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Items: 1 to 50 of 94


Extended-spectrum β-lactamase-producing Escherichia coli in human-derived and foodchain-derived samples from England, Wales, and Scotland: an epidemiological surveillance and typing study.

Day MJ, Hopkins KL, Wareham DW, Toleman MA, Elviss N, Randall L, Teale C, Cleary P, Wiuff C, Doumith M, Ellington MJ, Woodford N, Livermore DM.

Lancet Infect Dis. 2019 Oct 22. pii: S1473-3099(19)30273-7. doi: 10.1016/S1473-3099(19)30273-7. [Epub ahead of print]


Cefepime/sulbactam as an enhanced antimicrobial combination therapy for the treatment of MDR Gram-negative infections.

Wareham DW, Momin MHFA, Phee LM, Hornsey M, Standing JF.

J Antimicrob Chemother. 2019 Oct 16. pii: dkz420. doi: 10.1093/jac/dkz420. [Epub ahead of print]


A novel plasmid-mediated polymyxin resistance determinant (mcr-1.8) in Escherichia coli recovered from broiler chickens in Brunei Darussalam.

Abdul Momin MHF, Liakopoulos A, Bean DC, Phee LM, Wareham DW.

J Antimicrob Chemother. 2019 Nov 1;74(11):3392-3394. doi: 10.1093/jac/dkz352. No abstract available.


Hypermucoviscous polymyxin-resistant Klebsiella pneumoniae from Kolkata, India: Genomic and phenotypic analysis.

Bean DC, Agarwal A, Cherian BP, Wareham DW.

J Glob Antimicrob Resist. 2019 Jun;17:1-2. doi: 10.1016/j.jgar.2019.02.012. Epub 2019 Feb 27.


Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii.

Phee LM, Kloprogge F, Morris R, Barrett J, Wareham DW, Standing JF.

J Antimicrob Chemother. 2019 Apr 1;74(4):961-969. doi: 10.1093/jac/dky524.


Characterization of a colistin-resistant Avian Pathogenic Escherichia coli ST69 isolate recovered from a broiler chicken in Germany.

Hornsey M, Betts JW, Mehat JW, Wareham DW, van Vliet AHM, Woodward MJ, La Ragione RM.

J Med Microbiol. 2019 Jan;68(1):111-114. doi: 10.1099/jmm.0.000882. Epub 2018 Nov 26.


OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli.

Livermore DM, Day M, Cleary P, Hopkins KL, Toleman MA, Wareham DW, Wiuff C, Doumith M, Woodford N.

J Antimicrob Chemother. 2019 Feb 1;74(2):326-333. doi: 10.1093/jac/dky453.


Direct detection of carbapenem resistance determinants in clinical specimens using immunochromatographic lateral flow devices.

Wareham DW, Phee LM, Abdul Momin MHF.

J Antimicrob Chemother. 2018 Jul 1;73(7):1997-1998. doi: 10.1093/jac/dky095. No abstract available.


Effects of In vivo Emergent Tigecycline Resistance on the Pathogenic Potential of Acinetobacter baumannii.

Hornsey M, Wareham DW.

Sci Rep. 2018 Mar 9;8(1):4234. doi: 10.1038/s41598-018-22549-6.


Prevalence of carbapenem resistance and carbapenemase production among Enterobacteriaceae isolated from urine in the UK: results of the UK infection-Carbapenem Resistance Evaluation Surveillance Trial (iCREST-UK).

Woodford N, Xu-McCrae L, Mushtaq S, Wu HHT, Ellington MJ, Lancaster O, Davies F, Donaldson H, Rao GG, Verma A, Wareham DW, Ciesielczuk H, Stone GG, Irani PM, Bracher S, Hawkey PM.

J Antimicrob Chemother. 2018 Mar 1;73(3):698-702. doi: 10.1093/jac/dkx471.


Optimal detection of carbapenemase-producing Enterobacteriaceae from rectal samples: a role for enrichment?

Ciesielczuk H, Phee LM, Dolphin H, Wilks M, Cherian BP, Wareham DW.

J Hosp Infect. 2018 Mar;98(3):270-274. doi: 10.1016/j.jhin.2017.10.012. Epub 2017 Oct 23.


CHROMagar COL-APSE: a selective bacterial culture medium for the isolation and differentiation of colistin-resistant Gram-negative pathogens.

Abdul Momin MHF, Bean DC, Hendriksen RS, Haenni M, Phee LM, Wareham DW.

J Med Microbiol. 2017 Nov;66(11):1554-1561. doi: 10.1099/jmm.0.000602. Epub 2017 Oct 6.


Draft Genome Sequence of a Multidrug-Resistant Sequence Type 231 Outbreak-Associated Clone of Klebsiella pneumoniae, KP41-2015, Producing OXA-232 Carbapenemase.

Abdul Momin MHF, Liakopoulos A, Wareham DW.

Genome Announc. 2017 Jul 6;5(27). pii: e00604-17. doi: 10.1128/genomeA.00604-17.


In vitro and In vivo Activity of Theaflavin-Epicatechin Combinations versus Multidrug-Resistant Acinetobacter baumannii.

Betts JW, Hornsey M, Wareham DW, La Ragione RM.

Infect Dis Ther. 2017 Sep;6(3):435-442. doi: 10.1007/s40121-017-0161-2. Epub 2017 Jun 21.


Emergence and nosocomial spread of carbapenem-resistant OXA-232-producing Klebsiella pneumoniae in Brunei Darussalam.

Abdul Momin MHF, Liakopoulos A, Phee LM, Wareham DW.

J Glob Antimicrob Resist. 2017 Jun;9:96-99. doi: 10.1016/j.jgar.2017.02.008. Epub 2017 Apr 27.


NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors.

Li GB, Abboud MI, Brem J, Someya H, Lohans CT, Yang SY, Spencer J, Wareham DW, McDonough MA, Schofield CJ.

Chem Sci. 2017 Feb 1;8(2):928-937. doi: 10.1039/c6sc04524c. Epub 2016 Dec 14.


The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections.

Tängdén T, Ramos Martín V, Felton TW, Nielsen EI, Marchand S, Brüggemann RJ, Bulitta JB, Bassetti M, Theuretzbacher U, Tsuji BT, Wareham DW, Friberg LE, De Waele JJ, Tam VH, Roberts JA; Infection Section for the European Society of Intensive Care Medicine, the Pharmacokinetics and Pharmacodynamics Study Group of the European Society of Clinical Microbiology and Infectious Diseases, the International Society of Anti-Infective Pharmacology and the Critically Ill Patients Study Group of European Society of Clinical Microbiology and Infectious Diseases.

Intensive Care Med. 2017 Jul;43(7):1021-1032. doi: 10.1007/s00134-017-4780-6. Epub 2017 Apr 13. Review.


Draft Genome Sequence of a Canine Isolate of Methicillin-Resistant Staphylococcus haemolyticus.

Bean DC, Wigmore SM, Wareham DW.

Genome Announc. 2017 Apr 6;5(14). pii: e00146-17. doi: 10.1128/genomeA.00146-17.


Draft Genome Sequence of Providencia stuartii PS71, a Multidrug-Resistant Strain Associated with Nosocomial Infections in Greece.

Liakopoulos A, Oikonomou O, Wareham DW.

Genome Announc. 2017 Mar 23;5(12). pii: e00056-17. doi: 10.1128/genomeA.00056-17.


Draft Genome Sequence of Staphylococcus cohnii subsp. urealyticus Isolated from a Healthy Dog.

Bean DC, Wigmore SM, Wareham DW.

Genome Announc. 2017 Feb 16;5(7). pii: e01628-16. doi: 10.1128/genomeA.01628-16.


Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay.

Wareham DW, Abdul Momin MH.

J Clin Microbiol. 2017 Apr;55(4):1223-1225. doi: 10.1128/JCM.02471-16. Epub 2017 Feb 1. No abstract available.


Cyclic Boronates Inhibit All Classes of β-Lactamases.

Cahill ST, Cain R, Wang DY, Lohans CT, Wareham DW, Oswin HP, Mohammed J, Spencer J, Fishwick CW, McDonough MA, Schofield CJ, Brem J.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02260-16. doi: 10.1128/AAC.02260-16. Print 2017 Apr.


Rifaximin combined with polymyxins: A potential regimen for selective decontamination of multidrug-resistant bacteria in the digestive tract?

Betts JW, Phee LM, Wareham DW.

J Glob Antimicrob Resist. 2016 Mar;4:11-15. doi: 10.1016/j.jgar.2015.11.008. Epub 2015 Dec 23.


Providencia stuartii Isolates from Greece: Co-Carriage of Cephalosporin (blaSHV-5, blaVEB-1), Carbapenem (blaVIM-1), and Aminoglycoside (rmtB) Resistance Determinants by a Multidrug-Resistant Outbreak Clone.

Oikonomou O, Liakopoulos A, Phee LM, Betts J, Mevius D, Wareham DW.

Microb Drug Resist. 2016 Jul;22(5):379-86. doi: 10.1089/mdr.2015.0215. Epub 2016 Jan 26.


Trends in ExPEC serogroups in the UK and their significance.

Ciesielczuk H, Jenkins C, Chattaway M, Doumith M, Hope R, Woodford N, Wareham DW.

Eur J Clin Microbiol Infect Dis. 2016 Oct;35(10):1661-6. doi: 10.1007/s10096-016-2707-8. Epub 2016 Jun 22.


In Vitro Antibacterial Activity of Curcumin-Polymyxin B Combinations against Multidrug-Resistant Bacteria Associated with Traumatic Wound Infections.

Betts JW, Sharili AS, La Ragione RM, Wareham DW.

J Nat Prod. 2016 Jun 24;79(6):1702-6. doi: 10.1021/acs.jnatprod.6b00286. Epub 2016 Jun 13.


Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii.

Martínez-Guitián M, Vázquez-Ucha JC, Odingo J, Parish T, Poza M, Waite RD, Bou G, Wareham DW, Beceiro A.

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4375-9. doi: 10.1128/AAC.00510-16. Print 2016 Jul.


ESBL-producing Enterobacteriaceae in 24 neonatal units and associated networks in the south of England: no clustering of ESBL-producing Escherichia coli in units or networks.

Millar MR, Seale J, Turton J, Wilks M, Costeloe K, Woodford N, Juszczak E, Whiley A, Panton N, Wareham DW.

J Antimicrob Chemother. 2016 May;71(5):1174-7. doi: 10.1093/jac/dkv459. Epub 2016 Jan 10.


Evaluation of an Immunochromatographic Lateral Flow Assay (OXA-48 K-SeT) for Rapid Detection of OXA-48-Like Carbapenemases in Enterobacteriaceae.

Wareham DW, Shah R, Betts JW, Phee LM, Momin MH.

J Clin Microbiol. 2016 Feb;54(2):471-3. doi: 10.1128/JCM.02900-15. Epub 2015 Nov 25.


Characterization of the extra-intestinal pathogenic Escherichia coli ST131 clone among isolates recovered from urinary and bloodstream infections in the United Kingdom.

Ciesielczuk H, Doumith M, Hope R, Woodford N, Wareham DW.

J Med Microbiol. 2015 Dec;64(12):1496-503. doi: 10.1099/jmm.0.000179. Epub 2015 Oct 6.


In Vitro Activity of Epigallocatechin Gallate and Quercetin Alone and in Combination versus Clinical Isolates of Methicillin-Resistant Staphylococcus aureus.

Betts JW, Sharili AS, Phee LM, Wareham DW.

J Nat Prod. 2015 Aug 28;78(8):2145-8. doi: 10.1021/acs.jnatprod.5b00471. Epub 2015 Aug 12.


Colistin and Fusidic Acid, a Novel Potent Synergistic Combination for Treatment of Multidrug-Resistant Acinetobacter baumannii Infections.

Phee LM, Betts JW, Bharathan B, Wareham DW.

Antimicrob Agents Chemother. 2015 Aug;59(8):4544-50. doi: 10.1128/AAC.00753-15. Epub 2015 May 18.


Comparative virulence of urinary and bloodstream isolates of extra-intestinal pathogenic Escherichia coli in a Galleria mellonella model.

Ciesielczuk H, Betts J, Phee L, Doumith M, Hope R, Woodford N, Wareham DW.

Virulence. 2015;6(2):145-51. doi: 10.4161/21505594.2014.988095.


Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability.

Makena A, Brem J, Pfeffer I, Geffen RE, Wilkins SE, Tarhonskaya H, Flashman E, Phee LM, Wareham DW, Schofield CJ.

J Antimicrob Chemother. 2015 Feb;70(2):463-9. doi: 10.1093/jac/dku403. Epub 2014 Oct 16.


Activity of the type I signal peptidase inhibitor MD3 against multidrug-resistant Gram-negative bacteria alone and in combination with colistin.

Personne Y, Curtis MA, Wareham DW, Waite RD.

J Antimicrob Chemother. 2014 Dec;69(12):3236-43. doi: 10.1093/jac/dku309. Epub 2014 Aug 18.


Activity of colistin in combination with tigecycline or rifampicin against multidrug-resistant Stenotrophomonas maltophilia.

Betts JW, Phee LM, Woodford N, Wareham DW.

Eur J Clin Microbiol Infect Dis. 2014 Sep;33(9):1565-72. doi: 10.1007/s10096-014-2101-3. Epub 2014 Apr 30.


In vitro and in vivo activities of tigecycline-colistin combination therapies against carbapenem-resistant Enterobacteriaceae.

Betts JW, Phee LM, Hornsey M, Woodford N, Wareham DW.

Antimicrob Agents Chemother. 2014 Jun;58(6):3541-6. doi: 10.1128/AAC.02449-14. Epub 2014 Mar 31.


Carbapenemase-producing Enterobacteriaceae and non-Enterobacteriaceae from animals and the environment: an emerging public health risk of our own making?

Woodford N, Wareham DW, Guerra B, Teale C.

J Antimicrob Chemother. 2014 Feb;69(2):287-91. doi: 10.1093/jac/dkt392. Epub 2013 Oct 3. Review.


Development and evaluation of a multiplex PCR for eight plasmid-mediated quinolone-resistance determinants.

Ciesielczuk H, Hornsey M, Choi V, Woodford N, Wareham DW.

J Med Microbiol. 2013 Dec;62(Pt 12):1823-7. doi: 10.1099/jmm.0.064428-0. Epub 2013 Sep 2.


In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens.

Hornsey M, Phee L, Stubbings W, Wareham DW.

Int J Antimicrob Agents. 2013 Oct;42(4):343-6. doi: 10.1016/j.ijantimicag.2013.05.010. Epub 2013 Jul 7.


Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans.

Betts JW, Wareham DW, Haswell SJ, Kelly SM.

J Microbiol Biotechnol. 2013 Sep 28;23(9):1322-6.


In vitro activity of daptomycin in combination with low-dose colistin against a diverse collection of Gram-negative bacterial pathogens.

Phee L, Hornsey M, Wareham DW.

Eur J Clin Microbiol Infect Dis. 2013 Oct;32(10):1291-4. doi: 10.1007/s10096-013-1875-z. Epub 2013 Apr 23.


In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection.

Hornsey M, Phee L, Longshaw C, Wareham DW.

Int J Antimicrob Agents. 2013 Mar;41(3):285-7. doi: 10.1016/j.ijantimicag.2012.11.013. Epub 2013 Jan 9.


Evaluation of three selective chromogenic media, CHROMagar ESBL, CHROMagar CTX-M and CHROMagar KPC, for the detection of Klebsiella pneumoniae producing OXA-48 carbapenemase.

Hornsey M, Phee L, Woodford N, Turton J, Meunier D, Thomas C, Wareham DW.

J Clin Pathol. 2013 Apr;66(4):348-50. doi: 10.1136/jclinpath-2012-201234. Epub 2013 Jan 2.


Association of extended-spectrum β-lactamase VEB-5 and 16S rRNA methyltransferase armA in Salmonella enterica from the United Kingdom.

Hidalgo L, Hopkins KL, Wareham DW, Gutierrez B, González-Zorn B.

Antimicrob Agents Chemother. 2012 Sep;56(9):4985-7. doi: 10.1128/AAC.00381-12. Epub 2012 Jun 18. No abstract available.


In vitro activity of telavancin in combination with colistin versus Gram-negative bacterial pathogens.

Hornsey M, Longshaw C, Phee L, Wareham DW.

Antimicrob Agents Chemother. 2012 Jun;56(6):3080-5. doi: 10.1128/AAC.05870-11. Epub 2012 Apr 9.


A simple, semiselective medium for anaerobic isolation of anginosus group streptococci from patients with chronic lung disease.

Waite RD, Wareham DW, Gardiner S, Whiley RA.

J Clin Microbiol. 2012 Apr;50(4):1430-2. doi: 10.1128/JCM.06184-11. Epub 2012 Jan 11.


A novel variant, NDM-5, of the New Delhi metallo-β-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom.

Hornsey M, Phee L, Wareham DW.

Antimicrob Agents Chemother. 2011 Dec;55(12):5952-4. doi: 10.1128/AAC.05108-11. Epub 2011 Sep 19.

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