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Items: 18


Activation of Bvg-Repressed Genes in Bordetella pertussis by RisA Requires Cross Talk from Noncooperonic Histidine Kinase RisK.

Chen Q, Ng V, Warfel JM, Merkel TJ, Stibitz S.

J Bacteriol. 2017 Oct 17;199(22). pii: e00475-17. doi: 10.1128/JB.00475-17. Print 2017 Nov 15.


Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with Bordetella pertussis.

Eby JC, Gray MC, Warfel JM, Merkel TJ, Hewlett EL.

Clin Vaccine Immunol. 2017 Jan 5;24(1). pii: e00370-16. doi: 10.1128/CVI.00370-16. Print 2017 Jan.


Comparison of Three Whole-Cell Pertussis Vaccines in the Baboon Model of Pertussis.

Warfel JM, Zimmerman LI, Merkel TJ.

Clin Vaccine Immunol. 2015 Nov 11;23(1):47-54. doi: 10.1128/CVI.00449-15. Print 2016 Jan.


Pertussis vaccines and the challenge of inducing durable immunity.

Warfel JM, Edwards KM.

Curr Opin Immunol. 2015 Aug;35:48-54. doi: 10.1016/j.coi.2015.05.008. Epub 2015 Jun 17. Review.


The baboon model of pertussis: effective use and lessons for pertussis vaccines.

Warfel JM, Merkel TJ.

Expert Rev Vaccines. 2014 Oct;13(10):1241-52. doi: 10.1586/14760584.2014.946016. Epub 2014 Sep 3. Review.


Reply to Domenech de Cell├Ęs et al.: Infection and transmission of pertussis in the baboon model.

Warfel JM, Merkel TJ.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):E718. No abstract available.


Maternal and neonatal vaccination protects newborn baboons from pertussis infection.

Warfel JM, Papin JF, Wolf RF, Zimmerman LI, Merkel TJ.

J Infect Dis. 2014 Aug 15;210(4):604-10. doi: 10.1093/infdis/jiu090. Epub 2014 Feb 12.


Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model.

Warfel JM, Zimmerman LI, Merkel TJ.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):787-92. doi: 10.1073/pnas.1314688110. Epub 2013 Nov 25.


Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions.

D'Agnillo F, Williams MC, Moayeri M, Warfel JM.

PLoS One. 2013 Apr 23;8(4):e62576. doi: 10.1371/journal.pone.0062576. Print 2013.


Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection.

Eby JC, Gray MC, Warfel JM, Paddock CD, Jones TF, Day SR, Bowden J, Poulter MD, Donato GM, Merkel TJ, Hewlett EL.

Infect Immun. 2013 May;81(5):1390-8. doi: 10.1128/IAI.00110-13. Epub 2013 Feb 19.


Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates.

Warfel JM, Merkel TJ.

Mucosal Immunol. 2013 Jul;6(4):787-96. doi: 10.1038/mi.2012.117. Epub 2012 Nov 28.


Airborne transmission of Bordetella pertussis.

Warfel JM, Beren J, Merkel TJ.

J Infect Dis. 2012 Sep 15;206(6):902-6. doi: 10.1093/infdis/jis443. Epub 2012 Jul 17.


Nonhuman primate model of pertussis.

Warfel JM, Beren J, Kelly VK, Lee G, Merkel TJ.

Infect Immun. 2012 Apr;80(4):1530-6. doi: 10.1128/IAI.06310-11. Epub 2012 Jan 17.


Anthrax lethal toxin-mediated disruption of endothelial VE-cadherin is attenuated by inhibition of the Rho-associated kinase pathway.

Warfel JM, D'Agnillo F.

Toxins (Basel). 2011 Oct;3(10):1278-93. doi: 10.3390/toxins3101278. Epub 2011 Oct 20.


Anthrax lethal toxin enhances IkappaB kinase activation and differentially regulates pro-inflammatory genes in human endothelium.

Warfel JM, D'Agnillo F.

J Biol Chem. 2009 Sep 18;284(38):25761-71. doi: 10.1074/jbc.M109.036970. Epub 2009 Jul 20.


Anthrax lethal toxin enhances cytokine-induced VCAM-1 expression on human endothelial cells.

Steele AD, Warfel JM, D'Agnillo F.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1249-56. Epub 2005 Oct 7.


Anthrax lethal toxin induces endothelial barrier dysfunction.

Warfel JM, Steele AD, D'Agnillo F.

Am J Pathol. 2005 Jun;166(6):1871-81.

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