;92(4):563-567. doi: 10.1007/BF00317850.

PMID:
28313229
39.

Analysis of hydride transfer and cofactor fluorescence decay in mutants of dihydrofolate reductase: possible evidence for participation of enzyme molecular motions in catalysis.

Farnum MF, Magde D, Howell EE, Hirai JT, Warren MS, Grimsley JK, Kraut J.

Biochemistry. 1991 Dec 10;30(49):11567-79.

PMID:
1747376
40.

Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.

Warren MS, Brown KA, Farnum MF, Howell EE, Kraut J.

Biochemistry. 1991 Nov 19;30(46):11092-103.

PMID:
1932031
41.
42.
43.

Construction of an altered proton donation mechanism in Escherichia coli dihydrofolate reductase.

Howell EE, Warren MS, Booth CL, Villafranca JE, Kraut J.

Biochemistry. 1987 Dec 29;26(26):8591-8.

PMID:
2894842
44.
45.

Functional role of aspartic acid-27 in dihydrofolate reductase revealed by mutagenesis.

Howell EE, Villafranca JE, Warren MS, Oatley SJ, Kraut J.

Science. 1986 Mar 7;231(4742):1123-8.

PMID:
3511529
46.

Chronic hepatitis in patients with hemophilia A: histologic studies in patients with intermittently abnormal liver function tests.

White GC 2nd, Zeitler KD, Lesesne HR, McMillan CW, Warren MS, Roberts HR, Blatt PM.

Blood. 1982 Dec;60(6):1259-62.

PMID:
6814549

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