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Items: 1 to 50 of 128

1.

The Highly Pure Neem Leaf Extract, SCNE, Inhibits Tumorigenesis in Oral Squamous Cell Carcinoma via Disruption of Pro-tumor Inflammatory Cytokines and Cell Signaling.

Morris J, Gonzales CB, De La Chapa JJ, Cabang AB, Fountzilas C, Patel M, Orozco S, Wargovich MJ.

Front Oncol. 2019 Sep 13;9:890. doi: 10.3389/fonc.2019.00890. eCollection 2019.

2.

Disruption of Epigenetic Silencing in Human Colon Cancer Cells Lines Utilizing a Novel Supercritical CO2 Extract of Neem Leaf (Azadirachta indica).

Qiu Z, Andrijauskaite K, Morris J, Wargovich MJ.

Anticancer Res. 2019 Oct;39(10):5473-5481. doi: 10.21873/anticanres.13740.

PMID:
31570441
3.

A supercritical CO2 extract of neem leaf (A. indica) and its bioactive liminoid, nimbolide, suppresses colon cancer in preclinical models by modulating pro-inflammatory pathways.

Patel MJ, Tripathy S, Mukhopadhyay KD, Wangjam T, Cabang AB, Morris J, Wargovich MJ.

Mol Carcinog. 2018 Sep;57(9):1156-1165. doi: 10.1002/mc.22832. Epub 2018 May 8.

PMID:
29697164
4.

Therapeutic effects of the euglenoid ichthyotoxin, euglenophycin, in colon cancer.

Cabang AB, De Mukhopadhyay K, Meyers S, Morris J, Zimba PV, Wargovich MJ.

Oncotarget. 2017 Nov 1;8(61):104347-104358. doi: 10.18632/oncotarget.22238. eCollection 2017 Nov 28.

5.

Reduction in promotor methylation utilizing EGCG (epigallocatechin-3-gallate) restores RXRα expression in human colon cancer cells.

Morris J, Moseley VR, Cabang AB, Coleman K, Wei W, Garrett-Mayer E, Wargovich MJ.

Oncotarget. 2016 Jun 7;7(23):35313-26. doi: 10.18632/oncotarget.9204.

6.

Natural Agents Used in Chemoprevention of Aerodigestive and GI Cancers.

Morris J, Fang Y, De Mukhopdhyay K, Wargovich MJ.

Curr Pharmacol Rep. 2016 Feb;2(1):11-20. Epub 2016 Jan 16.

7.

Chemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer.

Khoogar R, Kim BC, Morris J, Wargovich MJ.

Am J Physiol Gastrointest Liver Physiol. 2016 May 1;310(9):G629-44. doi: 10.1152/ajpgi.00201.2015. Epub 2016 Feb 18. Review.

8.
9.

Future directions in the prevention of prostate cancer.

Thompson IM Jr, Cabang AB, Wargovich MJ.

Nat Rev Clin Oncol. 2014 Jan;11(1):49-60. doi: 10.1038/nrclinonc.2013.211. Epub 2013 Nov 26. Review.

10.

Vitamin D receptor and retinoid X receptor α status and vitamin D insufficiency in models of murine colitis.

Knackstedt RW, Moseley VR, Sun S, Wargovich MJ.

Cancer Prev Res (Phila). 2013 Jun;6(6):585-93. doi: 10.1158/1940-6207.CAPR-12-0488. Epub 2013 Apr 12.

11.

Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage.

Luo H, Yang A, Schulte BA, Wargovich MJ, Wang GY.

PLoS One. 2013;8(3):e60065. doi: 10.1371/journal.pone.0060065. Epub 2013 Mar 22.

12.

Racial disparities in advanced-stage colorectal cancer survival.

Wallace K, Hill EG, Lewin DN, Williamson G, Oppenheimer S, Ford ME, Wargovich MJ, Berger FG, Bolick SW, Thomas MB, Alberg AJ.

Cancer Causes Control. 2013 Mar;24(3):463-71. doi: 10.1007/s10552-012-0133-5. Epub 2013 Jan 8.

13.

Epigenetic mechanisms underlying diet-sourced compounds in the prevention and treatment of gastrointestinal cancer.

Knackstedt RW, Moseley VR, Wargovich MJ.

Anticancer Agents Med Chem. 2012 Dec;12(10):1203-10.

14.

A limited role of p53 on the ability of a Hexane fraction of American ginseng to suppress mouse colitis.

Poudyal D, Cui X, Mai Le P, Davis T, Hofseth AB, Jin Y, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ.

J Biomed Biotechnol. 2012;2012:785739. doi: 10.1155/2012/785739. Epub 2012 Jul 30.

15.

Homeostatic imbalance and colon cancer: the dynamic epigenetic interplay of inflammation, environmental toxins, and chemopreventive plant compounds.

Sokolosky ML, Wargovich MJ.

Front Oncol. 2012 Jun 1;2:57. doi: 10.3389/fonc.2012.00057. eCollection 2012.

16.

A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms.

Poudyal D, Le PM, Davis T, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ.

Cancer Prev Res (Phila). 2012 Apr;5(4):685-96. doi: 10.1158/1940-6207.CAPR-11-0421. Epub 2012 Jan 31.

17.

Nutraceutical use in late-stage cancer.

Wargovich MJ, Morris J, Brown V, Ellis J, Logothetis B, Weber R.

Cancer Metastasis Rev. 2010 Sep;29(3):503-10. doi: 10.1007/s10555-010-9240-5. Review.

18.

Aberrant crypt foci: the case for inclusion as a biomarker for colon cancer.

Wargovich MJ, Brown VR, Morris J.

Cancers (Basel). 2010 Sep 16;2(3):1705-16. doi: 10.3390/cancers2031705.

19.

Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.

Volate SR, Muga SJ, Issa AY, Nitcheva D, Smith T, Wargovich MJ.

Mol Carcinog. 2009 Oct;48(10):920-33. doi: 10.1002/mc.20542.

20.

Khayanolides from African mahogany Khaya senegalensis (Meliaceae): A revision.

Zhang H, Tan J, Vanderveer D, Wang X, Wargovich MJ, Chen F.

Phytochemistry. 2009 Jan;70(2):294-9. doi: 10.1016/j.phytochem.2008.12.004. Epub 2009 Jan 10.

PMID:
19136128
21.

American ginseng suppresses inflammation and DNA damage associated with mouse colitis.

Jin Y, Kotakadi VS, Ying L, Hofseth AB, Cui X, Wood PA, Windust A, Matesic LE, Pena EA, Chiuzan C, Singh NP, Nagarkatti M, Nagarkatti PS, Wargovich MJ, Hofseth LJ.

Carcinogenesis. 2008 Dec;29(12):2351-9. doi: 10.1093/carcin/bgn211. Epub 2008 Sep 18.

22.

Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis.

Kotakadi VS, Jin Y, Hofseth AB, Ying L, Cui X, Volate S, Chumanevich A, Wood PA, Price RL, McNeal A, Singh UP, Singh NP, Nagarkatti M, Nagarkatti PS, Matesic LE, Auclair K, Wargovich MJ, Hofseth LJ.

Carcinogenesis. 2008 Sep;29(9):1799-806. doi: 10.1093/carcin/bgn143. Epub 2008 Jun 20.

23.

Effect of orlistat on fecal fat, fecal biliary acids, and colonic cell proliferation in obese subjects.

Ahnen DJ, Guerciolini R, Hauptman J, Blotner S, Woods CJ, Wargovich MJ.

Clin Gastroenterol Hepatol. 2007 Nov;5(11):1291-9. Epub 2007 Oct 24.

PMID:
17920338
24.

Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model.

Issa AY, Volate SR, Muga SJ, Nitcheva D, Smith T, Wargovich MJ.

Carcinogenesis. 2007 Sep;28(9):1978-84. Epub 2007 Jul 17.

PMID:
17638923
25.

Clinical validation of breast cancer biomarkers using tissue microarray technology.

Quraishi I, Rishi M, Feldman M, Wargovich MJ, Weber B.

Appl Immunohistochem Mol Morphol. 2007 Mar;15(1):45-9.

PMID:
17536306
26.

Anticancer activity of limonoid from Khaya senegalensis.

Zhang H, Wang X, Chen F, Androulakis XM, Wargovich MJ.

Phytother Res. 2007 Aug;21(8):731-4.

PMID:
17450502
27.

Colorectal cancer disparities in South Carolina: descriptive epidemiology, screening, special programs, and future direction.

Daguise VG, Burch JB, Horner MJ, Mosley C, Hofseth LJ, Wargovich MJ, Lloyd SC, Hebert JR.

J S C Med Assoc. 2006 Aug;102(7):212-20. Review. No abstract available.

PMID:
17319233
28.

Inflammation, cancer, and targets of ginseng.

Hofseth LJ, Wargovich MJ.

J Nutr. 2007 Jan;137(1 Suppl):183S-185S. doi: 10.1093/jn/137.1.183S. Review.

PMID:
17182823
29.

Nutrition and cancer: the herbal revolution.

Wargovich MJ.

Curr Opin Gastroenterol. 1999 Mar;15(2):177-80.

PMID:
17023941
30.

What do diet-induced alterations in colorectal polyps and aberrant crypts indicate for risk?

Wargovich MJ.

J Nutr. 2006 Oct;136(10):2679S-80S. No abstract available.

PMID:
16988147
31.

Chemopreventive effects of Khaya senegalensis bark extract on human colorectal cancer.

Androulakis XM, Muga SJ, Chen F, Koita Y, Toure B, Wargovich MJ.

Anticancer Res. 2006 May-Jun;26(3B):2397-405.

32.

Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis.

Peng G, Dixon DA, Muga SJ, Smith TJ, Wargovich MJ.

Mol Carcinog. 2006 May;45(5):309-19.

PMID:
16508969
33.

Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models.

Wargovich MJ.

J Nutr. 2006 Mar;136(3 Suppl):832S-834S. doi: 10.1093/jn/136.3.832S. Review.

PMID:
16484575
34.

Sphingosine kinase 1 is up-regulated in colon carcinogenesis.

Kawamori T, Osta W, Johnson KR, Pettus BJ, Bielawski J, Tanaka T, Wargovich MJ, Reddy BS, Hannun YA, Obeid LM, Zhou D.

FASEB J. 2006 Feb;20(2):386-8. Epub 2005 Nov 30.

PMID:
16319132
35.

Anti-proliferative effects of green tea polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial cells.

Peng G, Wargovich MJ, Dixon DA.

Cancer Lett. 2006 Jul 18;238(2):260-70. Epub 2005 Sep 12.

PMID:
16157446
36.

Novel genetic variations of the p53R2 gene in patients with colorectal adenoma and controls.

Deng ZL, Xie DW, Bostick RM, Miao XJ, Gong YL, Zhang JH, Wargovich MJ.

World J Gastroenterol. 2005 Sep 7;11(33):5169-73.

37.

Histamine receptor antagonists and incident colorectal adenomas.

Robertson DJ, Burke CA, Schwender BJ, Wargovich MJ, Greenberg ER, Sandler RS, Ahnen DJ, Rothstein R, Mott LA, Baron JA.

Aliment Pharmacol Ther. 2005 Jul 15;22(2):123-8.

38.

Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic.

Davenport DM, Wargovich MJ.

Food Chem Toxicol. 2005 Dec;43(12):1753-62.

PMID:
16000231
39.

Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).

Volate SR, Davenport DM, Muga SJ, Wargovich MJ.

Carcinogenesis. 2005 Aug;26(8):1450-6. Epub 2005 Apr 14.

PMID:
15831530
40.

Methodologic considerations in the study of diet as part of complementary and alternative medicine modalities.

Zander ME, Wargovich MJ, Hebert JR.

Altern Ther Health Med. 2004 Nov-Dec;10(6):56-61. Review.

PMID:
15624350
41.

Expression of cellular adhesion proteins and abnormal glycoproteins in human aberrant crypt foci.

Wargovich MJ, Chang P, Velasco M, Sinicrope F, Eisenbrodt E, Sellin J.

Appl Immunohistochem Mol Morphol. 2004 Dec;12(4):350-5.

PMID:
15536336
42.

Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci.

Kim KP, Whitehead C, Piazza G, Wargovich MJ.

Anticancer Res. 2004 May-Jun;24(3a):1805-11.

43.

Polymorphism of the cyclin D1 gene, CCND1, and risk for incident sporadic colorectal adenomas.

Lewis RC, Bostick RM, Xie D, Deng Z, Wargovich MJ, Fina MF, Roufail WM, Geisinger KR.

Cancer Res. 2003 Dec 1;63(23):8549-53.

44.

The role of dietary supplements during cancer therapy.

Norman HA, Butrum RR, Feldman E, Heber D, Nixon D, Picciano MF, Rivlin R, Simopoulos A, Wargovich MJ, Weisburger EK, Zeisel SH.

J Nutr. 2003 Nov;133(11 Suppl 1):3794S-3799S. doi: 10.1093/jn/133.11.3794S. Review.

PMID:
14608116
45.

Opportunities and challenges for future nutrition research in cancer prevention: a panel discussion.

Milner JA, Allison RG, Elliott JG, Go VL, Miller GA, Rock C, Roy R, Wargovich MJ.

J Nutr. 2003 Jul;133(7 Suppl):2502S-2504S. doi: 10.1093/jn/133.7.2502S. No abstract available.

PMID:
12840231
46.

Diet, individual responsiveness and cancer prevention.

Wargovich MJ, Cunningham JE.

J Nutr. 2003 Jul;133(7 Suppl):2400S-2403S. doi: 10.1093/jn/133.7.2400S. Review.

PMID:
12840215
47.

Post-study aspirin intake and factors motivating participation in a colorectal cancer chemoprevention trial.

Sample DA, Sinicrope PS, Wargovich MJ, Sinicrope FA.

Cancer Epidemiol Biomarkers Prev. 2002 Mar;11(3):281-5.

48.

Colon cancer chemoprevention with ginseng and other botanicals.

Wargovich MJ.

J Korean Med Sci. 2001 Dec;16 Suppl:S81-6. Review.

49.

Herbals, cancer prevention and health.

Wargovich MJ, Woods C, Hollis DM, Zander ME.

J Nutr. 2001 Nov;131(11 Suppl):3034S-6S. doi: 10.1093/jn/131.11.3034S. Review.

PMID:
11694643
50.

Herbals and cancer.

Wargovich MJ.

Adv Exp Med Biol. 2001;492:195-202. Review. No abstract available.

PMID:
11480667

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