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Items: 1 to 50 of 174

1.

Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end-stage renal disease.

Yamanouchi M, Skupien J, Niewczas MA, Smiles AM, Doria A, Stanton RC, Galecki AT, Duffin KL, Pullen N, Breyer MD, Bonventre JV, Warram JH, Krolewski AS.

Kidney Int. 2017 Jul;92(1):258-266. doi: 10.1016/j.kint.2017.02.010. Epub 2017 Apr 7.

2.

Fast renal decline to end-stage renal disease: an unrecognized feature of nephropathy in diabetes.

Krolewski AS, Skupien J, Rossing P, Warram JH.

Kidney Int. 2017 Jun;91(6):1300-1311. doi: 10.1016/j.kint.2016.10.046. Epub 2017 Mar 31. Review.

3.

Patterns of Estimated Glomerular Filtration Rate Decline Leading to End-Stage Renal Disease in Type 1 Diabetes.

Skupien J, Warram JH, Smiles AM, Stanton RC, Krolewski AS.

Diabetes Care. 2016 Dec;39(12):2262-2269. Epub 2016 Sep 19.

4.

Increased plasma kidney injury molecule-1 suggests early progressive renal decline in non-proteinuric patients with type 1 diabetes.

Nowak N, Skupien J, Niewczas MA, Yamanouchi M, Major M, Croall S, Smiles A, Warram JH, Bonventre JV, Krolewski AS.

Kidney Int. 2016 Feb;89(2):459-67.

5.

Cardiac autonomic neuropathy and early progressive renal decline in patients with nonmacroalbuminuric type 1 diabetes.

Orlov S, Cherney DZ, Pop-Busui R, Lovblom LE, Ficociello LH, Smiles AM, Warram JH, Krolewski AS, Perkins BA.

Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1136-44. doi: 10.2215/CJN.11441114. Epub 2015 Jun 19.

6.

Improved glycemic control and risk of ESRD in patients with type 1 diabetes and proteinuria.

Skupien J, Warram JH, Smiles A, Galecki A, Stanton RC, Krolewski AS.

J Am Soc Nephrol. 2014 Dec;25(12):2916-25. doi: 10.1681/ASN.2013091002. Epub 2014 Jun 5.

7.

Synergism between circulating tumor necrosis factor receptor 2 and HbA(1c) in determining renal decline during 5-18 years of follow-up in patients with type 1 diabetes and proteinuria.

Skupien J, Warram JH, Niewczas MA, Gohda T, Malecki M, Mychaleckyj JC, Galecki AT, Krolewski AS.

Diabetes Care. 2014 Sep;37(9):2601-8. doi: 10.2337/dc13-1983. Epub 2014 Jun 4.

8.

Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.

Niewczas MA, Sirich TL, Mathew AV, Skupien J, Mohney RP, Warram JH, Smiles A, Huang X, Walker W, Byun J, Karoly ED, Kensicki EM, Berry GT, Bonventre JV, Pennathur S, Meyer TW, Krolewski AS.

Kidney Int. 2014 May;85(5):1214-24. doi: 10.1038/ki.2013.497. Epub 2014 Jan 15.

9.

Early progressive renal decline precedes the onset of microalbuminuria and its progression to macroalbuminuria.

Krolewski AS, Niewczas MA, Skupien J, Gohda T, Smiles A, Eckfeldt JH, Doria A, Warram JH.

Diabetes Care. 2014;37(1):226-34. doi: 10.2337/dc13-0985. Epub 2013 Aug 12.

10.

Cystatin-based estimated GFR versus creatinine-based and creatinine- and cystatin-based estimated GFR for ESRD and mortality risk in diabetes.

Skupien J, Warram JH, Groop PH, Krolewski AS.

Am J Kidney Dis. 2013 Jul;62(1):184-6. doi: 10.1053/j.ajkd.2013.03.029. Epub 2013 May 17. No abstract available.

PMID:
23684753
11.

Family-based association analysis confirms the role of the chromosome 9q21.32 locus in the susceptibility of diabetic nephropathy.

Pezzolesi MG, Jeong J, Smiles AM, Skupien J, Mychaleckyj JC, Rich SS, Warram JH, Krolewski AS.

PLoS One. 2013;8(3):e60301. doi: 10.1371/journal.pone.0060301. Epub 2013 Mar 29.

12.

Transcriptome analysis of proximal tubular cells (HK-2) exposed to urines of type 1 diabetes patients at risk of early progressive renal function decline.

Wanic K, Krolewski B, Ju W, Placha G, Niewczas MA, Walker W, Warram JH, Kretzler M, Krolewski AS.

PLoS One. 2013;8(3):e57751. doi: 10.1371/journal.pone.0057751. Epub 2013 Mar 7.

13.

Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type 1 diabetes.

Merchant ML, Niewczas MA, Ficociello LH, Lukenbill JA, Wilkey DW, Li M, Khundmiri SJ, Warram JH, Krolewski AS, Klein JB.

Kidney Int. 2013 Jun;83(6):1177-84. doi: 10.1038/ki.2013.8. Epub 2013 Mar 6.

14.

Serum concentration of cystatin C and risk of end-stage renal disease in diabetes.

Krolewski AS, Warram JH, Forsblom C, Smiles AM, Thorn L, Skupien J, Harjutsalo V, Stanton R, Eckfeldt JH, Inker LA, Groop PH.

Diabetes Care. 2012 Nov;35(11):2311-6. doi: 10.2337/dc11-2220. Epub 2012 Jul 30.

15.

The early decline in renal function in patients with type 1 diabetes and proteinuria predicts the risk of end-stage renal disease.

Skupien J, Warram JH, Smiles AM, Niewczas MA, Gohda T, Pezzolesi MG, Cantarovich D, Stanton R, Krolewski AS.

Kidney Int. 2012 Sep;82(5):589-97. doi: 10.1038/ki.2012.189. Epub 2012 May 23.

16.

Elevated urinary excretion of immunoglobulins in nonproteinuric patients with type 1 diabetes.

Gohda T, Walker WH, Wolkow P, Lee JE, Warram JH, Krolewski AS, Niewczas MA.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F157-62. doi: 10.1152/ajprenal.00443.2011. Epub 2012 Apr 18.

17.

Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes.

Gohda T, Niewczas MA, Ficociello LH, Walker WH, Skupien J, Rosetti F, Cullere X, Johnson AC, Crabtree G, Smiles AM, Mayadas TN, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2012 Mar;23(3):516-24. doi: 10.1681/ASN.2011060628. Epub 2012 Jan 19.

18.

Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes.

Niewczas MA, Gohda T, Skupien J, Smiles AM, Walker WH, Rosetti F, Cullere X, Eckfeldt JH, Doria A, Mayadas TN, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2012 Mar;23(3):507-15. doi: 10.1681/ASN.2011060627. Epub 2012 Jan 19.

19.

A Bayesian population analysis of the development of type 2 diabetes in the offspring of diabetic parents.

Lin CW, Warram JH, Veng-Pedersen P.

J Pharmacokinet Pharmacodyn. 2011 Oct;38(5):563-79. doi: 10.1007/s10928-011-9208-2. Epub 2011 Aug 11.

PMID:
21833670
20.

An intergenic region on chromosome 13q33.3 is associated with the susceptibility to kidney disease in type 1 and 2 diabetes.

Pezzolesi MG, Poznik GD, Skupien J, Smiles AM, Mychaleckyj JC, Rich SS, Warram JH, Krolewski AS.

Kidney Int. 2011 Jul;80(1):105-11. doi: 10.1038/ki.2011.64. Epub 2011 Mar 16.

21.

Risk for ESRD in type 1 diabetes remains high despite renoprotection.

Rosolowsky ET, Skupien J, Smiles AM, Niewczas M, Roshan B, Stanton R, Eckfeldt JH, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2011 Mar;22(3):545-53. doi: 10.1681/ASN.2010040354. Epub 2011 Feb 25.

22.

Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes.

Kure M, Pezzolesi MG, Poznik GD, Katavetin P, Skupien J, Dunn JS, Mychaleckyj JC, Warram JH, Krolewski AS.

Mol Genet Metab. 2011 May;103(1):60-5. doi: 10.1016/j.ymgme.2011.01.001. Epub 2011 Jan 14.

23.

Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase.

Vaidya VS, Niewczas MA, Ficociello LH, Johnson AC, Collings FB, Warram JH, Krolewski AS, Bonventre JV.

Kidney Int. 2011 Feb;79(4):464-70. doi: 10.1038/ki.2010.404. Epub 2010 Oct 27.

24.

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.

Liew CW, Bochenski J, Kawamori D, Hu J, Leech CA, Wanic K, Malecki M, Warram JH, Qi L, Krolewski AS, Kulkarni RN.

J Clin Invest. 2010 Aug;120(8):2876-88. doi: 10.1172/JCI36849. Epub 2010 Jul 1.

25.

Insights to the genetics of diabetic nephropathy through a genome-wide association study of the GoKinD collection.

Pezzolesi MG, Skupien J, Mychaleckyj JC, Warram JH, Krolewski AS.

Semin Nephrol. 2010 Mar;30(2):126-40. doi: 10.1016/j.semnephrol.2010.01.004. Review.

26.

High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up.

Ficociello LH, Rosolowsky ET, Niewczas MA, Maselli NJ, Weinberg JM, Aschengrau A, Eckfeldt JH, Stanton RC, Galecki AT, Doria A, Warram JH, Krolewski AS.

Diabetes Care. 2010 Jun;33(6):1337-43. doi: 10.2337/dc10-0227. Epub 2010 Mar 23.

27.

Genetic analysis of albuminuria in aging mice and concordance with loci for human diabetic nephropathy found in a genome-wide association scan.

Tsaih SW, Pezzolesi MG, Yuan R, Warram JH, Krolewski AS, Korstanje R.

Kidney Int. 2010 Feb;77(3):201-10. doi: 10.1038/ki.2009.434. Epub 2009 Nov 18.

28.

In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria.

Perkins BA, Ficociello LH, Roshan B, Warram JH, Krolewski AS.

Kidney Int. 2010 Jan;77(1):57-64. doi: 10.1038/ki.2009.399.

29.

Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.

Pezzolesi MG, Katavetin P, Kure M, Poznik GD, Skupien J, Mychaleckyj JC, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Nov;58(11):2698-702. doi: 10.2337/db09-0641. Epub 2009 Aug 3.

30.

Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria.

Merchant ML, Perkins BA, Boratyn GM, Ficociello LH, Wilkey DW, Barati MT, Bertram CC, Page GP, Rovin BH, Warram JH, Krolewski AS, Klein JB.

J Am Soc Nephrol. 2009 Sep;20(9):2065-74. doi: 10.1681/ASN.2008121233. Epub 2009 Jul 30.

31.

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB; DCCT/EDIC Research Group, Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Jun;58(6):1403-10. doi: 10.2337/db08-1514. Epub 2009 Feb 27.

32.

Renal hyperfiltration and the development of microalbuminuria in type 1 diabetes.

Ficociello LH, Perkins BA, Roshan B, Weinberg JM, Aschengrau A, Warram JH, Krolewski AS.

Diabetes Care. 2009 May;32(5):889-93. doi: 10.2337/dc08-1560. Epub 2009 Feb 5.

33.

Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes.

Niewczas MA, Ficociello LH, Johnson AC, Walker W, Rosolowsky ET, Roshan B, Warram JH, Krolewski AS.

Clin J Am Soc Nephrol. 2009 Jan;4(1):62-70. doi: 10.2215/CJN.03010608. Epub 2008 Dec 10.

34.

Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes.

Doria A, Wojcik J, Xu R, Gervino EV, Hauser TH, Johnstone MT, Nolan D, Hu FB, Warram JH.

JAMA. 2008 Nov 26;300(20):2389-97. doi: 10.1001/jama.2008.649.

35.

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

Cooper JD, Smyth DJ, Smiles AM, Plagnol V, Walker NM, Allen JE, Downes K, Barrett JC, Healy BC, Mychaleckyj JC, Warram JH, Todd JA.

Nat Genet. 2008 Dec;40(12):1399-401. doi: 10.1038/ng.249. Epub 2008 Nov 2.

36.

Between hyperfiltration and impairment: demystifying early renal functional changes in diabetic nephropathy.

Rosolowsky ET, Niewczas MA, Ficociello LH, Perkins BA, Warram JH, Krolewski AS.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S46-53. doi: 10.1016/j.diabres.2008.09.018. Epub 2008 Oct 11. Review.

PMID:
18849087
37.
38.

High-density single nucleotide polymorphism genome-wide linkage scan for susceptibility genes for diabetic nephropathy in type 1 diabetes: discordant sibpair approach.

Rogus JJ, Poznik GD, Pezzolesi MG, Smiles AM, Dunn J, Walker W, Wanic K, Moczulski D, Canani L, Araki S, Makita Y, Warram JH, Krolewski AS.

Diabetes. 2008 Sep;57(9):2519-26. doi: 10.2337/db07-1086. Epub 2008 Jun 16.

39.

High-normal serum uric acid is associated with impaired glomerular filtration rate in nonproteinuric patients with type 1 diabetes.

Rosolowsky ET, Ficociello LH, Maselli NJ, Niewczas MA, Binns AL, Roshan B, Warram JH, Krolewski AS.

Clin J Am Soc Nephrol. 2008 May;3(3):706-13. doi: 10.2215/CJN.04271007. Epub 2008 Feb 13.

40.

Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics.

Wolkow PP, Niewczas MA, Perkins B, Ficociello LH, Lipinski B, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2008 Apr;19(4):789-97. doi: 10.1681/ASN.2007050556. Epub 2008 Feb 6.

41.

Nephropathy in type 1 diabetes is diminished in carriers of HLA-DRB1*04: the genetics of kidneys in diabetes (GoKinD) study.

Cordovado SK, Zhao Y, Warram JH, Gong H, Anderson KL, Hendrix MM, Hancock LN, Cleary PA, Mueller PW.

Diabetes. 2008 Feb;57(2):518-22. Epub 2007 Nov 26.

42.

Determinants of progression from microalbuminuria to proteinuria in patients who have type 1 diabetes and are treated with angiotensin-converting enzyme inhibitors.

Ficociello LH, Perkins BA, Silva KH, Finkelstein DM, Ignatowska-Switalska H, Gaciong Z, Cupples LA, Aschengrau A, Warram JH, Krolewski AS.

Clin J Am Soc Nephrol. 2007 May;2(3):461-9. Epub 2007 Mar 27.

43.

Lack of association between polymorphisms in the gene encoding protein tyrosine phosphatase 1B (PTPN1) and risk of Type 2 diabetes.

Wanic K, Malecki MT, Klupa T, Warram JH, Sieradzki J, Krolewski AS.

Diabet Med. 2007 Jun;24(6):650-5. Epub 2007 Apr 2.

PMID:
17403124
44.

Identification of a locus modulating serum C-reactive protein levels on chromosome 5p15.

Keenan HA, Poznik GD, Varo N, Schneider J, Almasy L, Warram JH, Duggirala R, Schoenbeck U, Krolewski AS, Doria A.

Atherosclerosis. 2008 Feb;196(2):863-70. Epub 2007 Mar 7.

45.

Microalbuminuria and the risk for early progressive renal function decline in type 1 diabetes.

Perkins BA, Ficociello LH, Ostrander BE, Silva KH, Weinberg J, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2007 Apr;18(4):1353-61. Epub 2007 Feb 28.

46.

A genome-wide linkage scan for genes controlling variation in renal function estimated by serum cystatin C levels in extended families with type 2 diabetes.

Placha G, Poznik GD, Dunn J, Smiles A, Krolewski B, Glew T, Puppala S, Schneider J, Rogus JJ, Rich SS, Duggirala R, Warram JH, Krolewski AS.

Diabetes. 2006 Dec;55(12):3358-65.

47.

A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus.

Ng DP, Placha G, Choo S, Chia KS, Warram JH, Krolewski AS.

Diabetes. 2006 Sep;55(9):2660-3.

48.

New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals.

Bochenski J, Placha G, Wanic K, Malecki M, Sieradzki J, Warram JH, Krolewski AS.

Diabetes. 2006 Sep;55(9):2626-30.

49.

Genetics of Kidneys in Diabetes (GoKinD) study: a genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes.

Mueller PW, Rogus JJ, Cleary PA, Zhao Y, Smiles AM, Steffes MW, Bucksa J, Gibson TB, Cordovado SK, Krolewski AS, Nierras CR, Warram JH.

J Am Soc Nephrol. 2006 Jul;17(7):1782-90. Epub 2006 Jun 14.

50.

A newly identified mutation in an IPF1 binding site of the insulin gene promoter may predispose to type 2 diabetes mellitus.

Malecki MT, Lebrun P, Pezzolesi M, Warram JH, Krolewski AS, Jhala US.

Diabetologia. 2006 Aug;49(8):1985-7. Epub 2006 Jun 2. No abstract available.

PMID:
16741735

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