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Items: 1 to 50 of 354

1.

Classic Papers Revisited: An Early Study of Cardioprotection by Volatile Anesthetics: A Behind-the-scenes Look.

Warltier DC.

Anesthesiology. 2018 Sep;129(3):576-579. doi: 10.1097/ALN.0000000000002305.

PMID:
29985198
2.

Failure of Isoflurane Cardiac Preconditioning in Obese Type 2 Diabetic Mice Involves Aberrant Regulation of MicroRNA-21, Endothelial Nitric-oxide Synthase, and Mitochondrial Complex I.

Ge ZD, Li Y, Qiao S, Bai X, Warltier DC, Kersten JR, Bosnjak ZJ, Liang M.

Anesthesiology. 2018 Jan;128(1):117-129. doi: 10.1097/ALN.0000000000001926.

3.

Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling.

Liu Y, Baumgardt SL, Fang J, Shi Y, Qiao S, Bosnjak ZJ, Vásquez-Vivar J, Xia Z, Warltier DC, Kersten JR, Ge ZD.

Sci Rep. 2017 Jun 8;7(1):3093. doi: 10.1038/s41598-017-03234-6.

4.

Cardiomyocyte GTP Cyclohydrolase 1 Protects the Heart Against Diabetic Cardiomyopathy.

Wu HE, Baumgardt SL, Fang J, Paterson M, Liu Y, Du J, Shi Y, Qiao S, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD.

Sci Rep. 2016 Jun 13;6:27925. doi: 10.1038/srep27925.

5.

Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice.

Baumgardt SL, Paterson M, Leucker TM, Fang J, Zhang DX, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD.

Circ Heart Fail. 2016 Jan;9(1):e002424. doi: 10.1161/CIRCHEARTFAILURE.115.002424.

6.

MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia-Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway.

Qiao S, Olson JM, Paterson M, Yan Y, Zaja I, Liu Y, Riess ML, Kersten JR, Liang M, Warltier DC, Bosnjak ZJ, Ge ZD.

Anesthesiology. 2015 Oct;123(4):786-798. doi: 10.1097/ALN.0000000000000807.

7.

Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats.

Baotic I, Weihrauch D, Procknow J, Vasquez-Vivar J, Ge ZD, Sudhakaran S, Warltier DC, Kersten JR.

Anesthesiology. 2015 Sep;123(3):582-9. doi: 10.1097/ALN.0000000000000778.

8.

Cardioprotection during diabetes: the role of mitochondrial DNA.

Muravyeva M, Baotic I, Bienengraeber M, Lazar J, Bosnjak ZJ, Sedlic F, Warltier DC, Kersten JR.

Anesthesiology. 2014 Apr;120(4):870-9. doi: 10.1097/ALN.0000000000000107.

9.

Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury.

Leucker TM, Ge ZD, Procknow J, Liu Y, Shi Y, Bienengraeber M, Warltier DC, Kersten JR.

PLoS One. 2013 Jul 22;8(7):e70088. doi: 10.1371/journal.pone.0070088. Print 2013.

10.

Far red/near infrared light treatment promotes femoral artery collateralization in the ischemic hindlimb.

Lohr NL, Ninomiya JT, Warltier DC, Weihrauch D.

J Mol Cell Cardiol. 2013 Sep;62:36-42. doi: 10.1016/j.yjmcc.2013.05.007. Epub 2013 May 20.

11.

Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia.

Baotic I, Ge ZD, Sedlic F, Coon A, Weihrauch D, Warltier DC, Kersten JR.

Am J Physiol Heart Circ Physiol. 2013 Jul 15;305(2):H219-27. doi: 10.1152/ajpheart.00850.2012. Epub 2013 May 10.

12.

Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning.

Vladic N, Ge ZD, Leucker T, Brzezinska AK, Du JH, Shi Y, Warltier DC, Pratt PF Jr, Kersten JR.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2130-9. doi: 10.1152/ajpheart.01078.2010. Epub 2011 Sep 9.

13.

Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning.

Hirata N, Shim YH, Pravdic D, Lohr NL, Pratt PF Jr, Weihrauch D, Kersten JR, Warltier DC, Bosnjak ZJ, Bienengraeber M.

Anesthesiology. 2011 Sep;115(3):531-40. doi: 10.1097/ALN.0b013e31822a2316.

14.

Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection.

Leucker TM, Bienengraeber M, Muravyeva M, Baotic I, Weihrauch D, Brzezinska AK, Warltier DC, Kersten JR, Pratt PF Jr.

J Mol Cell Cardiol. 2011 Nov;51(5):803-11. doi: 10.1016/j.yjmcc.2011.06.026. Epub 2011 Jul 21.

15.

Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia.

Ge ZD, Ionova IA, Vladic N, Pravdic D, Hirata N, Vásquez-Vivar J, Pratt PF Jr, Warltier DC, Pieper GM, Kersten JR.

Cardiovasc Res. 2011 Jul 15;91(2):340-9. doi: 10.1093/cvr/cvr079. Epub 2011 Mar 21.

16.

History of post-traumatic stress disorder is associated with impaired neuropsychometric performance after coronary artery surgery.

Hudetz JA, Gandhi SD, Iqbal Z, Patterson KM, Byrne AJ, Warltier DC, Pagel PS.

J Cardiothorac Vasc Anesth. 2010 Dec;24(6):964-8. doi: 10.1053/j.jvca.2010.02.019. Epub 2010 May 21.

PMID:
20494591
17.

Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion.

Pravdic D, Mio Y, Sedlic F, Pratt PF, Warltier DC, Bosnjak ZJ, Bienengraeber M.

Br J Pharmacol. 2010 May;160(2):220-32. doi: 10.1111/j.1476-5381.2010.00698.x.

18.

Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients.

Hudetz JA, Hoffmann RG, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS.

J Cardiothorac Vasc Anesth. 2010 Aug;24(4):560-7. doi: 10.1053/j.jvca.2010.01.004. Epub 2010 Mar 26.

PMID:
20346702
19.

Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms.

Amour J, Brzezinska AK, Jager Z, Sullivan C, Weihrauch D, Du J, Vladic N, Shi Y, Warltier DC, Pratt PF Jr, Kersten JR.

Anesthesiology. 2010 Mar;112(3):576-85. doi: 10.1097/ALN.0b013e3181cded1f.

20.

Postoperative delirium is associated with postoperative cognitive dysfunction at one week after cardiac surgery with cardiopulmonary bypass.

Hudetz JA, Patterson KM, Byrne AJ, Pagel PS, Warltier DC.

Psychol Rep. 2009 Dec;105(3 Pt 1):921-32.

PMID:
20099555
21.

A history of alcohol dependence increases the incidence and severity of postoperative cognitive dysfunction in cardiac surgical patients.

Hudetz JA, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS.

Int J Environ Res Public Health. 2009 Nov;6(11):2725-39. doi: 10.3390/ijerph6112725. Epub 2009 Oct 27.

22.

Isoflurane postconditioning protects against reperfusion injury by preventing mitochondrial permeability transition by an endothelial nitric oxide synthase-dependent mechanism.

Ge ZD, Pravdic D, Bienengraeber M, Pratt PF Jr, Auchampach JA, Gross GJ, Kersten JR, Warltier DC.

Anesthesiology. 2010 Jan;112(1):73-85. doi: 10.1097/ALN.0b013e3181c4a607.

23.

Myocardial interstitial fluid inhibits proliferation and cardiomyocyte differentiation in pluripotent embryonic stem cells.

Van Orman JR, Weihrauch D, Warltier DC, Lough J.

Am J Physiol Heart Circ Physiol. 2009 Oct;297(4):H1369-76. doi: 10.1152/ajpheart.00172.2009. Epub 2009 Jul 24.

24.

Ketamine attenuates post-operative cognitive dysfunction after cardiac surgery.

Hudetz JA, Iqbal Z, Gandhi SD, Patterson KM, Byrne AJ, Hudetz AG, Pagel PS, Warltier DC.

Acta Anaesthesiol Scand. 2009 Aug;53(7):864-72. doi: 10.1111/j.1399-6576.2009.01978.x. Epub 2009 Apr 28.

PMID:
19422355
25.

Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosyl myoglobin by red/near infrared radiation: potential role in cardioprotection.

Lohr NL, Keszler A, Pratt P, Bienengraber M, Warltier DC, Hogg N.

J Mol Cell Cardiol. 2009 Aug;47(2):256-63. doi: 10.1016/j.yjmcc.2009.03.009. Epub 2009 Mar 25.

26.

Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass.

Hudetz JA, Patterson KM, Iqbal Z, Gandhi SD, Byrne AJ, Hudetz AG, Warltier DC, Pagel PS.

J Cardiothorac Vasc Anesth. 2009 Oct;23(5):651-7. doi: 10.1053/j.jvca.2008.12.021. Epub 2009 Feb 23.

PMID:
19231245
27.

Morphine reduces the threshold of helium preconditioning against myocardial infarction: the role of opioid receptors in rabbits.

Pagel PS, Krolikowski JG, Amour J, Warltier DC, Weihrauch D.

J Cardiothorac Vasc Anesth. 2009 Oct;23(5):619-24. doi: 10.1053/j.jvca.2008.12.020. Epub 2009 Feb 23.

28.

Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning.

Amour J, Brzezinska AK, Weihrauch D, Billstrom AR, Zielonka J, Krolikowski JG, Bienengraeber MW, Warltier DC, Pratt PF Jr, Kersten JR.

Anesthesiology. 2009 Feb;110(2):317-25. doi: 10.1097/ALN.0b013e3181942cb4. Erratum in: Anesthesiology. 2009 Jun;110(6):1435.

29.

Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo.

Zhang DX, Mendoza SA, Bubolz AH, Mizuno A, Ge ZD, Li R, Warltier DC, Suzuki M, Gutterman DD.

Hypertension. 2009 Mar;53(3):532-8. doi: 10.1161/HYPERTENSIONAHA.108.127100. Epub 2009 Feb 2.

30.

Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism.

Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, Bienengraeber M.

J Mol Cell Cardiol. 2009 Jan;46(1):4-14. doi: 10.1016/j.yjmcc.2008.09.707. Epub 2008 Sep 30.

31.

Zeljko J. Bosnjak, Ph.D., recipient of the 2008 Excellence in Research Award.

Warltier DC.

Anesthesiology. 2008 Sep;109(3):371-3. No abstract available.

PMID:
18754138
32.

Inhibition of glycogen synthase kinase or the apoptotic protein p53 lowers the threshold of helium cardioprotection in vivo: the role of mitochondrial permeability transition.

Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D.

Anesth Analg. 2008 Sep;107(3):769-75. doi: 10.1213/ane.0b013e3181815b84.

33.

The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits.

Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D.

Anesth Analg. 2008 Sep;107(3):762-8. doi: 10.1213/ane.0b013e3181815995.

34.

Reactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo.

Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D.

J Cardiothorac Vasc Anesth. 2008 Aug;22(4):554-9. doi: 10.1053/j.jvca.2008.04.005. Epub 2008 Jun 17.

35.

Treatment of acute postoperative hypertension in cardiac surgery patients: an efficacy study of clevidipine assessing its postoperative antihypertensive effect in cardiac surgery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial.

Singla N, Warltier DC, Gandhi SD, Lumb PD, Sladen RN, Aronson S, Newman MF, Corwin HL; ESCAPE-2 Study Group.

Anesth Analg. 2008 Jul;107(1):59-67. doi: 10.1213/ane.0b013e3181732e53.

PMID:
18635468
36.

Simvastatin restores ischemic preconditioning in the presence of hyperglycemia through a nitric oxide-mediated mechanism.

Gu W, Kehl F, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR.

Anesthesiology. 2008 Apr;108(4):634-42. doi: 10.1097/ALN.0b013e3181672590.

37.

Cognitive function in older diabetic subjects with a history of alcohol abuse.

Hudetz JA, Warltier DC.

Psychol Rep. 2007 Dec;101(3 Pt 2):1125-32.

PMID:
18361128
38.

Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection.

Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR.

J Cardiovasc Pharmacol. 2007 Dec;50(6):670-6.

PMID:
18091584
39.

Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo.

Pagel PS, Krolikowski JG, Shim YH, Venkatapuram S, Kersten JR, Weihrauch D, Warltier DC, Pratt PF Jr.

Anesth Analg. 2007 Sep;105(3):562-9.

PMID:
17717207
40.

Volume replacement therapy during major orthopedic surgery using Voluven (hydroxyethyl starch 130/0.4) or hetastarch.

Gandhi SD, Weiskopf RB, Jungheinrich C, Koorn R, Miller D, Shangraw RE, Prough DS, Baus D, Bepperling F, Warltier DC.

Anesthesiology. 2007 Jun;106(6):1120-7.

PMID:
17525586
41.

Postoperative cognitive dysfunction in older patients with a history of alcohol abuse.

Hudetz JA, Iqbal Z, Gandhi SD, Patterson KM, Hyde TF, Reddy DM, Hudetz AG, Warltier DC.

Anesthesiology. 2007 Mar;106(3):423-30.

PMID:
17325499
42.

Isoflurane preconditioning uncouples mitochondria and protects against hypoxia-reoxygenation.

Ljubkovic M, Mio Y, Marinovic J, Stadnicka A, Warltier DC, Bosnjak ZJ, Bienengraeber M.

Am J Physiol Cell Physiol. 2007 May;292(5):C1583-90. Epub 2007 Jan 10.

43.

Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits.

Venkatapuram S, Wang C, Krolikowski JG, Weihrauch D, Kersten JR, Warltier DC, Pratt PF Jr, Pagel PS.

Anesth Analg. 2006 Dec;103(6):1400-5.

PMID:
17122210
44.

Ischemic preconditioning, myocardial stunning and anesthesia.

Toller WG, Kersten JR, Pagel PS, Warltier DC.

Curr Opin Anaesthesiol. 2000 Feb;13(1):35-40.

PMID:
17016277
45.

Nitrous oxide and preconditioning.

Pagel PS, Warltier DC.

Anesthesiology. 2006 Sep;105(3):630; author reply 631. No abstract available.

PMID:
16932006
46.

Mechanism of cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel activation by isoflurane in a heterologous expression system.

Bienengraeber M, Warltier DC, Bosnjak ZJ, Stadnicka A.

Anesthesiology. 2006 Sep;105(3):534-40.

PMID:
16931986
47.

Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats.

Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS.

Anesth Analg. 2006 Aug;103(2):281-8, table of contents.

PMID:
16861403
48.

Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase.

Wang C, Chiari PC, Weihrauch D, Krolikowski JG, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS.

Anesth Analg. 2006 Aug;103(2):274-80, table of contents.

PMID:
16861402
49.

Cardioprotection by volatile anesthetics: new applications for old drugs?

Pratt PF Jr, Wang C, Weihrauch D, Bienengraeber MW, Kersten JR, Pagel PS, Warltier DC.

Curr Opin Anaesthesiol. 2006 Aug;19(4):397-403. Review.

PMID:
16829721

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