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Items: 1 to 50 of 284

1.

The ex vivo human lung: research value for translational science.

Ross JT, Nesseler N, Lee JW, Ware LB, Matthay MA.

JCI Insight. 2019 Jun 6;4(11). pii: 128833. doi: 10.1172/jci.insight.128833. eCollection 2019 Jun 6. Review.

2.

Pathogenesis of Acute Respiratory Distress Syndrome.

Huppert LA, Matthay MA, Ware LB.

Semin Respir Crit Care Med. 2019 Feb;40(1):31-39. doi: 10.1055/s-0039-1683996. Epub 2019 May 6.

PMID:
31060086
3.

Postreperfusion plasma endothelial activation markers are associated with acute kidney injury after lung transplantation.

Forker CM, Miano TA, Reilly JP, Oyster ML, Porteous MK, Cantu EE 3rd, Ware LB, Diamond JM, Christie JD, Shashaty MGS.

Am J Transplant. 2019 Apr 24. doi: 10.1111/ajt.15402. [Epub ahead of print]

PMID:
31017370
4.

Bronchoalveolar fluid and plasma inflammatory biomarkers in contemporary ARDS patients.

Stapleton RD, Suratt BT, Neff MJ, Wurfel MM, Ware LB, Ruzinski JT, Caldwell E, Hallstrand TS, Parsons PE.

Biomarkers. 2019 Jun;24(4):352-359. doi: 10.1080/1354750X.2019.1581840. Epub 2019 Mar 4.

PMID:
30744430
5.

Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury.

Yu WK, McNeil JB, Wickersham NE, Shaver CM, Bastarache JA, Ware LB.

Crit Care. 2019 Jan 18;23(1):18. doi: 10.1186/s13054-019-2315-y.

6.

Author Correction: Assembly of a pan-genome from deep sequencing of 910 humans of African descent.

Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware LB, Olopade CO, Olopade O, Oliveira RR, Ober C, Nicolae DL, Meyers DA, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker ER, Araujo MI, Herrera-Paz EF, Campbell M, Foster C, Taub MA, Beaty TH, Ruczinski I, Mathias RA, Barnes KC, Salzberg SL.

Nat Genet. 2019 Feb;51(2):364. doi: 10.1038/s41588-018-0335-1.

PMID:
30647471
7.

Assembly of a pan-genome from deep sequencing of 910 humans of African descent.

Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware LB, Olopade CO, Olopade O, Oliveira RR, Ober C, Nicolae DL, Meyers DA, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker ER, Araujo MI, Herrera-Paz EF, Campbell M, Foster C, Taub MA, Beaty TH, Ruczinski I, Mathias RA, Barnes KC, Salzberg SL.

Nat Genet. 2019 Jan;51(1):30-35. doi: 10.1038/s41588-018-0273-y. Epub 2018 Nov 19. Erratum in: Nat Genet. 2019 Feb;51(2):364.

8.

The Continued Need for Clinical Trials in Deceased Organ Donor Management.

Niemann CU, Matthay MA, Ware LB.

Transplantation. 2018 Nov 5. doi: 10.1097/TP.0000000000002512. [Epub ahead of print] No abstract available.

PMID:
30399123
9.

National Heart, Lung, and Blood Institute and American Association for Thoracic Surgery Workshop Report: Identifying collaborative clinical research priorities in lung transplantation.

Mulligan MS, Weill D, Davis RD, Christie JD, Farjah F, Singer JP, Hartwig M, Sanchez PG, Kreisel D, Ware LB, Bermudez C, Hachem RR, Weyant MJ, Gries C, Awori Hayanga JW, Griffith BP, Snyder LD, Odim J, Craig JM, Aggarwal NR, Reineck LA.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2355-2365. doi: 10.1016/j.jtcvs.2018.08.010. Epub 2018 Aug 18. No abstract available.

PMID:
30244865
10.

Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma.

Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB.

Am J Respir Crit Care Med. 2019 Jan 1;199(1):62-70. doi: 10.1164/rccm.201803-0435OC.

PMID:
30067389
11.

MUC5B Promoter Polymorphism and Development of Acute Respiratory Distress Syndrome.

Rogers AJ, Solus JF, Hunninghake GM, Baron RM, Meyer NJ, Janz DR, Schwartz DA, May AK, Lawson WE, Blackwell TS, Ware LB.

Am J Respir Crit Care Med. 2018 Nov 15;198(10):1342-1345. doi: 10.1164/rccm.201801-0140LE. No abstract available.

PMID:
30025215
12.

Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS.

Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, Rice TW, Matthay MA, Calfee CS, Ware LB.

Thorax. 2018 Sep;73(9):840-846. doi: 10.1136/thoraxjnl-2017-211280. Epub 2018 Jun 14.

PMID:
29903755
13.

Association Between Early Postoperative Acetaminophen Exposure and Acute Kidney Injury in Pediatric Patients Undergoing Cardiac Surgery.

Van Driest SL, Jooste EH, Shi Y, Choi L, Darghosian L, Hill KD, Smith AH, Kannankeril PJ, Roden DM, Ware LB.

JAMA Pediatr. 2018 Jul 1;172(7):655-663. doi: 10.1001/jamapediatrics.2018.0614.

14.

Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries.

Ware LB, Zhao Z, Koyama T, Brown RM, Semler MW, Janz DR, May AK, Fremont RD, Matthay MA, Cohen MJ, Calfee CS.

Trauma Surg Acute Care Open. 2017 Aug 28;2(1):e000121. doi: 10.1136/tsaco-2017-000121. eCollection 2017.

15.

Selective tumour necrosis factor receptor-1 inhibition in acute lung injury: a new hope or a false dawn?

Sinha P, Ware LB.

Thorax. 2018 Aug;73(8):699-701. doi: 10.1136/thoraxjnl-2017-211443. Epub 2018 Mar 22. No abstract available.

PMID:
29567751
16.

Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability.

Hughes CG, Patel MB, Brummel NE, Thompson JL, McNeil JB, Pandharipande PP, Jackson JC, Chandrasekhar R, Ware LB, Ely EW, Girard TD.

Intensive Care Med. 2018 Mar;44(3):345-355. doi: 10.1007/s00134-018-5120-1. Epub 2018 Mar 9.

17.

Fibroblast Growth Factor 23 Associates with Death in Critically Ill Patients.

Leaf DE, Siew ED, Eisenga MF, Singh K, Mc Causland FR, Srivastava A, Ikizler TA, Ware LB, Ginde AA, Kellum JA, Palevsky PM, Wolf M, Waikar SS.

Clin J Am Soc Nephrol. 2018 Apr 6;13(4):531-541. doi: 10.2215/CJN.10810917. Epub 2018 Mar 8.

18.

Stability of ARDS subphenotypes over time in two randomised controlled trials.

Delucchi K, Famous KR, Ware LB, Parsons PE, Thompson BT, Calfee CS; ARDS Network.

Thorax. 2018 May;73(5):439-445. doi: 10.1136/thoraxjnl-2017-211090. Epub 2018 Feb 24.

19.

Pediatric Acute Respiratory Distress Syndrome: Increase the Positive End-Expiratory Pressure?

McKown AC, Ware LB.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):7-9. doi: 10.1164/rccm.201802-0266ED. No abstract available.

PMID:
29451804
20.

Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis.

Annane D, Mira JP, Ware LB, Gordon AC, Hinds CJ, Christiani DC, Sevransky J, Barnes K, Buchman TG, Heagerty PJ, Balshaw R, Lesnikova N, de Nobrega K, Wellman HF, Neira M, Mancini ADJ, Walley KR, Russell JA.

Ann Intensive Care. 2018 Jan 31;8(1):16. doi: 10.1186/s13613-018-0353-2.

21.

Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.

Shaver CM, Wickersham N, McNeil JB, Nagata H, Miller A, Landstreet SR, Kuck JL, Diamond JM, Lederer DJ, Kawut SM, Palmer SM, Wille KM, Weinacker A, Lama VN, Crespo MM, Orens JB, Shah PD, Hage CA, Cantu E 3rd, Porteous MK, Dhillon G, McDyer J, Bastarache JA, Christie JD, Ware LB; Lung Transplant Outcomes Group (LTOG).

JCI Insight. 2018 Jan 25;3(2). pii: 98546. doi: 10.1172/jci.insight.98546. eCollection 2018 Jan 25.

22.

GBT1118, a compound that increases the oxygen affinity of hemoglobin, improves survival in murine hypoxic acute lung injury.

Putz ND, Shaver CM, Dufu K, Li CM, Xu Q, Hutchaleelaha A, Lehrer-Graiwer J, Majka SM, Ware LB, Bastarache JA.

J Appl Physiol (1985). 2018 Apr 1;124(4):899-905. doi: 10.1152/japplphysiol.00079.2017. Epub 2017 Dec 14.

23.

Glucagon-like peptide 1 signaling inhibits allergen-induced lung IL-33 release and reduces group 2 innate lymphoid cell cytokine production in vivo.

Toki S, Goleniewska K, Reiss S, Zhang J, Bloodworth MH, Stier MT, Zhou W, Newcomb DC, Ware LB, Stanwood GD, Galli A, Boyd KL, Niswender KD, Peebles RS Jr.

J Allergy Clin Immunol. 2018 Nov;142(5):1515-1528.e8. doi: 10.1016/j.jaci.2017.11.043. Epub 2018 Jan 10.

PMID:
29331643
24.

Training the next generation of physician researchers - Vanderbilt Medical Scholars Program.

Brown AM, Chipps TM, Gebretsadik T, Ware LB, Islam JY, Finck LR, Barnett J, Hartert TV.

BMC Med Educ. 2018 Jan 4;18(1):5. doi: 10.1186/s12909-017-1103-0.

25.

Novel Method for Noninvasive Sampling of the Distal Airspace in Acute Respiratory Distress Syndrome.

McNeil JB, Shaver CM, Kerchberger VE, Russell DW, Grove BS, Warren MA, Wickersham NE, Ware LB, McDonald WH, Bastarache JA.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1027-1035. doi: 10.1164/rccm.201707-1474OC.

26.

Targeting resolution of pulmonary edema in primary graft dysfunction after lung transplantation: Is inhaled AP301 the answer?

Ware LB.

J Heart Lung Transplant. 2017 Nov 16. pii: S1053-2498(17)32114-9. doi: 10.1016/j.healun.2017.11.013. [Epub ahead of print] No abstract available.

PMID:
29198870
27.

Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin.

Kuck JL, Bastarache JA, Shaver CM, Fessel JP, Dikalov SI, May JM, Ware LB.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):433-437. doi: 10.1016/j.bbrc.2017.11.058. Epub 2017 Nov 9.

28.

Endothelial glycocalyx degradation is more severe in patients with non-pulmonary sepsis compared to pulmonary sepsis and associates with risk of ARDS and other organ dysfunction.

Murphy LS, Wickersham N, McNeil JB, Shaver CM, May AK, Bastarache JA, Ware LB.

Ann Intensive Care. 2017 Oct 6;7(1):102. doi: 10.1186/s13613-017-0325-y.

29.

Cell-Free Hemoglobin-mediated Increases in Vascular Permeability. A Novel Mechanism of Primary Graft Dysfunction and a New Therapeutic Target.

Shaver CM, Wickersham N, McNeil JB, Nagata H, Sills G, Kuck JL, Janz DR, Bastarache JA, Ware LB.

Ann Am Thorac Soc. 2017 Sep;14(Supplement_3):S251-S252. doi: 10.1513/AnnalsATS.201609-693MG.

30.

Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant.

Cantu E, Diamond JM, Suzuki Y, Lasky J, Schaufler C, Lim B, Shah R, Porteous M, Lederer DJ, Kawut SM, Palmer SM, Snyder LD, Hartwig MG, Lama VN, Bhorade S, Bermudez C, Crespo M, McDyer J, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Wilkes D, Roe D, Hage C, Ware LB, Bellamy SL, Christie JD; Lung Transplant Outcomes Group.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):235-243. doi: 10.1164/rccm.201706-1140OC.

31.

Oxygenation Saturation Index Predicts Clinical Outcomes in ARDS.

DesPrez K, McNeil JB, Wang C, Bastarache JA, Shaver CM, Ware LB.

Chest. 2017 Dec;152(6):1151-1158. doi: 10.1016/j.chest.2017.08.002. Epub 2017 Aug 16. Erratum in: Chest. 2018 Mar;153(3):768.

32.

External Validity of Electronic Sniffers for Automated Recognition of Acute Respiratory Distress Syndrome.

McKown AC, Brown RM, Ware LB, Wanderer JP.

J Intensive Care Med. 2017 Jan 1:885066617720159. doi: 10.1177/0885066617720159. [Epub ahead of print]

33.

Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension.

Porteous MK, Lee JC, Lederer DJ, Palmer SM, Cantu E, Shah RJ, Bellamy SL, Lama VN, Bhorade SM, Crespo MM, McDyer JF, Wille KM, Localio AR, Orens JB, Shah PD, Weinacker AB, Arcasoy S, Wilkes DS, Ware LB, Christie JD, Kawut SM, Diamond JM; Lung Transplant Outcomes Group.

Ann Am Thorac Soc. 2017 Oct;14(10):1514-1522. doi: 10.1513/AnnalsATS.201610-810OC.

34.

Clinical trials in acute respiratory distress syndrome: challenges and opportunities.

Matthay MA, McAuley DF, Ware LB.

Lancet Respir Med. 2017 Jun;5(6):524-534. doi: 10.1016/S2213-2600(17)30188-1. Epub 2017 May 26. Review.

PMID:
28664851
35.

A common deletion in the haptoglobin gene associated with blood cholesterol levels among Chinese women.

Zheng NS, Bastarache LA, Bastarache JA, Lu Y, Ware LB, Shu XO, Denny JC, Long J.

J Hum Genet. 2017 Oct;62(10):911-914. doi: 10.1038/jhg.2017.66. Epub 2017 Jun 29.

36.

External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome.

Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB.

Intensive Care Med. 2017 Aug;43(8):1123-1131. doi: 10.1007/s00134-017-4854-5. Epub 2017 Jun 7.

37.

Circulating microparticle levels are reduced in patients with ARDS.

Shaver CM, Woods J, Clune JK, Grove BS, Wickersham NE, McNeil JB, Shemancik G, Ware LB, Bastarache JA.

Crit Care. 2017 May 25;21(1):120. doi: 10.1186/s13054-017-1700-7.

38.

Biomarkers in Critical Illness: New Insights and Challenges for the Future.

Ware LB.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):944-945. doi: 10.1164/rccm.201704-0831ED. No abstract available.

PMID:
28475361
39.

Profiling of ARDS pulmonary edema fluid identifies a metabolically distinct subset.

Rogers AJ, Contrepois K, Wu M, Zheng M, Peltz G, Ware LB, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L703-L709. doi: 10.1152/ajplung.00438.2016. Epub 2017 Mar 3.

40.

Preadmission Oral Corticosteroids Are Associated With Reduced Risk of Acute Respiratory Distress Syndrome in Critically Ill Adults With Sepsis.

McKown AC, McGuinn EM, Ware LB, Wang L, Janz DR, Rice TW, Semler MW.

Crit Care Med. 2017 May;45(5):774-780. doi: 10.1097/CCM.0000000000002286.

41.

Gender Parity in Critical Care Medicine.

Mehta S, Burns KEA, Machado FR, Fox-Robichaud AE, Cook DJ, Calfee CS, Ware LB, Burnham EL, Kissoon N, Marshall JC, Mancebo J, Finfer S, Hartog C, Reinhart K, Maitland K, Stapleton RD, Kwizera A, Amin P, Abroug F, Smith O, Laake JH, Shrestha GS, Herridge MS.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):425-429. doi: 10.1164/rccm.201701-0076CP. Review.

42.

Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries.

Russell DW, Janz DR, Emerson WL, May AK, Bernard GR, Zhao Z, Koyama T, Ware LB.

BMC Pulm Med. 2017 Feb 3;17(1):29. doi: 10.1186/s12890-017-0370-1.

43.

Protein biomarkers associated with primary graft dysfunction following lung transplantation.

Hamilton BC, Kukreja J, Ware LB, Matthay MA.

Am J Physiol Lung Cell Mol Physiol. 2017 Apr 1;312(4):L531-L541. doi: 10.1152/ajplung.00454.2016. Epub 2017 Jan 27. Review.

44.

Primary graft dysfunction: pathophysiology to guide new preventive therapies.

Shaver CM, Ware LB.

Expert Rev Respir Med. 2017 Feb;11(2):119-128. doi: 10.1080/17476348.2017.1280398. Epub 2017 Jan 20. Review.

45.

Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection.

Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP.

Nat Med. 2016 Dec 6;22(12):1502. doi: 10.1038/nm1216-1502d. No abstract available.

46.

Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling.

Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS.

Am J Respir Crit Care Med. 2017 Apr 15;195(8):1010-1021. doi: 10.1164/rccm.201604-0759OC.

47.

Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection.

Zackular JP, Moore JL, Jordan AT, Juttukonda LJ, Noto MJ, Nicholson MR, Crews JD, Semler MW, Zhang Y, Ware LB, Washington MK, Chazin WJ, Caprioli RM, Skaar EP.

Nat Med. 2016 Nov;22(11):1330-1334. doi: 10.1038/nm.4174. Epub 2016 Sep 26. Erratum in: Nat Med. 2016 Dec 6;22(12 ):1502.

48.

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.

Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, Levin AM, Song W, Torres R, Padhukasahasram B, Eng C, Mejia-Mejia DA, Ferguson T, Qin ZS, Scott AF, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Kumar R, Avila PC, Williams LK, Watson H, Ware LB, Olopade C, Olopade O, Oliveira R, Ober C, Nicolae DL, Meyers D, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker E, Araujo MI, Herrera-Paz EF, Gietzen K, Grus WE, Bamshad M, Bustamante CD, Kenny EE, Hernandez RD, Beaty TH, Ruczinski I, Akey J; CAAPA, Barnes KC.

Nat Commun. 2016 Oct 11;7:12522. doi: 10.1038/ncomms12522.

49.

Clinical Predictors of Hospital Mortality Differ Between Direct and Indirect ARDS.

Luo L, Shaver CM, Zhao Z, Koyama T, Calfee CS, Bastarache JA, Ware LB.

Chest. 2017 Apr;151(4):755-763. doi: 10.1016/j.chest.2016.09.004. Epub 2016 Sep 20.

50.

A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury.

Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SS, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR; TRIBE-AKI Consortium * .

Am J Respir Crit Care Med. 2017 Feb 15;195(4):482-490. doi: 10.1164/rccm.201603-0518OC.

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